Thermodynamic basis of the enhanced specificity of structured DNA probes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 11, 1999, Pages 6171-6176

  Bonnet, Grégoire ^a   Tyagi, Sanjay ^b   Libchaber, Albert ^a   Kramer, Fred Russell ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

Fluorescence quenching; Mismatch discrimination; Molecular beacons; Molecular recognition; Phase diagram

Indexed keywords

ARTICLE; BASE PAIRING; CONFORMATIONAL TRANSITION; DNA BINDING; DNA CONFORMATION; DNA PROBE; FLUORESCENCE; MOLECULAR RECOGNITION; PHASE TRANSITION; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; THERMODYNAMICS;

BASE SEQUENCE; DNA PROBES; FLUORESCEINS; HEAT; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; SOLUTIONS; THERMODYNAMICS;

EID: 0033033430     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.11.6171     Document Type: Article

References (20)

1. Tyagi, S. & Kramer, F. R. (1996) Nat. Biotechnol. 14, 303-308.
2. Abou-ela, F., Koh, D., Tinoco, I., Jr., & Martin, F. H. (1985) Nucleic Acids Res. 13, 4811-4824.
3. Wagner, R., Debbie, P. & Radman, M. (1995) Nucleic Acids Res. 23, 3944-3948.
4. Youil, R., Kemper, B. W. & Cotton, R. G. H. (1995) Proc. Natl. Acad. Sci. USA 92, 87-91.
5. Nelson, N. C., Hammond, P. W., Matsuda, E., Goud A. A. & Becker, M. M. (1996) Nucleic Acids Res. 24, 4998-5003.
6. Cantor, C. R. & Shimmel, P. R. (1980) Biophysical Chemistry: The Behavior of Biological Macromolecules, Part III (Freeman, San Francisco), pp. 1109-1264.
7. Tyagi, S., Bratu, D. P. & Kramer, F. R. (1998) Nat. Biotechnol. 16, 49-53.
8. Marras, S. A. E., Kramer, F. R. & Tyagi, S. (1999) Genet. Anal. 14, 151-156.
9. Morrison, L. E. & Stols, L. M. (1993) Biochemistry 32, 3095-3104.
10. Mergny, J. L., Boutorine, S. A., Garestier, T., Belloc, F., Rougee, M., Bulychev, N. V., Koshkin, A. A., Bourson, J., Lebedev, A., Valeur, B., Thuong, N. T. & Helene, C. (1994) Nucleic Acids Res. 22, 920-928.
11. Parkhurst, K. M. & Parkhurst, L. J. (1995) Biochemistry 34, 285-292.
12. Tibanyenda, N., De Bruin, S. H., Hassnoot, C. A. G., van der Marel, G. A., van Boom, J. H. & Hilbers, C. W. (1984) Eur. J. Biochem. 139, 19-27.
13. Werntges, H., Steger, G., Riesner, D. & Fritz, H.-J. (1986) Nucleic Acids Res. 14, 3773-3790.
14. Ikuta, S., Takagi, K., Wallace, R. B. & Itakura, K. (1987) Nucleic Acids Res. 15, 797-811.
15. Wang, S., Friedman, A. E. & Kool, E. T. (1995) Biochemistry 34, 9784-9794.
16. Roberts, R. W. & Crothers, D. M. (1991) Proc. Natl. Acad. Sci. USA 88, 9397-9401.
17. Yoon, K., Turner, D. H. & Tinoco, I., Jr. (1975) J. Mol. Biol. 99, 507-518.
18. Topal, M. D. & Fresco, J. R. (1976) Nature (London) 263, 289-293.
19. Ouyang, Q., Kaplan, P. D., Liu, S. & Libchaber, A. (1997) Science 278, 446-449.
20. Monia, B. P., Johnston, J. F., Ecker, D. J., Zounes, M. A., Lima, W. F. & Freier, S. M. (1992) J. Biol. Chem. 267, 19954-19962.