Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis

New England Journal of Medicine

Volumn 347, Issue 6, 2002, Pages 408-415

  Herbrecht, Raoul ^a,q,r   Denning, David W ^b,c   Patterson, Thomas F ^d   Bennett, John E ^e   Greene, Reginald E ^f,g   Oestmann, Jörg W ^k   Kern, Winfried V ^b,f,q   Marr, Kieren A ^h   Ribaud, Patricia ⁱ   Lortholary, Olivier ^j   Sylvester, Richard ^j   Rubin, Robert H ^k   Wingard, John R ^l   Stark, Paul ^m   Durand, Christine ⁿ   Caillot, Denis ^o   Thiel, Eckhard ^f   Chandrasekar, Pranatharthi H ^p   Hodges, Michael R ^q   Schlamm, Haran T ^r   Troke, Peter F ^s   De Pauw, Ben ^e   more..

^a HÔPITAL DE HAUTEPIERRE   (France)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g UNIVERSITY OF FREIBURG   (Germany)

^h Fred Hutchinson Cancer Research Center   (United States)

ⁱ SAINT LOUIS HOSPITAL   (France)

^j INSTITUT PASTEUR   (France)

^k EORTC DATA CENTER   (Belgium)

^l BRIGHAM AND WOMEN S HOSPITAL   (United States)

^m UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o HÔPITAL DU BOCAGE   (France)

^p WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^r Sandwich United Kingdom   (Netherlands)

^s RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; VORICONAZOLE;

ACUTE LEUKEMIA; ADOLESCENT; ADULT; AGED; ALLOGRAFT; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLOSIS; BODY WEIGHT; CELL INVASION; CELL TRANSPLANTATION; CHILL; CLINICAL TRIAL; COLOR VISION DEFECT; CONFIDENCE INTERVAL; CONFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FEVER; HALLUCINATION; HEMATOPOIETIC CELL; HUMAN; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NEPHROTOXICITY; OUTCOMES RESEARCH; PHOTOPHOBIA; PHOTOSENSITIVITY; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; VISUAL DISORDER; VISUAL IMPAIRMENT;

ADOLESCENT; ADULT; AGED; AMPHOTERICIN B; ANTIFUNGAL AGENTS; ASPERGILLOSIS; FEMALE; HEMATOLOGIC DISEASES; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PYRIMIDINES; SURVIVAL RATE; TRIAZOLES;

EID: 0037043655     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa020191     Document Type: Article

References (13)

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4. Clinical significance of nephrotoxicity in patients treated with amphotericin B for suspected or proven aspergillosis
5. Mortality and costs of acute renal failure associated with amphotericin B therapy
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7. In vitro fungicidal activities of voriconazole, itraconazole, and amphotericin B against opportunistic moniliaceous and dematiaceous fungi
8. Efficacy and safety ofvoriconazole in the treatment of acute invasive aspergillosis
9. Invasive pulmonary aspergillosis in acute leukemia: Characteristic findings on CT, the CT halo sign, and the role of CT in early diagnosis
10. On the use of Pocock and Simon's method for balancing treatment numbers over prognostic factors in the controlled clinical trial
11. An EORTC international multicenter randomized trial (EORTC number 19923) comparing two dosages of liposomal amphotericin B for treatment of invasive aspergillosis
12. Amphotericin B colloidal dispersion vs. amphotericin B as therapy for invasive aspergillosis
13. Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever