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Volumn 161, Issue 8, 1998, Pages 4437-4446

Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL MEDIATED CYTOTOXICITY; DEMYELINATION; FEMALE; GENE EXPRESSION; IMMUNOPATHOLOGY; INFLAMMATORY INFILTRATE; MOUSE; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RELAPSE; REMISSION;

EID: 0032532022     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (183)

References (56)
  • 1
    • 0001045439 scopus 로고
    • Immunologic aspects of Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease
    • Miller, S. D., and S. J. Gerety. 1990. Immunologic aspects of Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. Semin. Virol. 1:263.
    • (1990) Semin. Virol. , vol.1 , pp. 263
    • Miller, S.D.1    Gerety, S.J.2
  • 2
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell mediated demyelinating diseases
    • Miller, S. D., and W. J. Karpus. 1994. The immunopathogenesis and regulation of T-cell mediated demyelinating diseases. Immunol. Today 15:356.
    • (1994) Immunol. Today , vol.15 , pp. 356
    • Miller, S.D.1    Karpus, W.J.2
  • 3
    • 0018713491 scopus 로고
    • Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus
    • Lipton, H. L., and M. C. Dal Canto. 1979. Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus. Infect. Immun. 26:369.
    • (1979) Infect. Immun. , vol.26 , pp. 369
    • Lipton, H.L.1    Dal Canto, M.C.2
  • 4
    • 0019359228 scopus 로고
    • Relapsing experimental allergic encephalomyelitis in the SJL/J mouse
    • Brown, A. M., and D. E. McFarlin. 1981. Relapsing experimental allergic encephalomyelitis in the SJL/J mouse. Lab. Invest. 45:278.
    • (1981) Lab. Invest. , vol.45 , pp. 278
    • Brown, A.M.1    McFarlin, D.E.2
  • 5
    • 0018889180 scopus 로고
    • Persistent Theiler's murine encephalomyelitis virus infection in mice depends on plaque size
    • Lipton, H. L. 1980. Persistent Theiler's murine encephalomyelitis virus infection in mice depends on plaque size. J. Gen. Virol. 46:169.
    • (1980) J. Gen. Virol. , vol.46 , pp. 169
    • Lipton, H.L.1
  • 6
    • 0025174370 scopus 로고
    • Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides
    • Kennedy, M. K., L. J. Tan, M. C. Dal Canto, V. K. Tuohy, Z. J. Lu, J. L. Trotter, and S. D. Miller. 1990. Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides. J. Immunol. 144:909.
    • (1990) J. Immunol. , vol.144 , pp. 909
    • Kennedy, M.K.1    Tan, L.J.2    Dal Canto, M.C.3    Tuohy, V.K.4    Lu, Z.J.5    Trotter, J.L.6    Miller, S.D.7
  • 7
    • 0026721247 scopus 로고
    • Induction of active and adoptive chronic-relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein
    • McRae, B. L., M. K. Kennedy, L. J. Tan, M. C. Dal Canto, and S. D. Miller. 1992. Induction of active and adoptive chronic-relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein. J. Neuroimmunol. 38:229.
    • (1992) J. Neuroimmunol. , vol.38 , pp. 229
    • McRae, B.L.1    Kennedy, M.K.2    Tan, L.J.3    Dal Canto, M.C.4    Miller, S.D.5
  • 8
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the relapsing pathology of EAE in the SJL/J mouse
    • McRae, B. L., C. L. Vanderlugt, M. C. Dal Canto, and S. D. Miller. 1995. Functional evidence for epitope spreading in the relapsing pathology of EAE in the SJL/J mouse. J. Exp. Med. 182:75.
    • (1995) J. Exp. Med. , vol.182 , pp. 75
    • McRae, B.L.1    Vanderlugt, C.L.2    Dal Canto, M.C.3    Miller, S.D.4
  • 11
    • 0023794099 scopus 로고
    • Increased production of interferon γ and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?
    • Beck, J., P. Rondot, L. Catinot, E. Falcoff, H. Kirchner, and J. Wietzerbin. 1988. Increased production of interferon γ and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? Acta Neurol. Scand. 78:318.
    • (1988) Acta Neurol. Scand. , vol.78 , pp. 318
    • Beck, J.1    Rondot, P.2    Catinot, L.3    Falcoff, E.4    Kirchner, H.5    Wietzerbin, J.6
  • 12
    • 0025155943 scopus 로고
    • Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination
    • Miller, S. D., S. J. Gerety, M. K. Kennedy, J. D. Peterson, J. L. Trotter, V. K. Tuohy, C. Waltenbaugh, M. C. Dal Canto, and H. L. Lipton. 1990. Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination. J. Neuroimmunol. 26:9.
    • (1990) J. Neuroimmunol. , vol.26 , pp. 9
    • Miller, S.D.1    Gerety, S.J.2    Kennedy, M.K.3    Peterson, J.D.4    Trotter, J.L.5    Tuohy, V.K.6    Waltenbaugh, C.7    Dal Canto, M.C.8    Lipton, H.L.9
  • 13
    • 0023194093 scopus 로고
    • Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Cross-specificity among TMEV substrains and related picornaviruses, but not myelin proteins
    • Miller, S. D., R. J. Clatch, D. C. Pevear, J. L. Trotter, and H. L. Lipton. 1987. Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Cross-specificity among TMEV substrains and related picornaviruses, but not myelin proteins. J. Immunol. 138:3776.
    • (1987) J. Immunol. , vol.138 , pp. 3776
    • Miller, S.D.1    Clatch, R.J.2    Pevear, D.C.3    Trotter, J.L.4    Lipton, H.L.5
  • 14
    • 0023251015 scopus 로고
    • The effect of L3T4 T cell depletion on the pathogenesis of Theiler's murine encephalomyelitis virus infection in CBA mice
    • Welsh, C. J., P. Tonks, A. A. Nash, and W. F. Blakemore. 1987. The effect of L3T4 T cell depletion on the pathogenesis of Theiler's murine encephalomyelitis virus infection in CBA mice. J. Gen. Virol. 68:1659.
    • (1987) J. Gen. Virol. , vol.68 , pp. 1659
    • Welsh, C.J.1    Tonks, P.2    Nash, A.A.3    Blakemore, W.F.4
  • 16
    • 0029056669 scopus 로고
    • Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction
    • Karpus, W. J., J. G. Pope, J. D. Peterson, M. C. Dal Canto, and S. D. Miller. 1995. Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction. J. Immunol. 155:947.
    • (1995) J. Immunol. , vol.155 , pp. 947
    • Karpus, W.J.1    Pope, J.G.2    Peterson, J.D.3    Dal Canto, M.C.4    Miller, S.D.5
  • 18
    • 0023856205 scopus 로고
    • Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis
    • McDonald, A. H., and R. H. Swanborg. 1988. Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis. J. Immunol. 140:1132.
    • (1988) J. Immunol. , vol.140 , pp. 1132
    • McDonald, A.H.1    Swanborg, R.H.2
  • 19
    • 0021913219 scopus 로고
    • Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker
    • Waldor, M. K., S. Sriram, R. Hardy, L. A. Herzenberg, L. Lanier, M. Lim, and L. Steinman. 1985. Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker. Science 227:415.
    • (1985) Science , vol.227 , pp. 415
    • Waldor, M.K.1    Sriram, S.2    Hardy, R.3    Herzenberg, L.A.4    Lanier, L.5    Lim, M.6    Steinman, L.7
  • 20
    • 0025892475 scopus 로고
    • Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1
    • Racke, M. K., S. Dhib-Jalbut, B. Cannella, P. S. Albert, C. S. Raine, and D. E. McFarlin. 1991. Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1. J. Immunol. 146: 3012.
    • (1991) J. Immunol. , vol.146 , pp. 3012
    • Racke, M.K.1    Dhib-Jalbut, S.2    Cannella, B.3    Albert, P.S.4    Raine, C.S.5    McFarlin, D.E.6
  • 21
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy, M. K., D. S. Torrance, K. S. Picha, and K. M. Mohler. 1992. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149:2496.
    • (1992) J. Immunol. , vol.149 , pp. 2496
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 24
    • 0025804860 scopus 로고
    • Class H-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. IV. Identification of an immunodominant T cell determinant on the N-terminal end of the VP2 capsid protein in susceptible SJL/J mice
    • Gerety, S. J., R. J. Clatch, H. L. Lipton, R. G. Goswami, M. K. Rundell, and S. D. Miller. 1991. Class H-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. IV. Identification of an immunodominant T cell determinant on the N-terminal end of the VP2 capsid protein in susceptible SJL/J mice. J. Immunol. 146:2401.
    • (1991) J. Immunol. , vol.146 , pp. 2401
    • Gerety, S.J.1    Clatch, R.J.2    Lipton, H.L.3    Goswami, R.G.4    Rundell, M.K.5    Miller, S.D.6
  • 25
    • 0029742433 scopus 로고    scopus 로고
    • IL-10 fails to abrogate experimental autoimmune encephalomyelitis
    • Cannella, B., Y. L. Gao, C. Brosnan, and C. S. Raine. 1996. IL-10 fails to abrogate experimental autoimmune encephalomyelitis. J. Neurosci. Res. 45:735.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 735
    • Cannella, B.1    Gao, Y.L.2    Brosnan, C.3    Raine, C.S.4
  • 26
    • 0030738659 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells
    • Mathisen, P. M., M. Yu, J. M. Johnson, J. A. Drazba, and V. K. Touhy. 1997. Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells. J. Exp. Med. 186:159.
    • (1997) J. Exp. Med. , vol.186 , pp. 159
    • Mathisen, P.M.1    Yu, M.2    Johnson, J.M.3    Drazba, J.A.4    Touhy, V.K.5
  • 27
    • 0030775998 scopus 로고    scopus 로고
    • Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE
    • Vanderlugt, C. L., N. J. Karandikar, D. J. Lenschow, M. C. Dal Canto, J. A. Bluestone, and S. D. Miller. 1997. Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE. J. Neuroimmunol. 79:113.
    • (1997) J. Neuroimmunol. , vol.79 , pp. 113
    • Vanderlugt, C.L.1    Karandikar, N.J.2    Lenschow, D.J.3    Dal Canto, M.C.4    Bluestone, J.A.5    Miller, S.D.6
  • 28
    • 0028212497 scopus 로고
    • Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice
    • Gerety, S. J., W. J. Karpus, A. R. Cubbon, R. G. Goswami, M. K. Rundell, J. D. Peterson, and S. D. Miller. 1994. Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice. J. Immunol. 152:908.
    • (1994) J. Immunol. , vol.152 , pp. 908
    • Gerety, S.J.1    Karpus, W.J.2    Cubbon, A.R.3    Goswami, R.G.4    Rundell, M.K.5    Peterson, J.D.6    Miller, S.D.7
  • 29
    • 0028020309 scopus 로고
    • A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244)
    • Yauch, R. L., and B. S. Kim. 1994. A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244). J. Immunol. 153:4508.
    • (1994) J. Immunol. , vol.153 , pp. 4508
    • Yauch, R.L.1    Kim, B.S.2
  • 30
    • 0028872064 scopus 로고
    • Two models of multiple sclerosis: Experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection - A pathological and immunological comparison
    • Dal Canto, M. C., R. W. Melvold, B. S. Kim, and S. D. Miller. 1995. Two models of multiple sclerosis: experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection - a pathological and immunological comparison. Microsc. Res. Tech. 32:215.
    • (1995) Microsc. Res. Tech. , vol.32 , pp. 215
    • Dal Canto, M.C.1    Melvold, R.W.2    Kim, B.S.3    Miller, S.D.4
  • 31
    • 0026771135 scopus 로고
    • Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β)
    • Ruddle, N. H. 1992. Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β). Curr. Opin. Immunol. 4:327.
    • (1992) Curr. Opin. Immunol. , vol.4 , pp. 327
    • Ruddle, N.H.1
  • 32
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • Karpus, W. J., N. W. Lukacs, B. L. McRae, R. M. Streiter, S. L. Kunkel, and S. D. Miller. 1995. An important role for the chemokine macrophage inflammatory protein-1 α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155:5003.
    • (1995) J. Immunol. , vol.155 , pp. 5003
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Streiter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 33
    • 0030613627 scopus 로고    scopus 로고
    • MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation
    • Karpus, W. J., and K. J. Kennedy. 1997. MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation. J. Leukocyte Biol. 62:681.
    • (1997) J. Leukocyte Biol. , vol.62 , pp. 681
    • Karpus, W.J.1    Kennedy, K.J.2
  • 34
    • 0025607948 scopus 로고
    • Direct injection of cytokines into the spinal cord causes autoimmune encephalomyelitis-like inflammation
    • Simmons, R. D., and D. O. Willenborg. 1990. Direct injection of cytokines into the spinal cord causes autoimmune encephalomyelitis-like inflammation. J. Neurol. Sci. 100:37.
    • (1990) J. Neurol. Sci. , vol.100 , pp. 37
    • Simmons, R.D.1    Willenborg, D.O.2
  • 36
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis
    • Ruddle, N. H., C. M. Bergman, K. M. McGrath, E. G. Lingenheld, M. L. Grunnet, S. J. Padula, and R. B. Clark. 1990. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J. Exp. Med. 172:1193.
    • (1990) J. Exp. Med. , vol.172 , pp. 1193
    • Ruddle, N.H.1    Bergman, C.M.2    McGrath, K.M.3    Lingenheld, E.G.4    Grunnet, M.L.5    Padula, S.J.6    Clark, R.B.7
  • 37
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-α production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • Powell, M. B., D. Mitchell, J. Lederman, J. Buckmeier, S. S. Zamvil, M. Graham, N. H. Ruddle, and L. Steinman. 1990. Lymphotoxin and tumor necrosis factor-α production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int. Immunol. 2:539.
    • (1990) Int. Immunol. , vol.2 , pp. 539
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6    Ruddle, N.H.7    Steinman, L.8
  • 38
    • 0030856118 scopus 로고    scopus 로고
    • A critical role for lymphotoxin in experimental allergic encephalomyelitis
    • Suen, W. E., C. M. Bergman, P. Hjelmström, and N. H. Ruddle. 1997. A critical role for lymphotoxin in experimental allergic encephalomyelitis. J. Exp. Med. 186:1233.
    • (1997) J. Exp. Med. , vol.186 , pp. 1233
    • Suen, W.E.1    Bergman, C.M.2    Hjelmström, P.3    Ruddle, N.H.4
  • 39
    • 0027339073 scopus 로고
    • Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus
    • Peterson, J. D., W. J. Karpus, R. J. Clatch, and S. D. Miller. 1993. Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus. Eur. J. Immunol. 23:46.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 46
    • Peterson, J.D.1    Karpus, W.J.2    Clatch, R.J.3    Miller, S.D.4
  • 40
    • 0028983573 scopus 로고
    • TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis: Regulation by Th1 cytokines
    • Renno, T., M. Krakowski, C. Piccirillo, J. Y. Lin, and T. Owens. 1995. TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis: regulation by Th1 cytokines. J. Immunol. 154:944.
    • (1995) J. Immunol. , vol.154 , pp. 944
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.Y.4    Owens, T.5
  • 41
    • 0027509709 scopus 로고
    • Theiler's murine encephalomyelitis virus induces tumour necrosis factor-α in murine astrocyte cell cultures
    • Sierra, A., and N. Rubio. 1993. Theiler's murine encephalomyelitis virus induces tumour necrosis factor-α in murine astrocyte cell cultures. Immunology 78:399.
    • (1993) Immunology , vol.78 , pp. 399
    • Sierra, A.1    Rubio, N.2
  • 43
    • 0030587910 scopus 로고    scopus 로고
    • IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Willenborg, D. O., S. Fordham, C. C. Bernard, W. B. Cowden, and I. A. Ramshaw. 1996. IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157:3223.
    • (1996) J. Immunol. , vol.157 , pp. 3223
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 44
    • 0030918326 scopus 로고    scopus 로고
    • Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis
    • Frei, K., H. P. Eugster, M. Bopst, C. S. Constantinescu, E. Lavi, and A. Fontana. 1998. Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis. J. Exp. Med. 185:2177.
    • (1998) J. Exp. Med. , vol.185 , pp. 2177
    • Frei, K.1    Eugster, H.P.2    Bopst, M.3    Constantinescu, C.S.4    Lavi, E.5    Fontana, A.6
  • 46
    • 0031043631 scopus 로고    scopus 로고
    • Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis
    • Tanuma, N., T. Kojima, T. Shin, Y. Aikawa, T. Kohji, Y. Ishihara, and Y. Matsumoto. 1997. Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis. J. Neuroimmunol. 73:197.
    • (1997) J. Neuroimmunol. , vol.73 , pp. 197
    • Tanuma, N.1    Kojima, T.2    Shin, T.3    Aikawa, Y.4    Kohji, T.5    Ishihara, Y.6    Matsumoto, Y.7
  • 47
    • 0028346888 scopus 로고
    • Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice
    • Wogensen, L., M. S. Lee, and N. Sarvetnick. 1994. Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice. J. Exp. Med. 179:1379.
    • (1994) J. Exp. Med. , vol.179 , pp. 1379
    • Wogensen, L.1    Lee, M.S.2    Sarvetnick, N.3
  • 48
    • 0026696776 scopus 로고
    • + suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion
    • + suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Immunol. 22:1757.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1757
    • Karpus, W.J.1    Gould, K.E.2    Swanborg, R.H.3
  • 49
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen, Y., V. K. Kuchroo, J. Inobe, D. A. Hafler, and H. L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265:1237.
    • (1994) Science , vol.265 , pp. 1237
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 51
    • 0030879734 scopus 로고    scopus 로고
    • Mechanism underlying counterregulation of autoimmune diabetes by IL-4
    • Mueller, R. 1997. Mechanism underlying counterregulation of autoimmune diabetes by IL-4. Immunity 7:411.
    • (1997) Immunity , vol.7 , pp. 411
    • Mueller, R.1
  • 52
    • 0030911059 scopus 로고    scopus 로고
    • Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection
    • Sato, S., S. L. Reiner, M. A. Jensen, and R. P. Roos. 1997. Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection. J. Neuroimmunol. 76:213.
    • (1997) J. Neuroimmunol. , vol.76 , pp. 213
    • Sato, S.1    Reiner, S.L.2    Jensen, M.A.3    Roos, R.P.4
  • 53
    • 0025304856 scopus 로고
    • Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV)
    • Clatch, R. J., S. D. Miller, R. Metzner, M. C. Dal Canto, and H. L. Lipton. 1990. Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV). Virology 176:244.
    • (1990) Virology , vol.176 , pp. 244
    • Clatch, R.J.1    Miller, S.D.2    Metzner, R.3    Dal Canto, M.C.4    Lipton, H.L.5
  • 54
    • 0028902180 scopus 로고
    • The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Lipton, H. L., G. Twaddle, and M. L. Jelachich. 1995. The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease. J. Virol. 69:2525.
    • (1995) J. Virol. , vol.69 , pp. 2525
    • Lipton, H.L.1    Twaddle, G.2    Jelachich, M.L.3
  • 56
    • 0031667213 scopus 로고    scopus 로고
    • Characterization of and functional antigen presentation by central nervous system mononuclear cells from mice infected with Theiler's murine encephalomyelitis virus
    • In press
    • Pope, J. G., C. L. Vanderlugt, H. L. Lipton, S. M. Rahbe, and S. D. Miller. 1998. Characterization of and functional antigen presentation by central nervous system mononuclear cells from mice infected with Theiler's murine encephalomyelitis virus. J. Virol. In press.
    • (1998) J. Virol.
    • Pope, J.G.1    Vanderlugt, C.L.2    Lipton, H.L.3    Rahbe, S.M.4    Miller, S.D.5


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