Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

FEBS Letters

Volumn 546, Issue 2-3, 2003, Pages 300-306

  Hatse, Sigrid ^a   Princen, Katrien ^a   Vermeire, Kurt ^a   Gerlach, Lars Ole ^b   Rosenkilde, Mette M ^b   Schwartz, Thue W ^b   Bridger, Gary ^c   De Clercq, Erik ^a   Schols, Dominique ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c GENZYME CORPORATION   (United States)

Author keywords

Antibody recognition; Bicyclam; CXCR4; Human immunodeficiency virus coreceptor; Resistance

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ASPARAGINE; ASPARTIC ACID; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTIBODY; GLYCOPROTEIN GP 130; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; ASTROCYTOMA; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS INFECTIVITY; VIRUS ISOLATION; VIRUS RESISTANCE; VIRUS STRAIN; WILD TYPE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037832482     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(03)00609-4     Document Type: Article

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