메뉴 건너뛰기




Volumn 18, Issue 5, 1997, Pages 701-715

Breast cancer and the role of cytokines in regulating estrogen synthesis: An emerging hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYTOKINE; CYTOKINE RECEPTOR; DEXAMETHASONE; ESTROGEN; ESTRONE; GLUCOCORTICOID; GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 6; PRASTERONE; SOMATOMEDIN C; SULFATASE;

EID: 0030823667     PISSN: 0163769X     EISSN: None     Source Type: Journal    
DOI: 10.1210/edrv.18.5.0314     Document Type: Review
Times cited : (125)

References (172)
  • 2
    • 0027182529 scopus 로고
    • Endogenous hormones and breast cancer risk
    • Bernstein L, Ross RK 1993 Endogenous hormones and breast cancer risk. Epidemiol Rev 15:48-65
    • (1993) Epidemiol Rev , vol.15 , pp. 48-65
    • Bernstein, L.1    Ross, R.K.2
  • 3
    • 0000840138 scopus 로고
    • Role of extraglandular estrogen in human endocrinology
    • Greep RO, Astwood EB (eds) Am Physiol Soc, Washington DC
    • Siiteri PK, MacDonald PC 1973 Role of extraglandular estrogen in human endocrinology. In: Greep RO, Astwood EB (eds) Handbook of Physiology. Am Physiol Soc, Washington DC, vol 11, part 1:615-629
    • (1973) Handbook of Physiology , vol.11 , Issue.1 PART , pp. 615-629
    • Siiteri, P.K.1    MacDonald, P.C.2
  • 5
    • 0023509164 scopus 로고
    • Aromatase activity in normal breast and breast tumour tissue: In vivo and in vitro studies
    • James VHT, McNeill JM, Lai LC, Newton CJ, Ghilchik MW, Reed MJ 1987 Aromatase activity in normal breast and breast tumour tissue: in vivo and in vitro studies. Steroids 50:269-279
    • (1987) Steroids , vol.50 , pp. 269-279
    • James, V.H.T.1    McNeill, J.M.2    Lai, L.C.3    Newton, C.J.4    Ghilchik, M.W.5    Reed, M.J.6
  • 6
    • 0020326759 scopus 로고
    • A reassessment of the role of breast tumor aromatase
    • Bradlow HL 1982 A reassessment of the role of breast tumor aromatase. Cancer Res 42 [Suppl]:3382s-3386s
    • (1982) Cancer Res , vol.42 , Issue.SUPPL.
    • Bradlow, H.L.1
  • 7
    • 0017131714 scopus 로고
    • In vivo studies on the metabolism of estrogens by muscle and adipose tissue in normal males
    • Longcope C, Pratt JH, Schneider SH, Fineberg SE 1977 In vivo studies on the metabolism of estrogens by muscle and adipose tissue in normal males. J Clin Endocrinol Metab 45:1134-1145
    • (1977) J Clin Endocrinol Metab , vol.45 , pp. 1134-1145
    • Longcope, C.1    Pratt, J.H.2    Schneider, S.H.3    Fineberg, S.E.4
  • 8
    • 0017283332 scopus 로고
    • Oestradiol synthesis from C19 steroids by human breast cancer
    • Miller WR, Forrest APM 1974 Oestradiol synthesis from C19 steroids by human breast cancer. Br J Cancer 33:16-18
    • (1974) Br J Cancer , vol.33 , pp. 16-18
    • Miller, W.R.1    Forrest, A.P.M.2
  • 11
    • 0002499936 scopus 로고
    • Sulphatase inhibitors: The rationale for the development of a new endocrine therapy
    • Reed MJ, Purohit A 1993 Sulphatase inhibitors: the rationale for the development of a new endocrine therapy. Rev Endocr Relat Cancer 45:51-62
    • (1993) Rev Endocr Relat Cancer , vol.45 , pp. 51-62
    • Reed, M.J.1    Purohit, A.2
  • 13
    • 0023691704 scopus 로고
    • Complete amino acid sequence of human placental 17β-hydroxysteroid dehydrogenase deduced from cDNA
    • Peltoketo H, Isomaa V, Maentausta O, Vihko R 1988 Complete amino acid sequence of human placental 17β-hydroxysteroid dehydrogenase deduced from cDNA. FEBS Lett 239:73-77
    • (1988) FEBS Lett , vol.239 , pp. 73-77
    • Peltoketo, H.1    Isomaa, V.2    Maentausta, O.3    Vihko, R.4
  • 14
    • 0024361957 scopus 로고
    • Characterization of cDNAs for human estradiol 17β-dehydrogenase and assignment of the gene to chromosome: Evidence for two mRNA species with distinct 5′-termini in human placenta
    • Luu-The V, Labrie C, Simard J, Lachance Y, Zhao H-F, Couet J, Leblanc G, Labrie F 1989 Characterization of cDNAs for human estradiol 17β-dehydrogenase and assignment of the gene to chromosome: evidence for two mRNA species with distinct 5′-termini in human placenta. Mol Endocrinol 3:1301-1309
    • (1989) Mol Endocrinol , vol.3 , pp. 1301-1309
    • Luu-The, V.1    Labrie, C.2    Simard, J.3    Lachance, Y.4    Zhao, H.-F.5    Couet, J.6    Leblanc, G.7    Labrie, F.8
  • 15
    • 0006656956 scopus 로고
    • Isolation of a full-length cDNA insert encoding human aromatase cytochrome P450 and its expression in nonsteroidogenic cells
    • Corbin CJ, Graham-Lorence S, McPhaul M, Mason JI, Mendelson CR, Simpson ER 1988 Isolation of a full-length cDNA insert encoding human aromatase cytochrome P450 and its expression in nonsteroidogenic cells. Proc Natl Acad Sci USA 85:8948-8952
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8948-8952
    • Corbin, C.J.1    Graham-Lorence, S.2    McPhaul, M.3    Mason, J.I.4    Mendelson, C.R.5    Simpson, E.R.6
  • 17
    • 0023691843 scopus 로고
    • Cloning of complete cDNA encoding human aromatase: Immunochemical identification and sequence analysis
    • Harada N 1988 Cloning of complete cDNA encoding human aromatase: immunochemical identification and sequence analysis. Biochem Biophys Res Commun 156:725-732
    • (1988) Biochem Biophys Res Commun , vol.156 , pp. 725-732
    • Harada, N.1
  • 18
    • 0024380057 scopus 로고
    • Cloning and expression of human steroid sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells
    • Stein C, Hille A, Seidel J, Rijnbout S, Waheed A, Schmidt B, Geuze H, Figura KV 1989 Cloning and expression of human steroid sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells. J Biol Chem 264:13865-13872
    • (1989) J Biol Chem , vol.264 , pp. 13865-13872
    • Stein, C.1    Hille, A.2    Seidel, J.3    Rijnbout, S.4    Waheed, A.5    Schmidt, B.6    Geuze, H.7    Figura, K.V.8
  • 21
    • 0026569765 scopus 로고
    • 17β-Hydroxysteroid dehydrogenase gene expression in human breast cancer cells: Regulation of expression by a progestin
    • Poutanen M, Moncharmont B, Vihko R 1992 17β-Hydroxysteroid dehydrogenase gene expression in human breast cancer cells: regulation of expression by a progestin. Cancer Res 52:290-294
    • (1992) Cancer Res , vol.52 , pp. 290-294
    • Poutanen, M.1    Moncharmont, B.2    Vihko, R.3
  • 23
    • 0016573396 scopus 로고
    • Breast cancer incidence and nutritional status with particular reference to body weight and height
    • De Waard FW 1975 Breast cancer incidence and nutritional status with particular reference to body weight and height. Cancer Res 35:3351-3356
    • (1975) Cancer Res , vol.35 , pp. 3351-3356
    • De Waard, F.W.1
  • 24
    • 0014203360 scopus 로고
    • Endocrine factors in endometrial carcinoma. A preliminary report
    • Dunn LJ, Bradbury JT 1967 Endocrine factors in endometrial carcinoma. A preliminary report. Am J Obstet Gynecol 97:465-471
    • (1967) Am J Obstet Gynecol , vol.97 , pp. 465-471
    • Dunn, L.J.1    Bradbury, J.T.2
  • 25
    • 0015984830 scopus 로고
    • Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age
    • Hemsell DL, Grodin JM, Brenner PF, Siiteri PK, MacDonald PC 1974 Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab 38:476-479
    • (1974) J Clin Endocrinol Metab , vol.38 , pp. 476-479
    • Hemsell, D.L.1    Grodin, J.M.2    Brenner, P.F.3    Siiteri, P.K.4    MacDonald, P.C.5
  • 26
    • 0021930760 scopus 로고
    • Effects of aging and obesity on aromatase activity of human adipose cells
    • Cleland WH, Mendelson CR, Simpson ER 1985 Effects of aging and obesity on aromatase activity of human adipose cells. J Clin Endocrinol Metab 60:174-177
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 174-177
    • Cleland, W.H.1    Mendelson, C.R.2    Simpson, E.R.3
  • 27
    • 9844238904 scopus 로고
    • The in vitro conversion of androstenedione to oestrone by adipose tissue from normal women and women with endometrial cancer
    • Fioretti P, Martini L, Melis GB, Yen SSC (eds) Serono Symposium No. 39. Academic Press, London
    • Folkerd EJ, Reed MJ, James VHT 1982 The in vitro conversion of androstenedione to oestrone by adipose tissue from normal women and women with endometrial cancer. In: Fioretti P, Martini L, Melis GB, Yen SSC (eds). The Menopause: Clinical, Endocrinological and Pathophysiological Aspects. Serono Symposium No. 39. Academic Press, London, pp 317-323
    • (1982) The Menopause: Clinical, Endocrinological and Pathophysiological Aspects , pp. 317-323
    • Folkerd, E.J.1    Reed, M.J.2    James, V.H.T.3
  • 28
    • 0028044678 scopus 로고
    • Competitive reverse transcriptionpolymerase chain reaction analysis indicates that levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs, and abdomen of women increase with advancing age
    • Bulun SE, Simpson ER 1994 Competitive reverse transcriptionpolymerase chain reaction analysis indicates that levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs, and abdomen of women increase with advancing age. J Clin Endocrinol Metab 78:428-432
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 428-432
    • Bulun, S.E.1    Simpson, E.R.2
  • 30
    • 0001246894 scopus 로고
    • Estrogen formation in stromal cells of adipose tissue of women: Induction by glucocorticoids
    • Simpson ER, Ackerman GE, Smith ME, Mendelson CR 1981 Estrogen formation in stromal cells of adipose tissue of women: induction by glucocorticoids. Proc Natl Acad Sci USA 78:5690-5694
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 5690-5694
    • Simpson, E.R.1    Ackerman, G.E.2    Smith, M.E.3    Mendelson, C.R.4
  • 32
    • 0020788386 scopus 로고
    • Aromatixation of steroids in peripheral tissues
    • Folkerd EJ, James VH 1983 Aromatixation of steroids in peripheral tissues. J Steroid Biochem 19:687-690
    • (1983) J Steroid Biochem , vol.19 , pp. 687-690
    • Folkerd, E.J.1    James, V.H.2
  • 33
    • 0022450496 scopus 로고
    • The effect of glucocorticoids on the in vivo conversion of androstenedione to oestrone
    • Reed MJ, Beranek PA, Franks S, James VH 1986 The effect of glucocorticoids on the in vivo conversion of androstenedione to oestrone. Horm Metab Res 18:635-637
    • (1986) Horm Metab Res , vol.18 , pp. 635-637
    • Reed, M.J.1    Beranek, P.A.2    Franks, S.3    James, V.H.4
  • 34
    • 0023485907 scopus 로고
    • Peripheral aromatization: Studies on controlling factors
    • Longcope C 1987 Peripheral aromatization: studies on controlling factors. Steroids 50:253-267
    • (1987) Steroids , vol.50 , pp. 253-267
    • Longcope, C.1
  • 35
    • 0019840570 scopus 로고
    • The plasma concentration of oestrone sulphate in postmenopausal women: Lack of diurnal variation, effect of ovariectomy, age and weight
    • Noel CT, Reed MJ, Jacobs HS, James VH 1981 The plasma concentration of oestrone sulphate in postmenopausal women: lack of diurnal variation, effect of ovariectomy, age and weight. J Steroid Biochem 14:1101-1105
    • (1981) J Steroid Biochem , vol.14 , pp. 1101-1105
    • Noel, C.T.1    Reed, M.J.2    Jacobs, H.S.3    James, V.H.4
  • 36
    • 0018583335 scopus 로고
    • Estrone sulfate and dehydroepi androsterone sulfate concentrations in normal subjects and men with cirrhosis
    • Franz C, Watson D, Longcope C 1979 Estrone sulfate and dehydroepi androsterone sulfate concentrations in normal subjects and men with cirrhosis. Steroids 34:563-573
    • (1979) Steroids , vol.34 , pp. 563-573
    • Franz, C.1    Watson, D.2    Longcope, C.3
  • 38
    • 0015323450 scopus 로고
    • Estrone sulfate: Production rate and metabolism in man
    • Ruder HJ, Loriaux DL, Lipsett MB 1972 Estrone sulfate: production rate and metabolism in man. J Clin Invest 51:1020-1023
    • (1972) J Clin Invest , vol.51 , pp. 1020-1023
    • Ruder, H.J.1    Loriaux, D.L.2    Lipsett, M.B.3
  • 39
    • 0021149871 scopus 로고
    • In situ estrogen production via estrone sulfatase pathway in breast tumors: Relative importance vs. the aromatase pathway
    • Santner SJ, Feil PD, Santen RJ 1984 In situ estrogen production via estrone sulfatase pathway in breast tumors: relative importance vs. the aromatase pathway. J Clin Endocrinol Metab 59:29-33
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 29-33
    • Santner, S.J.1    Feil, P.D.2    Santen, R.J.3
  • 40
    • 0030200128 scopus 로고    scopus 로고
    • Evidence of in situ estrogen synthesis in nitrosomethylurea-induced rat mammary tumors via the enzyme estrone sulfatase
    • Masamura S, Santner SJ, Santen RJ 1996 Evidence of in situ estrogen synthesis in nitrosomethylurea-induced rat mammary tumors via the enzyme estrone sulfatase. J Steroid Biochem Mol Biol 58:425-430
    • (1996) J Steroid Biochem Mol Biol , vol.58 , pp. 425-430
    • Masamura, S.1    Santner, S.J.2    Santen, R.J.3
  • 42
    • 0021366361 scopus 로고
    • 17β Hydroxysteroid dehydrogenase activity in breast fat from women with benign and malignant breast tumours
    • Beranek PA, Folkerd EJ, Ghilchik MW, James VHT 1984 17β Hydroxysteroid dehydrogenase activity in breast fat from women with benign and malignant breast tumours. Clin Endocrinol (Oxf) 20:205-212
    • (1984) Clin Endocrinol (Oxf) , vol.20 , pp. 205-212
    • Beranek, P.A.1    Folkerd, E.J.2    Ghilchik, M.W.3    James, V.H.T.4
  • 43
    • 0016836195 scopus 로고
    • Determinations of hormonal steroid concentrations in biological extracts by high resolution mass fragmentography
    • Millington DS 1975 Determinations of hormonal steroid concentrations in biological extracts by high resolution mass fragmentography. J Steroid Biochem 6:239-245
    • (1975) J Steroid Biochem , vol.6 , pp. 239-245
    • Millington, D.S.1
  • 44
    • 0021069852 scopus 로고
    • The relationship between 17β-hydroxysteroid dehydrogenase activity and oestrogen concentrations in human breast tumours and in normal breast tissue
    • Bonney RC, Reed MJ, Davidson K, Beranek PA, James VH 1983 The relationship between 17β-hydroxysteroid dehydrogenase activity and oestrogen concentrations in human breast tumours and in normal breast tissue. Clin Endocrinol (Oxf) 19:727-739
    • (1983) Clin Endocrinol (Oxf) , vol.19 , pp. 727-739
    • Bonney, R.C.1    Reed, M.J.2    Davidson, K.3    Beranek, P.A.4    James, V.H.5
  • 45
    • 0022642042 scopus 로고
    • Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women
    • Vermeulen A, Deslypere JP, Paridaens R, Leclerq G, Roy F, Henson JC 1986 Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women. Eur J Cancer 22:515-525
    • (1986) Eur J Cancer , vol.22 , pp. 515-525
    • Vermeulen, A.1    Deslypere, J.P.2    Paridaens, R.3    Leclerq, G.4    Roy, F.5    Henson, J.C.6
  • 47
    • 0024891561 scopus 로고
    • Endogenous oestrogens and androgens in normal and malignant endometrial and mammary tissues
    • Thijssen JHH, Blankenstein MA 1989 Endogenous oestrogens and androgens in normal and malignant endometrial and mammary tissues. Eur J Cancer Clin Oncol 25:1953-1959
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 1953-1959
    • Thijssen, J.H.H.1    Blankenstein, M.A.2
  • 48
    • 0023508938 scopus 로고
    • Estrogens in tissues: Uptake from the peripheral circulation or local production
    • Thijssen JHH, Blankenstein MA, Miller WR, Milewicz A 1987 Estrogens in tissues: uptake from the peripheral circulation or local production. Steroids 50:297-306
    • (1987) Steroids , vol.50 , pp. 297-306
    • Thijssen, J.H.H.1    Blankenstein, M.A.2    Miller, W.R.3    Milewicz, A.4
  • 50
  • 51
    • 0019346536 scopus 로고
    • Endogenous oestradiol-17β concentration in breast tumours determined by mass fragmentography and by radioimmunoassay: Relationship to receptor content
    • Edery M, Goussard J, Dehennin L, Scholler R, Reiffsteck J, Drosdowsky MA 1981 Endogenous oestradiol-17β concentration in breast tumours determined by mass fragmentography and by radioimmunoassay: relationship to receptor content. Eur J Cancer 17:115-120
    • (1981) Eur J Cancer , vol.17 , pp. 115-120
    • Edery, M.1    Goussard, J.2    Dehennin, L.3    Scholler, R.4    Reiffsteck, J.5    Drosdowsky, M.A.6
  • 52
    • 0018509037 scopus 로고
    • Relationship between estrogen receptors, 17β hydroxysteroid dehydrogenase and estrogen content in human breast cancer
    • Abul-Hajj YJ 1979 Relationship between estrogen receptors, 17β hydroxysteroid dehydrogenase and estrogen content in human breast cancer. Steroids 34:217-225
    • (1979) Steroids , vol.34 , pp. 217-225
    • Abul-Hajj, Y.J.1
  • 53
    • 0024419217 scopus 로고
    • In situ oestrone synthesis in normal breast and breast tumour tissue: Effect of treatment with 4-hydroxyandrostenedione
    • Reed MJ, Owen AM, Lai LC, Coldham NG, Ghilchik MW, Shaikh NA, James VHT 1989 In situ oestrone synthesis in normal breast and breast tumour tissue: effect of treatment with 4-hydroxyandrostenedione. Int J Cancer 44:233-237
    • (1989) Int J Cancer , vol.44 , pp. 233-237
    • Reed, M.J.1    Owen, A.M.2    Lai, L.C.3    Coldham, N.G.4    Ghilchik, M.W.5    Shaikh, N.A.6    James, V.H.T.7
  • 54
    • 0025992953 scopus 로고
    • Regulation of oestradiol 17β hydroxysteroid dehydrogenase in breast tissues: The role of growth factors
    • Reed MJ, Singh A, Ghilchik MW, Coldham NG, Purohit A 1991 Regulation of oestradiol 17β hydroxysteroid dehydrogenase in breast tissues: the role of growth factors. J Steroid Biochem Mol Biol 39:791-798
    • (1991) J Steroid Biochem Mol Biol , vol.39 , pp. 791-798
    • Reed, M.J.1    Singh, A.2    Ghilchik, M.W.3    Coldham, N.G.4    Purohit, A.5
  • 55
    • 0022378125 scopus 로고
    • The relationship between 17β-hydroxysteroid dehydrogenase activity and breast tumour site and size
    • Beranek PA, Folkerd E, Newton CJ, Reed MJ, Ghilchik MW, James VHT 1985 The relationship between 17β-hydroxysteroid dehydrogenase activity and breast tumour site and size. Int J Cancer 36:685-687
    • (1985) Int J Cancer , vol.36 , pp. 685-687
    • Beranek, P.A.1    Folkerd, E.2    Newton, C.J.3    Reed, M.J.4    Ghilchik, M.W.5    James, V.H.T.6
  • 56
    • 0022887575 scopus 로고
    • The role of tissue steroids in regulating aromatase and oestradiol 17β-hydroxysteroid dehydrogenase activities in breast and endometrial cancer
    • James VHT, McNeill JM, Beranek PA, Bonney RC, Reed MJ 1986 The role of tissue steroids in regulating aromatase and oestradiol 17β-hydroxysteroid dehydrogenase activities in breast and endometrial cancer. J Steroid Biochem 25:787-790
    • (1986) J Steroid Biochem , vol.25 , pp. 787-790
    • James, V.H.T.1    McNeill, J.M.2    Beranek, P.A.3    Bonney, R.C.4    Reed, M.J.5
  • 57
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen within the breast
    • Miller WR, O'Neill JS 1987 The importance of local synthesis of estrogen within the breast. Steroids 50:537-547
    • (1987) Steroids , vol.50 , pp. 537-547
    • Miller, W.R.1    O'Neill, J.S.2
  • 58
    • 0023831082 scopus 로고
    • Aromatase activity in adipose tissue from breast quadrants: A link with tumour site
    • O'Neill JS, Elton RA, Miller WR 1988 Aromatase activity in adipose tissue from breast quadrants: a link with tumour site. Br Med J 296:741-743
    • (1988) Br Med J , vol.296 , pp. 741-743
    • O'Neill, J.S.1    Elton, R.A.2    Miller, W.R.3
  • 59
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen synthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • Bulun SE, Price TM, Aitken J, Mahendroo MS, Simpson ER 1993 A link between breast cancer and local estrogen synthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J Clin Endocrinol Metal 77:1622-1628
    • (1993) J Clin Endocrinol Metal , vol.77 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Aitken, J.3    Mahendroo, M.S.4    Simpson, E.R.5
  • 62
    • 0028984883 scopus 로고
    • Oestrone sulphatase activity in normal and malignant breast tissues: Relationship with tumour location
    • Chapman O, Purohit A, Wang DY, Ghilchik MW, Reed MJ 1995 Oestrone sulphatase activity in normal and malignant breast tissues: relationship with tumour location. Anticancer Res 15:1467-1472
    • (1995) Anticancer Res , vol.15 , pp. 1467-1472
    • Chapman, O.1    Purohit, A.2    Wang, D.Y.3    Ghilchik, M.W.4    Reed, M.J.5
  • 63
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL 1996 Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 56:4625-4629
    • (1996) Cancer Res , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 64
    • 0028302746 scopus 로고
    • Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders
    • Sasano H, Nagura H, Harada N, Goukon Y, Kimura M 1994 Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Hum Pathol 25:530-535
    • (1994) Hum Pathol , vol.25 , pp. 530-535
    • Sasano, H.1    Nagura, H.2    Harada, N.3    Goukon, Y.4    Kimura, M.5
  • 67
    • 0029941512 scopus 로고    scopus 로고
    • Expression of aromatase protein and mRNA in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancer
    • Lu Q, Nakmura J, Savinov A, Yue W, Weisz J, Dabbs DJ, Wolz G, Brodie A 1996 Expression of aromatase protein and mRNA in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancer. Endocrinology 137:3061-3068
    • (1996) Endocrinology , vol.137 , pp. 3061-3068
    • Lu, Q.1    Nakmura, J.2    Savinov, A.3    Yue, W.4    Weisz, J.5    Dabbs, D.J.6    Wolz, G.7    Brodie, A.8
  • 69
    • 0026557238 scopus 로고
    • Immunological analysis of 17β-hydroxysteroid dehydrogenase in benign and malignant human breast tissue
    • Poutanen M, Isomaa V, Lehto V-P, Vihko R 1992 Immunological analysis of 17β-hydroxysteroid dehydrogenase in benign and malignant human breast tissue. Int J Cancer 50:386-390
    • (1992) Int J Cancer , vol.50 , pp. 386-390
    • Poutanen, M.1    Isomaa, V.2    Lehto, V.-P.3    Vihko, R.4
  • 70
    • 0022539019 scopus 로고
    • The effect of epidermal growth factor, transforming growth factor α and breast tumour homogenates on the activity of oestradiol 17β-hydroxysteroid dehydrogenase in cultured adipose tissue
    • McNeill JM, Reed MJ, Beranek PA, Newton CJ, Ghilchik MW, James VHT 1986 The effect of epidermal growth factor, transforming growth factor α and breast tumour homogenates on the activity of oestradiol 17β-hydroxysteroid dehydrogenase in cultured adipose tissue. Cancer Lett 31:213-219
    • (1986) Cancer Lett , vol.31 , pp. 213-219
    • McNeill, J.M.1    Reed, M.J.2    Beranek, P.A.3    Newton, C.J.4    Ghilchik, M.W.5    James, V.H.T.6
  • 71
    • 0024576737 scopus 로고
    • The effect of breast tumour and normal tissue cytosols on oestradiol 17β-hydroxysteroid dehydrogenase activity
    • Singh A, Reed MJ, Ghilchik MW, James VHT 1989 The effect of breast tumour and normal tissue cytosols on oestradiol 17β-hydroxysteroid dehydrogenase activity. Cancer Lett 44:45-48
    • (1989) Cancer Lett , vol.44 , pp. 45-48
    • Singh, A.1    Reed, M.J.2    Ghilchik, M.W.3    James, V.H.T.4
  • 75
    • 0027227922 scopus 로고
    • Benign breast diseases, carcinoma in situ, and breast cancer risk
    • Bodian CA 1993 Benign breast diseases, carcinoma in situ, and breast cancer risk. Epidemiol Rev 15:177-187
    • (1993) Epidemiol Rev , vol.15 , pp. 177-187
    • Bodian, C.A.1
  • 76
    • 0025637656 scopus 로고
    • Effect of breast cyst fluid as oestrogen 17-oxidoreductase activity in MCF-7 breast cancer cells
    • Lai LC, Coldham NG, Islam S, Reed MJ, Ghilchik MW, James VHT 1990 Effect of breast cyst fluid as oestrogen 17-oxidoreductase activity in MCF-7 breast cancer cells. Cancer Lett 55:165-169
    • (1990) Cancer Lett , vol.55 , pp. 165-169
    • Lai, L.C.1    Coldham, N.G.2    Islam, S.3    Reed, M.J.4    Ghilchik, M.W.5    James, V.H.T.6
  • 77
    • 0028132723 scopus 로고
    • The effect of gross cystic disease fluid proteins on oestrogen synthesis in breast cancer cells
    • Duncan LJ, Robinson GV, Ghilchik MW, Reed MJ 1994 The effect of gross cystic disease fluid proteins on oestrogen synthesis in breast cancer cells. Endocr Relat Cancer 2:27-35
    • (1994) Endocr Relat Cancer , vol.2 , pp. 27-35
    • Duncan, L.J.1    Robinson, G.V.2    Ghilchik, M.W.3    Reed, M.J.4
  • 78
    • 0026557138 scopus 로고
    • Interleukin-1 and interleukin-6 in breast cyst fluid: Their role in regulating aromatase activity in breast cancer cells
    • Reed MJ, Coldham NG, Patel SR, Ghilchik MW, James VHT 1992 Interleukin-1 and interleukin-6 in breast cyst fluid: their role in regulating aromatase activity in breast cancer cells. J Endocrinol 132:R5-R8
    • (1992) J Endocrinol , vol.132
    • Reed, M.J.1    Coldham, N.G.2    Patel, S.R.3    Ghilchik, M.W.4    James, V.H.T.5
  • 79
    • 9844255266 scopus 로고
    • The regulation of estrogen synthesis in breast cells by growth factors, breast cyst fluid and breast tumour-derived factors
    • Reed MJ, Singh A, Coldham NG, Purohit A, Ghilchik MW, James VHT 1992 The regulation of estrogen synthesis in breast cells by growth factors, breast cyst fluid and breast tumour-derived factors. Cancer Detect Prev 16 [Suppl]:S61-S64
    • (1992) Cancer Detect Prev , vol.16 , Issue.SUPPL.
    • Reed, M.J.1    Singh, A.2    Coldham, N.G.3    Purohit, A.4    Ghilchik, M.W.5    James, V.H.T.6
  • 80
    • 0025853310 scopus 로고
    • Insulin-like growth factor I and insulin-like growth factor II stimulate oestradiol 17β-hydroxysteroid dehydrogenase activity in breast cancer cells
    • Singh A, Reed MJ 1991 Insulin-like growth factor I and insulin-like growth factor II stimulate oestradiol 17β-hydroxysteroid dehydrogenase activity in breast cancer cells. J Endocr 129:R5-R8
    • (1991) J Endocr , vol.129
    • Singh, A.1    Reed, M.J.2
  • 81
    • 0026514012 scopus 로고
    • Identification of albumin in breast tumour cytosol as a factor involved in the stimulation of oestradiol 17β-hydroxysteroid dehydrogenase (reductive) activity
    • Singh A, Ghilchik MW, Patel SR, Blench I, Morris HR, Reed MJ 1992 Identification of albumin in breast tumour cytosol as a factor involved in the stimulation of oestradiol 17β-hydroxysteroid dehydrogenase (reductive) activity. Mol Cell Endocrinol 83:85-92
    • (1992) Mol Cell Endocrinol , vol.83 , pp. 85-92
    • Singh, A.1    Ghilchik, M.W.2    Patel, S.R.3    Blench, I.4    Morris, H.R.5    Reed, M.J.6
  • 82
    • 0026751207 scopus 로고
    • Synergistic interaction of growth factors and albumin in regulating oestrogen synthesis in breast cancer cells
    • Singh A, Blench I, Morris HR, Savoy L-A, Reed MJ 1992 Synergistic interaction of growth factors and albumin in regulating oestrogen synthesis in breast cancer cells. Mol Cell Endocrinol 85:165-173
    • (1992) Mol Cell Endocrinol , vol.85 , pp. 165-173
    • Singh, A.1    Blench, I.2    Morris, H.R.3    Savoy, L.-A.4    Reed, M.J.5
  • 83
    • 0023408920 scopus 로고
    • Evidence of interleukin-1-like activity associated with bovine serum albumin
    • Soto T 1987 Evidence of interleukin-1-like activity associated with bovine serum albumin. J Clin Lab Immunol 24:39-43
    • (1987) J Clin Lab Immunol , vol.24 , pp. 39-43
    • Soto, T.1
  • 84
    • 0027441851 scopus 로고
    • Stimulation of IL-6 and prostaglandin E2 secretion from peritoneal macrophages by polymers of albumin
    • Shacter E, Arzadon GK, William JA 1993 Stimulation of IL-6 and prostaglandin E2 secretion from peritoneal macrophages by polymers of albumin. Blood 82:2853-2864
    • (1993) Blood , vol.82 , pp. 2853-2864
    • Shacter, E.1    Arzadon, G.K.2    William, J.A.3
  • 85
    • 0028170733 scopus 로고
    • Oncostatin M, interleukin-2, interleukin-6 and interleukin-8 in breast cyst fluid
    • Lai LC, Kadory S, Siraj A, Lennard TWJ 1994 Oncostatin M, interleukin-2, interleukin-6 and interleukin-8 in breast cyst fluid, Int J Cancer 59:369-372
    • (1994) Int J Cancer , vol.59 , pp. 369-372
    • Lai, L.C.1    Kadory, S.2    Siraj, A.3    Lennard, T.W.J.4
  • 87
    • 0005454789 scopus 로고
    • Paracrine influence of human breast stromal fibroblasts on breast epithelial cells: Secretion of a polypeptide which stimulates reductive 17β-oestradiol dehydrogenase activity
    • Adams EF, Newton CJ, Tait GH, Braunsberg H, Reed MJ, James VHT 1988 Paracrine influence of human breast stromal fibroblasts on breast epithelial cells: secretion of a polypeptide which stimulates reductive 17β-oestradiol dehydrogenase activity. Int J Cancer 42:119-122
    • (1988) Int J Cancer , vol.42 , pp. 119-122
    • Adams, E.F.1    Newton, C.J.2    Tait, G.H.3    Braunsberg, H.4    Reed, M.J.5    James, V.H.T.6
  • 88
    • 0025866941 scopus 로고
    • Interleukin 6 is secreted by breast fibroblasts and stimulates 17β-oestradiol oxidoreductase activity in MCF-7 cells: Possible paracrine regulation of 17β-oestradiol levels
    • Adams EF, Rafferty B, White MC 1991 Interleukin 6 is secreted by breast fibroblasts and stimulates 17β-oestradiol oxidoreductase activity in MCF-7 cells: possible paracrine regulation of 17β-oestradiol levels. Int J Cancer 49:118-121
    • (1991) Int J Cancer , vol.49 , pp. 118-121
    • Adams, E.F.1    Rafferty, B.2    White, M.C.3
  • 89
    • 0028322040 scopus 로고
    • The interaction of cytokines in regulating oestradiol 17β-hydroxysteroid dehydrogenase activity in MCF-7 cells
    • Duncan LJ, Coldham NG, Reed MJ 1994 The interaction of cytokines in regulating oestradiol 17β-hydroxysteroid dehydrogenase activity in MCF-7 cells. J Steroid Biochem Mol Biol 49:63-68
    • (1994) J Steroid Biochem Mol Biol , vol.49 , pp. 63-68
    • Duncan, L.J.1    Coldham, N.G.2    Reed, M.J.3
  • 90
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor α: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegleman BM 1993 Adipose expression of tumor necrosis factor α: direct role in obesity-linked insulin resistance. Science 259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegleman, B.M.3
  • 95
    • 0028273455 scopus 로고
    • The human breast cancer cell line MDA-MB-231 produces an aromatase stimulating activity
    • Schmidt M, Loffler G 1994 The human breast cancer cell line MDA-MB-231 produces an aromatase stimulating activity. Eur J Cell Biol 63:96-101
    • (1994) Eur J Cell Biol , vol.63 , pp. 96-101
    • Schmidt, M.1    Loffler, G.2
  • 96
    • 0030034383 scopus 로고    scopus 로고
    • Interleukin-6 acts as a paracrine growth factor in human mammary carcinoma cell lines
    • Chiu JJ, Sgagias MK, Cowan KH 1996 Interleukin-6 acts as a paracrine growth factor in human mammary carcinoma cell lines. Clin Cancer Res 2:215-221
    • (1996) Clin Cancer Res , vol.2 , pp. 215-221
    • Chiu, J.J.1    Sgagias, M.K.2    Cowan, K.H.3
  • 97
    • 0028880991 scopus 로고
    • IL-6 sR: Release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis
    • Singh A, Purohit A, Wang DY, Duncan LJ, Ghilchik MW, Reed MJ 1995 IL-6 sR: release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis. J Endocrinol 147:R9-R12
    • (1995) J Endocrinol , vol.147
    • Singh, A.1    Purohit, A.2    Wang, D.Y.3    Duncan, L.J.4    Ghilchik, M.W.5    Reed, M.J.6
  • 98
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: Generation and biological function
    • Rose-John S, Heinrich PC 1994 Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 300: 281-290
    • (1994) Biochem J , vol.300 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 99
    • 0030063533 scopus 로고    scopus 로고
    • Soluble cytokine receptors
    • Heaney ML, Golde DW 1996 Soluble cytokine receptors. Blood 87:847-857
    • (1996) Blood , vol.87 , pp. 847-857
    • Heaney, M.L.1    Golde, D.W.2
  • 100
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T, Akira S, Narazaki M, Taga T 1995 Interleukin-6 family of cytokines and gp130. Blood 86:1243-1254
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 101
  • 102
    • 0024458160 scopus 로고
    • Soluble cytokine receptors are present in normal human urine
    • Novick D, Engelmann H, Wallach D, Rubinstein M 1989 Soluble cytokine receptors are present in normal human urine. J Exp Med 170:1409-1414
    • (1989) J Exp Med , vol.170 , pp. 1409-1414
    • Novick, D.1    Engelmann, H.2    Wallach, D.3    Rubinstein, M.4
  • 106
    • 0028087834 scopus 로고
    • Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism
    • Horiuchi S, Koyanagi Y, Zhou Y, Miyamoto H, Tanaka Y, Waki M, Matsumoto A, Yamamoto M, Yamamoto N 1994 Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism. Eur J Immunol 24:1945-1948
    • (1994) Eur J Immunol , vol.24 , pp. 1945-1948
    • Horiuchi, S.1    Koyanagi, Y.2    Zhou, Y.3    Miyamoto, H.4    Tanaka, Y.5    Waki, M.6    Matsumoto, A.7    Yamamoto, M.8    Yamamoto, N.9
  • 107
    • 0026782577 scopus 로고
    • Complex of soluble human interleukin-6-receptor/IL-6 up-regulates expression of acute phase proteins
    • Mackiewicz A, Schooltink H, Heinrich PC, Rose-John S 1992 Complex of soluble human interleukin-6-receptor/IL-6 up-regulates expression of acute phase proteins. J Immunol 149:2021-2027
    • (1992) J Immunol , vol.149 , pp. 2021-2027
    • Mackiewicz, A.1    Schooltink, H.2    Heinrich, P.C.3    Rose-John, S.4
  • 108
    • 0026483986 scopus 로고
    • Enhancement of IL-6 cytostatic effect on human breast carcinoma cells by IL-6 soluble receptor
    • Novick D, Schulman LM, Chen L, Revel M 1992 Enhancement of IL-6 cytostatic effect on human breast carcinoma cells by IL-6 soluble receptor. Cytokine 4:6-11
    • (1992) Cytokine , vol.4 , pp. 6-11
    • Novick, D.1    Schulman, L.M.2    Chen, L.3    Revel, M.4
  • 112
    • 0026544579 scopus 로고
    • Upregulation of the interleukin-6 signal transduction protein (gp1301) by interleukin-6 and dexamethasone in the Hep G2 cells
    • Schooltink H, Schmitz-Van der Leur H, Heinrich PC, Rose-John S 1992 Upregulation of the interleukin-6 signal transduction protein (gp1301) by interleukin-6 and dexamethasone in the Hep G2 cells. FEBS Lett 297:263-265
    • (1992) FEBS Lett , vol.297 , pp. 263-265
    • Schooltink, H.1    Schmitz-Van der Leur, H.2    Heinrich, P.C.3    Rose-John, S.4
  • 113
    • 0026663446 scopus 로고
    • Enhancement of IL-6 receptor β chain (gp130) expression by IL-6, IL-1 and TNFα in human epithelial cells
    • Snyers L, Content J 1992 Enhancement of IL-6 receptor β chain (gp130) expression by IL-6, IL-1 and TNFα in human epithelial cells. Biochem Biophys Res Commun 185:902-908
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 902-908
    • Snyers, L.1    Content, J.2
  • 114
    • 0027323684 scopus 로고
    • Interactive effects of interleukin-6, 17β-estradiol and progesterone on growth and 17β-hydroxy steroid dehydrogenase activity in human breast carcinoma cells
    • Speirs V, Adams EF, Rafferty B, White MC 1993 Interactive effects of interleukin-6, 17β-estradiol and progesterone on growth and 17β-hydroxy steroid dehydrogenase activity in human breast carcinoma cells. J Steroid Biochem Mol Biol 46:11-15
    • (1993) J Steroid Biochem Mol Biol , vol.46 , pp. 11-15
    • Speirs, V.1    Adams, E.F.2    Rafferty, B.3    White, M.C.4
  • 115
    • 0027368341 scopus 로고
    • The anti-estrogen tamoxifen blocks the stimulatory effects of interleukin-6 on 17β-hydroxysteroid dehydrogenase activity in MCF-7 cells
    • Speirs V, Adams EF, White MC 1993 The anti-estrogen tamoxifen blocks the stimulatory effects of interleukin-6 on 17β-hydroxysteroid dehydrogenase activity in MCF-7 cells. J Steroid Biochem Mol Biol 46:605-611
    • (1993) J Steroid Biochem Mol Biol , vol.46 , pp. 605-611
    • Speirs, V.1    Adams, E.F.2    White, M.C.3
  • 117
    • 0347923403 scopus 로고
    • On the cause of the localization of secondary tumors at points of injury
    • Jones F, Rous P 1914 On the cause of the localization of secondary tumors at points of injury. J Exp Med 20:404-412
    • (1914) J Exp Med , vol.20 , pp. 404-412
    • Jones, F.1    Rous, P.2
  • 118
    • 0024198180 scopus 로고
    • Preferential growth of blood-borne cancer cells at sites of trauma - A growth promoting role of macrophages
    • Alexander P, Murphy P, Skipper D 1988 Preferential growth of blood-borne cancer cells at sites of trauma - a growth promoting role of macrophages. Adv Exp Med Biol 233:245-251
    • (1988) Adv Exp Med Biol , vol.233 , pp. 245-251
    • Alexander, P.1    Murphy, P.2    Skipper, D.3
  • 120
    • 8544224030 scopus 로고
    • Effect of treatment with 4-hydroxyandrostenedione on the peripheral conversion of androstenedione to estrone and in vitro tumor aromatase activity in postmenopausal breast cancer patients
    • Reed MJ, Lai LC, Owen AM, Singh A, Coldham NG, Purohit A, Ghilchik MW, Shaikh NA, James VHT 1989 Effect of treatment with 4-hydroxyandrostenedione on the peripheral conversion of androstenedione to estrone and in vitro tumor aromatase activity in postmenopausal breast cancer patients. Cancer Res 49:1306-1311
    • (1989) Cancer Res , vol.49 , pp. 1306-1311
    • Reed, M.J.1    Lai, L.C.2    Owen, A.M.3    Singh, A.4    Coldham, N.G.5    Purohit, A.6    Ghilchik, M.W.7    Shaikh, N.A.8    James, V.H.T.9
  • 121
    • 0027940222 scopus 로고
    • The role of aromatase in breast tumors
    • Reed MJ 1994 The role of aromatase in breast tumors. Breast Cancer Res Treat 30:7-17
    • (1994) Breast Cancer Res Treat , vol.30 , pp. 7-17
    • Reed, M.J.1
  • 122
    • 0026075029 scopus 로고
    • Concentrations of oestrone and 4-hydroxyandrostenedione in malignant and normal breast tissues
    • Reed MJ, Aherne GW, Ghilchik MW, Patel S, Chakraborty J 1991 Concentrations of oestrone and 4-hydroxyandrostenedione in malignant and normal breast tissues. Int J Cancer 49:562-565
    • (1991) Int J Cancer , vol.49 , pp. 562-565
    • Reed, M.J.1    Aherne, G.W.2    Ghilchik, M.W.3    Patel, S.4    Chakraborty, J.5
  • 123
    • 0002557099 scopus 로고
    • In vitro and in vivo effects of 4-hydroxyandrostenedione on steroid and tumour metabolism
    • Miller WR 1991 In vitro and in vivo effects of 4-hydroxyandrostenedione on steroid and tumour metabolism. Int Cong Symp Ser 180:45-49
    • (1991) Int Cong Symp Ser , vol.180 , pp. 45-49
    • Miller, W.R.1
  • 124
    • 0023836831 scopus 로고
    • Macrophages in human breast disease: A quantitative immunohistochemical study
    • Kelly PM, Davison RS, Bliss E, McGee JO 1988 Macrophages in human breast disease: a quantitative immunohistochemical study. Br J Cancer 57:174-177
    • (1988) Br J Cancer , vol.57 , pp. 174-177
    • Kelly, P.M.1    Davison, R.S.2    Bliss, E.3    McGee, J.O.4
  • 127
    • 0028052968 scopus 로고
    • Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines
    • Baggiolini M, Dewald B, Moser B 1994 Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 55:97-179
    • (1994) Adv Immunol , vol.55 , pp. 97-179
    • Baggiolini, M.1    Dewald, B.2    Moser, B.3
  • 128
    • 0025141464 scopus 로고
    • Human monocyte chemoattractant protein-1 (MCP-1)
    • Leonard EJ, Yoshimura T 1990 Human monocyte chemoattractant protein-1 (MCP-1). Immunol Today 11:97-101
    • (1990) Immunol Today , vol.11 , pp. 97-101
    • Leonard, E.J.1    Yoshimura, T.2
  • 129
    • 0029099616 scopus 로고
    • Chemoattractant signaling and leukocyte activation
    • Bokoch GM 1995 Chemoattractant signaling and leukocyte activation. Blood 86:1649-1660
    • (1995) Blood , vol.86 , pp. 1649-1660
    • Bokoch, G.M.1
  • 130
    • 9844257258 scopus 로고
    • IFNα and IFN-γ can affect both monocytes and tumor cells to modulate monocyte-mediated cytotoxicity
    • Webb DSA, Gerrard TL 1990 IFNα and IFN-γ can affect both monocytes and tumor cells to modulate monocyte-mediated cytotoxicity. Proc Natl Acad Sci USA 144:3443-3648
    • (1990) Proc Natl Acad Sci USA , vol.144 , pp. 3443-3648
    • Webb, D.S.A.1    Gerrard, T.L.2
  • 131
    • 9844261935 scopus 로고    scopus 로고
    • IL-6 and IL-8 production by primary cultures of breast epithelial and stromal cells of normal and neoplastic origin
    • Abstract P11
    • Green AR, White MC, Speirs V 1996 IL-6 and IL-8 production by primary cultures of breast epithelial and stromal cells of normal and neoplastic origin. J Endocrinol 148 [Suppl]: Abstract P11
    • (1996) J Endocrinol , vol.148 , Issue.SUPPL.
    • Green, A.R.1    White, M.C.2    Speirs, V.3
  • 132
    • 0029586602 scopus 로고
    • Three-component model of oestrogen formation and regulation of intratumoural oestrogen pool in breast neoplasms
    • Berstein LM, Santen RJ, Santner SJ 1995 Three-component model of oestrogen formation and regulation of intratumoural oestrogen pool in breast neoplasms. Med Hypotheses 45:588-590
    • (1995) Med Hypotheses , vol.45 , pp. 588-590
    • Berstein, L.M.1    Santen, R.J.2    Santner, S.J.3
  • 134
    • 0025923025 scopus 로고
    • Human Th1 and Th2 subsets: Doubt no more
    • Romagnani S 1992 Human Th1 and Th2 subsets: doubt no more. Immunol Today 12:256-257
    • (1992) Immunol Today , vol.12 , pp. 256-257
    • Romagnani, S.1
  • 135
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A 1996 Functional diversity of helper T lymphocytes. Nature 383:787-793
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 137
    • 0025284590 scopus 로고
    • Regulation of murine lymphokine production in vivo. II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells
    • Daynes RA, Dudley DJ, Araneo BA 1990 Regulation of murine lymphokine production in vivo. II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells. Eur J Immunol 20:793-803
    • (1990) Eur J Immunol , vol.20 , pp. 793-803
    • Daynes, R.A.1    Dudley, D.J.2    Araneo, B.A.3
  • 138
    • 0028048169 scopus 로고
    • Hormones, peripherally activated prohormones and regulation of Th1/Th2 balance
    • Rook GAW, Hernandez-Pando R, Lightman S 1994 Hormones, peripherally activated prohormones and regulation of Th1/Th2 balance. Immunol Today 15:301-303
    • (1994) Immunol Today , vol.15 , pp. 301-303
    • Rook, G.A.W.1    Hernandez-Pando, R.2    Lightman, S.3
  • 139
    • 0026497223 scopus 로고
    • Increase of plasma IL-6 concentrations with age in healthy subjects
    • Wei J, Xu H, Davies JL, Hemmings GP 1992 Increase of plasma IL-6 concentrations with age in healthy subjects. Life Sci 51:1953-1956
    • (1992) Life Sci , vol.51 , pp. 1953-1956
    • Wei, J.1    Xu, H.2    Davies, J.L.3    Hemmings, G.P.4
  • 141
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich N, Brind JL, Rizer RL, Vogelman JN 1984 Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 59: 551-555
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.N.4
  • 143
    • 0028824816 scopus 로고
    • Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes
    • Okabe T, Haji M, Takayanagi R, Adachi M, Imasaki K, Kurimoto F, Watanabe T, Nawata H 1995 Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes. J Clin Endocrinol Metab 80:2993-2996
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2993-2996
    • Okabe, T.1    Haji, M.2    Takayanagi, R.3    Adachi, M.4    Imasaki, K.5    Kurimoto, F.6    Watanabe, T.7    Nawata, H.8
  • 144
    • 0024652821 scopus 로고
    • Peripheral oestrogen synthesis in man: Its regulation and possible physiological significance
    • Hodgins M 1989 Peripheral oestrogen synthesis in man: its regulation and possible physiological significance. J Endocrinol 121:1-3
    • (1989) J Endocrinol , vol.121 , pp. 1-3
    • Hodgins, M.1
  • 148
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegleman BM 1995 Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 95:2409-2415
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegleman, B.M.5
  • 149
    • 0014199899 scopus 로고
    • Abnormal urinary steroid excretion and subsequent breast cancer
    • Bulbrook RD, Hayward JL 1967 Abnormal urinary steroid excretion and subsequent breast cancer. Lancet 1:519-522
    • (1967) Lancet , vol.1 , pp. 519-522
    • Bulbrook, R.D.1    Hayward, J.L.2
  • 150
    • 0002760543 scopus 로고
    • The discriminant function test: A marker of Th1/Th2 cytokine secretion and breast tumour oestrogen synthesis
    • Reed MJ 1995 The discriminant function test: a marker of Th1/Th2 cytokine secretion and breast tumour oestrogen synthesis. Mol Med Today 1:98-103
    • (1995) Mol Med Today , vol.1 , pp. 98-103
    • Reed, M.J.1
  • 153
    • 0019797417 scopus 로고
    • Psychoneuroendocrine influences on immunocompetence and neoplasia
    • Riley V 1981 Psychoneuroendocrine influences on immunocompetence and neoplasia. Science 212:110-1109
    • (1981) Science , vol.212 , pp. 110-1109
    • Riley, V.1
  • 154
    • 0026540852 scopus 로고
    • Effects of stress on the growth of a fibrosarcoma in nu/nu and conventional mice
    • Aarstad HJ, Seljelid R 1992 Effects of stress on the growth of a fibrosarcoma in nu/nu and conventional mice. Scand J Immunol 35:209-215
    • (1992) Scand J Immunol , vol.35 , pp. 209-215
    • Aarstad, H.J.1    Seljelid, R.2
  • 155
    • 0029134905 scopus 로고
    • Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation
    • Stewart T, Tsai S-CJ, Grayson H, Henderson R, Opelz G 1995 Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. Lancet 346:796-798
    • (1995) Lancet , vol.346 , pp. 796-798
    • Stewart, T.1    Tsai, S.-C.J.2    Grayson, H.3    Henderson, R.4    Opelz, G.5
  • 156
    • 0025785443 scopus 로고
    • Aromatase activity in human adipose tissue stromal cells; the effect of fetal bovine serum fractions on dexamethasone-stimulated aromatization
    • Leuprasitsakul P, Longcope C 1991 Aromatase activity in human adipose tissue stromal cells; the effect of fetal bovine serum fractions on dexamethasone-stimulated aromatization. J Steroid Biochem Mol Biol 39:353-357
    • (1991) J Steroid Biochem Mol Biol , vol.39 , pp. 353-357
    • Leuprasitsakul, P.1    Longcope, C.2
  • 157
    • 0025343696 scopus 로고
    • Glucocorticoid upregulation of high affinity interleukin-6 receptors on human epithelial cells
    • Snyers L, De Wit L, Content J 1990 Glucocorticoid upregulation of high affinity interleukin-6 receptors on human epithelial cells. Proc Natl Acad Sci USA 87:2838-2842
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2838-2842
    • Snyers, L.1    De Wit, L.2    Content, J.3
  • 158
    • 0025047444 scopus 로고
    • On the mechanism of efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer TATA box and RNA start site (Inr Motif) occlusion
    • Ray A, La Forge KS, Sehgal PB 1990 On the mechanism of efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer TATA box and RNA start site (Inr Motif) occlusion. Mol Cell Biol 10:5736-5746
    • (1990) Mol Cell Biol , vol.10 , pp. 5736-5746
    • Ray, A.1    La Forge, K.S.2    Sehgal, P.B.3
  • 159
    • 0029563186 scopus 로고
    • The role and proposed mechanism by which oestradiol 17β-hydroxysteroid dehydrogenase regulates breast tumour oestrogen concentrations
    • Duncan LJ, Reed MJ 1995 The role and proposed mechanism by which oestradiol 17β-hydroxysteroid dehydrogenase regulates breast tumour oestrogen concentrations. J Steroid Biochem Mol Biol 55:565-572
    • (1995) J Steroid Biochem Mol Biol , vol.55 , pp. 565-572
    • Duncan, L.J.1    Reed, M.J.2
  • 160
    • 0015183737 scopus 로고
    • An immunostimulation theory of tumor development
    • Prehn RT, Lappé MA 1971 An immunostimulation theory of tumor development. Transplant Rev 7:26-54
    • (1971) Transplant Rev , vol.7 , pp. 26-54
    • Prehn, R.T.1    Lappé, M.A.2
  • 162
    • 0025219109 scopus 로고
    • Constitutive production of human interleukin for DA cells/leukemia inhibitory factor by human cell lines derived from various tissues
    • Gasean H, Anegon I, Praloran V, Naulet J, Godard A, Soulillon J-P, Jacques Y 1990 Constitutive production of human interleukin for DA cells/leukemia inhibitory factor by human cell lines derived from various tissues. J Immunol 144:2592-2598
    • (1990) J Immunol , vol.144 , pp. 2592-2598
    • Gasean, H.1    Anegon, I.2    Praloran, V.3    Naulet, J.4    Godard, A.5    Soulillon, J.-P.6    Jacques, Y.7
  • 163
    • 0028958818 scopus 로고
    • Interleukin-3: A putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts
    • Speirs V, Birch MA, Boyle-Walsh E, Green AR, Gallagher JA, White MC 1995 Interleukin-3: a putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts. Int J Cancer 61:416-419
    • (1995) Int J Cancer , vol.61 , pp. 416-419
    • Speirs, V.1    Birch, M.A.2    Boyle-Walsh, E.3    Green, A.R.4    Gallagher, J.A.5    White, M.C.6
  • 164
    • 0029923911 scopus 로고    scopus 로고
    • Estrogen synthesis inhibitors for breast cancer: An introductory overview
    • Santen RJ 1996 Estrogen synthesis inhibitors for breast cancer: an introductory overview. Endocr Relat Cancer 3:1-8
    • (1996) Endocr Relat Cancer , vol.3 , pp. 1-8
    • Santen, R.J.1
  • 165
    • 0030021907 scopus 로고    scopus 로고
    • Aromatase inhibitors - Where are we now?
    • Miller WR 1996 Aromatase inhibitors - where are we now? Br J Cancer 73:415-417
    • (1996) Br J Cancer , vol.73 , pp. 415-417
    • Miller, W.R.1
  • 166
    • 0029593494 scopus 로고
    • Characteristics of human Types 1, 2 and 3 17β-hydroxysteroid dehydrogenase activities: Oxidation/reduction and inhibition
    • Luu-The V, Zhang Y, Poirier D, Labrie F 1995 Characteristics of human Types 1, 2 and 3 17β-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition. J Steroid Biochem Mol Biol 55:581-587
    • (1995) J Steroid Biochem Mol Biol , vol.55 , pp. 581-587
    • Luu-The, V.1    Zhang, Y.2    Poirier, D.3    Labrie, F.4
  • 167
    • 0029886370 scopus 로고    scopus 로고
    • Active sitedirected inhibition of estrone sulfatase by non steroidal Coumarin sulfamates
    • Woo LWL, Purohit A, Reed MJ, Potter BVL 1996 Active sitedirected inhibition of estrone sulfatase by non steroidal Coumarin sulfamates. J Med Chem 39:1349-1351
    • (1996) J Med Chem , vol.39 , pp. 1349-1351
    • Woo, L.W.L.1    Purohit, A.2    Reed, M.J.3    Potter, B.V.L.4
  • 168
    • 0029886489 scopus 로고    scopus 로고
    • New aromatase inhibitors: More selectivity, less toxicity, unfortunately, the same activity
    • Castiglione-Gertsch M 1996 New aromatase inhibitors: more selectivity, less toxicity, unfortunately, the same activity. Eur J Cancer 32A:393-395
    • (1996) Eur J Cancer , vol.32 A , pp. 393-395
    • Castiglione-Gertsch, M.1
  • 169
    • 9244245282 scopus 로고    scopus 로고
    • A randomised trial comparing two doses of the new selective aromatase inhibitor Anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer
    • Jonat W, Howell A, Blomqvist C, Eiermann W, Winblad G, Tyrrell C, Mauriac L, Roche H, Lundgren S, Hellmund R, Azab M 1996 A randomised trial comparing two doses of the new selective aromatase inhibitor Anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer Eur J Cancer 32A:404-412
    • (1996) Eur J Cancer , vol.32 A , pp. 404-412
    • Jonat, W.1    Howell, A.2    Blomqvist, C.3    Eiermann, W.4    Winblad, G.5    Tyrrell, C.6    Mauriac, L.7    Roche, H.8    Lundgren, S.9    Hellmund, R.10    Azab, M.11
  • 170
    • 0028986977 scopus 로고
    • Cytokine-binding proteins: Stimulating antagonists
    • Klein B, Brailly H 1995 Cytokine-binding proteins: stimulating antagonists. Immunol Today 16:216-220
    • (1995) Immunol Today , vol.16 , pp. 216-220
    • Klein, B.1    Brailly, H.2
  • 171
    • 0027013591 scopus 로고
    • Androstendiol regulates systemic resistance against lethal infections in mice
    • Loria RM, Padgett DA 1992 Androstendiol regulates systemic resistance against lethal infections in mice. Arch Virol 127:103-115
    • (1992) Arch Virol , vol.127 , pp. 103-115
    • Loria, R.M.1    Padgett, D.A.2
  • 172
    • 0028141375 scopus 로고
    • In vitro potentiation of lymphocyte activation by dehydroepiandrosterone, androstenediol and androstenetriol
    • Padgett DA, Loria RM 1994 In vitro potentiation of lymphocyte activation by dehydroepiandrosterone, androstenediol and androstenetriol. J Immunol 153:1544-1552
    • (1994) J Immunol , vol.153 , pp. 1544-1552
    • Padgett, D.A.1    Loria, R.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.