Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine

FEMS Microbiology Letters

Volumn 167, Issue 1, 1998, Pages 41-49

  Tiraby, Michèle ^a   Cazaux, Christophe ^b   Baron, Michel ^b   Drocourt, Daniel ^a   Reynes, Jean Paul ^a   Tiraby, Gérard ^b  

^a CAYLA   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

5 Fluorocytosine; Cytosine deaminase; Escherichia coli; Suicide gene; Uracil phosphoribosyltransferase

Indexed keywords

CYTOSINE DEAMINASE; FLUCYTOSINE; PRODRUG; URACIL PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CYTOTOXICITY; DRUG ACTIVATION; DRUG SENSITIVITY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUICIDE GENE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ARTIFICIAL GENE FUSION; CYTOSINE DEAMINASE; DRUG RESISTANCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLUCYTOSINE; FLUOROURACIL; GENE EXPRESSION; GENES, BACTERIAL; MUTATION; NEOPLASMS, EXPERIMENTAL; NUCLEOSIDE DEAMINASES; PENTOSYLTRANSFERASES; PRODRUGS;

EID: 0032188845     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(98)00365-6     Document Type: Article

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