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Volumn 2, Issue 3, 2003, Pages 369-379

Vaccination with heat shock protein-peptide complexes: From basic science to clinical applications

Author keywords

Aurologous cancer vaccine; Heat shock protiens; Immunotherapy; Translational medicine

Indexed keywords

AG 702; CANCER VACCINE; HEAT SHOCK PROTEIN E7; HEAT SHOCK PROTEIN PEPTIDE COMPLEX 70; HEAT SHOCK PROTEIN PEPTIDE COMPLEX 96; IMATINIB; ONCOPHAGE; RECOMBINANT VACCINE; UNCLASSIFIED DRUG;

EID: 0037833596     PISSN: 14760584     EISSN: None     Source Type: Journal    
DOI: 10.1586/14760584.2.3.369     Document Type: Review
Times cited : (68)

References (76)
  • 1
    • 0021339151 scopus 로고
    • Serologically unique surface antigen of a rat hepatoma is also its tumor-associated transplantation antigen
    • Srivastava PK, Das MR. Serologically unique surface antigen of a rat hepatoma is also its tumor-associated transplantation antigen. Int. J. Cancer 33 (3), 417-422 (1984).
    • (1984) Int. J. Cancer , vol.33 , Issue.3 , pp. 417-422
    • Srivastava, P.K.1    Das, M.R.2
  • 2
    • 0022534393 scopus 로고
    • Tumor rejection antigens of chemically induced sarcomas of inbred mice
    • Srivastava PK, DeLeo AB, Old LJ. 1986. Tumor rejection antigens of chemically induced sarcomas of inbred mice. Proc. Natl Acad. Sci. USA 83(10), 3407-3411 (1986).
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , Issue.10 , pp. 3407-3411
    • Srivastava, P.K.1    DeLeo, A.B.2    Old, L.J.3
  • 4
    • 0034252699 scopus 로고    scopus 로고
    • gp96 - The immune system's Swiss army knife
    • Schild H, Rammensee HG. gp96 - the immune system's Swiss army knife. Nat. Immunol. 1(2), 100-101 (2000).
    • (2000) Nat. Immunol. , vol.1 , Issue.2 , pp. 100-101
    • Schild, H.1    Rammensee, H.G.2
  • 5
    • 0001871368 scopus 로고
    • The history of cancer immunotherapy
    • Devita VT, Hellman S, Rosenberg SA (Eds). JB Lippincott, London, UK
    • Oettgen HF, Old LJ. The history of cancer immunotherapy. In: Biologic Therapy of Cancer. Devita VT, Hellman S, Rosenberg SA (Eds). JB Lippincott, London, UK, 87-119 (1991).
    • (1991) Biologic Therapy of Cancer , pp. 87-119
    • Oettgen, H.F.1    Old, L.J.2
  • 6
    • 0001739064 scopus 로고
    • Intradermal immunization of C 3H mice against a sarcoma that originated in an animal of the same line
    • Gross L. Intradermal immunization of C3H mice against a sarcoma that originated in an animal of the same line. Cancer Res. 3, 323-326 (1943).
    • (1943) Cancer Res. , vol.3 , pp. 323-326
    • Gross, L.1
  • 8
    • 70449193189 scopus 로고
    • Immunity to methylcholanthrene-induced sarcomas
    • Prehn R, Main JM. Immunity to methylcholanthrene-induced sarcomas. J. Natl Cancer Inst. 18, 769-778 (1957).
    • (1957) J. Natl Cancer Inst. , vol.18 , pp. 769-778
    • Prehn, R.1    Main, J.M.2
  • 9
    • 78651120598 scopus 로고
    • Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host
    • Klein G, Sjorgen HO, Klein E, Hellstrom KE. Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host. Cancer Res. 20, 1561-1572 (1960).
    • (1960) Cancer Res. , vol.20 , pp. 1561-1572
    • Klein, G.1    Sjorgen, H.O.2    Klein, E.3    Hellstrom, K.E.4
  • 10
    • 0030272588 scopus 로고    scopus 로고
    • Do human cancers express shared protective antigens? Or the necessity of remembrance of things past
    • Srivastava PK. Do human cancers express shared protective antigens? Or the necessity of remembrance of things past. Semin. Immunol. 8(5), 295-302 (1997).
    • (1997) Semin. Immunol. , vol.8 , Issue.5 , pp. 295-302
    • Srivastava, P.K.1
  • 11
    • 0034328883 scopus 로고    scopus 로고
    • Immunotherapy of human cancer: Lessons from mice
    • Srivastava PK. Immunotherapy of human cancer: lessons from mice. Nat. Immunol. 1(5), 363-366 (2000).
    • (2000) Nat. Immunol. , vol.1 , Issue.5 , pp. 363-366
    • Srivastava, P.K.1
  • 12
    • 0023228980 scopus 로고
    • 5′-structural analysis of genes encoding polymorphic antigens of chemically induced tumors
    • Srivastava PK, Chen YT, Old LJ. 5′-structural analysis of genes encoding polymorphic antigens of chemically induced tumors. Proc. Natl Acad. Sci. USA 84(11), 3807-3811 (1987).
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , Issue.11 , pp. 3807-3811
    • Srivastava, P.K.1    Chen, Y.T.2    Old, L.J.3
  • 13
  • 14
    • 0036214288 scopus 로고    scopus 로고
    • Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
    • Srivastava PK. Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Ann. Rev. Immunol. 20, 395-425 (2002).
    • (2002) Ann. Rev. Immunol. , vol.20 , pp. 395-425
    • Srivastava, P.K.1
  • 15
    • 0029937037 scopus 로고    scopus 로고
    • Structural analysis of substrate binding by the molecular chaperone DnaK
    • Zhu X, Zhao X, Burkholder WF et al. Structural analysis of substrate binding by the molecular chaperone DnaK. Science 272(5268), 1606-1614 (1996).
    • (1996) Science , vol.272 , Issue.5268 , pp. 1606-1614
    • Zhu, X.1    Zhao, X.2    Burkholder, W.F.3
  • 16
    • 0036512171 scopus 로고    scopus 로고
    • Roles of heat-shock proteins in innate and adaptive immunity
    • Srivastava PK. Roles of heat-shock proteins in innate and adaptive immunity. Nat. Rev. Immunol. 2, 185-194 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 185-194
    • Srivastava, P.K.1
  • 18
    • 0028366212 scopus 로고
    • Heat shock proteins transfer peptides during antigen processing and CTL priming
    • Srivastava PK, Udono H, Blachere NE, Li Z. Heat shock proteins transfer peptides during antigen processing and CTL priming. Immunogenetics 39(2), 93-98 (1994).
    • (1994) Immunogenetics , vol.39 , Issue.2 , pp. 93-98
    • Srivastava, P.K.1    Udono, H.2    Blachere, N.E.3    Li, Z.4
  • 19
    • 0034252620 scopus 로고    scopus 로고
    • CD91: A receptor for heat shock protein gp96
    • Binder RJ, Han DK, Srivastava PK. CD91: a receptor for heat shock protein gp96. Nat. Immunol. 1(2), 151-155 (2000).
    • (2000) Nat. Immunol. , vol.1 , Issue.2 , pp. 151-155
    • Binder, R.J.1    Han, D.K.2    Srivastava, P.K.3
  • 20
    • 0035070198 scopus 로고    scopus 로고
    • CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
    • Basu S, Binder RJ, Ramalingam T, Srivastava PK. CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity 14(3), 303-313 (2001).
    • (2001) Immunity , vol.14 , Issue.3 , pp. 303-313
    • Basu, S.1    Binder, R.J.2    Ramalingam, T.3    Srivastava, P.K.4
  • 21
    • 0037080218 scopus 로고    scopus 로고
    • The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins
    • Habich C, Baumgart K, Kolb H, Burkart V. The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins J. Immunol. 168, 569-576 (2002).
    • (2002) J. Immunol. , vol.168 , pp. 569-576
    • Habich, C.1    Baumgart, K.2    Kolb, H.3    Burkart, V.4
  • 22
  • 23
    • 0037443410 scopus 로고    scopus 로고
    • Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
    • Skokos D, Botros HG, Demeure C et al. Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J. Immunol. 170 (6), 3037-3045 (2003).
    • (2003) J. Immunol. , vol.170 , Issue.6 , pp. 3037-3045
    • Skokos, D.1    Botros, H.G.2    Demeure, C.3
  • 24
    • 0036569356 scopus 로고    scopus 로고
    • Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides
    • Berwin B, Hart JP, Pizzo SV, Nicchitta CV. Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides. J. Immunol. 168(9), 4282-4286 (2002).
    • (2002) J. Immunol. , vol.168 , Issue.9 , pp. 4282-4286
    • Berwin, B.1    Hart, J.P.2    Pizzo, S.V.3    Nicchitta, C.V.4
  • 25
    • 0028979675 scopus 로고
    • A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
    • Suto R, Srivastava PK. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. Science 269(5230), 1585-1588 (1995).
    • (1995) Science , vol.269 , Issue.5230 , pp. 1585-1588
    • Suto, R.1    Srivastava, P.K.2
  • 27
    • 0030775140 scopus 로고    scopus 로고
    • Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity
    • Blachere NE, Li Z, Chandawarkar RY et al. Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity. J. Exp. Med. 186(8), 1315-1322 (1997). This study definitively demonstrated the adjuvant activity of mammalian HSPs. CTL response was shown to be induced to multiple antigens complexed to HSPs.
    • (1997) J. Exp. Med. , vol.186 , Issue.8 , pp. 1315-1322
    • Blachere, N.E.1    Li, Z.2    Chandawarkar, R.Y.3
  • 28
    • 0037086266 scopus 로고    scopus 로고
    • Development of a recombinant HSP110-HER-2/neu vaccine using the chaperoning properties of HSP110
    • Manjili MH, Henderson R, Wang XY et al. Development of a recombinant HSP110-HER-2/neu vaccine using the chaperoning properties of HSP110. Cancer Res. 62(6), 1737-1742 (2002).
    • (2002) Cancer Res. , vol.62 , Issue.6 , pp. 1737-1742
    • Manjili, M.H.1    Henderson, R.2    Wang, X.Y.3
  • 29
    • 0030028801 scopus 로고    scopus 로고
    • Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24
    • Suzue K, Young RA. Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24. J. Immunol. 156(2), 873-879 (1996).
    • (1996) J. Immunol. , vol.156 , Issue.2 , pp. 873-879
    • Suzue, K.1    Young, R.A.2
  • 30
    • 0033838826 scopus 로고    scopus 로고
    • Immunotherapy of a human papillomavirus (HPV) Type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7
    • Chu NR, Wu HB, Wu T, Boux LJ, Siegel MI, Mizzen LA. Immunotherapy of a human papillomavirus (HPV) Type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7. Clin. Exp. Immunol. 121(2), 216-225 (2000).
    • (2000) Clin. Exp. Immunol. , vol.121 , Issue.2 , pp. 216-225
    • Chu, N.R.1    Wu, H.B.2    Wu, T.3    Boux, L.J.4    Siegel, M.I.5    Mizzen, L.A.6
  • 31
    • 0345164329 scopus 로고    scopus 로고
    • + CTL effector cells in mice by immunization with a stress protein-influenza virus nucleoprotein fusion molecule
    • + CTL effector cells in mice by immunization with a stress protein-influenza virus nucleoprotein fusion molecule. Vaccine 17(4), 373-383 (1999).
    • (1999) Vaccine , vol.17 , Issue.4 , pp. 373-383
    • Anthony, L.S.1    Wu, H.2    Sweet, H.3
  • 32
    • 0034782206 scopus 로고    scopus 로고
    • Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70
    • Udono H, Yamano T, Kawabata Y, Ueda M, Yui K. Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70. Int. Immunol. 13(10), 1233-1242 (2001).
    • (2001) Int. Immunol. , vol.13 , Issue.10 , pp. 1233-1242
    • Udono, H.1    Yamano, T.2    Kawabata, Y.3    Ueda, M.4    Yui, K.5
  • 33
    • 0038019529 scopus 로고    scopus 로고
    • Induction of HBcAg-specific CTL responses by a heat shock protein fused to the core antigen of the Hepatitis B virus
    • Baltimore, MD, USA
    • Anthony LS, Liu H, Rowse G et al. Induction of HBcAg-specific CTL responses by a heat shock protein fused to the core antigen of the Hepatitis B virus. Proceedings of the 5th Annual Conference on Vaccine Research, Baltimore, MD, USA (2002).
    • (2002) Proceedings of the 5th Annual Conference on Vaccine Research
    • Anthony, L.S.1    Liu, H.2    Rowse, G.3
  • 34
    • 0033747044 scopus 로고    scopus 로고
    • Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
    • Basu S, Binder RJ, Suto R, Anderson KM, Srivastava PK. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway. Int. Immunol. 12(11), 1539-1546 (2000).
    • (2000) Int. Immunol. , vol.12 , Issue.11 , pp. 1539-1546
    • Basu, S.1    Binder, R.J.2    Suto, R.3    Anderson, K.M.4    Srivastava, P.K.5
  • 35
    • 0033839045 scopus 로고    scopus 로고
    • The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor
    • Singh-Jasuja H, Scherer HU, Hilf N et al. The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor. Eur. J. Immunol. 30(18), 2211-2215 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , Issue.18 , pp. 2211-2215
    • Singh-Jasuja, H.1    Scherer, H.U.2    Hilf, N.3
  • 36
    • 0033976502 scopus 로고    scopus 로고
    • Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity
    • Lehner T, Bergmeier LA, Wang Y et al. Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity. Eur. J. Immunol. 30(2), 594-603 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , Issue.2 , pp. 594-603
    • Lehner, T.1    Bergmeier, L.A.2    Wang, Y.3
  • 37
    • 0037087398 scopus 로고    scopus 로고
    • Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs
    • Panjwani NN, Popova L, Srivastava PK. Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs. J. Immunol. 168(6), 2997-3003 (2002).
    • (2002) J. Immunol. , vol.168 , Issue.6 , pp. 2997-3003
    • Panjwani, N.N.1    Popova, L.2    Srivastava, P.K.3
  • 38
    • 0033559496 scopus 로고    scopus 로고
    • Human 60-kDa heat-shock protein: A danger signal to the innate immune system
    • Chen W, Syldath U, Bellmann K, Burkart V, Kolb H. Human 60-kDa heat-shock protein: a danger signal to the innate immune system. J. Immunol. 162(6), 3212-3219 (1999).
    • (1999) J. Immunol. , vol.162 , Issue.6 , pp. 3212-3219
    • Chen, W.1    Syldath, U.2    Bellmann, K.3    Burkart, V.4    Kolb, H.5
  • 39
    • 0030820099 scopus 로고    scopus 로고
    • Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations
    • Tamura Y, Peng P, Liu K, Daou M, Srivastava PK. Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations. Science 278(5335), 117-120 (1997).
    • (1997) Science , vol.278 , Issue.5335 , pp. 117-120
    • Tamura, Y.1    Peng, P.2    Liu, K.3    Daou, M.4    Srivastava, P.K.5
  • 40
    • 0034541171 scopus 로고    scopus 로고
    • + cells in vivo
    • + cells in vivo. J. Immunol. 165(11), 6029-6035 (2000). This study demonstrated the ability of intradermally injected HSPs to mobilize and mature DCs in vivo as shown visually and in functional assays.
    • (2000) J. Immunol. , vol.165 , Issue.11 , pp. 6029-6035
    • Binder, R.J.1    Anderson, K.M.2    Basu, S.3    Srivastava, P.K.4
  • 41
    • 0028301079 scopus 로고
    • Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp 90, and hsp70
    • Udono H, Srivastava PK. Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70. J. Immunol. 152, 5398-5403 (1994).
    • (1994) J. Immunol. , vol.152 , pp. 5398-5403
    • Udono, H.1    Srivastava, P.K.2
  • 42
    • 0036219012 scopus 로고    scopus 로고
    • Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses
    • Ciupitu AM, Petersson M, Kono K, Charo J, Kiessling R. Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses. Cancer Immunol. Immunother. 51, 163-170 (2002).
    • (2002) Cancer Immunol. Immunother. , vol.51 , pp. 163-170
    • Ciupitu, A.M.1    Petersson, M.2    Kono, K.3    Charo, J.4    Kiessling, R.5
  • 43
    • 0037011072 scopus 로고    scopus 로고
    • GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression
    • Baker-LePain JC, Sarzotti M, Fields TA, Li CY, Nicchitta CV. GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. J. Exp. Med. 196(11), 1447-1459 (2002).
    • (2002) J. Exp. Med. , vol.196 , Issue.11 , pp. 1447-1459
    • Baker-LePain, J.C.1    Sarzotti, M.2    Fields, T.A.3    Li, C.Y.4    Nicchitta, C.V.5
  • 44
    • 0033819308 scopus 로고    scopus 로고
    • Immunization of cancer patients with autologous cancer-derived heat shock protein gp96: A pilot study
    • Janetzki S, Polla D, Rosenhauer V, Lochs H, Lewis JJ, Srivastava PK. Immunization of cancer patients with autologous cancer-derived heat shock protein gp96: A pilot study. Int. J. Cancer 88(2), 232-238, (2000).
    • (2000) Int. J. Cancer , vol.88 , Issue.2 , pp. 232-238
    • Janetzki, S.1    Polla, D.2    Rosenhauer, V.3    Lochs, H.4    Lewis, J.J.5    Srivastava, P.K.6
  • 45
    • 0035132104 scopus 로고    scopus 로고
    • Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells
    • Castelli C, Ciupitu AM, Rini F et al. Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells. Cancer Res. 61(1), 222-227 (2001). This study is the first demonstration in a human system that HSP-peptide complexes purified from tumor cells can activate CTL clones specific for defined tumor antigens.
    • (2001) Cancer Res. , vol.61 , Issue.1 , pp. 222-227
    • Castelli, C.1    Ciupitu, A.M.2    Rini, F.3
  • 46
    • 0037111218 scopus 로고    scopus 로고
    • Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells
    • Noessner E, Gastpar R, Milani V et al. Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J. Immunol. 169(10), 5424-5432 (2002).
    • (2002) J. Immunol. , vol.169 , Issue.10 , pp. 5424-5432
    • Noessner, E.1    Gastpar, R.2    Milani, V.3
  • 47
    • 0034672104 scopus 로고    scopus 로고
    • Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer
    • Triozzi PL, Khurram R, Aldrich WA, Walker MJ, Kim JA, Jaynes S. Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer. Cancer 89(12), 2646-2654 (2000).
    • (2000) Cancer , vol.89 , Issue.12 , pp. 2646-2654
    • Triozzi, P.L.1    Khurram, R.2    Aldrich, W.A.3    Walker, M.J.4    Kim, J.A.5    Jaynes, S.6
  • 49
    • 0035901097 scopus 로고    scopus 로고
    • HBV-specific peptide associated with heat-shock protein gp96
    • Meng SD, Gao T, Gao GF, Tien P. HBV-specific peptide associated with heat-shock protein gp96. Lancet 357(9255), 528-529 (2001).
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 528-529
    • Meng, S.D.1    Gao, T.2    Gao, G.F.3    Tien, P.4
  • 50
    • 0037108696 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: Clinical and immunologic findings
    • Belli F, Testori A, Rivoltini L et al. Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. J. Clin. Oncol. 20, 4169-4180 (2002). This publication marked one of the first demonstrations of complete dinical response in metastatic melanoma patients using a monotherapy with minimal toxicities.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4169-4180
    • Belli, F.1    Testori, A.2    Rivoltini, L.3
  • 51
    • 10744233222 scopus 로고    scopus 로고
    • Vaccination with autologous tumor derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer
    • In press
    • Mazzaferro V, Coppa J, Carraba MG et al. Vaccination with autologous tumor derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer. Clin. Cancer Res. (2003) (In press).
    • (2003) Clin. Cancer Res.
    • Mazzaferro, V.1    Coppa, J.2    Carraba, M.G.3
  • 52
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
    • Asea A, Kraeft SK, Kurt-Jones EA et al. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 6(4), 435-442 (2000).
    • (2000) Nat. Med. , vol.6 , Issue.4 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3
  • 53
    • 0033975855 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for hsp60 activation of mononuclear cells
    • Kol A, Lichtman AH, Finberg RW, Libby P, Kurt-Jones EA. Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for hsp60 activation of mononuclear cells. J. Immunol. 164(1), 13-17 (2000).
    • (2000) J. Immunol. , vol.164 , Issue.1 , pp. 13-17
    • Kol, A.1    Lichtman, A.H.2    Finberg, R.W.3    Libby, P.4    Kurt-Jones, E.A.5
  • 54
    • 0035500779 scopus 로고    scopus 로고
    • Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells
    • Somersan S, Larsson M, Fontenau JF, Basu S, Srivastava P, Bhardwaj N. Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells. J. Immunol. 167(9), 4544-4852 (2001).
    • (2001) J. Immunol. , vol.167 , Issue.9 , pp. 4544-4852
    • Somersan, S.1    Larsson, M.2    Fontenau, J.F.3    Basu, S.4    Srivastava, P.5    Bhardwaj, N.6
  • 55
    • 0036236563 scopus 로고    scopus 로고
    • Quality of life in patients with metastatic renal cell carcinoma participating in a Phase I trial of an autologous tumor-derived vaccine
    • Cohen L, de Moor C, Parker PA, Amato, RJ. Quality of life in patients with metastatic renal cell carcinoma participating in a Phase I trial of an autologous tumor-derived vaccine. Urol. Oncol. 7, 119-124 (2002).
    • (2002) Urol. Oncol. , vol.7 , pp. 119-124
    • Cohen, L.1    De Moor, C.2    Parker, P.A.3    Amato, R.J.4
  • 56
    • 0038357723 scopus 로고    scopus 로고
    • Active specific immunotherapy in patients with renal cell carcinoma (RCC) using autologous tumor derived heat shock protein-peptide complex-96 (HSPPC-96) with or without interleukin-2
    • New Orleans, LA, USA
    • Amato RJ, Wood LS, Savary C et al. Active specific immunotherapy in patients with renal cell carcinoma (RCC) using autologous tumor derived heat shock protein-peptide complex-96 (HSPPC-96) with or without interleukin-2. Proceedings of the American Society of Clinical Oncology., New Orleans, LA, USA, 1782 (2000).
    • (2000) Proceedings of the American Society of Clinical Oncology , pp. 1782
    • Amato, R.J.1    Wood, L.S.2    Savary, C.3
  • 57
    • 0000768963 scopus 로고    scopus 로고
    • Active specific immunotherapy in patients with renal cell carcinoma (RCC) using autologous tumor derived heat shock protein-peptide complex-96 (HSPPC-96) vaccine
    • Atlanta, GA, USA
    • Amato RJ, Murray L, Wood L, Savary C, Tomasovic S, Reitsma D. Active specific immunotherapy in patients with renal cell carcinoma (RCC) using autologous tumor derived heat shock protein-peptide complex-96 (HSPPC-96) vaccine. Proceedings of the American Society of Clinical Oncology, Atlanta, GA, USA, 1278 (1999).
    • (1999) Proceedings of the American Society of Clinical Oncology , pp. 1278
    • Amato, R.J.1    Murray, L.2    Wood, L.3    Savary, C.4    Tomasovic, S.5    Reitsma, D.6
  • 58
    • 0001748244 scopus 로고    scopus 로고
    • Autologous tumor-derived heat shock protein-peptide complex-96 (HSPPC-96) in patients with metastatic melanoma
    • San Francisco, CA, USA
    • Eton O, East M, Ross MI et al. Autologous tumor-derived heat shock protein-peptide complex-96 (HSPPC-96) in patients with metastatic melanoma. Proceedings of the American Association for Cancer Research, San Francisco, CA, USA, 3463 (2000).
    • (2000) Proceedings of the American Association for Cancer Research , pp. 3463
    • Eton, O.1    East, M.2    Ross, M.I.3
  • 59
    • 0038357724 scopus 로고    scopus 로고
    • Pilot trial of vaccination with autologous tumor-derived gp96 heat shock proteinpeptide complex (HSPPC-96) in patients after surgery for gastric carcinoma
    • New Orleans, LA, USA
    • Heike M, Hertkorn C, Reitsma DJ et al. Pilot trial of vaccination with autologous tumor-derived gp96 heat shock proteinpeptide complex (HSPPC-96) in patients after surgery for gastric carcinoma. Proceedings of the American Society of Clinical Oncology, New Orleans, LA, USA, 1825 (2000).
    • (2000) Proceedings of the American Society of Clinical Oncology , pp. 1825
    • Heike, M.1    Hertkorn, C.2    Reitsma, D.J.3
  • 60
    • 0003207393 scopus 로고    scopus 로고
    • Pilot trial of vaccination with autologous tumor derived gp96 heat shock protein-peptide complex-96 (HSPPC-96) in patients with resected pancreatic adenocarcinoma
    • Atlanta, GA, USA
    • Lewis JJ, Janetzki S, Livingston PO. Pilot trial of vaccination with autologous tumor derived gp96 heat shock protein-peptide complex-96 (HSPPC-96) in patients with resected pancreatic adenocarcinoma. Proceedings of the American Society of Clinical Oncology, Atlanta, GA, USA, 1687 (1999).
    • (1999) Proceedings of the American Society of Clinical Oncology , pp. 1687
    • Lewis, J.J.1    Janetzki, S.2    Livingston, P.O.3
  • 61
    • 0036114412 scopus 로고    scopus 로고
    • Activity of HspE7, a novel immunotherapy, in patients with anogenital warts
    • Goldstone SE, Palefsky JM, Winnett MT, Neefe JR, Activity of HspE7, a novel immunotherapy, in patients with anogenital warts. Dis. Colon Rectum 45(4), 502-507 (2002).
    • (2002) Dis. Colon Rectum , vol.45 , Issue.4 , pp. 502-507
    • Goldstone, S.E.1    Palefsky, J.M.2    Winnett, M.T.3    Neefe, J.R.4
  • 62
    • 0035167866 scopus 로고    scopus 로고
    • Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity
    • Wang XY, Kazim L, Repasky EA, Subjeck JR. Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity. J. Immunol. 166(1), 490-497 (2001).
    • (2001) J. Immunol. , vol.166 , Issue.1 , pp. 490-497
    • Wang, X.Y.1    Kazim, L.2    Repasky, E.A.3    Subjeck, J.R.4
  • 64
    • 0023203359 scopus 로고
    • Expression of a shared tumor-specific antigen by two chemically induced BALB/c sarcomas. I. Detection by a cloned cytotoxic T cell line
    • Palladino MA, Srivastava PK, Oettgen HF, DeLeo AB. Expression of a shared tumor-specific antigen by two chemically induced BALB/c sarcomas. I. Detection by a cloned cytotoxic T cell line. Cancer Res. 47(19), 5074-5079 (1987).
    • (1987) Cancer Res. , vol.47 , Issue.19 , pp. 5074-5079
    • Palladino, M.A.1    Srivastava, P.K.2    Oettgen, H.F.3    DeLeo, A.B.4
  • 65
    • 0031869460 scopus 로고    scopus 로고
    • Generation of tumor-specific cytotoxic T lymphocytes and memory T cells by immunization with tumor-derived heat shock protein gp96
    • Janetzki S, Blachere NF, Srivastava PK. Generation of tumor-specific cytotoxic T lymphocytes and memory T cells by immunization with tumor-derived heat shock protein gp96. J. Immunother. 21(4), 269-276 (1998).
    • (1998) J. Immunother. , vol.21 , Issue.4 , pp. 269-276
    • Janetzki, S.1    Blachere, N.F.2    Srivastava, P.K.3
  • 66
    • 0032007324 scopus 로고    scopus 로고
    • Biochemical cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96
    • Nicchitta CV. Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96. Curr. Opin. Immunol. 10(1), 103-109 (1998).
    • (1998) Curr. Opin. Immunol. , vol.10 , Issue.1 , pp. 103-109
    • Nicchitta, C.V.1
  • 67
    • 0033762022 scopus 로고    scopus 로고
    • Tumor-derived multiple chaperone enrichment by free-solution isoelectric focusing yields potent antitumor vaccines
    • Graner M, Raymond A, Akporiaye E, Katsanis E. Tumor-derived multiple chaperone enrichment by free-solution isoelectric focusing yields potent antitumor vaccines. Cancer Immunol. Immunother. 49(9), 476-484 (2000).
    • (2000) Cancer Immunol. Immunother. , vol.49 , Issue.9 , pp. 476-484
    • Graner, M.1    Raymond, A.2    Akporiaye, E.3    Katsanis, E.4
  • 68
    • 0035885969 scopus 로고    scopus 로고
    • Immunotherapy using heat-shock protein preparations of leukemia cells after syngeneic bone marrow transplantation in mice
    • Sato K, Torimoto Y, Tamura Y et al. Immunotherapy using heat-shock protein preparations of leukemia cells after syngeneic bone marrow transplantation in mice. Blood 98 (6), 1852-1857 (2001).
    • (2001) Blood , vol.98 , Issue.6 , pp. 1852-1857
    • Sato, K.1    Torimoto, Y.2    Tamura, Y.3
  • 69
    • 0035133401 scopus 로고    scopus 로고
    • Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70
    • Robert J, Menoret A, Basu S, Cohen N, Srivastava PK. Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70. Eur. J. Immunol. 31(1), 186-195 (2001). This study provides a convincing example, in a model of tumor immunity in Xenopus, of the conservation of immunological functions of HSPs through evolution.
    • (2001) Eur. J. Immunol. , vol.31 , Issue.1 , pp. 186-195
    • Robert, J.1    Menoret, A.2    Basu, S.3    Cohen, N.4    Srivastava, P.K.5
  • 70
    • 0033194498 scopus 로고    scopus 로고
    • Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model
    • Yedavelli SPK, Guo L, Daou ME, Srivastava PK. Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model. Int. J. Mol. Med. 4(3), 243-248 (1999).
    • (1999) Int. J. Mol. Med. , vol.4 , Issue.3 , pp. 243-248
    • Yedavelli, S.P.K.1    Guo, L.2    Daou, M.E.3    Srivastava, P.K.4
  • 72
    • 0030877759 scopus 로고    scopus 로고
    • Generation of heat shock protein-based vaccines by intra cellular loading of gp96 with antigenic peptides
    • Heikema A, Agsteribbe E, Wiscjut J, Huckriede A. Generation of heat shock protein-based vaccines by intracellular loading of gp96 with antigenic peptides. Immunol. Lett. 57(1-3), 69-74 (1997).
    • (1997) Immunol. Lett. , vol.57 , Issue.1-3 , pp. 69-74
    • Heikema, A.1    Agsteribbe, E.2    Wiscjut, J.3    Huckriede, A.4
  • 73
    • 0036133062 scopus 로고    scopus 로고
    • Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection
    • Kumaraguru U, Gierynska M, Norman S, Bruce BD, Rouse BT. Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection. J. Virol. 76(1), 136-141 (2002).
    • (2002) J. Virol. , vol.76 , Issue.1 , pp. 136-141
    • Kumaraguru, U.1    Gierynska, M.2    Norman, S.3    Bruce, B.D.4    Rouse, B.T.5
  • 74
    • 0032473485 scopus 로고    scopus 로고
    • Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity and specific cytotoxic T lymphocytes
    • Ciupitu AM, Petersson M, O'Donnell CL, et al. Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity and specific cytotoxic T lymphocytes. J. Exp. Med. 187(5), 685-691 (1998). This study is the first demonstration that HSP-peptide complexes provide protective immunity to challenge with live virus in a murine model.
    • (1998) J. Exp. Med. , vol.187 , Issue.5 , pp. 685-691
    • Ciupitu, A.M.1    Petersson, M.2    O'Donnell, C.L.3
  • 75
    • 0035825064 scopus 로고    scopus 로고
    • Heat shock protein-peptide complexes elicit cytotoxic T-lymphocyte and antibody responses specific for bovine herpesvirus 1
    • Navaratnam M, Deshpande MS, Hariharan MJ, Zatechka DS, Srikumaran S. Heat shock protein-peptide complexes elicit cytotoxic T-lymphocyte and antibody responses specific for bovine herpesvirus 1. Vaccine 19(11-12), 1425-1434 (2001).
    • (2001) Vaccine , vol.19 , Issue.11-12 , pp. 1425-1434
    • Navaratnam, M.1    Deshpande, M.S.2    Hariharan, M.J.3    Zatechka, D.S.4    Srikumaran, S.5


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