Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma

American Journal of Pathology

Volumn 148, Issue 4, 1996, Pages 1065-1074

  Brown, Lawrence F ^a   Tognazzi, Kathi ^a   Dvorak, Harold F ^a   Harrist, Terence J ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANGIOGENESIS; ANGIOSARCOMA; ARTICLE; BLOOD VESSEL PERMEABILITY; CAPILLARY HEMANGIOMA; CELL GROWTH; EDEMA; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; KAPOSI SARCOMA; PRIORITY JOURNAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; CAPILLARY PERMEABILITY; ENDOTHELIAL GROWTH FACTORS; HEMANGIOMA, CAPILLARY; HEMANGIOSARCOMA; HUMANS; LYMPHOKINES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SARCOMA, KAPOSI; SKIN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0029993747     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Enzinger FM, Weiss SW Soft Tissue Tumors, ed 3 St Louis, MO, Mosby, 1995, 658-676
2. Naidu YM, Rosen EM, Zitnick R, Goldberg I, Park M, Naujokas M, Polverini PJ, Nickoloff BJ Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma. Proc Natl Acad Sci USA 1994, 91.5281-5285
3. Dvorak HF, Orenstein NS, Carvalho AC, Churchill WH, Dvorak AM, Galli SJ, Feder J, Bitzer AM, Rypysc J, Giovinco P: Induction of a fibrin-gel investment an early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products J Immunol 1979, 122:166-174
4. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983, 219:983-985
5. Keck PJ, Hauser SD, Krivi G, Sanzo K, Warren T, Feder J, Connolly DT: Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989, 246:1309-1312
6. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen Science 1989, 246:1306-1309
7. Gospodarowicz D, Abraham JA, Schilling J: Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells. Proc Nat Acad Sci USA 1989, 86:7311-7315
8. Ferrara N, Henzel WJ: Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun, 1989, 161:851-858
9. 2+ and von Willebrand factor release in human endothelial cells Am J Pathol 1991, 138:213-221
10. Pepper MS, Ferrara N, Orci L, Montesano R: Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991, 181.902-906
11. Unemori EN, Ferrara N, Bauer EA, Amento EP Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol 1992, 153 557-562
12. Clauss M, Gerlach M, Gerlach H, Brett J, Wang F, Familletti PC, Pan Y-CE, Olander JV, Connolly DT, Stern D: Vascular permeability factor, a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990, 172.1535-1545
13. de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor Science 1992, 255. 989-991
14. Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Bohlen P. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 1992, 187:1579-1586
15. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Dvorak HF, Senger DR Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas Am J Pathol 1993, 143:1255-1262
16. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Senger DR, Dvorak HF: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 1993, 53:4727-4735
17. Dvorak HF, Sioussat TM, Brown LF, Berse B, Nagy JA, Sotrel A, Manseau EJ, Van De Water L, Senger DR Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J Exp Med 1991, 174 1275-1278
18. Plate KH, Breier G, Weich HA, Risau W: Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992, 359. 845-848
19. Senger DR, Perruzzi CA, Feder J, Dvorak HF: A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 1986, 46:5629-5632
20. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 1992, 359:843-845
21. Berse B, Brown LF, Van De Water L, Dvorak HF, Senger DR. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 1992, 3:211-220
22. Kim KJ, Li B, Winer J, Armanini M, Gillet N, Phillips HS, Ferrara N: Inhibition of vascular endothelial growth factor induced angiogenesis suppresses tumor growth in vivo Nature 1993, 362:841-844
23. Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A: Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 1994, 367:576-579
24. Fava RA, Olsen NJ, Spencer-Green G, Yeo KT, Berse B, Jackman RJ, Senger DR, Dvorak HF, Brown LF: Vascular permeability factor/endothelial growth factor (VPF/VEGF) accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med 1994, 180.341-346
25. Koch AE, Harlow LA, Haines GK, Amento EP, Unemori EN, Wong WL, Pope RM, Ferrara N. Vascular endothelial growth factor A cytokine modulating endothelial function in rheumatoid arthritis J Immunol 1994, 152. 4149-4156
26. Brown LF, Yeo K-T, Berse B, Yeo T-K, Senger DR, Dvorak HF, Van De Water L: Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing J Exp Med 1992, 176.1375-1379
27. Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW, Berse B, Dvorak HF: Overexpression of vascular permeability factor and its receptors in psoriasis J Exp Med 1994, 180:1141-1146
28. Brown LF, Olbricht SM, Berse B, Jackman RW, Matsueda G, Manseau EJ, Dvorak HF, Van De Water L: Expression of vascular permeability factor in delayed hypersensitivity skin reactions. J Immunol 1995, 154. 2801-2807
29. Brown LF, Harrist TJ, Yeo KT, Stahle-Backdahl M, Jackman RW, Berse B, Tognazzi K, Dvorak HF, Detmar M Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme J Invest Dermatol 1995, 104:744-749
30. Weindel K, Marme D, Weich HA: AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun 1992, 183:1167-1174
31. Takahashi K, Mulliken JB, Kozakewich HP, Rogers RA, Folkman J, Esekowitz RA: Cellular markers that distinguish the phases of hemangioma during infancy and childhood. J Clin Invest 1994, 93:2357-2364
32. Morii K, Tanaka R, Washiyama K, Kumanishi T, Kuwano R. Expression of vascular endothelial growth factor in capillary hemangioblastoma. Biochem Biophys Res Commun 1993, 194:749-755
33. ffrench-Constant C, Van De Water L, Dvorak HF, Hynes RO. Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J Cell Biol 1989, 109:903-914
34. Brown LF, Berse B, Tognazzi K, Manseau EJ, Van De Water L, Senger D, Dvorak H, Rosen S: Vascular permeability factor mRNA and protein expression in human kidney Kidney Int 1992, 42:1457-1461
35. Sioussat TM, Dvorak HF, Brock TA, Senger DR Inhibition of vascular permeability factor (vascular endothelial growth factor) with anti-peptide antibodies Arch Biochem Biophys 1993, 301 15-20
36. Li JJ, Huang YQ, Moscatelli D, Nicolaides A, Zhang WC, Freidman-Klein AE: Expression of fibroblast growth factors and their receptors in acquired immunodeficiency syndrome-associated Kaposi's sarcoma tissue and derived cells Cancer 1993, 72:2253-2259
37. Werner S, Hofschneider PH, Heldin CH, Ostman A, Roth WK: Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors Exp Cell Res 1990, 187:98-103
38. Sturzl M, Roth WK, Brockmeyer NH, Zeitz C, Speiser B, Hofschneider PH Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi's sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance. Proc Natl Acad Sci USA 1992, 89:7046-7050
39. Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F, Gallo RC. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine, and paracrine growth effects Science 1989, 243 223-226
40. Xerri L, Hassoun J, Planche J, Guigou V, Grob JJ. Parc P, Birnbaum D, deLapeyriere O. Fibroblast growth factor gene expression in AIDS-Kaposi's sarcoma detected by in situ hybridization Am J Pathol 1991, 138 9-15
41. Miles SA, Rezai AR, Salazar-Gonzales JF, Vander Meyden M, Stevens RH, Logan DM, Mitsuyasu RT, Taga T, Hirano T, Kishimoto T, Martinez-Maza O AIDS Kaposi sarcoma-derived cells produce and respond to interleukin-6. Proc Natl Acad Sci USA 1990, 87:4068-4072
42. Ladoux A, Frelin C: Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart Biochem Biophys Res Commun 1993, 195 1005-1010
43. Goldberg MA, Schneider TJ. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor, and erythropoietin. J Biol Chem 1994, 269.4355-4359
44. Brown LF, Berse B, Jackman RW, Tognazzi K, Guidi AJ, Dvorak HF, Senger DR, Connolly JL, Schnitt SJ. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 1995, 26 86-91
45. Dolecki GJ, Connolly DT. Effects of a variety of cytokines and inducing agents on vascular permeability factor mRNA levels in U937 cells. Biochem Biophys Res Commun 1991, 180:572-578
46. Brogi E, Wu T, Namiki A, Isner JM Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 1994, 90: 649-652
47. Finkenzeller G, Marme D, Weich HA, Hug H: Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C Cancer Res 1992, 52:4821-4823
48. Pertovaara L, Kaipainen A, Mustonen T, Orpana A, Ferrara N, Saksela O, Ahtalo K. Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells J Biol Chem 1994, 269:6271-6274
49. Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang HK, Brady JN, Gallo RC: Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma. Nature 1994, 371 674-680
50. Ensoli B, Markham P, Kao V, Barillari G, Fiorelli V, Gendelman R, Raffeld M, Zon G, Gallo RC: Block of AIDS-associated Kaposi's sarcoma cell growth, angiogenesis, and lesion formation in nude mice by anti-sense oligonucleotide targeting basic fibroblast growth factor A novel strategy for the therapy of KS. J Clin Invest 1994, 94:1736-1746