Modification of Escherichia coli thymidylate synthase at tyrosine-94 by 5-imidazolylpropynyl-2′-deoxyuridine 5′-monophosphate

Biochemistry

Volumn 42, Issue 15, 2003, Pages 4544-4551

  Saxl, Ruth L ^a   Reston, James ^a   Nie, Zhe ^b   Kalman, Thomas I ^b   Maley, Frank ^a  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; ENZYMES; ESCHERICHIA COLI; IONIZATION; MASS SPECTROMETRY;

ELECTROSPRAY IONIZATION;

BIOCHEMISTRY;

5 IMIDAZOYLPROPYNYL 2' DEOXYURIDINE 5' MONOPHOSPHATE; DEOXYURIDINE DERIVATIVE; DEOXYURIDINE PHOSPHATE; ESCHERICHIA COLI PROTEIN; FOLIC ACID; PEPTIDE; THYMIDYLATE SYNTHASE; TRYPSIN; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHEMICAL PARAMETERS; COMPETITIVE INHIBITION; COMPLEX FORMATION; CONCENTRATION RESPONSE; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; INHIBITION KINETICS; MASS SPECTROMETRY; MOLECULAR WEIGHT; MUTANT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYURACIL NUCLEOTIDES; ESCHERICHIA COLI; KINETICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THYMIDYLATE SYNTHASE; TYROSINE;

ESCHERICHIA COLI;

EID: 0037461291     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0268089     Document Type: Article

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