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Volumn 3, Issue 3, 2003, Pages 477-486

Therapeutic vaccination for the treatment of mucosotropic human papillomavirus-associated disease

Author keywords

Fusion proteins; Genital warts; Heat shock proteins; Hsp65; Human papillomavirus; Immunity; Immunotherapeutic; Papillomavirus; Vaccine

Indexed keywords

ADJUVANT; COVAL; CYTOTOXIC AGENT; HEAT SHOCK PROTEIN; HEPATITIS B CORE ANTIGEN; HPV16 E7 VACCINE; HUMAN PAPILLOMA VIRUS ANTIGEN; HYBRID PROTEIN; IMIQUIMOD; NUCLEOPROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VACCINE; VIRUS ANTIGEN; WART VIRUS VACCINE;

EID: 0037526586     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.3.3.477     Document Type: Review
Times cited : (21)

References (107)
  • 1
    • 0034600355 scopus 로고    scopus 로고
    • Papillomaviruses causing cancer: Evasion from host-cell control in early events in carcinogenesis
    • ZUR HAUSEN H: Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J. Natl. Cancer Inst. (2000) 92:690-698.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 690-698
    • Zur Hausen, H.1
  • 2
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections - A major cause of human cancers
    • ZUR HAUSEN H: Papillomavirus infections-a major cause of human cancers. Biochim. Biophys. Acta. (1996) 1288:F55-F78.
    • (1996) Biochim. Biophys. Acta , vol.1288
    • Zur Hausen, H.1
  • 3
    • 0029881833 scopus 로고    scopus 로고
    • Human papillomavirus - The most significant risk determinant of cervical intraepithelial neoplasia
    • KJAER SK, VAN DEN BRULE AJ, BOCK JE et al.: Human papillomavirus-the most significant risk determinant of cervical intraepithelial neoplasia. Int. J. Cancer (1996) 65:601-606.
    • (1996) Int. J. Cancer , vol.65 , pp. 601-606
    • Kjaer, S.K.1    Van Den Brule, A.J.2    Bock, J.E.3
  • 4
    • 0029041842 scopus 로고
    • Prevalence of human papillomavirus in cervical cancer: A worldwide perspective
    • International Biological Study on Cervical Cancer (IBSCC) Study Group
    • BOSCH FX, MANOS MM, MUNOZ N et al.: Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International Biological Study on Cervical Cancer (IBSCC) Study Group. J. Natl. Cancer Inst. (1995) 87:796-802.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 796-802
    • Bosch, F.X.1    Manos, M.M.2    Munoz, N.3
  • 5
    • 0036221471 scopus 로고    scopus 로고
    • The causal relation between human papillomavirus and cervical cancer
    • BOSCH FX, LORINCZ A, MUNOZ N, MEIJER CJ, SHAH KV: The causal relation between human papillomavirus and cervical cancer. J. Clin. Pathol. (2002) 55:244-265. A definitive argument for citing high-risk HPV as a necessary cause of cervical cancer.
    • (2002) J. Clin. Pathol. , vol.55 , pp. 244-265
    • Bosch, F.X.1    Lorincz, A.2    Munoz, N.3    Meijer, C.J.4    Shah, K.V.5
  • 6
    • 0030693377 scopus 로고    scopus 로고
    • Sexually transmitted infection as a cause of anal cancer
    • FRISCH M, GLIMELIUS B, VAN DEN BRULE AJ et al.: Sexually transmitted infection as a cause of anal cancer. N. Engl. J. Med. (1997) 337:1350-1358.
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1350-1358
    • Frisch, M.1    Glimelius, B.2    Van Den Brule, A.J.3
  • 7
    • 0030875094 scopus 로고    scopus 로고
    • Distinct manifestations of human papillomaviruses in the vagina
    • SUGASE M, MATSUKURA T: Distinct manifestations of human papillomaviruses in the vagina. Int. J. Cancer (1997) 72:412-415.
    • (1997) Int. J. Cancer , vol.72 , pp. 412-415
    • Sugase, M.1    Matsukura, T.2
  • 8
    • 0035879829 scopus 로고    scopus 로고
    • Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas
    • VAN HOUTEN VM, SNIJDERS PJ, VAN DEN BREKEL MW et al.: Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas. Int. J. Cancer (2001) 93:232-235.
    • (2001) Int. J. Cancer , vol.93 , pp. 232-235
    • Van Houten, V.M.1    Snijders, P.J.2    Van Den Brekel, M.W.3
  • 9
    • 0032833740 scopus 로고    scopus 로고
    • Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients
    • BROWN DR, SCHROEDER JM, BRYAN JT, STOLER MH, FIFE KH: Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients. J. Clin. Microbiol. (1999) 37:3316-3322.
    • (1999) J. Clin. Microbiol. , vol.37 , pp. 3316-3322
    • Brown, D.R.1    Schroeder, J.M.2    Bryan, J.T.3    Stoler, M.H.4    Fife, K.H.5
  • 11
    • 0036523573 scopus 로고    scopus 로고
    • Therapy for recurrent respiratory papillomatosis
    • AUBORN KJ: Therapy for recurrent respiratory papillomatosis. Antiviral Ther. (2002) 7:1-9.
    • (2002) Antiviral Ther. , vol.7 , pp. 1-9
    • Auborn, K.J.1
  • 12
    • 0031554094 scopus 로고    scopus 로고
    • Epidemiology of genital human papillomavirus infection
    • KOUTSKY L: Epidemiology of genital human papillomavirus infection. Am. J. Med. (1997) 102:3-8.
    • (1997) Am. J. Med. , vol.102 , pp. 3-8
    • Koutsky, L.1
  • 13
    • 0032510076 scopus 로고    scopus 로고
    • Natural history of cervicovaginal papillomavirus infection in young women
    • HO GY, BIERMAN R, BEARDSLEY L, CHANG CJ, BURK RD: Natural history of cervicovaginal papillomavirus infection in young women. N. Engl. J. Med. (1998) 338:423-428.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 423-428
    • Ho, G.Y.1    Bierman, R.2    Beardsley, L.3    Chang, C.J.4    Burk, R.D.5
  • 14
    • 0029147763 scopus 로고
    • Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia
    • HO GY, BURK RD, KLEIN S et al.: Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia. J. Natl. Cancer Inst. (1995) 87:1365-1371.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1365-1371
    • Ho, G.Y.1    Burk, R.D.2    Klein, S.3
  • 15
    • 0029921786 scopus 로고    scopus 로고
    • Spontaneous evolution of intraepithelial lesions according to the grade and type of the implicated human papillomavirus (HPV)
    • SYRJANEN KJ: Spontaneous evolution of intraepithelial lesions according to the grade and type of the implicated human papillomavirus (HPV). Eur. J. Obstet. Gynecol. Reprod. Biol. (1996) 65:45-53.
    • (1996) Eur. J. Obstet. Gynecol. Reprod. Biol. , vol.65 , pp. 45-53
    • Syrjanen, K.J.1
  • 16
    • 0031892225 scopus 로고    scopus 로고
    • Anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual and bisexual men: Prevalence and risk factors
    • PALEFSKY JM, HOLLY EA, RALSTON ML et al.: Anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual and bisexual men: prevalence and risk factors. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. (1998) 17:320-326.
    • (1998) J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. , vol.17 , pp. 320-326
    • Palefsky, J.M.1    Holly, E.A.2    Ralston, M.L.3
  • 18
    • 0035149837 scopus 로고    scopus 로고
    • Cervical cancer vaccines: Emerging concepts and developments
    • DA SILVA DM, EIBEN GL, FAUSCH SC et al.: Cervical cancer vaccines: emerging concepts and developments. J. Cell Physiol. (2001) 186:169-182. Thorough review of the HPV vaccine field.
    • (2001) J. Cell Physiol. , vol.186 , pp. 169-182
    • Da Silva, D.M.1    Eiben, G.L.2    Fausch, S.C.3
  • 19
  • 21
    • 0037153042 scopus 로고    scopus 로고
    • A controlled trial of a human papillomavirus Type 16 vaccine
    • KOUTSKY LA, AULT KA, WHEELER CM et al.: A controlled trial of a human papillomavirus Type 16 vaccine. N. Engl. J. Med. (2002) 347:1645-1651.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1645-1651
    • Koutsky, L.A.1    Ault, K.A.2    Wheeler, C.M.3
  • 22
    • 0030893225 scopus 로고    scopus 로고
    • Invasive cervical cancer after conservative therapy for cervical intraepithelial neoplasia
    • SOUTTER WP, DE BARROS LOPES A, FLETCHER A et al.: Invasive cervical cancer after conservative therapy for cervical intraepithelial neoplasia. Lancet (1997) 349:978-980.
    • (1997) Lancet , vol.349 , pp. 978-980
    • Soutter, W.P.1    De Barros Lopes, A.2    Fletcher, A.3
  • 23
    • 0032125237 scopus 로고    scopus 로고
    • Cytology and colposcopy after loop electrosurgical excision: Implications for follow-up
    • BALDAUF JJ, DREYFUS M, RITTER J, CUENIN C, TISSIER I, MEYER P: Cytology and colposcopy after loop electrosurgical excision: implications for follow-up. Obstet. Gynecol. (1998) 92:124-130.
    • (1998) Obstet. Gynecol. , vol.92 , pp. 124-130
    • Baldauf, J.J.1    Dreyfus, M.2    Ritter, J.3    Cuenin, C.4    Tissier, I.5    Meyer, P.6
  • 25
    • 0034750307 scopus 로고    scopus 로고
    • The treatment of human papillomavirus lesions of the lower genital tract Best Pract
    • SONNEX C, LACEY CJ: The treatment of human papillomavirus lesions of the lower genital tract Best Pract. Res. Clin. Obstet. Gynaecol. (2001) 15:801-816.
    • (2001) Res. Clin. Obstet. Gynaecol. , vol.15 , pp. 801-816
    • Sonnex, C.1    Lacey, C.J.2
  • 26
    • 0033823434 scopus 로고    scopus 로고
    • Immune-response modifiers: A new paradigm in the treatment of Human Papillomavirus
    • TYRING SK: Immune-response modifiers: a new paradigm in the treatment of Human Papillomavirus. Curr. Ther. Res. Clin. Exp. (2000) 61:584-596.
    • (2000) Curr. Ther. Res. Clin. Exp. , vol.61 , pp. 584-596
    • Tyring, S.K.1
  • 27
    • 0035085156 scopus 로고    scopus 로고
    • Treatment of external genital warts in men using 5% imiquimod cream applied three times a week, once daily, twice daily, or three times a day
    • FIFE KH, FERENCZY A, DOUGLAS JM JR, BROWN DR, SMITH M, OWENS ML: Treatment of external genital warts in men using 5% imiquimod cream applied three times a week, once daily, twice daily, or three times a day. Sex. Transm. Dis. (2001) 28:226-231.
    • (2001) Sex. Transm. Dis. , vol.28 , pp. 226-231
    • Fife, K.H.1    Ferenczy, A.2    Douglas J.M., Jr.3    Brown, D.R.4    Smith, M.5    Owens, M.L.6
  • 28
    • 0031554081 scopus 로고    scopus 로고
    • Therapeutic approaches to genital warts
    • BEUTNER KR, FERENCZY A: Therapeutic approaches to genital warts. Am. J. Med. (1997) 102:28-37.
    • (1997) Am. J. Med. , vol.102 , pp. 28-37
    • Beutner, K.R.1    Ferenczy, A.2
  • 29
    • 0028910218 scopus 로고
    • Human papillomaviruses and cervical neoplasia. II. Interaction of HPV with other factors
    • HERRINGTON CS: Human papillomaviruses and cervical neoplasia. II. Interaction of HPV with other factors. J. Clin. Pathol. (1995) 48:1-6.
    • (1995) J. Clin. Pathol. , vol.48 , pp. 1-6
    • Herrington, C.S.1
  • 30
    • 0028934786 scopus 로고
    • Pathology of human papillomavirus in the female genital tract
    • MCLACHLIN CM: Pathology of human papillomavirus in the female genital tract. Curr. Opin. Obstet. Gynecol. (1995) 7:24-29.
    • (1995) Curr. Opin. Obstet. Gynecol. , vol.7 , pp. 24-29
    • Mclachlin, C.M.1
  • 31
    • 0028559782 scopus 로고
    • Immunological events in regressing genital warts
    • COLEMAN N, BIRLEY HD, RENTON AM et al.: Immunological events in regressing genital warts. Am. J. Clin. Pathol. (1994) 102:768-774.
    • (1994) Am. J. Clin. Pathol. , vol.102 , pp. 768-774
    • Coleman, N.1    Birley, H.D.2    Renton, A.M.3
  • 32
    • 0035946296 scopus 로고    scopus 로고
    • Regression of canine oral papillomas is associated with infiltration of CD4+ and CD8+ lymphocytes
    • NICHOLLS PK, MOORE PF, ANDERSON DM et al.: Regression of canine oral papillomas is associated with infiltration of CD4+ and CD8+ lymphocytes. Virology (2001) 283:31-39.
    • (2001) Virology , vol.283 , pp. 31-39
    • Nicholls, P.K.1    Moore, P.F.2    Anderson, D.M.3
  • 33
    • 0030942670 scopus 로고    scopus 로고
    • The rabbit viral skin papillomas and carcinomas: A model for the immunogenetics of HPV-associated carcinogenesis
    • BREITBURD F, SALMON J, ORTH G: The rabbit viral skin papillomas and carcinomas: a model for the immunogenetics of HPV-associated carcinogenesis. Clin. Dermatol. (1997) 15:237-247.
    • (1997) Clin. Dermatol. , vol.15 , pp. 237-247
    • Breitburd, F.1    Salmon, J.2    Orth, G.3
  • 34
    • 0344269308 scopus 로고    scopus 로고
    • Human papillomaviruses and associated malignancies
    • ALANI RM, MUNGER K: Human papillomaviruses and associated malignancies. J. Clin. Oncol. (1998) 16:330-337.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 330-337
    • Alani, R.M.1    Munger, K.2
  • 36
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus Type 16-transformed cells
    • FELTKAMP MC, SMITS HL, VIERBOOM MP et al.: Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus Type 16-transformed cells. Eur. J. Immunol. (1993) 23:2242-2249. Key paper describing the use of an E7 peptide epitope as an immunoprophylactic agent.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3
  • 37
    • 0030068375 scopus 로고    scopus 로고
    • Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen
    • LIN KY, GUARNIERI FG, STAVELEY-O'CARROLL KF et al.: Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Res. (1996) 56:21-26. Key paper demonstrating the utility of an E7 fusion construct as an immunotherapeutic agent.
    • (1996) Cancer Res. , vol.56 , pp. 21-26
    • Lin, K.Y.1    Guarnieri, F.G.2    Staveley-O'Carroll, K.F.3
  • 38
    • 0032519813 scopus 로고    scopus 로고
    • Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype
    • ZEHBE I, WILANDER E, DELIUS H, TOMMASINO M: Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype. Cancer Res. (1998) 58:829-833.
    • (1998) Cancer Res. , vol.58 , pp. 829-833
    • Zehbe, I.1    Wilander, E.2    Delius, H.3    Tommasino, M.4
  • 39
    • 0033052752 scopus 로고    scopus 로고
    • Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer
    • NINDL I, RINDFLEISCH K, LOTZ B, SCHNEIDER A, DURST M: Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer. Int. J. Cancer (1999) 82:203-207.
    • (1999) Int. J. Cancer , vol.82 , pp. 203-207
    • Nindl, I.1    Rindfleisch, K.2    Lotz, B.3    Schneider, A.4    Durst, M.5
  • 40
    • 0037081099 scopus 로고    scopus 로고
    • Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects
    • DE JONG A, VAN DER BURG SH, KWAPPENBERG KM et al.: Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects. Cancer Res. (2002) 62:472-479.
    • (2002) Cancer Res. , vol.62 , pp. 472-479
    • De Jong, A.1    Van Der Burg, S.H.2    Kwappenberg, K.M.3
  • 41
    • 0036849736 scopus 로고    scopus 로고
    • The status of HPV16-specific T-cell reactivity in health and disease as a guide to HPV vaccine development
    • VAN DER BURG SH, DE JONG A, WELTERS MJ, OFFRINGA R, MELIEF CJ: The status of HPV16-specific T-cell reactivity in health and disease as a guide to HPV vaccine development. Virus Res. (2002) 89:275-284. Concise review on issues facing HPV therapeutic vaccine field.
    • (2002) Virus Res. , vol.89 , pp. 275-284
    • Van Der Burg, S.H.1    De Jong, A.2    Welters, M.J.3    Offringa, R.4    Melief, C.J.5
  • 42
    • 0033061881 scopus 로고    scopus 로고
    • Potential strategies utilised by papillomavirus to evade host immunity
    • FRAZER IH, THOMAS R, ZHOU J et al.: Potential strategies utilised by papillomavirus to evade host immunity. Immunol. Rev. (1999) 168:131-142. Detailed explanation of HPV immune evasion strategies.
    • (1999) Immunol. Rev. , vol.168 , pp. 131-142
    • Frazer, I.H.1    Thomas, R.2    Zhou, J.3
  • 43
    • 0036364468 scopus 로고    scopus 로고
    • Immune evasion in human papillomavirus-associated cervical cancer
    • TINDLE RW: Immune evasion in human papillomavirus-associated cervical cancer. Nat. Rev. Cancer (2002) 2:59-65. See [42].
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 59-65
    • Tindle, R.W.1
  • 44
    • 0036548986 scopus 로고    scopus 로고
    • Spinning molecular immunology into successful immunotherapy
    • PARDOLL DM: Spinning molecular immunology into successful immunotherapy. Nat. Rev. Immunol. (2002) 2:227-238. Clear 'roadmap' for the variety of available immunotherapeutic strategies.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 227-238
    • Pardoll, D.M.1
  • 45
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • BANCHEREAU J, STEINMAN RM: Dendritic cells and the control of immunity. Nature (1998) 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 46
    • 0033061017 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte activation by cross-priming
    • HEATH WR, CARBONE FR: Cytotoxic T lymphocyte activation by cross-priming. Curr. Opin. Immunol. (1999) 11:314-318.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 314-318
    • Heath, W.R.1    Carbone, F.R.2
  • 47
    • 0034125081 scopus 로고    scopus 로고
    • Immunological concepts of vaccine adjuvant activity
    • SCHIJNS VE: Immunological concepts of vaccine adjuvant activity. Curr. Opin. Immunol. (2000) 12:456-463.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 456-463
    • Schijns, V.E.1
  • 48
    • 0036317963 scopus 로고    scopus 로고
    • Ubiquitin-fused and/or multiple early genes from cottontail rabbit papillomavirus as DNA vaccines
    • LEACHMAN SA, SHYLANKEVICH M, SLADE MD et al.: Ubiquitin-fused and/or multiple early genes from cottontail rabbit papillomavirus as DNA vaccines. J. Virol. (2002) 76:7616-7624.
    • (2002) J. Virol. , vol.76 , pp. 7616-7624
    • Leachman, S.A.1    Shylankevich, M.2    Slade, M.D.3
  • 49
    • 0028295047 scopus 로고
    • Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus Type 16 E6 and E7 proteins
    • KAST WM, BRANDT RM, SIDNEY J et al.: Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus Type 16 E6 and E7 proteins. J. Immunol. (1994) 152:3904-3912.
    • (1994) J. Immunol. , vol.152 , pp. 3904-3912
    • Kast, W.M.1    Brandt, R.M.2    Sidney, J.3
  • 50
    • 0029035637 scopus 로고
    • Human CTL epitopes encoded by human papillomavirus Type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides
    • RESSING ME, SETTE A, BRANDT RM et al.: Human CTL epitopes encoded by human papillomavirus Type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides. J. Immunol. (1995) 154:5934-5943.
    • (1995) J. Immunol. , vol.154 , pp. 5934-5943
    • Ressing, M.E.1    Sette, A.2    Brandt, R.M.3
  • 51
    • 0033153564 scopus 로고    scopus 로고
    • Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: Clinical evaluation of a Phase 141 trial
    • VAN DRIEL WJ, RESSING ME, KENTER GG et al.: Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a Phase 141 trial. Eur. J. Cancer (1999) 35:946-952.
    • (1999) Eur. J. Cancer , vol.35 , pp. 946-952
    • Van Driel, W.J.1    Ressing, M.E.2    Kenter, G.G.3
  • 52
    • 0036039310 scopus 로고    scopus 로고
    • Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus Type 16 E7 protein
    • STREET MD, DOAN T, HERD KA, TINDLE RW: Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus Type 16 E7 protein. Immunology (2002) 106:526-536.
    • (2002) Immunology. , vol.106 , pp. 526-536
    • Street, M.D.1    Doan, T.2    Herd, K.A.3    Tindle, R.W.4
  • 53
    • 0037107336 scopus 로고    scopus 로고
    • Establishment of an HLA-A*0201 human papillomavirus Type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice
    • EIBEN GL, VELDERS MP, SCHREIBER H et al.: Establishment of an HLA-A*0201 human papillomavirus Type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice. Cancer Res. (2002) 62:5792-5799. Improvement on E7-expressing transplantable tumour model.
    • (2002) Cancer Res. , vol.62 , pp. 5792-5799
    • Eiben, G.L.1    Velders, M.P.2    Schreiber, H.3
  • 54
    • 0029071711 scopus 로고
    • Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease
    • FRAZER IH, LEIPPE DM, DUNN LA et al.: Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease. Cancer Res. (1995) 55:2635-2639.
    • (1995) Cancer Res. , vol.55 , pp. 2635-2639
    • Frazer, I.H.1    Leippe, D.M.2    Dunn, L.A.3
  • 55
    • 0029864222 scopus 로고    scopus 로고
    • Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus Type 16 transgenic mice
    • ARBEIT JM, HOWLEY PM, HANAHAN D: Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus Type 16 transgenic mice. Proc. Natl. Acad Sci. USA (1996) 93:2930-2935.
    • (1996) Proc. Natl. Acad Sci. USA , vol.93 , pp. 2930-2935
    • Arbeit, J.M.1    Howley, P.M.2    Hanahan, D.3
  • 56
    • 0030899873 scopus 로고    scopus 로고
    • Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus Type 16
    • MELERO I, SINGHAL MC, MCGOWAN P et al.: Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus Type 16. J. Virol. (1997) 71:3998-4004.
    • (1997) J. Virol. , vol.71 , pp. 3998-4004
    • Melero, I.1    Singhal, M.C.2    Mcgowan, P.3
  • 57
    • 0031719384 scopus 로고    scopus 로고
    • Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes
    • FRAZER IH, FERNANDO GJ, FOWLER N et al.: Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes. Eur. J. Immunol. (1998) 28:2791-2800.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2791-2800
    • Frazer, I.H.1    Fernando, G.J.2    Fowler, N.3
  • 58
    • 0035575992 scopus 로고    scopus 로고
    • Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic proinflammatory signals at the time of first antigen exposure
    • FRAZER IH, DE KLUYVER R, LEGGATT GR et al.: Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic proinflammatory signals at the time of first antigen exposure. J. Immunol. (2001) 167:6180-6187. Highlights importance of pro-inflammatory signalling for inducing immunity.
    • (2001) J. Immunol. , vol.167 , pp. 6180-6187
    • Frazer, I.H.1    De Kluyver, R.2    Leggatt, G.R.3
  • 59
    • 0034212784 scopus 로고    scopus 로고
    • Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization
    • DOAN T, HERD KA, LAMBERT PF, FERNANDO GJ, STREET MD, TINDLE RW: Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization. Cancer Res. (2000) 60:2810-2815.
    • (2000) Cancer Res. , vol.60 , pp. 2810-2815
    • Doan, T.1    Herd, K.A.2    Lambert, P.F.3    Fernando, G.J.4    Street, M.D.5    Tindle, R.W.6
  • 60
    • 0035405173 scopus 로고    scopus 로고
    • Papillomavirus-like particle based vaccines: Cervical cancer and beyond
    • SCHILLER JT, LOWY DR: Papillomavirus-like particle based vaccines: cervical cancer and beyond. Expert Opin. Biol. Ther. (2001) 1:571-581.
    • (2001) Expert Opin. Biol. Ther. , vol.1 , pp. 571-581
    • Schiller, J.T.1    Lowy, D.R.2
  • 61
    • 0035340806 scopus 로고    scopus 로고
    • Papillomavirus-like particles induce acute activation of dendritic cells
    • LENZ P, DAY PM, PANG YY et al.: Papillomavirus-like particles induce acute activation of dendritic cells. J. Immunol. (2001) 166:5346-5355.
    • (2001) J. Immunol. , vol.166 , pp. 5346-5355
    • Lenz, P.1    Day, P.M.2    Pang, Y.Y.3
  • 62
    • 0032539564 scopus 로고    scopus 로고
    • Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model
    • GREENSTONE HL, NIELAND JD, DE VISSER KE et al.: Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc. Natl. Acad. Sci. USA (1998) 95:1800-1805.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1800-1805
    • Greenstone, H.L.1    Nieland, J.D.2    De Visser, K.E.3
  • 63
    • 0033135288 scopus 로고    scopus 로고
    • Chimeric papillomavirus virus-like particles induce a murine self-antigen-specific protective and therapeutic antitumor immune response
    • NIELAND JD, DA SILVA DM, VELDERS MP et al.: Chimeric papillomavirus virus-like particles induce a murine self-antigen-specific protective and therapeutic antitumor immune response. J. Cell Biochem. (1999) 73:145-152.
    • (1999) J. Cell Biochem. , vol.73 , pp. 145-152
    • Nieland, J.D.1    Da Silva, D.M.2    Velders, M.P.3
  • 64
    • 0036195860 scopus 로고    scopus 로고
    • Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
    • WILCOX RA, FLIES DB, ZHU G et al.: Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J. Clin. Invest. (2002) 109:651-659.
    • (2002) J. Clin. Invest. , vol.109 , pp. 651-659
    • Wilcox, R.A.1    Flies, D.B.2    Zhu, G.3
  • 65
    • 0036644556 scopus 로고    scopus 로고
    • Established human papillomavirus Type 16-expressing tumors are effectively eradicated following vaccination with long peptides
    • ZWAVELING S, FERREIRA MOTA SC, NOUTA J et al.: Established human papillomavirus Type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J. Immunol. (2002) 169:350-358. Emphasises benefit of enhancing APC function for immunotherapeutic effect.
    • (2002) J. Immunol. , vol.169 , pp. 350-358
    • Zwaveling, S.1    Ferreira Mota, S.C.2    Nouta, J.3
  • 66
    • 0028203840 scopus 로고
    • Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs
    • SHIRAI M, PENDLETON CD, AHLERS J, TAKESHITA T, NEWMAN M, BERZOFSKYJA: Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs. J. Immunol. (1994) 152:549-556.
    • (1994) J. Immunol. , vol.152 , pp. 549-556
    • Shirai, M.1    Pendleton, C.D.2    Ahlers, J.3    Takeshita, T.4    Newman, M.5    Berzofsky, J.A.6
  • 67
    • 0034788572 scopus 로고    scopus 로고
    • Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen
    • CHENG WF, HUNG CF, CHAI CY et al.: Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. J. Clin. Invest. (2001) 108:669-678.
    • (2001) J. Clin. Invest. , vol.108 , pp. 669-678
    • Cheng, W.F.1    Hung, C.F.2    Chai, C.Y.3
  • 68
    • 0033589811 scopus 로고    scopus 로고
    • Targeting human papillomavirus Type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus Type 16 E7-expressing tumors
    • JI H, WANG TL, CHEN CH et al.: Targeting human papillomavirus Type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus Type 16 E7-expressing tumors. Hum. Gene Ther. (1999) 10:2727-2740.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2727-2740
    • Ji, H.1    Wang, T.L.2    Chen, C.H.3
  • 69
    • 0036184794 scopus 로고    scopus 로고
    • Improving DNA vaccine potency by linking Marek's disease virus Type 1 VP22 to an antigen
    • HUNG CF, HE L, JUANG J, LIN TJ, LING M, WU TC: Improving DNA vaccine potency by linking Marek's disease virus Type 1 VP22 to an antigen. J. Virol. (2002) 76:2676-2682.
    • (2002) J. Virol. , vol.76 , pp. 2676-2682
    • Hung, C.F.1    He, L.2    Juang, J.3    Lin, T.J.4    Ling, M.5    Wu, T.C.6
  • 70
    • 0025382818 scopus 로고
    • The molecular chaperone concept
    • ELLIS RJ: The molecular chaperone concept. Semin. Cell Biol. (1990) 1:1-9.
    • (1990) Semin. Cell Biol. , vol.1 , pp. 1-9
    • Ellis, R.J.1
  • 71
    • 0031972072 scopus 로고    scopus 로고
    • Immune responses to stress proteins: Applications to infectious disease and cancer
    • MIZZEN L: Immune responses to stress proteins: applications to infectious disease and cancer. Biotherapy (1998) 10:173-189.
    • (1998) Biotherapy , vol.10 , pp. 173-189
    • Mizzen, L.1
  • 72
    • 0034652784 scopus 로고    scopus 로고
    • Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene
    • CHEN CH, WANG TL, HUNG CF et al.: Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res. (2000) 60:1035-1042.
    • (2000) Cancer Res. , vol.60 , pp. 1035-1042
    • Chen, C.H.1    Wang, T.L.2    Hung, C.F.3
  • 73
    • 0033994625 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus expressing human papillomavirus Type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer
    • LIU DW, TSAO YP, KUNG JT et al.: Recombinant adeno-associated virus expressing human papillomavirus Type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer. J. Virol. (2000) 74:2888-2894.
    • (2000) J. Virol. , vol.74 , pp. 2888-2894
    • Liu, D.W.1    Tsao, Y.P.2    Kung, J.T.3
  • 74
    • 0035077790 scopus 로고    scopus 로고
    • Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
    • HSU KF, HUNG CF, CHENG WF et al.: Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen. Gene Ther. (2001) 8:376-383.
    • (2001) Gene Ther. , vol.8 , pp. 376-383
    • Hsu, K.F.1    Hung, C.F.2    Cheng, W.F.3
  • 75
    • 0035873726 scopus 로고    scopus 로고
    • Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene
    • CHENG WF, HUNG CF, CHAI CY et al.: Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene. J. Immunol. (2001) 166:6218-6226. First demonstration of RNA vaccine technology combined with Hsp fusion construct.
    • (2001) J. Immunol. , vol.166 , pp. 6218-6226
    • Cheng, W.F.1    Hung, C.F.2    Chai, C.Y.3
  • 76
    • 0037135078 scopus 로고    scopus 로고
    • Tech.Sight. Gene therapy. Hurdles and hopes for cancer treatment
    • HUNT KK, VORBURGER SA: Tech. Sight. Gene therapy. Hurdles and hopes for cancer treatment. Science (2002) 297:415-416.
    • (2002) Science , vol.297 , pp. 415-416
    • Hunt, K.K.1    Vorburger, S.A.2
  • 77
    • 0345164329 scopus 로고    scopus 로고
    • Priming of CD8+ CTL effector cells in mice by immunization with a stress protein-influenza virus nudeoprotein fusion molecule
    • ANTHONY LS, WU H, SWEET H, TURNNIR C, BOUX LJ, MIZZEN LA: Priming of CD8+ CTL effector cells in mice by immunization with a stress protein-influenza virus nudeoprotein fusion molecule. Vaccine (1999) 17:373-383.
    • (1999) Vaccine , vol.17 , pp. 373-383
    • Anthony, L.S.1    Wu, H.2    Sweet, H.3    Turnnir, C.4    Boux, L.J.5    Mizzen, L.A.6
  • 78
    • 0033838826 scopus 로고    scopus 로고
    • Immunotherapy of a human papillomavirus (HPV) Type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7
    • CHU NR, WU HB, WU T, BOUX LJ, SIEGEL MI, MIZZEN LA: Immunotherapy of a human papillomavirus (HPV) Type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7. Clin. Exp. Immunol. (2000) 121:216-225. First demonstration of BCG Hsp65/ HPV16 E7 fusion protein having ability to induce cellular immunity and tumour regression.
    • (2000) Clin. Exp. Immunol. , vol.121 , pp. 216-225
    • Chu, N.R.1    Wu, H.B.2    Wu, T.3    Boux, L.J.4    Siegel, M.I.5    Mizzen, L.A.6
  • 79
    • 0033695064 scopus 로고    scopus 로고
    • A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins
    • CHO BK, PALLISER D, GUILLEN E et al.: A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins. Immunity (2000) 12:263-272.
    • (2000) Immunity , vol.12 , pp. 263-272
    • Cho, B.K.1    Palliser, D.2    Guillen, E.3
  • 80
    • 0030667939 scopus 로고    scopus 로고
    • Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway
    • SUZUE K, ZHOU X, EISEN HN, YOUNG RA: Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway. Proc. Natl. Acad. Sci. USA (1997) 94:13146-13151.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13146-13151
    • Suzue, K.1    Zhou, X.2    Eisen, H.N.3    Young, R.A.4
  • 81
    • 0035903158 scopus 로고    scopus 로고
    • Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
    • VABULAS RM, AHMAD-NEJAD P, DA COSTA C et al.: Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J. Biol. Chem. (2001) 276:31332-31339.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31332-31339
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    Da Costa, C.3
  • 82
    • 0036467447 scopus 로고    scopus 로고
    • Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
    • BULUT Y, FAURE E, THOMAS L et al.: Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. (2002) 168:1435-1440.
    • (2002) J. Immunol. , vol.168 , pp. 1435-1440
    • Bulut, Y.1    Faure, E.2    Thomas, L.3
  • 83
    • 0037080218 scopus 로고    scopus 로고
    • The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins
    • HABICH C, BAUMGART K, KOLB H, BURKART V: The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins. J. Immunol. (2002) 168:569-576.
    • (2002) J. Immunol. , vol.168 , pp. 569-576
    • Habich, C.1    Baumgart, K.2    Kolb, H.3    Burkart, V.4
  • 85
    • 0036644583 scopus 로고    scopus 로고
    • Heat-shock proteins as activators of the innate immune system
    • BAUSINGER H, LIPSKER D, HANAU D: Heat-shock proteins as activators of the innate immune system. Trends Immunol. (2002) 23:342-343.
    • (2002) Trends Immunol. , vol.23 , pp. 342-343
    • Bausinger, H.1    Lipsker, D.2    Hanau, D.3
  • 86
    • 0036179002 scopus 로고    scopus 로고
    • Heat shock proteins and innate immunity
    • GASTON JS: Heat shock proteins and innate immunity. Clin. Exp. Immunol. (2002) 127:1-3.
    • (2002) Clin. Exp. Immunol. , vol.127 , pp. 1-3
    • Gaston, J.S.1
  • 87
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
    • ASEA A, KRAEFT SK, KURT-JONES EA et al.: HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. (2000) 6:435-442.
    • (2000) Nat. Med. , vol.6 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3
  • 88
    • 0035183063 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain
    • LEWTHWAITE JC, COATES AR, TORMAY P et al.: Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain. Infect. Immun. (2001) 69:7349-7355.
    • (2001) Infect. Immun. , vol.69 , pp. 7349-7355
    • Lewthwaite, J.C.1    Coates, A.R.2    Tormay, P.3
  • 89
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: Central component of the sole mammalian LPS sensor
    • BEUTLER B: Tlr4: central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. (2000) 12:20-26.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 20-26
    • Beutler, B.1
  • 92
    • 0035873682 scopus 로고    scopus 로고
    • A Phase I study of a recombinant viruslike particle vaccine against human papillomavirus Type 11 in healthy adult volunteers
    • EVANS TG, BONNEZ W, ROSE RC et al.: A Phase I study of a recombinant viruslike particle vaccine against human papillomavirus Type 11 in healthy adult volunteers. J. Inject. Dis. (2001) 183:1485-1493.
    • (2001) J. Inject. Dis. , vol.183 , pp. 1485-1493
    • Evans, T.G.1    Bonnez, W.2    Rose, R.C.3
  • 93
    • 0036317770 scopus 로고    scopus 로고
    • Priming of human papillomavirus Type 11-specific humoral and cellular immune responses in college-aged women with a virus-like particle vaccine
    • EMENY RT, WHEELER CM, JANSEN KU et al.: Priming of human papillomavirus Type 11-specific humoral and cellular immune responses in college-aged women with a virus-like particle vaccine. J. Virol. (2002) 76:7832-7842.
    • (2002) J. Virol. , vol.76 , pp. 7832-7842
    • Emeny, R.T.1    Wheeler, C.M.2    Jansen, K.U.3
  • 94
    • 0036894973 scopus 로고    scopus 로고
    • Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer
    • KAUFMANN AM, STERN PL, RANKIN EM et al.: Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer. Clin. Cancer Res. (2002) 8:3676-3685.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3676-3685
    • Kaufmann, A.M.1    Stern, P.L.2    Rankin, E.M.3
  • 95
    • 0033559604 scopus 로고    scopus 로고
    • Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells
    • MURAKAMI M, GURSIC KJ, MARINCOLA FM, ACKLAND J, STELLER MA: Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells. Cancer Res. (1999) 59:1184-1187.
    • (1999) Cancer Res. , vol.59 , pp. 1184-1187
    • Murakami, M.1    Gursic, K.J.2    Marincola, F.M.3    Ackland, J.4    Steller, M.A.5
  • 96
    • 0033056681 scopus 로고    scopus 로고
    • Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus Type 16- and 18-positive cervical cancer
    • SANTIN AD, HERMONAT PL, RAVAGGI A et al.: Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus Type 16- and 18-positive cervical cancer. J. Virol. (1999) 73:5402-5410.
    • (1999) J. Virol. , vol.73 , pp. 5402-5410
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3
  • 97
    • 0035500930 scopus 로고    scopus 로고
    • Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6
    • EVANS M, BORYSIEWICZ LK, EVANS AS et al.: Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6. J. Immunol (2001) 167:5420-5428.
    • (2001) J. Immunol. , vol.167 , pp. 5420-5428
    • Evans, M.1    Borysiewicz, L.K.2    Evans, A.S.3
  • 98
    • 0037198442 scopus 로고    scopus 로고
    • Vaccination with HPV- 18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer
    • SANTIN AD, BELLONE S, GOKDEN M, CANNON MJ, PARHAM GP: Vaccination with HPV- 18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer. N. Engl. J. Med. (2002) 346:1752-1753.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1752-1753
    • Santin, A.D.1    Bellone, S.2    Gokden, M.3    Cannon, M.J.4    Parham, G.P.5
  • 99
    • 0035859303 scopus 로고    scopus 로고
    • Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens
    • VAN DER BURG SH, KWAPPENBERG KM, O'NEILL T et al.: Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens. Vaccine (2001) 19:3652-3660.
    • (2001) Vaccine , vol.19 , pp. 3652-3660
    • Van Der Burg, S.H.1    Kwappenberg, K.M.2    O'Neill, T.3
  • 100
    • 0036850096 scopus 로고    scopus 로고
    • Prognostic factors and new therapeutic approaches to cervical cancer
    • STANLEY MA: Prognostic factors and new therapeutic approaches to cervical cancer. Virus Res. (2002) 89:241-248.
    • (2002) Virus Res. , vol.89 , pp. 241-248
    • Stanley, M.A.1
  • 101
    • 0344771067 scopus 로고    scopus 로고
    • HPV6b virus like particles are potent immunogens without adjuvant in man
    • ZHANG LF, ZHOU J, CHEN S et al.: HPV6b virus like particles are potent immunogens without adjuvant in man. Vaccine (2000) 18:1051-1058.
    • (2000) Vaccine , vol.18 , pp. 1051-1058
    • Zhang, L.F.1    Zhou, J.2    Chen, S.3
  • 102
    • 0033813525 scopus 로고    scopus 로고
    • A Phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar inrraepithelial neoplasia who are HPV 16 positive
    • MUDERSPACH L, WILCZYNSKI S, ROMAN L et al.: A Phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar inrraepithelial neoplasia who are HPV 16 positive. Clin. Cancer Res. (2000) 6:3406-3416.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3406-3416
    • Muderspach, L.1    Wilczynski, S.2    Roman, L.3
  • 103
    • 0036091223 scopus 로고    scopus 로고
    • Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: A Phase I study of ZYC101
    • KLENCKE B, MATIJEVIC M, URBAN RG et al.: Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a Phase I study of ZYC101. Clin. Cancer Res. (2002) 8:1028-1037.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1028-1037
    • Klencke, B.1    Matijevic, M.2    Urban, R.G.3
  • 104
  • 106
    • 0034960889 scopus 로고    scopus 로고
    • Immunity to oncogenic human papillomaviruses
    • KONYA J, DILLNER J: Immunity to oncogenic human papillomaviruses. Adv. Cancer Res. (2001) 82:205-238.
    • (2001) Adv. Cancer Res. , vol.82 , pp. 205-238
    • Konya, J.1    Dillner, J.2
  • 107
    • 0035284056 scopus 로고    scopus 로고
    • Natural T-helper immunity against human papillomavirus Type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: Identification of 3 human leukocyte antigen class II-restricted epitopes
    • VAN DER BURG SH, RESSING ME, KWAPPENBERG KM et al.: Natural T-helper immunity against human papillomavirus Type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes. Int. J. Cancer. (2001) 91:612-618.
    • (2001) Int. J. Cancer. , vol.91 , pp. 612-618
    • Van Der Burg, S.H.1    Ressing, M.E.2    Kwappenberg, K.M.3


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