Endostatin causes G 1 arrest of endothelial cells through inhibition of cyclin D1

Journal of Biological Chemistry

Volumn 277, Issue 19, 2002, Pages 16464-16469

  Hanai, Jun Ichi ^a   Dhanabal, Mohan ^b   Ananth Karumanchi, S ^c   Albanese, Chris ^d   Waterman, Matthew ^e   Chan, Barden ^a,b   Ramchandran, Ramani ^c,d   Pestell, Richard ^a   Sukhatme, Vikas P ^a,f  

^a Center for Study of the Tumor Microenvironment   (Israel)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d CURAGEN CORPORATION   (United States)

^e EASTERN NAZARENE COLLEGE   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS;

COLLAGEN; ENZYME INHIBITION; GENES; RNA;

CELLS;

BETA CATENIN; CYCLIN D1; ENDOSTATIN; GENE PRODUCT; MESSENGER RNA; ANGIOGENESIS INHIBITOR; COLLAGEN; COLLAGEN TYPE 18; COMPLEMENTARY DNA; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; LEF1 PROTEIN, HUMAN; LYMPHOID ENHANCER FACTOR 1; PEPTIDE FRAGMENT; RETINOBLASTOMA PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL MIGRATION; CONTROLLED STUDY; DELETION MUTANT; DOWN REGULATION; ENDOTHELIUM CELL; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; TUMOR SUPPRESSOR GENE; BINDING SITE; CELL CULTURE; CELL CYCLE; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENE DELETION; GENETIC TRANSFECTION; METABOLISM; MUTATION; PROTEIN BINDING; RETROVIRUS; TIME; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ANIMALIA;

ANGIOGENESIS INHIBITORS; BETA CATENIN; BINDING SITES; CELL CYCLE; CELLS, CULTURED; COLLAGEN; COLLAGEN TYPE XVIII; CYCLIN D1; CYTOSKELETAL PROTEINS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOSTATINS; ENDOTHELIUM, VASCULAR; G1 PHASE; GENE DELETION; HUMANS; LYMPHOID ENHANCER-BINDING FACTOR 1; MUTATION; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RETINOBLASTOMA PROTEIN; RETROVIRIDAE; RNA, MESSENGER; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; UMBILICAL VEINS;

EID: 0037052336     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M112274200     Document Type: Article

References (29)