-
1
-
-
0030960899
-
New targets for antimalarial drug discovery
-
Olliaro P., Wirth D. New targets for antimalarial drug discovery. J. Pharm. Pharmacol. 49:1997;29-33.
-
(1997)
J. Pharm. Pharmacol.
, vol.49
, pp. 29-33
-
-
Olliaro, P.1
Wirth, D.2
-
2
-
-
0030990206
-
The treatment of malaria with iron chelators
-
Hider R.C., Liu Z. The treatment of malaria with iron chelators. J. Pharm. Pharmacol. 49:1997;59-64.
-
(1997)
J. Pharm. Pharmacol.
, vol.49
, pp. 59-64
-
-
Hider, R.C.1
Liu, Z.2
-
4
-
-
0019948542
-
Plasmodium falciparum: Inhibition of in vitro growth by desferrioxamine
-
Raventos-Suarez C., Pollack S., Nagel R.L. Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine. Am. J. Trop. Med. Hyg. 31:1982;919-922.
-
(1982)
Am. J. Trop. Med. Hyg.
, vol.31
, pp. 919-922
-
-
Raventos-Suarez, C.1
Pollack, S.2
Nagel, R.L.3
-
5
-
-
0023740339
-
Desferoxamine inhibition of malaria is independent of host iron status
-
Hershko C., Peto T.E.A. Desferoxamine inhibition of malaria is independent of host iron status. J. Exp. Med. 168:1988;375-387.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 375-387
-
-
Hershko, C.1
Peto, T.E.A.2
-
6
-
-
0021984450
-
Suppression of mouse infections by desferrioxamine B
-
Fritsch G., Treumer J., Spira D.T., Jung A. Suppression of mouse infections by desferrioxamine B. Exp. Med. 60:1985;171-174.
-
(1985)
Exp. Med.
, vol.60
, pp. 171-174
-
-
Fritsch, G.1
Treumer, J.2
Spira, D.T.3
Jung, A.4
-
8
-
-
0026459549
-
Effect of iron chelation therapy on recovery from deep coma in children with cerebral malaria
-
Gordeuk V.R., Thuma P.E., Brittenham G.M., McLaren C., Parry D., Backentose A., Biemba G., Msiska R., Holmes L., McKinley E., Vargas L., Gilkeson R., Poltera A.A. Effect of iron chelation therapy on recovery from deep coma in children with cerebral malaria. New Engl. J. Med. 327:1992;1473-1477.
-
(1992)
New Engl. J. Med.
, vol.327
, pp. 1473-1477
-
-
Gordeuk, V.R.1
Thuma, P.E.2
Brittenham, G.M.3
McLaren, C.4
Parry, D.5
Backentose, A.6
Biemba, G.7
Msiska, R.8
Holmes, L.9
McKinley, E.10
Vargas, L.11
Gilkeson, R.12
Poltera, A.A.13
-
10
-
-
0028859989
-
Iron chelators as antimalarials: The biochemical basis of selective cytotoxicity
-
Cabantchik Z.I. Iron chelators as antimalarials: the biochemical basis of selective cytotoxicity. Parasitol. Today. 11:1995;74-78.
-
(1995)
Parasitol. Today
, vol.11
, pp. 74-78
-
-
Cabantchik, Z.I.1
-
11
-
-
0028272483
-
Mode of action of iron(III) chelators as antimalarials. II. Evidence for differential on parasite iron-dependent nucleic acid synthesis
-
Lytton S.D., Mester B., Libman J., Shanzer A., Cabantchik Z.I. Mode of action of iron(III) chelators as antimalarials. II. Evidence for differential on parasite iron-dependent nucleic acid synthesis. Blood. 84:1994;910-915.
-
(1994)
Blood
, vol.84
, pp. 910-915
-
-
Lytton, S.D.1
Mester, B.2
Libman, J.3
Shanzer, A.4
Cabantchik, Z.I.5
-
12
-
-
0027505576
-
Mode of action of iron(III) chelators as antimalarials. I. Membranes permeation properties and cytotoxic activity
-
Lytton S.D., Mester B., Dayan I., Glickstein H., Libman J., Shanzer A., Catbanchik Z.I. Mode of action of iron(III) chelators as antimalarials. I. Membranes permeation properties and cytotoxic activity. Blood. 81:1993;214-221.
-
(1993)
Blood
, vol.81
, pp. 214-221
-
-
Lytton, S.D.1
Mester, B.2
Dayan, I.3
Glickstein, H.4
Libman, J.5
Shanzer, A.6
Catbanchik, Z.I.7
-
13
-
-
0029816603
-
In vitro activities of novel catecholate siderophore against Plasmodium falciparum
-
Pradines B., Ramiandrasoa F., Basco L.K., Bricard L., Kunesch G., Le Bras J. In vitro activities of novel catecholate siderophore against Plasmodium falciparum. Antimicrob. Agents Chemother. 40:1996;2094-2098.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 2094-2098
-
-
Pradines, B.1
Ramiandrasoa, F.2
Basco, L.K.3
Bricard, L.4
Kunesch, G.5
Le Bras, J.6
-
14
-
-
0036668105
-
Iron chelators as antimalarial agents: In vitro activity of dicatecholate against Plasmodium falciparum
-
Pradines B., Rolain J.M., Ramiandrasoa F., Fusai T., Mosnier J., Rogier C., Daries W., Baret E., Kunesch G., Le Bras J., Parzy D. Iron chelators as antimalarial agents: in vitro activity of dicatecholate against Plasmodium falciparum. J. Antimicrob. Chemother. 50:2002;177-187.
-
(2002)
J. Antimicrob. Chemother.
, vol.50
, pp. 177-187
-
-
Pradines, B.1
Rolain, J.M.2
Ramiandrasoa, F.3
Fusai, T.4
Mosnier, J.5
Rogier, C.6
Daries, W.7
Baret, E.8
Kunesch, G.9
Le Bras, J.10
Parzy, D.11
-
15
-
-
0036136817
-
In vitro potentiation of antibiotic activities by a catecholate iron chelator against chloroquine-resistant Plasmodium falciparum
-
Pradines B., Ramiandrasoa F., Rolain J.M., Rogier C., Mosnier J., Daries W., Fusai T., Kunesch G., Le Bras J., Parzy D. In vitro potentiation of antibiotic activities by a catecholate iron chelator against chloroquine-resistant Plasmodium falciparum. Antimicrob. Agents Chemother. 46:2002;225-228.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 225-228
-
-
Pradines, B.1
Ramiandrasoa, F.2
Rolain, J.M.3
Rogier, C.4
Mosnier, J.5
Daries, W.6
Fusai, T.7
Kunesch, G.8
Le Bras, J.9
Parzy, D.10
-
16
-
-
0032770944
-
Deferoxamine: Stimulation of hematin polymerisation and antagonism of its inhibition by chloroquine
-
Vippagunta S.R., Dorn A., Bubendorf A., Ridley R.G., Vennerstrom J.L. Deferoxamine: stimulation of hematin polymerisation and antagonism of its inhibition by chloroquine. Biochem. Pharmacol. 58:1999;817-824.
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 817-824
-
-
Vippagunta, S.R.1
Dorn, A.2
Bubendorf, A.3
Ridley, R.G.4
Vennerstrom, J.L.5
-
17
-
-
0036174441
-
Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae
-
Emerson L.R., Nau M.E., Martin R.K., Kyle D.E., Vahey M., Wirth D.F. Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 46:2002;786-787.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 786-787
-
-
Emerson, L.R.1
Nau, M.E.2
Martin, R.K.3
Kyle, D.E.4
Vahey, M.5
Wirth, D.F.6
-
18
-
-
0016645128
-
Dispositif automatique de transfert de gaz (tritium, deutérium, hydrogène)
-
Morgat J.L., Demares J., Cornu M. Dispositif automatique de transfert de gaz (tritium, deutérium, hydrogène). J. Labelled Compd. 11:1975;257-264.
-
(1975)
J. Labelled Compd.
, vol.11
, pp. 257-264
-
-
Morgat, J.L.1
Demares, J.2
Cornu, M.3
-
19
-
-
0018704491
-
Synchronization of Plasmodium falciparum erythrocytic stages in culture
-
Lambros C., Vanderberg J.P. Synchronization of Plasmodium falciparum erythrocytic stages in culture. J. Parasitol. 65:1979;418-420.
-
(1979)
J. Parasitol.
, vol.65
, pp. 418-420
-
-
Lambros, C.1
Vanderberg, J.P.2
-
20
-
-
0344867895
-
Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum
-
Bray P.G., Janneh O., Raynes K.J., Munghthin M., Ginsburgh H., Ward S.A. Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum. J. Cell Biol. 145:1999;363-376.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 363-376
-
-
Bray, P.G.1
Janneh, O.2
Raynes, K.J.3
Munghthin, M.4
Ginsburgh, H.5
Ward, S.A.6
-
21
-
-
0035984775
-
In vitro increase in chloroquine accumulation induced by dihydroethano-and ethenoanthracene derivatives in Plasmodium falciparum parasitized erythrocytes
-
Pradines B., Alibert S., Houdoin C., Santelli-Rouvier C., Mosnier J., Fusai T., Rogier C., Barbe J., Parzy D. In vitro increase in chloroquine accumulation induced by dihydroethano-and ethenoanthracene derivatives in Plasmodium falciparum parasitized erythrocytes. Antimicrob. Agents Chemother. 46:2002;2061-2068.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 2061-2068
-
-
Pradines, B.1
Alibert, S.2
Houdoin, C.3
Santelli-Rouvier, C.4
Mosnier, J.5
Fusai, T.6
Rogier, C.7
Barbe, J.8
Parzy, D.9
-
22
-
-
0027953538
-
Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum
-
Bray P.G., Boulter M.K., Ritchie G.Y., Howells R.E., Ward S.A. Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum. Mol. Biochem. Parasitol. 63:1994;87-94.
-
(1994)
Mol. Biochem. Parasitol.
, vol.63
, pp. 87-94
-
-
Bray, P.G.1
Boulter, M.K.2
Ritchie, G.Y.3
Howells, R.E.4
Ward, S.A.5
-
23
-
-
0028045978
-
Reversal of chloroquine resistance in falciparummalaria by some calcium channel inhibitors and optical isomers is independent of calcium channel blockade
-
Ye Z., van Dycke K. Reversal of chloroquine resistance in falciparummalaria by some calcium channel inhibitors and optical isomers is independent of calcium channel blockade. Drug Chem. Toxicol. 17:1994;149-162.
-
(1994)
Drug Chem. Toxicol.
, vol.17
, pp. 149-162
-
-
Ye, Z.1
Van Dycke, K.2
-
26
-
-
0035800037
-
Downregulation of protein kinase C inhibits activation of mitochondrial K (ATP) channels by diazoxide
-
Wang Y., Takashi E., Xu M., Ayub A., Ashraf M. Downregulation of protein kinase C inhibits activation of mitochondrial K (ATP) channels by diazoxide. Circulation. 104:2001;85-90.
-
(2001)
Circulation
, vol.104
, pp. 85-90
-
-
Wang, Y.1
Takashi, E.2
Xu, M.3
Ayub, A.4
Ashraf, M.5
-
27
-
-
0035876663
-
Theoretical analysis of the molecular determinants responsible for the K(+) channel blocking by aminopyridines
-
Nino A., Munoz-Caro C. Theoretical analysis of the molecular determinants responsible for the K(+) channel blocking by aminopyridines. Biophys. Chem. 91:2001;49-60.
-
(2001)
Biophys. Chem.
, vol.91
, pp. 49-60
-
-
Nino, A.1
Munoz-Caro, C.2
-
28
-
-
0027158425
-
Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons
-
Yoon K.W., Covey D.F., Rothman S.M. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons. J. Physiol. 464:1993;423-439.
-
(1993)
J. Physiol.
, vol.464
, pp. 423-439
-
-
Yoon, K.W.1
Covey, D.F.2
Rothman, S.M.3
-
29
-
-
0017843255
-
A method for testing for synergy with any number of agents
-
Berenbaum M.C. A method for testing for synergy with any number of agents. J. Infect. Dis. 137:1978;122-130.
-
(1978)
J. Infect. Dis.
, vol.137
, pp. 122-130
-
-
Berenbaum, M.C.1
-
30
-
-
0025866878
-
Direct access to serum macromolecules by intraerythrocytic malaria parasites
-
Pouvelle B., Spiegel R., Hsiao L., Howard R.J., Morris R.L., Thomas A.P., Tarashchi T.F. Direct access to serum macromolecules by intraerythrocytic malaria parasites. Nature. 353:1991;73-75.
-
(1991)
Nature
, vol.353
, pp. 73-75
-
-
Pouvelle, B.1
Spiegel, R.2
Hsiao, L.3
Howard, R.J.4
Morris, R.L.5
Thomas, A.P.6
Tarashchi, T.F.7
-
31
-
-
0027392073
-
The antimalarial action of Desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites
-
Loyevsky M., Lytton S.D., Mester B., Libman J., Shanzer A., Cabantchick Z.I. The antimalarial action of Desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites. J. Clin. Invest. 91:1993;218-222.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 218-222
-
-
Loyevsky, M.1
Lytton, S.D.2
Mester, B.3
Libman, J.4
Shanzer, A.5
Cabantchick, Z.I.6
-
32
-
-
0022930795
-
14C -Desferrioxamine B: Uptake into erythrocytes infected with Plasmodium falciparum
-
14C -Desferrioxamine B: uptake into erythrocytes infected with Plasmodium falciparum Z. Parasitikd. 72:1986;709-713.
-
(1986)
Z. Parasitikd.
, vol.72
, pp. 709-713
-
-
Fritsch, G.1
Jung, A.2
-
33
-
-
0007740769
-
Susceptibility of human malaria parasites to chloroquine is pH dependent
-
Yayon A., Cabantchik Z.I., Ginsburg H. Susceptibility of human malaria parasites to chloroquine is pH dependent. Proc. Natl. Acad. Sci. U.S.A. 82:1985;2784-2787.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 2784-2787
-
-
Yayon, A.1
Cabantchik, Z.I.2
Ginsburg, H.3
-
34
-
-
0022347074
-
Antimalarials increase vesicle pH in Plasmodium falciparum
-
Krogstad D.J., Schlesinger P.H., Gluzman I.Y. Antimalarials increase vesicle pH in Plasmodium falciparum. J. Cell Biol. 101:1985;2302-2309.
-
(1985)
J. Cell Biol.
, vol.101
, pp. 2302-2309
-
-
Krogstad, D.J.1
Schlesinger, P.H.2
Gluzman, I.Y.3
-
35
-
-
0000615539
-
Antimalarial schizonticides: Ferriprotoporphyrin IX interaction hypothesis
-
Fitch C.D. Antimalarial schizonticides: ferriprotoporphyrin IX interaction hypothesis. Parasitol. Today. 2:1986;330-331.
-
(1986)
Parasitol. Today
, vol.2
, pp. 330-331
-
-
Fitch, C.D.1
-
36
-
-
0032520664
-
An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials
-
Dorn A., Vippagunta S.R., Matile H., Jaquet C., Vennerstrom J.L., Ridley R.G. An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials. Biochem. Pharmacol. 55:1998;727-736.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 727-736
-
-
Dorn, A.1
Vippagunta, S.R.2
Matile, H.3
Jaquet, C.4
Vennerstrom, J.L.5
Ridley, R.G.6
-
37
-
-
0032520193
-
Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum
-
Adovelande J., Deleze J., Schrevel J. Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum. Biochem. Pharmacol. 55:1998;433-440.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 433-440
-
-
Adovelande, J.1
Deleze, J.2
Schrevel, J.3
-
38
-
-
0029087801
-
Verapamil reversal of chloroquine resistance in the malaria parasites Plasmodium falciparum is specific for resistant parasites and independent of weak base effect
-
Martiney J.A., Cerami A., Slater A.F.G. Verapamil reversal of chloroquine resistance in the malaria parasites Plasmodium falciparum is specific for resistant parasites and independent of weak base effect. J. Biol. Chem. 270:1995;22393-22398.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22393-22398
-
-
Martiney, J.A.1
Cerami, A.2
Slater, A.F.G.3
-
39
-
-
0026410189
-
Reversal of chloroquine resistance of wild isolates of Plasmodium falciparum by desipramine
-
Carosi G., Caligaris S., Fadat G., Castelli F., Matteelli A., Komka-Bemba D., Roscigno G. Reversal of chloroquine resistance of wild isolates of Plasmodium falciparum by desipramine. Trans. R. Soc. Trop. Med. Hyg. 85:1991;723-724.
-
(1991)
Trans. R. Soc. Trop. Med. Hyg.
, vol.85
, pp. 723-724
-
-
Carosi, G.1
Caligaris, S.2
Fadat, G.3
Castelli, F.4
Matteelli, A.5
Komka-Bemba, D.6
Roscigno, G.7
-
40
-
-
0036592529
-
In vitro reversal of chloroquine resistance in Plasmodium falciparum with dihydroethanoanthracene derivatives
-
Pradines B., Alibert-Franco S., Houdoin C., Mosnier J., Santelli-Rouvier C., Papa V., Rogier C., Fusai T., Barbe J., Parzy D. In vitro reversal of chloroquine resistance in Plasmodium falciparum with dihydroethanoanthracene derivatives. Am. J. Trop. Med. Hyg. 66:2002;661-666.
-
(2002)
Am. J. Trop. Med. Hyg.
, vol.66
, pp. 661-666
-
-
Pradines, B.1
Alibert-Franco, S.2
Houdoin, C.3
Mosnier, J.4
Santelli-Rouvier, C.5
Papa, V.6
Rogier, C.7
Fusai, T.8
Barbe, J.9
Parzy, D.10
-
41
-
-
0037130184
-
Synthesis and effects on chloroquine susceptibility in Plasmodium falciparum of a series of new dihydroanthracene derivatives
-
Alibert S., Santelli-Rouvier C., Pradines B., Houdoin C., Parzy D., Karolak-Wojciechowska J., Barbe J. Synthesis and effects on chloroquine susceptibility in Plasmodium falciparum of a series of new dihydroanthracene derivatives. J. Med. Chem. 45:2002;3195-3209.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3195-3209
-
-
Alibert, S.1
Santelli-Rouvier, C.2
Pradines, B.3
Houdoin, C.4
Parzy, D.5
Karolak-Wojciechowska, J.6
Barbe, J.7
-
42
-
-
0027503026
-
Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys
-
Kyle D.E., Milhous W.K., Rossan R.N. Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys. Am. J. Trop. Med. Hyg. 48:1993;126-133.
-
(1993)
Am. J. Trop. Med. Hyg.
, vol.48
, pp. 126-133
-
-
Kyle, D.E.1
Milhous, W.K.2
Rossan, R.N.3
-
43
-
-
0032772698
-
Effect of chlorpheniramine on the pharmacokinetics of response to chloroquine of Nigerian children with falciparum malaria
-
Okonkwo C.A., Coker H.A.B., Agomo P.U., Ogunbanwo J.A., Mafe A.G., Agomo C.O., Afolabi B.M. Effect of chlorpheniramine on the pharmacokinetics of response to chloroquine of Nigerian children with falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 93:1999;306-311.
-
(1999)
Trans. R. Soc. Trop. Med. Hyg.
, vol.93
, pp. 306-311
-
-
Okonkwo, C.A.1
Coker, H.A.B.2
Agomo, P.U.3
Ogunbanwo, J.A.4
Mafe, A.G.5
Agomo, C.O.6
Afolabi, B.M.7
-
44
-
-
0031037514
-
Identification of a chloroquine importer in Plasmodium falciparum: Differences in import kinetics are genetically linked with the chloroquine resistant phenotype
-
Sanchez C.P., Wünsch S., Lanzer M. Identification of a chloroquine importer in Plasmodium falciparum: differences in import kinetics are genetically linked with the chloroquine resistant phenotype. J. Biol. Chem. 272:1997;2652-2658.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2652-2658
-
-
Sanchez, C.P.1
Wünsch, S.2
Lanzer, M.3
-
45
-
-
0033827908
-
Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine
-
Dzekunov S.M., Ursos L.M.B., Roepe P.D. Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine. Mol. Biochem. Parasitol. 110:2000;107-124.
-
(2000)
Mol. Biochem. Parasitol.
, vol.110
, pp. 107-124
-
-
Dzekunov, S.M.1
Ursos, L.M.B.2
Roepe, P.D.3
-
46
-
-
0033824184
-
The effects of chloroquine and verapamil on digestive vacuolar pH of P. falciparum either sensitive or resistant to chloroquine
-
Ursos L.M.B., Dzekunov S.M., Roepe P.D. The effects of chloroquine and verapamil on digestive vacuolar pH of P. falciparum either sensitive or resistant to chloroquine. Mol. Biochem. Parasitol. 110:2000;125-134.
-
(2000)
Mol. Biochem. Parasitol.
, vol.110
, pp. 125-134
-
-
Ursos, L.M.B.1
Dzekunov, S.M.2
Roepe, P.D.3
-
47
-
-
0035862696
-
Antimalarial drugs influence the pH dependent solubility of heme via apparent nucleation phenomena
-
Ursos L.M.B., Dubay K.F., Roepe P.D. Antimalarial drugs influence the pH dependent solubility of heme via apparent nucleation phenomena. Mol. Biochem. Parasitol. 112:2001;11-17.
-
(2001)
Mol. Biochem. Parasitol.
, vol.112
, pp. 11-17
-
-
Ursos, L.M.B.1
Dubay, K.F.2
Roepe, P.D.3
-
48
-
-
0025102616
-
Parasite uptake of desferrioxamine: A prerequisite for antimalarial activity
-
Scott M.D., Ranz A., Kuypers F.A., Lubin B.H., Meshnick S.R. Parasite uptake of desferrioxamine: a prerequisite for antimalarial activity. Br. J. Haematol. 75:1990;598-603.
-
(1990)
Br. J. Haematol.
, vol.75
, pp. 598-603
-
-
Scott, M.D.1
Ranz, A.2
Kuypers, F.A.3
Lubin, B.H.4
Meshnick, S.R.5
|