-
1
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
Putnam, D., and Kopeček, J. (1995) Polymer conjugates with anticancer activity. Adv. Polym. Sci. 122, 55-123.
-
(1995)
Adv. Polym. Sci.
, vol.122
, pp. 55-123
-
-
Putnam, D.1
Kopeček, J.2
-
2
-
-
0026926609
-
Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
-
Maeda, H., Seymour, L. W., and Miyamoto, Y. (1992) Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo. Bioconjugate Chem. 3, 351-362.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 351-362
-
-
Maeda, H.1
Seymour, L.W.2
Miyamoto, Y.3
-
3
-
-
0032959549
-
Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: First member of a new class of chemotherapeutic agents - Drug-polymer conjugates
-
Vasey, P. A., Kaye, S. B., Morrison, R., Twelves, C., Wilson, P., Duncan, R., Thomson, A. H., Murray, L. S., Hilditch, T. E., Murray, T., Burtles, S., Fraier, D., Frigerio, E., and Cassidy, J. (1999) Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: First member of a new class of chemotherapeutic agents - drug-polymer conjugates. Clin. Cancer Res. 5, 83-94.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 83-94
-
-
Vasey, P.A.1
Kaye, S.B.2
Morrison, R.3
Twelves, C.4
Wilson, P.5
Duncan, R.6
Thomson, A.H.7
Murray, L.S.8
Hilditch, T.E.9
Murray, T.10
Burtles, S.11
Fraier, D.12
Frigerio, E.13
Cassidy, J.14
-
4
-
-
0345367901
-
HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line
-
Minko, T., Kopečková, P., Pozharov, V., and Kopeček, J. (1998) HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line. J. Controlled Release 54, 223-233.
-
(1998)
J. Controlled Release
, vol.54
, pp. 223-233
-
-
Minko, T.1
Kopečková, P.2
Pozharov, V.3
Kopeček, J.4
-
5
-
-
0032766043
-
Comparison of the anticancer effect of free and HPMA copolymerbound adriamycin in human ovarian carcinoma cells
-
Minko, T., Kopečková, P., and Kopeček, J. (1999) Comparison of the anticancer effect of free and HPMA copolymerbound adriamycin in human ovarian carcinoma cells. Pharm. Res. 16, 986-996.
-
(1999)
Pharm. Res.
, vol.16
, pp. 986-996
-
-
Minko, T.1
Kopečková, P.2
Kopeček, J.3
-
6
-
-
0034049291
-
Efficacy of the chemotherapeutic action of HPMA copolymer-bound adriamycin in a solid tumor model of ovarian carcinoma
-
Minko, T., Kopečková, P., and Kopeček, J. (2000) Efficacy of the chemotherapeutic action of HPMA copolymer-bound adriamycin in a solid tumor model of ovarian carcinoma, Int. J. Cancer 86, 108-117.
-
(2000)
Int. J. Cancer
, vol.86
, pp. 108-117
-
-
Minko, T.1
Kopečková, P.2
Kopeček, J.3
-
7
-
-
0022635574
-
Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats
-
Duncan, R., Seymour, L. C. W., Scarlett, L., Lloyd, J. B., Rejmanová, P., and Kopeček, J. (1986) Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats. Biochim. Biophys. Acta 880, 62-71.
-
(1986)
Biochim. Biophys. Acta
, vol.880
, pp. 62-71
-
-
Duncan, R.1
Seymour, L.C.W.2
Scarlett, L.3
Lloyd, J.B.4
Rejmanová, P.5
Kopeček, J.6
-
8
-
-
0023930539
-
Antibody-directed affinity therapy applied to the immune system: In vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody
-
Říhová, B., Kopečková, P., Strohalm, J., Rossmann, P., Větvička, V., and Kopeček, J. (1988) Antibody-directed affinity therapy applied to the immune system: in vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody. Clin. Immunol. Immunopathol. 46, 100-114.
-
(1988)
Clin. Immunol. Immunopathol.
, vol.46
, pp. 100-114
-
-
Říhová, B.1
Kopečková, P.2
Strohalm, J.3
Rossmann, P.4
Větvička, V.5
Kopeček, J.6
-
9
-
-
0030042022
-
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 1. Influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro
-
Omelyanenko, V., Kopečková, P., Gentry, C., Shiah, J.-G., and Kopeček, J. (1996) HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 1. Influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro. J. Drug Targeting 3, 357-373.
-
(1996)
J. Drug Targeting
, vol.3
, pp. 357-373
-
-
Omelyanenko, V.1
Kopečková, P.2
Gentry, C.3
Shiah, J.-G.4
Kopeček, J.5
-
10
-
-
0032476812
-
Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors
-
Mammen, M., Choi, S.-K., and Whitesides, G. M. (1998) Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew. Chem., Int. Ed. 37, 2754-2794.
-
(1998)
Angew. Chem., Int. Ed.
, vol.37
, pp. 2754-2794
-
-
Mammen, M.1
Choi, S.-K.2
Whitesides, G.M.3
-
11
-
-
0029994114
-
Polyacrylamides bearing pendent α-sialoside groups strongly inhibit agglutination of erythrocytes by influenza virus: The strong inhibition reflects enhanced binding through cooperative polyvalent interactions
-
Sigal, G. B., Mammen, M., Dahmann, G., and Whitesides, G. M. (1996) Polyacrylamides bearing pendent α-sialoside groups strongly inhibit agglutination of erythrocytes by influenza virus: The strong inhibition reflects enhanced binding through cooperative polyvalent interactions. J. Am. Chem. Soc. 118, 3789-3800.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 3789-3800
-
-
Sigal, G.B.1
Mammen, M.2
Dahmann, G.3
Whitesides, G.M.4
-
12
-
-
0001652780
-
Biorecognition of sugar containing N-(2-hydroxypropyl)-methacrylamide copolymers by immobilized lectin
-
Rathi, R. C., Kopečková, P., and Kopeček, J. (1997) Biorecognition of sugar containing N-(2-hydroxypropyl)-methacrylamide copolymers by immobilized lectin. Macromol. Chem. Phys. 198, 1165-1180.
-
(1997)
Macromol. Chem. Phys.
, vol.198
, pp. 1165-1180
-
-
Rathi, R.C.1
Kopečková, P.2
Kopeček, J.3
-
13
-
-
0031049701
-
"Peptabody": A new type of high avidity binding protein
-
Terskikh, A. V., Le Doussal, J.-M., Crameri, R., Fisch, I., Mach, J.-P., and Kajava, A. V. (1997) "Peptabody": A new type of high avidity binding protein. Proc. Natl. Acad. Sci. U.S.A. 94, 1663-1668.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 1663-1668
-
-
Terskikh, A.V.1
Le Doussal, J.-M.2
Crameri, R.3
Fisch, I.4
Mach, J.-P.5
Kajava, A.V.6
-
14
-
-
0024965987
-
Identification of an epitope in the major envelope protein of Epstein-Barr virus that mediates viral binding to the B lymphocyte EBV receptor (CR2)
-
Nemerow, G. R., Hough ten, R. A., Moore, M. D., and Cooper, N. R. (1989) Identification of an epitope in the major envelope protein of Epstein-Barr virus that mediates viral binding to the B lymphocyte EBV receptor (CR2). Cell 56, 369-377.
-
(1989)
Cell
, vol.56
, pp. 369-377
-
-
Nemerow, G.R.1
Hough Ten, R.A.2
Moore, M.D.3
Cooper, N.R.4
-
15
-
-
0023848358
-
Characterization of a T-lymphocyte Epstein-Barr virus/ C3d receptor (CD21)
-
Fingeroth, J. D., Clabby, M. L., and Strominger, J. D. (1988) Characterization of a T-lymphocyte Epstein-Barr virus/ C3d receptor (CD21). J. Virol. 62, 1442-1447.
-
(1988)
J. Virol.
, vol.62
, pp. 1442-1447
-
-
Fingeroth, J.D.1
Clabby, M.L.2
Strominger, J.D.3
-
16
-
-
0027988292
-
Characterization of a 70-kDa, EBV gp350/220-binding protein on HSB-2 T cells
-
Hedrick, J. A., Lao, Z., Lipps, S. G., Wang, Y., Todd, S. C., Lambris, J. D., and Tsoukas, C. D. (1994) Characterization of a 70-kDa, EBV gp350/220-binding protein on HSB-2 T cells. J. Immunol. 153, 4418-4426.
-
(1994)
J. Immunol.
, vol.153
, pp. 4418-4426
-
-
Hedrick, J.A.1
Lao, Z.2
Lipps, S.G.3
Wang, Y.4
Todd, S.C.5
Lambris, J.D.6
Tsoukas, C.D.7
-
17
-
-
0023943233
-
Complement C3d,g/Epstein-Barr virus receptor density on human B-lymphocytes estimated by immunoenzymatic assay and immunocytochemistry
-
Rask, R., Rasmussen, J. M., Hansen, H. V., Bysted, P., and Svehag, S.-E. (1988) Complement C3d,g/Epstein-Barr virus receptor density on human B-lymphocytes estimated by immunoenzymatic assay and immunocytochemistry. J. Clin. Lab. Immunol. 25, 153-156.
-
(1988)
J. Clin. Lab. Immunol.
, vol.25
, pp. 153-156
-
-
Rask, R.1
Rasmussen, J.M.2
Hansen, H.V.3
Bysted, P.4
Svehag, S.-E.5
-
19
-
-
0032772050
-
Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes
-
Omelyanenko, V., Kopečková, P., Prakash, R. K., Ebert, C. D., and Kopeček, J. (1999) Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes. Pharm. Res. 16, 1010-1019.
-
(1999)
Pharm. Res.
, vol.16
, pp. 1010-1019
-
-
Omelyanenko, V.1
Kopečková, P.2
Prakash, R.K.3
Ebert, C.D.4
Kopeček, J.5
-
20
-
-
0342566718
-
-
unpublished data
-
Weis, J. H., et al. (unpublished data).
-
-
-
Weis, J.H.1
-
21
-
-
0030829523
-
Targeting of macromolecular prodrugs to T-lymphocytes
-
Prakash, R. K., Clemens, C. M., Ebert, C. D., Omelyanenko, V., Kopečková, P., and Kopeček, J. (1997) Targeting of macromolecular prodrugs to T-lymphocytes. Proc. Intl. Symp. Controlled Release Bioact. Mater. 24, 859-860.
-
(1997)
Proc. Intl. Symp. Controlled Release Bioact. Mater.
, vol.24
, pp. 859-860
-
-
Prakash, R.K.1
Clemens, C.M.2
Ebert, C.D.3
Omelyanenko, V.4
Kopečková, P.5
Kopeček, J.6
-
22
-
-
0030271515
-
Coiled coils: New structures and new functions
-
Lupas, A. (1996) Coiled coils: new structures and new functions. Trends Biochem. Sci. 21, 375-382.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 375-382
-
-
Lupas, A.1
-
23
-
-
0028949091
-
Tetravalent miniantibodies with high avidity assembling in Escherichia coli
-
Pack, P., Müller, K., Zahn, R., and Plückthun, A. (1995) Tetravalent miniantibodies with high avidity assembling in Escherichia coli. J. Mol. Biol. 246, 28-34.
-
(1995)
J. Mol. Biol.
, vol.246
, pp. 28-34
-
-
Pack, P.1
Müller, K.2
Zahn, R.3
Plückthun, A.4
-
24
-
-
0028231730
-
Design and characterization of an intramolecular antiparallel coiled coil peptide
-
Myszka, D. G., and Chaiken, I. M. (1994) Design and characterization of an intramolecular antiparallel coiled coil peptide. Biochemistry 33, 2363-2372.
-
(1994)
Biochemistry
, vol.33
, pp. 2363-2372
-
-
Myszka, D.G.1
Chaiken, I.M.2
-
25
-
-
0029977511
-
The coiled coil stem loop miniprotein as a presentation scaffold
-
Miceli, R., Myszka, D., Mao, J., Sathe, G., and Chaiken, I. (1996) The coiled coil stem loop miniprotein as a presentation scaffold. Drug Des. Discovery 13, 95-105.
-
(1996)
Drug Des. Discovery
, vol.13
, pp. 95-105
-
-
Miceli, R.1
Myszka, D.2
Mao, J.3
Sathe, G.4
Chaiken, I.5
-
26
-
-
0006429784
-
Phage expression of a de novo designed coiled coil stem loop miniprotein scaffold for constrained peptide library display
-
I. M. Chaiken and K. D. Janda, Eds. American Chemical Society, Washington, DC
-
Miceli, R. M., Myszka, D. G., Peishoff, C. E., and Chaiken, I. M. (1996) Phage expression of a de novo designed coiled coil stem loop miniprotein scaffold for constrained peptide library display. In Molecular Diversity and Combinatorial Chemistry: Libraries and Drug Discovery (I. M. Chaiken and K. D. Janda, Eds.) pp 172-185, American Chemical Society, Washington, DC.
-
(1996)
Molecular Diversity and Combinatorial Chemistry: Libraries and Drug Discovery
, pp. 172-185
-
-
Miceli, R.M.1
Myszka, D.G.2
Peishoff, C.E.3
Chaiken, I.M.4
-
27
-
-
0030052598
-
An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants
-
Waterman, M. J. F., Waterman, J. L. F., and Halazonetis, T. D. (1996) An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants. Cancer Res. 56, 158-163.
-
(1996)
Cancer Res.
, vol.56
, pp. 158-163
-
-
Waterman, M.J.F.1
Waterman, J.L.F.2
Halazonetis, T.D.3
-
28
-
-
0029850976
-
Engineering of a de novo-designed coiled-coil heterodimerization domain for the rapid detection, purification and characterization of recombinantly expressed peptides and proteins
-
Tripet, B., Yu, L., Bautista, D. L., Wong, W. Y., Irvin, R. T., and Hodges, R. S. (1996) Engineering of a de novo-designed coiled-coil heterodimerization domain for the rapid detection, purification and characterization of recombinantly expressed peptides and proteins. Protein Eng. 9, 1029-1042.
-
(1996)
Protein Eng.
, vol.9
, pp. 1029-1042
-
-
Tripet, B.1
Yu, L.2
Bautista, D.L.3
Wong, W.Y.4
Irvin, R.T.5
Hodges, R.S.6
-
29
-
-
0029974730
-
An engineered allosteric switch in leucin-zipper oligomerization
-
Gonzalez, L., Jr., Plecs, J. J., and Alber, T. (1996) An engineered allosteric switch in leucin-zipper oligomerization. Nat. Struct. Biol. 3, 510-515.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 510-515
-
-
Gonzalez L., Jr.1
Plecs, J.J.2
Alber, T.3
-
30
-
-
0029761897
-
A self-replicating peptide
-
Lee, D. H., Granja, J. R., Martinez, J. A., Severin, K., and Ghadiri, M. R. (1996) A self-replicating peptide. Nature 382, 525-528.
-
(1996)
Nature
, vol.382
, pp. 525-528
-
-
Lee, D.H.1
Granja, J.R.2
Martinez, J.A.3
Severin, K.4
Ghadiri, M.R.5
-
31
-
-
49549170184
-
Poly[N-(2-hydroxypropyl)methacrylamide] - I. Radical polymerization and copolymerization
-
Kopeček J., and Bažilová, H. (1973) Poly[N-(2-hydroxypropyl)methacrylamide] - I. Radical polymerization and copolymerization. Eur. Polym. J. 9, 7-14.
-
(1973)
Eur. Polym. J.
, vol.9
, pp. 7-14
-
-
Kopeček, J.1
Bažilová, H.2
-
32
-
-
0028150044
-
Synthesis and characterization of chelator-lipids for reversible immobilization of engineered proteins at self-assembled lipid interfaces
-
Schmitt, L., Dietrich, C., and Tampé, R. (1994) Synthesis and characterization of chelator-lipids for reversible immobilization of engineered proteins at self-assembled lipid interfaces. J. Am. Chem. Soc. 116, 8485-8491.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 8485-8491
-
-
Schmitt, L.1
Dietrich, C.2
Tampé, R.3
-
33
-
-
0001288057
-
Polymers containing enzymatically degradable bonds, 1. Chymotrypsin catalyzed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side-chains of copolymers of N-(2-hydroxypropyl)methacrylamide
-
Kopeček, J., Rejmanová, P., and Chytrý, V. (1981) Polymers containing enzymatically degradable bonds, 1. Chymotrypsin catalyzed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side-chains of copolymers of N-(2-hydroxypropyl)methacrylamide. Macromol. Chem. 182, 799-809.
-
(1981)
Macromol. Chem.
, vol.182
, pp. 799-809
-
-
Kopeček, J.1
Rejmanová, P.2
Chytrý, V.3
-
34
-
-
0033521939
-
Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains
-
Wang, C., Stewart, R. J., and Kopecek, J. (1999) Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains. Nature 397, 417-420.
-
(1999)
Nature
, vol.397
, pp. 417-420
-
-
Wang, C.1
Stewart, R.J.2
Kopecek, J.3
-
35
-
-
0003698308
-
-
John Wiley & Sons, Inc.
-
Briggs, D., Brown, A., and Vickerman, J. C. (1989) Handbook of Static Secondary Ion Mass Spectrometry, John Wiley & Sons, Inc.
-
(1989)
Handbook of Static Secondary Ion Mass Spectrometry
-
-
Briggs, D.1
Brown, A.2
Vickerman, J.C.3
-
36
-
-
0027917389
-
Static secondary ion mass spectrometry of adsorbed proteins
-
Mantus, D. S., Ratner, B. D., Carlson, B. A., and Moulder, J. F. (1993) Static secondary ion mass spectrometry of adsorbed proteins. Anal. Chem. 65, 1431-1438.
-
(1993)
Anal. Chem.
, vol.65
, pp. 1431-1438
-
-
Mantus, D.S.1
Ratner, B.D.2
Carlson, B.A.3
Moulder, J.F.4
-
37
-
-
0029102175
-
Phage display: Protein engineering by directed evolution
-
O'Neil, K. T., and Hoess, R. H. (1995) Phage display: protein engineering by directed evolution. Curr. Opin. Struct. Biol. 5, 443-449.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 443-449
-
-
O'Neil, K.T.1
Hoess, R.H.2
-
38
-
-
0029350176
-
Surface immobilization of biomolecules by light
-
Sigrist, H., Collioud, A., Clémence, J.-F., Gao, H., Luginbühl, R., Sänger, M., and Sundarabaru, G. (1995) Surface immobilization of biomolecules by light. Opt. Eng. 34, 2239-2348.
-
(1995)
Opt. Eng.
, vol.34
, pp. 2239-2348
-
-
Sigrist, H.1
Collioud, A.2
Clémence, J.-F.3
Gao, H.4
Luginbühl, R.5
Sänger, M.6
Sundarabaru, G.7
-
39
-
-
0026331267
-
X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil
-
O'Shea, E. K., Klemm, J. D., Kim, P. S., and Alber, T. (1991) X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science 254, 539-544.
-
(1991)
Science
, vol.254
, pp. 539-544
-
-
O'Shea, E.K.1
Klemm, J.D.2
Kim, P.S.3
Alber, T.4
-
40
-
-
0028559469
-
Effect of chain length on the formation and stability of synthetic a-helical coiled coils
-
Su, J. Y., Hodges, R. S., and Kay, C. M. (1994) Effect of chain length on the formation and stability of synthetic a-helical coiled coils. Biochemistry 33, 15501-15510.
-
(1994)
Biochemistry
, vol.33
, pp. 15501-15510
-
-
Su, J.Y.1
Hodges, R.S.2
Kay, C.M.3
-
41
-
-
0030077272
-
A self-assembled monolayer for the binding and study of histidine-tagged proteins by surface plasmon resonance
-
Sigal, G. B., Bamdad, C., Barberis, A., Strominger, J., and Whitesides, G. M. (1996) A self-assembled monolayer for the binding and study of histidine-tagged proteins by surface plasmon resonance. Anal. Chem. 68, 490-497.
-
(1996)
Anal. Chem.
, vol.68
, pp. 490-497
-
-
Sigal, G.B.1
Bamdad, C.2
Barberis, A.3
Strominger, J.4
Whitesides, G.M.5
|