Deferoxamine: Stimulation of hematin polymerization and antagonism of its inhibition by chloroquine

Biochemical Pharmacology

Volumn 58, Issue 5, 1999, Pages 817-824

  Vippagunta, Sudha R ^a   Dorn, Arnulf ^b   Bubendorf, André ^b   Ridley, Robert G ^b   Vennerstrom, Jonathan L ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Pharma Research   (Switzerland)

Author keywords

Association constant; Chloroquine; Deferoxamine; Hematin oxo dimer; Hematin polymerization; Malaria

Indexed keywords

CHLOROQUINE; DEFEROXAMINE; HEMATIN;

ARTICLE; CALORIMETRY; DRUG ANTAGONISM; MALARIA; POLYMERIZATION; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; BIOPOLYMERS; CHELATING AGENTS; CHLOROQUINE; DEFEROXAMINE; DRUG INTERACTIONS; HEMIN; HYDROGEN-ION CONCENTRATION; PLASMODIUM FALCIPARUM; SOLUBILITY;

EID: 0032770944     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00161-6     Document Type: Article

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