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Volumn 5, Issue 1, 2003, Pages 30-37

Gene therapy for prostate cancer using the cytosine deaminase/uracil phosphoribosyltransferase suicide system

Author keywords

5 fluorocytosine; Cancer suicide gene therapy; E. coli cytosine deaminase gene; E. coli uracil phosphoribosyltransferase gene; Prostate cancer; Replication defective adenovirus vector

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL; URACIL PHOSPHORIBOSYLTRANSFERASE; ANTINEOPLASTIC ANTIMETABOLITE; DEAMINASE; GLYCOSYLTRANSFERASE;

EID: 0037927844     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.317     Document Type: Article
Times cited : (53)

References (24)
  • 1
    • 0032505770 scopus 로고    scopus 로고
    • Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation
    • Mcmasters RA, Saylors L, Jones KE, et al. Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation. Hum Gene Ther 1998; 9: 2253-2261.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2253-2261
    • McMasters, R.A.1    Saylors, L.2    Jones, K.E.3
  • 2
    • 0032851547 scopus 로고    scopus 로고
    • Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model
    • Shirakawa T, Gardner TA, Ko S, et al. Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model. J Urol 1999; 162: 949-954.
    • (1999) J. Urol. , vol.162 , pp. 949-954
    • Shirakawa, T.1    Gardner, T.A.2    Ko, S.3
  • 3
    • 0032526178 scopus 로고    scopus 로고
    • Preferential cyotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-fluorocytosine
    • Lawrence TS, Rehemtulla A, Ng NY, et al. Preferential cyotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-fluorocytosine. Cancer Res 1998; 58: 2588-2593.
    • (1998) Cancer Res. , vol.58 , pp. 2588-2593
    • Lawrence, T.S.1    Rehemtulla, A.2    Ng, N.Y.3
  • 4
    • 0033696046 scopus 로고    scopus 로고
    • Adenoviral transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil
    • Koyama F, Sawada H, Fujii H, et al. Adenoviral transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil. Eur J Cancer 2000; 36: 2403-2410.
    • (2000) Eur. J. Cancer , vol.36 , pp. 2403-2410
    • Koyama, F.1    Sawada, H.2    Fujii, H.3
  • 5
    • 0032955244 scopus 로고    scopus 로고
    • Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction
    • Inaba M, Sawada H, Sadata A, et al. Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction. Jpn J Cancer Res 1999; 90: 349-354.
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 349-354
    • Inaba, M.1    Sawada, H.2    Sadata, A.3
  • 6
    • 0032080867 scopus 로고    scopus 로고
    • Adenovirus mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil
    • Kanai K, Kawakami T, Hamada H, et al. Adenovirus mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil. Cancer Res 1998; 58: 1946-1951.
    • (1998) Cancer Res. , vol.58 , pp. 1946-1951
    • Kanai, K.1    Kawakami, T.2    Hamada, H.3
  • 7
    • 0034087221 scopus 로고    scopus 로고
    • Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity
    • Kawamura K, Tasaki K, Hamada H, et al. Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity. Cancer Gene Ther 2000; 7: 637-643.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 637-643
    • Kawamura, K.1    Tasaki, K.2    Hamada, H.3
  • 8
    • 0032188845 scopus 로고    scopus 로고
    • Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine
    • Tiraby M, Cazaux C, Baron M, et al. Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine. FEMS Microbiol Lett 1998; 167: 41-49.
    • (1998) FEMS Microbiol. Lett. , vol.167 , pp. 41-49
    • Tiraby, M.1    Cazaux, C.2    Baron, M.3
  • 9
    • 0033958068 scopus 로고    scopus 로고
    • Experimental gene therapy for brain tumors using adenovirus-mediated transfer of cytosine deaminase gene and uracil phosphoribosyltransferase gene with 5-fluorocytosine
    • Adachi Y, Tamiya T, Ichikawa T, et al. Experimental gene therapy for brain tumors using adenovirus-mediated transfer of cytosine deaminase gene and uracil phosphoribosyltransferase gene with 5-fluorocytosine. Hum Gene Ther 2000; 11: 77-89.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 77-89
    • Adachi, Y.1    Tamiya, T.2    Ichikawa, T.3
  • 10
    • 0034660858 scopus 로고    scopus 로고
    • In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene
    • Erbs P, Regulier E, Kintz J, et al. In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene. Cancer Res 2000; 15: 3813-3822.
    • (2000) Cancer Res. , vol.15 , pp. 3813-3822
    • Erbs, P.1    Regulier, E.2    Kintz, J.3
  • 11
    • 0033914616 scopus 로고    scopus 로고
    • Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of Esherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine
    • Koyama F, Sawada H, Hirao T, et al. Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of Esherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine. Cancer Gene Ther 2000; 7: 1015-1022.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1015-1022
    • Koyama, F.1    Sawada, H.2    Hirao, T.3
  • 12
    • 0035158045 scopus 로고    scopus 로고
    • In vivo gene therapy for colon cancer using adenovirus-mediated transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase
    • Chung-Faye CA, Chen MJ, Green NK, et al. In vivo gene therapy for colon cancer using adenovirus-mediated transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase. Gene Ther 2001; 8: 1547-1554.
    • (2001) Gene Ther. , vol.8 , pp. 1547-1554
    • Chung-Faye, C.A.1    Chen, M.J.2    Green, N.K.3
  • 13
    • 0002401080 scopus 로고    scopus 로고
    • Antineoplastic agents
    • (eds). (9th edn). Gilman AG, Rall T, Nies AS, Taylor P (eds). Pergamon Press: New York
    • Galabrisi P, Chabner BA (eds). Antineoplastic agents. In Goodman and Gilman's Pharmacological Basis for Therapeutics (9th edn). Gilman AG, Rall T, Nies AS, Taylor P (eds). Pergamon Press: New York, 1225-1287.
    • Goodman and Gilman's Pharmacological Basis for Therapeutics , pp. 1225-1287
    • Galabrisi, P.1    Chabner, B.A.2
  • 14
    • 0023876379 scopus 로고
    • Circadian rhythm-varying plasma concentration of 5-fluorouracil during a five-day continuous venous infusion at a constant rate in cancer patients
    • Petit E, Milano G, Levi F, et al. Circadian rhythm-varying plasma concentration of 5-fluorouracil during a five-day continuous venous infusion at a constant rate in cancer patients. Cancer Res 1988; 48: 1676-1679.
    • (1988) Cancer Res. , vol.48 , pp. 1676-1679
    • Petit, E.1    Milano, G.2    Levi, F.3
  • 15
    • 0028982820 scopus 로고
    • Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity
    • Etienne MG, Cheradame S, Fischel JL, et al. Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity. J Clin Oncol 1995; 13 1663-1670.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1663-1670
    • Etienne, M.G.1    Cheradame, S.2    Fischel, J.L.3
  • 16
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • Salonga D, Danenberg KD, Johnson M, et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000; 6: 1322-1327.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1322-1327
    • Salonga, D.1    Danenberg, K.D.2    Johnson, M.3
  • 17
    • 0025058867 scopus 로고
    • Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
    • Harris BE, Song R, Soong S, et al. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res 1990; 50: 197-201.
    • (1990) Cancer Res. , vol.50 , pp. 197-201
    • Harris, B.E.1    Song, R.2    Soong, S.3
  • 18
    • 9044250848 scopus 로고    scopus 로고
    • Thymidylate synthetase mRNA level in adenocarcinoma of the stomach: A predictor for primary tumor response and overall survival
    • Lenz HJ, Leichman CG, Danenberg KD, et al. Thymidylate synthetase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. J Clin Oncol 1996; 14: 176-182.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 176-182
    • Lenz, H.J.1    Leichman, C.G.2    Danenberg, K.D.3
  • 19
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion fluorouracil and weekly leucovorin
    • Leichman CG, Lenz HJ, Leichman L, et al. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion fluorouracil and weekly leucovorin. J Clin Oncol 1997; 15: 3223-3229.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 20
    • 0029052988 scopus 로고
    • Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil
    • Copur S, Aiba K, Drake JC, et al. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil. Biochem Pharmacol 1995; 49: 1419-1426.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 1419-1426
    • Copur, S.1    Aiba, K.2    Drake, J.C.3
  • 21
    • 0031845428 scopus 로고    scopus 로고
    • Mechanisms for 5-fluorouracil resistance in human colon cancer DLD-1 cells
    • Inaba M, Naoe Y, Mitsuhashi J. Mechanisms for 5-fluorouracil resistance in human colon cancer DLD-1 cells. Biol Pharm Bull 1998; 21: 569-573.
    • (1998) Biol. Pharm. Bull. , vol.21 , pp. 569-573
    • Inaba, M.1    Naoe, Y.2    Mitsuhashi, J.3
  • 22
    • 0027317751 scopus 로고
    • Decreased folylpolyglutamate synthetase expression: A novel mechanism of fluorouracil resistance
    • Wang FS, Aschele C, Sobrero A, et al. Decreased folylpolyglutamate synthetase expression: a novel mechanism of fluorouracil resistance. Cancer Res 1993; 53: 3677-3680.
    • (1993) Cancer Res. , vol.53 , pp. 3677-3680
    • Wang, F.S.1    Aschele, C.2    Sobrero, A.3
  • 23
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • Huber BE, Austin EA, Richards CA, et al. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci U S A 1994; 91: 8302-8306.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 8302-8306
    • Huber, B.E.1    Austin, E.A.2    Richards, C.A.3
  • 24
    • 0029865182 scopus 로고    scopus 로고
    • Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by camp
    • Mehta PP, Lokeshwar BL, Schiller PC, et al. Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by camp. Mol Carcinogenesis 1996; 15 18-32.
    • (1996) Mol. Carcinogenesis , vol.15 , pp. 18-32
    • Mehta, P.P.1    Lokeshwar, B.L.2    Schiller, P.C.3


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