Molecular cloning of the feline telomerase reverse transcriptase (TERT) gene and its expression in cell lines and normal tissues

Journal of Veterinary Medical Science

Volumn 65, Issue 5, 2003, Pages 573-577

  Yazawa, Mitsuhiro ^a   Okuda, Masaru ^b   Uyama, Rina ^a   Nakagawa, Takayuki ^a   Kanaya, Noriko ^a   Nishimura, Ryohei ^a   Sasaki, Nobuo ^a   Masuda, Kenichi ^a   Ohno, Koichi ^a   Tsujimoto, Hajime ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Cloning; Expression; Feline; Telomerase; TERT

Indexed keywords

FELIDAE;

COMPLEMENTARY DNA; DNA BINDING PROTEIN; MESSENGER RNA; TELOMERASE; TERT PROTEIN, HUMAN; TERT PROTEIN, MOUSE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BRAIN; CAT; CELL LINE; CHEMISTRY; DIGESTIVE SYSTEM; GENE EXPRESSION PROFILING; GENETICS; LYMPHOID TISSUE; MALE; METABOLISM; MOLECULAR GENETICS; TESTIS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CATS; CELL LINE; DIGESTIVE SYSTEM; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; LYMPHOID TISSUE; MALE; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; TELOMERASE; TESTIS;

EID: 0037828694     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.65.573     Document Type: Article

References (30)

1. Allsopp, R. C., Vaziri, H., Patterson, C., Goldstein, S., Younglai, E. V., Futcher, A. B., Greider, C. W. and Harley, C. B. 1992. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. U. S. A. 89: 10114-10118.
2. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D. J. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402.
3. Blackburn, E. H. 1984. The molecular structure of centromeres and telomeres. Annu. Rev. Biochem. 53: 163-194.
4. Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C. P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S. and Wright, W. E. 1998. Extension of life-span by introduction of telomerase into normal human cells. Science 279: 349-352.
5. Bryan, T. M., Englezou, A., Dalla-Pozza, L., Dunham, M. A. and Reddel, R. R. 1997. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 3: 1271-1274.
6. Cadile, C. D., Kitchell, B. E., Biller, B. J., Hetler, E. R. and Balkin, R. G. 2001. Telomerase activity as a marker for malignancy in feline tissues. Am. J. Vet. Res. 62: 1578-1581.
7. Cockerell, G. L., Krakowka, S., Hoover, E. A., Olsen, R. G. and Yohn, D. S. 1976. Characterization of feline T-and B-lymphocytes and identification of an experimentally induced T-cell neoplasm in the cat. J. Natl. Cancer Inst. 57: 907-913.
8. Crandell, R. A., Fabricant, C. G. and Nelson-Rees, W. A. 1973. Development, characterization, and viral susceptibility of a feline (Felis catus) renal cell line (CRFK). In Vitro 9: 176-185.
9. Feng, J., Funk, W. D., Wang, S. S., Weinrich, S. L., Avilion, A. A., Chiu, C. P., Adams, R. R., Chang, E., Allsopp, R. C., Yu, J., Le, S., West, M. D., Harlay, C. B., Andrews, W. H., Greider, C. W. and Villeponteau, B. 1995. The RNA component of human telomerase. Science 269: 1236-1241.
10. Fletcher, T. M., Salazar, M. and Chen, S. F. 1996. Human telomerase inhibition by 7-deaza-2′-deoxypurine nucleoside triphosphates. Biochemistry 35: 15611-15617.
11. Greenberg, R. A., Allsopp, R. C., Chin, L., Morin, G. B. and DePinho, R. A. 1998. Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 16: 1723-1730.
12. Griffith, J. D., Comeau, L., Rosenfield, S., Stansel, R. M., Bianchi, A., Moss, H. and de Lange, T. 1999. Mammalian telomeres end in a large duplex loop. Cell 97: 503-514.
13. Guilford, W. G., Center, S. A., Strombeck, D. R., Williams, D. A. and Meyer, D. J. 1996. Strombeck's Small Animal Gastroenterology, 3rd ed., W. B. Saunders, Philadelphia.
14. Harley, C. B., Futcher, A. B. and Greider, C. W. 1990. Telomeres shorten during ageing of human fibroblasts. Nature (Lond.) 345: 458-460.
15. Hiyama, E. and Hiyama, K. 2002. Clinical utility of telomerase in cancer. Oncogene. 21: 643-649.
16. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L. and Shay, J. W. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015.
17. Kolquist, K. A., Ellisen, L. W., Counter, C. M., Meyerson, M., Tan, L. K., Weinberg, R. A., Haber, D. A. and Gerald, W. L. 1998. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat. Genet. 19: 182-186.
18. Lundblad, V. and Blackburn, E. H. 1993. An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell 73: 347-360.
19. Meyerson, M., Counter, C. M., Eaton, E. N., Ellisen, L. W., Steiner, P., Caddle, S. D., Ziaugra, L., Beijersbergen, R. L., Davidoff, M. J., Liu, Q., Bacchetti, S., Haber, D. A. and Weinberg, R. A. 1997. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90: 785-795.
20. Miura, T., Tsujimoto, H., Fukasawa, M., Kodama, T., Shibuya, M., Hasegawa, A. and Hayami, M. 1987. Structural abnormality and over-expression of the myc gene in feline leukemias. Int. J. Cancer 40: 564-569.
21. Morin, G. B. 1989. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59: 521-529.
22. Nakamura, T. M., Cooper, J. P. and Cech, T. R. 1998. Two modes of survival of fission yeast without telomerase. Science 282: 493-496.
23. Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B. and Cech, T. R. 1997. Telomerase catalytic subunit homologs from fission yeast and human. Science 277: 955-959.
24. Norton, J. C., Piatyszek, M. A., Wright, W. E., Shay, J. W. and Corey, D. R. 1996. Inhibition of human telomerase activity by peptide nucleic acids. Nat. Biotechnol. 14: 615-619.
25. Rojko, J. L., Kociba, G. J., Abkowitz, J. L., Hamilton, K. L., Hardy, W. D., Jr., Ihle, J. N. and O'Brien, S. J. 1989. Feline lymphomas: immunological and cytochemical characterization. Cancer Res. 49: 345-351.
26. Shay, J. W. and Bacchetti, S. 1997. A survey of telomerase activity in human cancer. Eur. J. Cancer 33: 787-791.
27. Strahl, C. and Blackburn, E. H. 1996. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol. Cell Biol. 16: 53-65.
28. Yazawa, M., Okuda, M., Setoguchi, A., Iwabuchi, S., Nishimura, R., Sasaki, N., Masuda, K., Ohno, K. and Tsujimoto, H. 2001. Telomere length and telomerase activity in canine mammary gland tumors. Am. J. Vet. Res. 62: 1539-1543.
29. Yazawa, M., Okuda, M., Setoguchi, A., Nishimura, R., Sasaki, N., Hasegawa, A., Watari, T. and Tsujimoto, H. 1999. Measurement of telomerase activity in dog tumors. J. Vet. Med. Sci. 61: 1125-1129.
30. Zakian, V. A. 1995. Telomeres: beginning to understand the end. Science 270: 1601-1607.