-
1
-
-
0029820178
-
Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients
-
Agarwal V, Bulun SE, Leitch M, Rohrich R, Simpson ER (1996) Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients. J Clin Endocrinol Metab 81: 3843-3849
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3843-3849
-
-
Agarwal, V.1
Bulun, S.E.2
Leitch, M.3
Rohrich, R.4
Simpson, E.R.5
-
2
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with breast cancer: First results of the ATAC randomised trial
-
ATAC Trialist Group (2002) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with breast cancer: first results of the ATAC randomised trial. Lancet 359: 2131-2139
-
(2002)
Lancet
, vol.359
, pp. 2131-2139
-
-
-
3
-
-
0032922590
-
Blocking signalling through the gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumour cells to etoposide and cisplatin-mediated cytotoxicity
-
Borsellino N, Bonavida B, Ciliberto G, Toniatti C, Travali S, D'Alessandro N (1999) Blocking signalling through the gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumour cells to etoposide and cisplatin-mediated cytotoxicity. Cancer 85: 134-144
-
(1999)
Cancer
, vol.85
, pp. 134-144
-
-
Borsellino, N.1
Bonavida, B.2
Ciliberto, G.3
Toniatti, C.4
Travali, S.5
D'Alessandro, N.6
-
4
-
-
0031054095
-
A phase III trial comparing anastrozole (1 and 10 milligrams), a potent and selective aromatase inhibitor, with megestrol acetate in postmenopausal women with advanced breast carcinoma
-
Buzdar AU, Jones SE, Vogel CL, Wotter J, Plourde P, Webster A (1997) A phase III trial comparing anastrozole (1 and 10 milligrams), a potent and selective aromatase inhibitor, with megestrol acetate in postmenopausal women with advanced breast carcinoma. Cancer 79: 730-739
-
(1997)
Cancer
, vol.79
, pp. 730-739
-
-
Buzdar, A.U.1
Jones, S.E.2
Vogel, C.L.3
Wotter, J.4
Plourde, P.5
Webster, A.6
-
5
-
-
0343238244
-
Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCap prostate cancer cells
-
Chen T, Wang LH, Farrar WL (2000) Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCap prostate cancer cells. Cancer Res 60: 2132-2135
-
(2000)
Cancer Res
, vol.60
, pp. 2132-2135
-
-
Chen, T.1
Wang, L.H.2
Farrar, W.L.3
-
6
-
-
0029812490
-
Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death
-
Demartis A, Bernassola F, Savino R, Melino G, Ciliberto G (1996) Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death. Cancer Res 56: 4213-4218
-
(1996)
Cancer Res
, vol.56
, pp. 4213-4218
-
-
Demartis, A.1
Bernassola, F.2
Savino, R.3
Melino, G.4
Ciliberto, G.5
-
7
-
-
0034885923
-
Effect of letrozole on the lipid profile in postmenopausal women with breast cancer
-
Elisaf MS, Bairaktari ETh, Nicolaides C, Kakaidi B, Tzallas CS, Katsaraki A, Pavlides NA (2001) Effect of letrozole on the lipid profile in postmenopausal women with breast cancer. Eur J Cancer 37: 1510-1513
-
(2001)
Eur J Cancer
, vol.37
, pp. 1510-1513
-
-
Elisaf, M.S.1
Bairaktari, E.T.H.2
Nicolaides, C.3
Kakaidi, B.4
Tzallas, C.S.5
Katsaraki, A.6
Pavlides, N.A.7
-
9
-
-
0027362649
-
Tissue-specific expression of the human aromatase cytochrome P450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis
-
Harada N, Utsumi T, Takagi Y (1993) Tissue-specific expression of the human aromatase cytochrome P450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proc Natl Acad Sci USA 90: 11312-11316
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11312-11316
-
-
Harada, N.1
Utsumi, T.2
Takagi, Y.3
-
10
-
-
0015984830
-
Plasma precursors of estrogen 11. Correlation of the extent of conversion of plasma androstenedione to estrone with age
-
Hemsell DL, Grodin JM, Brenner PF, Siiteri PK, MacDonald PC (1974) Plasma precursors of estrogen 11. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab 38: 476-479
-
(1974)
J Clin Endocrinol Metab
, vol.38
, pp. 476-479
-
-
Hemsell, D.L.1
Grodin, J.M.2
Brenner, P.F.3
Siiteri, P.K.4
MacDonald, P.C.5
-
12
-
-
0035452345
-
The IL-6 receptor antagonist Sant 7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells
-
Honemann D, Chatterjee M, Savino R, Bommert R, Gramatzki M, Dorken B, Bargou RC (2001) The IL-6 receptor antagonist Sant 7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells. Int J Cancer 93: 674-680
-
(2001)
Int J Cancer
, vol.93
, pp. 674-680
-
-
Honemann, D.1
Chatterjee, M.2
Savino, R.3
Bommert, R.4
Gramatzki, M.5
Dorken, B.6
Bargou, R.C.7
-
13
-
-
0023509164
-
Aromatase activity in normal breast and breast tumour tissues: In vivo and in vitro studies
-
James VHT, McNeill JM, Lai LC, Newton CJ, Ghilchik MW, Reed MJ (1987) Aromatase activity in normal breast and breast tumour tissues: in vivo and in vitro studies. Steroids 50: 269-279
-
(1987)
Steroids
, vol.50
, pp. 269-279
-
-
James, V.H.T.1
McNeill, J.M.2
Lai, L.C.3
Newton, C.J.4
Ghilchik, M.W.5
Reed, M.J.6
-
15
-
-
0025990893
-
Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukaemia
-
Klein B, Wijdenes J, Zhang X-G, Jourdan M, Boiron J-M, Brochier J, Liautard J, Merlin M, Clement C, Mourel-Fournier B, Zhao-Liang L, Mannoni P, Sany J, Baitaille R (1991) Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukaemia. Blood 78: 1198-1204
-
(1991)
Blood
, vol.78
, pp. 1198-1204
-
-
Klein, B.1
Wijdenes, J.2
Zhang, X.-G.3
Jourdan, M.4
Boiron, J.-M.5
Brochier, J.6
Liautard, J.7
Merlin, M.8
Clement, C.9
Mourel-Fournier, B.10
Zhao-Liang, L.11
Mannoni, P.12
Sany, J.13
Baitaille, R.14
-
16
-
-
0034901655
-
Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression
-
Lin D-L, Whitney MC, Yao Z, Keller ET (2001) Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression. Clin Cancer Res 7: 1773-1781
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1773-1781
-
-
Lin, D.-L.1
Whitney, M.C.2
Yao, Z.3
Keller, E.T.4
-
17
-
-
0025875857
-
Interleukin-6 is a prognostic factor in multiple myeloma
-
Ludwig H, Nacnbaur DM, Fritz E, Krainer M, Huber H (1991) Interleukin-6 is a prognostic factor in multiple myeloma. Blood 77: 2794-2795
-
(1991)
Blood
, vol.77
, pp. 2794-2795
-
-
Ludwig, H.1
Nacnbaur, D.M.2
Fritz, E.3
Krainer, M.4
Huber, H.5
-
18
-
-
0028577281
-
Stimulation of aromatase activity in breast fibroblasts by tumour necrosis factor α
-
Macdiarmid F, Wang D, Duncan LJ, Purohit A, Ghilchik MW, Reed MJ (1994) Stimulation of aromatase activity in breast fibroblasts by tumour necrosis factor α. Mol Cell Endocrinol 106: 17-21
-
(1994)
Mol Cell Endocrinol
, vol.106
, pp. 17-21
-
-
Macdiarmid, F.1
Wang, D.2
Duncan, L.J.3
Purohit, A.4
Ghilchik, M.W.5
Reed, M.J.6
-
19
-
-
0027261356
-
Tissue-specific and hormonally controlled alternative promoters regulate aromatase P450 gene expression in human ovary and fetal tissue
-
Mahendroo MS, Mendelson CR, Simpson ER (1993) Tissue-specific and hormonally controlled alternative promoters regulate aromatase P450 gene expression in human ovary and fetal tissue. J Biol Chem 268: 19463-19470
-
(1993)
J Biol Chem
, vol.268
, pp. 19463-19470
-
-
Mahendroo, M.S.1
Mendelson, C.R.2
Simpson, E.R.3
-
20
-
-
0032974458
-
Biology of aromatase inhibitors: Pharmacology/endocrinology within the breast
-
Miller WR (1999) Biology of aromatase inhibitors: pharmacology/endocrinology within the breast. Endocrine Relat Cancer 6: 187-195
-
(1999)
Endocrine Relat Cancer
, vol.6
, pp. 187-195
-
-
Miller, W.R.1
-
21
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6 but not tumour necrosis factor-α, in vivo
-
Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, Klein S, Coppack SW (1997) Subcutaneous adipose tissue releases interleukin-6 but not tumour necrosis factor-α, in vivo. J Clin Endocrinol Metab 82: 4196-4200
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
22
-
-
0035714802
-
Peptide inhibition of cytokine-stimulated aromatase activity in breast tissue fibroblasts
-
Parish D, Purohit A, Singh A, Rosankiewicz J, Ghilchik MW, Reed MJ (2001) Peptide inhibition of cytokine-stimulated aromatase activity in breast tissue fibroblasts. J Steroid Biochem Mol Biol 79: 165-172
-
(2001)
J Steroid Biochem Mol Biol
, vol.79
, pp. 165-172
-
-
Parish, D.1
Purohit, A.2
Singh, A.3
Rosankiewicz, J.4
Ghilchik, M.W.5
Reed, M.J.6
-
23
-
-
0028787970
-
Aromatase activity and interleukin-6 production by normal and malignant breast tissues
-
Purohit A, Ghilchik MW, Duncan LJ, Reed MJ (1995) Aromatase activity and interleukin-6 production by normal and malignant breast tissues. J Clin Endocrinol Metab 80: 3052-3058
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3052-3058
-
-
Purohit, A.1
Ghilchik, M.W.2
Duncan, L.J.3
Reed, M.J.4
-
24
-
-
0026557138
-
Interleukin-1 and interleukin-6 in breast cyst fluid: Their role in regulating aromatase activity in breast cancer cells
-
Reed MJ, Coldham NG, Patel SR, Ghilchik MW, James VHT (1992) Interleukin-1 and interleukin-6 in breast cyst fluid: their role in regulating aromatase activity in breast cancer cells. J Endocrinol 132: R5-R8
-
(1992)
J Endocrinol
, vol.132
-
-
Reed, M.J.1
Coldham, N.G.2
Patel, S.R.3
Ghilchik, M.W.4
James, V.H.T.5
-
25
-
-
0030823667
-
Breast cancer and the role of cytokines in regulating estrogen synthesis: An emerging hypothesis
-
Reed MJ, Purohit MJA (1997) Breast cancer and the role of cytokines in regulating estrogen synthesis: an emerging hypothesis. Endocrine Rev 18: 701-715
-
(1997)
Endocrine Rev
, vol.18
, pp. 701-715
-
-
Reed, M.J.1
Purohit, M.J.A.2
-
26
-
-
0028226196
-
Soluble receptors for cytokines and growth factors: Generation and biological function
-
Rose-John S, Heinrich PC (1994) Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 300: 281-190
-
(1994)
Biochem J
, vol.300
, pp. 281-190
-
-
Rose-John, S.1
Heinrich, P.C.2
-
27
-
-
0029019013
-
Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor α mutated in the predicted gp130-binding interface
-
Salvati AL, Lahm A, Paonessa G, Ciliberto G, Toniatti C (1995) Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor α mutated in the predicted gp130-binding interface. J Biol Chem 270: 12242-12249
-
(1995)
J Biol Chem
, vol.270
, pp. 12242-12249
-
-
Salvati, A.L.1
Lahm, A.2
Paonessa, G.3
Ciliberto, G.4
Toniatti, C.5
-
29
-
-
0012521348
-
Upregulation of the interleukin-6 signal transduction protein (gp130) by interleukin-6 and dexamethasone
-
Schooltink H, Schmitz-Van der Leur H, Heinrich PC, Rose-John S (1992) Upregulation of the interleukin-6 signal transduction protein (gp130) by interleukin-6 and dexamethasone. Eur J Biochem 190: 79-83
-
(1992)
Eur J Biochem
, vol.190
, pp. 79-83
-
-
Schooltink, H.1
Schmitz-Van Der Leur, H.2
Heinrich, P.C.3
Rose-John, S.4
-
30
-
-
0031126176
-
Control of aromatase in breast tumours: The role of the immune system
-
Singh A, Purohit A, Duncan LJ, Mokbel K, Ghilchik MW, Reed MJ (1997) Control of aromatase in breast tumours: the role of the immune system. J Steroid Biochem Mol Biol 61: 185-192
-
(1997)
J Steroid Biochem Mol Biol
, vol.61
, pp. 185-192
-
-
Singh, A.1
Purohit, A.2
Duncan, L.J.3
Mokbel, K.4
Ghilchik, M.W.5
Reed, M.J.6
-
32
-
-
0028880991
-
IL-6sR: Release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis
-
Singh A, Purohit A, Wang DY, Duncan LJ, Ghilchik MW, Reed MJ (1995) IL-6sR: release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis. J Endocrinol 147: R9-R12
-
(1995)
J Endocrinol
, vol.147
-
-
Singh, A.1
Purohit, A.2
Wang, D.Y.3
Duncan, L.J.4
Ghilchik, M.W.5
Reed, M.J.6
-
33
-
-
0024393839
-
Interleukin- 6 triggers the association of its receptor with a possible signal transducer protein
-
Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T, Kishimoto T (1989) Interleukin- 6 triggers the association of its receptor with a possible signal transducer protein. Cell 58: 573-581
-
(1989)
Cell
, vol.58
, pp. 573-581
-
-
Taga, T.1
Hibi, M.2
Hirata, Y.3
Yamasaki, K.4
Yasukawa, K.5
Matsuda, T.6
Hirano, T.7
Kishimoto, T.8
-
34
-
-
0025260903
-
Interleukin- 6: An overview
-
Van Snick J (1990) Interleukin- 6: an overview. Annu Rev Immunol 8: 253-278
-
(1990)
Annu Rev Immunol
, vol.8
, pp. 253-278
-
-
Van Snick, J.1
-
35
-
-
0026497223
-
Increase of plasma IL-6 concentrations with age in healthy subjects
-
Wei J, Xu H, Davies JL, Hemmings GP (1992) Increase of plasma IL-6 concentrations with age in healthy subjects. Life Sci 51: 1953-1956
-
(1992)
Life Sci
, vol.51
, pp. 1953-1956
-
-
Wei, J.1
Xu, H.2
Davies, J.L.3
Hemmings, G.P.4
-
36
-
-
0023951336
-
Synthesis of interleukin 6 (interferon-beta 2/β cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cAMP
-
Zhang Y, Lin J-X, Vilcek J (1988) Synthesis of interleukin 6 (interferon-beta 2/β cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cAMP. J Biol Chem 263: 6177-6182
-
(1988)
J Biol Chem
, vol.263
, pp. 6177-6182
-
-
Zhang, Y.1
Lin, J.-X.2
Vilcek, J.3
-
38
-
-
0028919673
-
Characterisation of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes
-
Zhao Y, Mendelson CR, Simpson ER (1995a) Characterisation of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes. Mol Endocrinol 9: 340-349
-
(1995)
Mol Endocrinol
, vol.9
, pp. 340-349
-
-
Zhao, Y.1
Mendelson, C.R.2
Simpson, E.R.3
-
39
-
-
0029002074
-
Aromatase P450 gene expression in human adipose tissue
-
Zhao Y, Nichols JE, Bulun SE, Mendelson CR, Simpson ER (1995b) Aromatase P450 gene expression in human adipose tissue. J Biol Chem 270: 16449-16457
-
(1995)
J Biol Chem
, vol.270
, pp. 16449-16457
-
-
Zhao, Y.1
Nichols, J.E.2
Bulun, S.E.3
Mendelson, C.R.4
Simpson, E.R.5
|