Homocysteine and alcohol consumption: An ambiguous relationship and a new paradox;Homocystéine et consommation d'alcool: Une relation ambiguedie; et un nouveau paradoxe

Presse Medicale

Volumn 32, Issue 6, 2003, Pages 262-267

  Schlienger, Jean Louis ^a  

^a HÔPITAL DE HAUTEPIERRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE;

ALCOHOL CONSUMPTION; ALCOHOLISM; AMINO ACID BLOOD LEVEL; CARDIOVASCULAR RISK; COFFEE; CORRELATION ANALYSIS; ENVIRONMENTAL FACTOR; HEART PROTECTION; HEREDITY; HUMAN; NUTRITION; REVIEW;

ALCOHOL DRINKING; BEER; CARDIOVASCULAR DISEASES; EPIDEMIOLOGIC STUDIES; HOMOCYSTEINE; HUMANS; RISK FACTORS;

EID: 0037440795     PISSN: 07554982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (46)

1. McCully KS. Vascular pathology of homocysteinemia: implications for the pathologenesis of arteriosclerosis. Am J Pathol 1969; 56: 111-28
2. Wilcken DEL, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 1976; 57: 1079-82
3. Vollset SE, Refsum H, Tverdal A et al. Plasma total homocysteine and cardiovascular and non cardiovascular mortality: the Hordaland Homocysteine Study, Am J. Clin Nutr 2001; 74: 130-6.
4. Ueland PM, Refsum H, Beresford SAA, Vollset SE. The controversy over homocysteine and cardiovascular risk. Am J Clin Nutr 2000; 72: 324-32.
5. Graham IM, Daly LE, Refsum H. Plasma homocysteine as a risk factor for vascular disease. The European concerted action project. JAMA 1997; 277: 1775-81
6. Brattstrom L. Common mutation in the methylenetetrahydrofolate reductase gene offers no support for wild hyperhomocysteinemia being a causal risk factor for cardiovascular disease. Circulation 1997; 96: 3805-7
7. Brattstrom L, Wilcken DE, Ohrwik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leeds to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis Circulation 1998; 98: 2520-6
8. Engbersen AM, Franken DG, Boers GH, Stevens EM, Trijbels FJ, Blom HJ. Thermolabile 5, 10, methylenetetrahydrofolate reductase as a cause of wild hyperhomocysteinemia. Am J. Hum Genet 1995; 56: 142-50.
9. Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993; 270: 2693-8
10. Selhub J, Jacques PF, Rosenberg IH. Serum total homocysteine concentration in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamins status to high serum concentration. Ann Intern. Med 1999; 131: 331-9
11. Clarke R, Collins R. Care dietary supplements with folic acid or vitamine B6 reduce cardiovascular risk? Design of clinical trials to test the homocysteine hypothesis of vascular disease. J. Cardiovascular Risk 1998; 5: 249-55
12. Peterson JC, Spence JD. Vitamins and progression of atherosclerosis in hyperhomocysteinemia. Lancet 1998; 351: 263.
13. De Jong SC, Stehouwer CD, Van Den Berg M, Geurtz TW, Bouter LM, Rauwerda JA. Normohomocysteinemia and vitamine treated hyperhomocysteinemia are associated with similar risks of cardiovascular events in patients with primature peripheral arterial occlusive disease. A prospective cohort study. J. Intern. Med 1999; 246: 87-96.
14. Vermeulen EG, Stehouwer CD, Twisk JW. Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subdinal atherosclerosis: a randomised, placebo-controlled trial. Lancet 2000; 355: 517-22
15. Arnadottir M, Hultberg B, Nilsson-Ehle P, Thysell H. The effect of reduced glomerular filtration rate on plasma total homocysteine concentration. Scent. J. Clin. Lab Invest 1996; 56: 41-6.
16. Wollesen F, Brattstrom L, Refsum H, Ueland PM, Berglund L, Berne C. Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus. Kidney Int 1999; 55: 1028-55.
17. Brattstrom L, Wilcken DEL. Homocysteine and cardiovascular disease: cause or effect? Am J. Clin. Nutr 2000; 72: 315-23.
18. Selhub J, Jacques PF, Bostom AG, D'Agostinho RB, Wilson PWF, Belanger AJ. Relationship between plasma homocysteine, vitamin status and extracanial carotidartery stenosis in the Framingham Study. J Nutr 1996; 126: 1258s-65s.
19. Verhoef P, Stampfer MJ, Buring JE, Gaziano JM, Allen RH, Stabler JP. Homocysteine metabolism and risk of myocardial infarction: relationship with vitamins B6, B12 and folate. Am J Epidemiol 1996; 143: 845-59.
20. Subar AF, Block G, James LD. Folate intake and food sources in the US population. Am J Clin Nutr 1989; 50: 508-16.
21. Tucker KL, Mahnken B, Wilson PWF, Jacques P, Selhub J. Folic acid fortification of the food supply. Potential benefits and risks for the elderly population. JAMA 1996; 276: 1879-185
22. Lussier-Cacan J, Xhignesse M, Piolot A, Sehub J, Davignon J, Genest Jr J. Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits. Am J Clin Nutr 1996; 64: 687-93.
23. Nygard O, Refsum H, Ueland PM, Vollset SE. Major life determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study. Am J Clin Nutr 1998; 67: 263-70.
24. Stolzengerg-Solomon RZ, Miller ER III, Maguire MG, Selhub J, Appel LJ. Association of dietary protein intake and coffee consumption with serum homocysteine concentration in an older population. Am J Clin Nutr 1999; 69: 467-75
25. Jacques PF, Bostom AG, Wilson PWF, Rich S, Rosenberg IH, Selhub J. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am J Clin Nutr 2001; 73: 613-21.
26. Hustad S, Ueland PM, Vollset SE et al. Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C 677 T polymorphism. Clin. Chem 2000; 46: 1065-71.
27. Hillmann RS, Steinberg SE. The effect of alcohol on folate metabolism. Annu Rev Med 1982; 33: 345-54.
28. Rimm ER, Willett WC, Hu FB. Folate and vitamine 86 from diet and supplements in relation to risk of coronary heart disease among women. JAMA 1998; 279: 359-64.
29. Hultberg B, Berglund M, Anderson A, Frank A. Elevated plasma homocysteine in alcoholics. Alcohol Clin Exp Res 1993; 17: 687-9.
30. Cravo ML, Gloria LM, Selhub J et al. Hyperhomocystieine in chronic alcoholism: correlation with folate, vitamine B12 and vitamine B6 status. Am J Clin Nutr 1996; 63: 220-4.
31. Marmot M, Brunner E. Alcohol and cardiovascular diseases: the status of the U-shaped curve. BMJ 1991; 303: 565-8.
32. Halsteat CH. Lifestyle effects on homocysteine and alcohol paradox (Editorial). Am J Clin Nutr 2001; 73: 501-2.
33. Folsom AR, Nieto FJ, Mc Govern PG. Propective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms and B vitamines: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 1998; 98: 204-10.
34. Mennen U, Galan P, Potier De Courcy G, Guilland JC. Homocysteine et consommation d'alcool: effet du type de boisson alcoolique. L'etude SU.VI.MAX. Nutr Clin Metab 2002; 16: 355.
35. De Bree A, Vershuren M, Blom HJ, Kromhout D. Association between B vitamine intake and plasma homocysteine concentration in the general Dutch population aged 20-65 y. Am J Clin Nutr 2001; 73: 1027-33.
36. Mayer O, Simon J, Rosolova H. A population study of the influence of beer consumption on folate and homocysteine concentrations. EJ Clin Nutr2001; 55: 605-9.
37. Obbink JR, Fehily AM, Pickering J, El Wood PC, Wermaak WJH. Homocysteine and ischemic heart disease in the Caerphilly cohort. Atherosclerosis 1998; 140: 349-56.
38. Gunadson V, Stansbie D, Scott J, Bowron A, Nicaud V, Humphries S. C 6775 (Thermolabile alamine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. Atherosclerosis 1998; 136: 347-57.
39. Koehler KM, Baumgartner RN, Garry PJ, Allen RH, Stabler SP, Rimm EB. Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use. Am J Clin Nutr 2001; 73: 628-37.
40. Cheng TO. Homocysteine and coronary artery disease. Atherosclerosis 1999; 145: 419
41. De Bree A, Vershuren M, Blom HJ, Kromhout D. Alcohol consumption and plasma homocysteine: what's breving? Int J Epidemiol 2001; 30: 625-6.
42. Vollset SE, Hygard O, Kvale G, Ueland PM, Refsum H. The Hordeland Homocysteine Study: lifestyle and total plasma homocysteine in Western Norway: In: Graham I, Refsum H, Rosenberg IH, Ueland PM. (ed) Homocysteine metabolisme: from basic science to clinical medicine. Kluwer Academie Publishers. Vol. 1; 1997: 177-82.
43. Brenner H, Rothenbacher D, Bode G, Marz W, Hoffmeister A, Koenig W. Coronary heart disease risk reduction in a predominantly beer-drinking population. Epidemiology 2001; 12: 390-5.
44. Van Der Gaag, Ubbink JB, Sillanaukee P, Nikkari S, Hendriks HFJ. Effect of consumption of red wine, spirits, and beer on serun homocysteine. Lancet 2000; 355: 1522.
45. Bleich S, Bleich K, Kropp S et al. Moderate alcohol consumption in social drinkers raises plasma homocysteine levels: a contradiction to the « French Paradox »? Alcohol Alcoholism 2001; 36: 189-92.
46. Bleich S, Degner D, Bandelon B, Von Ahsen N, Ruther E, Kornhuber J. Plasma homocysteine is a predictor of alcohol withdrawal seizures. Neuroreport 2000; 11: 2749-52.