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Volumn 468, Issue 3, 2003, Pages 183-189

The α2A-adrenoceptor subtype is not involved in inflammatory hyperalgesia or morphine-induced antinociception

Author keywords

Carrageenan; Hyperalgesia; Morphine; Pain; 2 Adrenoceptor subtype

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CARRAGEENAN; MORPHINE; NALOXONE; RECEPTOR SUBTYPE;

EID: 0037499834     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01677-7     Document Type: Article
Times cited : (25)

References (42)
  • 2
    • 0025100514 scopus 로고
    • Receptor changes in the spinal cord of sheep associated with exposure to chronic pain
    • Brandt S., Livingston A. Receptor changes in the spinal cord of sheep associated with exposure to chronic pain. Pain. 42:1990;323-329.
    • (1990) Pain , vol.42 , pp. 323-329
    • Brandt, S.1    Livingston, A.2
  • 3
    • 0019946031 scopus 로고
    • Interactions of drugs active at opiate receptors and drugs active at alpha-2-receptors on various test systems
    • Browning S., Lawrence D., Livingstone A., Morris B. Interactions of drugs active at opiate receptors and drugs active at alpha-2-receptors on various test systems. Br. J. Pharmacol. 77:1982;487-491.
    • (1982) Br. J. Pharmacol. , vol.77 , pp. 487-491
    • Browning, S.1    Lawrence, D.2    Livingstone, A.3    Morris, B.4
  • 6
    • 0023132362 scopus 로고
    • Complex temporal changes in 5-hydroxytryptamine synthesis in the central nervous system induced by experimental polyarthritis in the rat
    • Godefroy F., Weil-Fugazza J., Besson J.M. Complex temporal changes in 5-hydroxytryptamine synthesis in the central nervous system induced by experimental polyarthritis in the rat. Pain. 28:1987;223-238.
    • (1987) Pain , vol.28 , pp. 223-238
    • Godefroy, F.1    Weil-Fugazza, J.2    Besson, J.M.3
  • 7
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 32:1988;77-88.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 8
    • 0035229145 scopus 로고    scopus 로고
    • Transgenic mouse models of α2-adrenergic receptor subtype function
    • Hein L. Transgenic mouse models of α2-adrenergic receptor subtype function. Rev. Physiol. Biochem. Pharmacol. 142:2001;161-185.
    • (2001) Rev. Physiol. Biochem. Pharmacol. , vol.142 , pp. 161-185
    • Hein, L.1
  • 9
    • 0033547241 scopus 로고    scopus 로고
    • Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
    • Hein L., Altman J.D., Kobilka B.K. Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission. Nature. 402:1999;181-184.
    • (1999) Nature , vol.402 , pp. 181-184
    • Hein, L.1    Altman, J.D.2    Kobilka, B.K.3
  • 10
    • 0033523385 scopus 로고    scopus 로고
    • 2-adrenergic antagonist idazoxan in inflammation
    • 2-adrenergic antagonist idazoxan in inflammation. Brain Res. 840:1999;106-114.
    • (1999) Brain Res. , vol.840 , pp. 106-114
    • Herrero, J.F.1    Solano, R.E.2
  • 11
    • 0030609171 scopus 로고    scopus 로고
    • Assessment of the role of alpha-2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice
    • Hunter J.C., Fontana D.J., Hedley L.R., Jasper J.R., Lewis R., Link R.E., Secchi R., Sutton J., Eglen R.M. Assessment of the role of alpha-2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice. Br. J. Pharmacol. 122:1997;1339-1344.
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1339-1344
    • Hunter, J.C.1    Fontana, D.J.2    Hedley, L.R.3    Jasper, J.R.4    Lewis, R.5    Link, R.E.6    Secchi, R.7    Sutton, J.8    Eglen, R.M.9
  • 12
    • 0026084861 scopus 로고
    • Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: A possible involvement of noradrenergic mechanisms
    • Hylden J.L., Thomas D.A., Iadarola M.J., Nahin R.L., Dubner R. Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: a possible involvement of noradrenergic mechanisms. Eur. J. Pharmacol. 194:1991;135-143.
    • (1991) Eur. J. Pharmacol. , vol.194 , pp. 135-143
    • Hylden, J.L.1    Thomas, D.A.2    Iadarola, M.J.3    Nahin, R.L.4    Dubner, R.5
  • 13
    • 0027941976 scopus 로고
    • Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50488H against noxious thermal, mechanical and inflammatory stimuli
    • Idänpään-Heikkilä J.J., Kalso E.A., Seppälä T. Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50488H against noxious thermal, mechanical and inflammatory stimuli. J. Pharmacol. Exp. Ther. 271:1994;1306-1313.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1306-1313
    • Idänpään-Heikkilä, J.J.1    Kalso, E.A.2    Seppälä, T.3
  • 14
    • 0034087475 scopus 로고    scopus 로고
    • In vivo gene modification elucidates subtype specific functions of alpha-2-adrenergic receptors
    • Kable J.W., Murrin L.C., Bylund D.B. In vivo gene modification elucidates subtype specific functions of alpha-2-adrenergic receptors. J. Pharmacol. Exp. Ther. 293:2000;1-7.
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 1-7
    • Kable, J.W.1    Murrin, L.C.2    Bylund, D.B.3
  • 15
    • 0020621399 scopus 로고
    • The analgesic effect of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in the arthritic rat
    • Kayser V., Guilbaud G. The analgesic effect of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in the arthritic rat. Brain Res. 267:1983;131-138.
    • (1983) Brain Res. , vol.267 , pp. 131-138
    • Kayser, V.1    Guilbaud, G.2
  • 16
    • 0034175743 scopus 로고    scopus 로고
    • 2A-adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice
    • 2A-adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice. Pain. 85:2000;345-358.
    • (2000) Pain , vol.85 , pp. 345-358
    • Kingery, W.S.1    Guo, T.Z.2    Davies, F.M.3    Limbird, L.4    Maze, M.5
  • 19
    • 0030610424 scopus 로고    scopus 로고
    • Substitution of a mutant alpha-2A-adrenergic receptor via 'hit and run' gene targeting reveals the role of this subtype in sedative, analgesic and anesthetic-sparing responses in vivo
    • Lakhlani P.P., MacMillan L.B., Guo T.Z., McCool B.A., Lovinger D.M., Maze M., Limbird L.E. Substitution of a mutant alpha-2A-adrenergic receptor via 'hit and run' gene targeting reveals the role of this subtype in sedative, analgesic and anesthetic-sparing responses in vivo. Proc. Natl. Acad. Sci. U. S. A. 94:1997;9950-9955.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 9950-9955
    • Lakhlani, P.P.1    MacMillan, L.B.2    Guo, T.Z.3    McCool, B.A.4    Lovinger, D.M.5    Maze, M.6    Limbird, L.E.7
  • 20
    • 0035042044 scopus 로고    scopus 로고
    • Transgenic studies of pain and analgesia: Mutation or background genotype?
    • Lariviere W.R., Chesler E.J., Mogil J.S. Transgenic studies of pain and analgesia: mutation or background genotype? J. Pharmacol. Exp. Ther. 297:2001;467-473.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 467-473
    • Lariviere, W.R.1    Chesler, E.J.2    Mogil, J.S.3
  • 21
    • 0034747195 scopus 로고    scopus 로고
    • 2A-Adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes
    • 2A-Adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes. J. Pharmacol. Exp. Ther. 299:2001;939-944.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 939-944
    • Li, X.1    Eisenach, J.C.2
  • 22
    • 0030844448 scopus 로고    scopus 로고
    • Gene targeting - Homing in on alpha-2-adrenoceptor subtype function
    • MacDonald E., Kobilka B.K., Scheinin M. Gene targeting - homing in on alpha-2-adrenoceptor subtype function. Trends Pharmacol. Sci. 18:1997;211-219.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 211-219
    • MacDonald, E.1    Kobilka, B.K.2    Scheinin, M.3
  • 24
    • 0028983153 scopus 로고
    • Influence of selective alpha-2-adrenergic agents on mustard oil-induced central hyperalgesia in rats
    • Mansikka H., Pertovaara A. Influence of selective alpha-2-adrenergic agents on mustard oil-induced central hyperalgesia in rats. Eur. J. Pharmacol. 281:1995;43-48.
    • (1995) Eur. J. Pharmacol. , vol.281 , pp. 43-48
    • Mansikka, H.1    Pertovaara, A.2
  • 26
    • 0027435354 scopus 로고
    • Expression of multiple alpha adrenergic receptor subtypes messenger RNAs in the adult rat brain
    • McCune S.K., Voigt M.M., Hill J.M. Expression of multiple alpha adrenergic receptor subtypes messenger RNAs in the adult rat brain. Neuroscience. 57:1993;143-151.
    • (1993) Neuroscience , vol.57 , pp. 143-151
    • McCune, S.K.1    Voigt, M.M.2    Hill, J.M.3
  • 28
    • 0030201051 scopus 로고    scopus 로고
    • The distribution and significance of CNS adrenoceptors examined with in situ hybridization
    • Nicholas A.P., Hökfelt T., Pieribone V.A. The distribution and significance of CNS adrenoceptors examined with in situ hybridization. Trends Pharmacol. Sci. 17:1996;245-255.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 245-255
    • Nicholas, A.P.1    Hökfelt, T.2    Pieribone, V.A.3
  • 29
    • 0024536612 scopus 로고
    • Antinociceptive interactions between alpha-2-adrenergic and opiate agonists at the spinal level in rodents
    • Ossipov M.H., Suarez L.J., Spaulding T.C. Antinociceptive interactions between alpha-2-adrenergic and opiate agonists at the spinal level in rodents. Anesth. Analg. 68:1989;194-200.
    • (1989) Anesth. Analg. , vol.68 , pp. 194-200
    • Ossipov, M.H.1    Suarez, L.J.2    Spaulding, T.C.3
  • 30
    • 0033959051 scopus 로고    scopus 로고
    • Enhanced δ-opioid receptor-mediated antinociception in μ-opioid receptor-deficient mice
    • Qiu C., Sora I., Ren K., Uhl G., Dubner R. Enhanced δ-opioid receptor-mediated antinociception in μ-opioid receptor-deficient mice. Eur. J. Pharmacol. 387:2000;163-169.
    • (2000) Eur. J. Pharmacol. , vol.387 , pp. 163-169
    • Qiu, C.1    Sora, I.2    Ren, K.3    Uhl, G.4    Dubner, R.5
  • 32
    • 0035815077 scopus 로고    scopus 로고
    • Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target. Studies in transgenic mouse models
    • Scheinin M., Sallinen J., Haapalinna A. Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target. Studies in transgenic mouse models. Life Sci. 68:2001;2277-2285.
    • (2001) Life Sci. , vol.68 , pp. 2277-2285
    • Scheinin, M.1    Sallinen, J.2    Haapalinna, A.3
  • 34
    • 0028354005 scopus 로고
    • 2-adrenergic controls and spinal morphine potency in inflammation
    • 2-adrenergic controls and spinal morphine potency in inflammation. NeuroReport. 5:1994;469-472.
    • (1994) NeuroReport , vol.5 , pp. 469-472
    • Stanfa, L.C.1    Dickenson, A.H.2
  • 35
    • 0026761106 scopus 로고
    • Alterations in neuronal excitability and the potency of spinal μ, δ, and κ opioids after carrageenan-induced inflammation
    • Stanfa L.C., Sullivan A.F., Dickenson A.H. Alterations in neuronal excitability and the potency of spinal μ, δ, and κ opioids after carrageenan-induced inflammation. Pain. 50:1992;345-354.
    • (1992) Pain , vol.50 , pp. 345-354
    • Stanfa, L.C.1    Sullivan, A.F.2    Dickenson, A.H.3
  • 36
    • 0030611098 scopus 로고    scopus 로고
    • The alpha-2A-adrenergic receptor subtype mediates spinal analgesia evoked by alpha-2-agonists and is necessary for spinal adrenergic-opioid synergy
    • Stone L.S., MacMillan L.B., Kitto K.F., Limbird L.E., Wilcox G.L. The alpha-2A-adrenergic receptor subtype mediates spinal analgesia evoked by alpha-2-agonists and is necessary for spinal adrenergic-opioid synergy. J. Neurosci. 17:1997;7157-7165.
    • (1997) J. Neurosci. , vol.17 , pp. 7157-7165
    • Stone, L.S.1    MacMillan, L.B.2    Kitto, K.F.3    Limbird, L.E.4    Wilcox, G.L.5
  • 37
    • 0032129192 scopus 로고    scopus 로고
    • Differential distribution of alpha-2A and alpha-2C-adrenergic receptor immunoreactivity in the rat spinal cord
    • Stone L.S., Broberger C., Vulchanova L., Wilcox G.L., Hökfelt T., Riedl M.S., Elde R. Differential distribution of alpha-2A and alpha-2C-adrenergic receptor immunoreactivity in the rat spinal cord. J. Neurosci. 18:1998;5928-5937.
    • (1998) J. Neurosci. , vol.18 , pp. 5928-5937
    • Stone, L.S.1    Broberger, C.2    Vulchanova, L.3    Wilcox, G.L.4    Hökfelt, T.5    Riedl, M.S.6    Elde, R.7
  • 38
    • 0023277297 scopus 로고
    • 2-Adrenoceptor modulation of nociception in rat spinal cord: Location, effects and interactions with morphine
    • 2-Adrenoceptor modulation of nociception in rat spinal cord: location, effects and interactions with morphine. Eur. J. Pharmacol. 138:1987;169-177.
    • (1987) Eur. J. Pharmacol. , vol.138 , pp. 169-177
    • Sullivan, A.F.1    Dashwood, M.R.2    Dickenson, A.H.3
  • 40
    • 0029761930 scopus 로고    scopus 로고
    • Expression of alpha-2-adrenergic receptor subtypes in the mouse brain: Evaluation of spatial and temporal information imparted by 3 kb of 5′ regulatory sequence for the alpha-2A-AR receptor gene in transgenic animals
    • Wang R., MacMillan L.B., Fremeau R.T. Jr., Magnuson M.A., Lindner J., Limbird L.E. Expression of alpha-2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5′ regulatory sequence for the alpha-2A-AR receptor gene in transgenic animals. Neuroscience. 74:1996;199-218.
    • (1996) Neuroscience , vol.74 , pp. 199-218
    • Wang, R.1    MacMillan, L.B.2    Fremeau R.T., Jr.3    Magnuson, M.A.4    Lindner, J.5    Limbird, L.E.6
  • 41
    • 0022504916 scopus 로고
    • Increased norepinephrine and uric acid levels in the spinal cord of arthritic rats
    • Weil-Fugazza J., Godefroy F., Manceau V., Besson J.M. Increased norepinephrine and uric acid levels in the spinal cord of arthritic rats. Brain Res. 374:1986;190-194.
    • (1986) Brain Res. , vol.374 , pp. 190-194
    • Weil-Fugazza, J.1    Godefroy, F.2    Manceau, V.3    Besson, J.M.4
  • 42
    • 0023096148 scopus 로고
    • Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord
    • Wilcox G.L., Carlsson K.H., Jochim A., Jurna I. Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord. Brain Res. 405:1987;84-93.
    • (1987) Brain Res. , vol.405 , pp. 84-93
    • Wilcox, G.L.1    Carlsson, K.H.2    Jochim, A.3    Jurna, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.