Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population

American Journal of Clinical Nutrition

Volumn 69, Issue 3, 1999, Pages 467-475

  Stolzenberg Solomon, Rachael Z ^a   Miller III, Edgar R ^b   Maguire, Maureen G ^b   Selhub, Jacob ^b   Appel, Lawrence J ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NONE

Author keywords

Coffee; Creatinine; Diet; Elderly; Folic acid; Homocysteine; Observational study; Protein; THcy; Vitamin B 12; Vitamin supplements

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; COPPER; CREATININE; HOMOCYSTEINE; MAGNESIUM; SELENIUM; VITAMIN; ZINC;

ADULT; AGED; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ARTICLE; CARDIOVASCULAR DISEASE; COFFEE; CREATININE BLOOD LEVEL; DIETARY INTAKE; DOSE RESPONSE; FEMALE; FOLLOW UP; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NUTRITIONAL STATUS; PROTEIN INTAKE; RISK FACTOR; VITAMIN SUPPLEMENTATION;

EID: 0033042879     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/69.3.467     Document Type: Article

References (59)

1. Verhoef P, Stampfer MJ. Prospective studies of homocysteine and cardiovascular disease. Nutr Rev 1995;53:283-8.
2. Ubbink JB. Homocysteine - an atherogenic and a thrombotic factor? Nutr Rev 1995;53:323-5.
3. Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease, probable benefits of increasing folic acid intakes. JAMA 1995;274:1049-57.
4. Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med 1991;324:1149-55.
5. Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA 1997;277:1775-81.
6. Smythies JR, Gottfries CG, Regland B. Disturbances of one carbon metabolism in neuropsychiatric disorders: a review. Biol Psychiatry 1997:41:230-3.
7. Rosenquist TH, Ratashak SA, Sehlub J. Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid. Proc Natl Acad Sci U S A 1996;93:15227-32.
8. Mills JL, McPartlin JM, Kirke PN, et al. Homocysteine metabolism in pregnancies complicated by neural tube defects. Lancet 1995;345:149-51.
9. Steegers-Theunissen RPM, Boers GHJ, Trijbels FJM, et al. Maternal homocysteinemia: a risk factor for neural tube defects? Metabolism 1994;43:1475-80.
10. Ubbink JB, Vermaak WJ, van der Merwe A, Becker PJ. Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 1993;57:47-53.
11. Green R, Jacobsen DW. Clinical implications of hyperhomocysteinemia. In: Bailey LB, ed. Folate in health and disease. New York: Marcel Dekker, 1995:75-122.
12. Selhub J, Jaques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993;270:2693-8.
13. Shimakawa T, Nieto FJ, Malinow MR, Chambless LE, Schreiner PJ, Szklo M. Vitamin intake: a possible determinant of plasma homocysttetine among middle-aged adults. Ann Epidemiol 1997;7: 285-93.
14. Finkelstein JD, Kyle WE, Harris BJ. Methionine metabolism in mammals. Regulation of homocysteine methyltransferase in rat tissue. Arch Biochem Biophys 1971;146:84-92.
15. Sehlub J, Rosenberg IH. Folic acid. In: Ziegler EE, Filer LJ, eds. Present knowledge in nutrition. 7th ed. Washington, DC: ILSI Press, 1996:206-19.
16. Kang SS, Zhou J, Wong PWK, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: a thermolabile variate of methylenetetrahydrofolate reductase. Am J Hum Genet 1988;43:414-21.
17. Guttormsen AB, Ueland PM, Nesthus I, et al. Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (≥40 μmol/liter), the Hordaland Homocysteine Study. J Clin Invest 1996;98:2174-83.
18. Kluijtmans LA, van den Heuvel LPWJ, Boers GHJ, et al. Molecular genetic analysis in mild hyperhomocysteinemia: a commun mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 1996;58:35-41.
19. Boers GHJ, Smals AGH, Trijbels JMF, et al. Heterozygosity for homocysteinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med 1985:313:709-15.
20. Mudd HS, Havlik R, Levy HL, Mckusick VA, Feinleib M. A study of cardiovascular risk in heterozygotes for homocysteinuria. Am J Hum Genet 1981;33:883-93.
21. Kang SS, Wong PWK, Susmano A, Soro J, Norusis M, Ruggie N. Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary heart disease. Am J Hum Genet 1991;48: 536-45.
22. Kang SS, Passen EL, Ruggie N, Wong PWK, Sora H. Thermolabile defect of methylenetetrahydrofolate reductase in coronary heart disease. Circulation 1993;88:1463-9.
23. Frosst P, Blom HJ, Sheppard CA, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-3.
24. Brattstrom L, Lindgren A, Israelesson B, Andersson A, Hultberg B. Homocysteine and cysteine: determinants of plasma levels in middle-aged and elderly subjects. J Intern Med 1994;236:633-41.
25. Lussier-Cacan S, Xhignesse M, Piolot A, Selhub J, Davignon J, Genest J Jr. Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits. Am J Clin Nutr 1996;64:587-93.
26. Nygård O, Vollset SE, Refsum H, et al. Total plasma homocysteine and cardiovascular risk profile, the Hordaland Homocysteine Study. JAMA 1995;274:1526-33.
27. Cravo ML, Gloria LM, Selhub J, et al. Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status. Am J Clin Nutr 1996;63:220-4.
28. Nygård O, Refsum H, Ueland PM, et al. Coffee consumption and plasma total homocysteine: the Hordaland Homocysteine Study. Am J Clin Nutr 1997;65:136-43.
29. Block G, Hartman AM, Dresser CM, Carroll MD, Cannon J, Gardner L. A data-based approach to diet questionnaire design and testing. Am J Epidemiol 1986;124:452-69.
30. Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 1987;422:43-52.
31. Willett W, Stampfer MJ. Total energy intake: implications for epidemiologic analyses. Am J Epidemiol 1986;124:17-27.
32. Glynn SA, Albanes D, Pietinen P, et al. Colorectal cancer and folate status: a nested case-control study among smokers. Cancer Epidemiol Biomarkers Prev 1996;5:487-94.
33. Reeds PJ, Beckett PR. Protein and amino acids. In: Ziegler EE, Filer LJ, eds. Present knowledge in nutrition. 7th ed. Washington, DC: ILSI Press, 1996:67-86.
34. Finkelstein JD, Martin JJ. Methionine metabolism in mammals, adaptation to excess. J Biol Chem 1986;261:1582-7.
35. Finkelstein JD, Kyle WE, Martin JJ, Pick AM. Activation of cystathionine synthase by adenosylmethionine and adenosylethionine. Biochem Biophys Res Commun 1975;66:81-7.
36. Finkelstein JD. Methionine metabolism in mammals. J Nutr Biochem 1990;1:228-37.
37. Andersson A, Brattstrom L, Israelsson B, Isaksson A, Hultberg B. The effect of excess daily methionine intake on plasma homocysteine after methionine loading test in humans. Clin Chim Acta 1990;192:69-76.
38. Stamler J, Caggiula AW, Grandits GA. Chapter 12. Relation of body mass and alcohol, nutrient, fiber, and caffeine intakes to blood pressure in the special intervention and usual care groups in the Multiple Risk Factor Intervention Trial. Am J Clin Nutr 1997;65 (suppl):338S-65S.
39. Stamler J, Elliott P, Kesteloot H, et al. Inverse relation of dietary protein markers with blood pressure: findings for 10,020 men and women in the INTERSALT Study. Circulation 1996;94:1629-34.
40. Giuvanucci E, Stampfer MJ, Colditz GA, et al. Folate, methionine, and alcohol intake and risk of colorectal adenoma. J Natl Cancer Inst 1993;11:875-84.
41. Newberne PM, Rogers AE. Labile methyl groups and the promotion of cancer. Annu Rev Nutr 1986;6:407-32.
42. Shaw GM, Valie EM, Schaffer DM. Is dietary methionine associated with a reduction in the risk of neural tube defect-affected pregnancies? Teratology 1997;56:295-9.
43. Vanaerts LAGJM, Blom HJ, Deabreu RA, et al. Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos. Teratology 1994;50:348-60.
44. Eaton SB, Eaton SB, Konner MJ. Paleolithic nutrition revisited: a twelve-year retrospective on its nature and implications. Eur J Clin Nutr 1997;51:207-16.
45. Rimm EB, Willett WC, Hu FB, et al. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA 1998;279:359-64.
46. Carmel R, Cobalamin, the stomach, and aging. Am J Clin Nutr 1997;66:750-9.
47. Herbert V, Vitamin B12, In: Ziegler EE, Filer LJ, eds. Present knowledge in nutrition. 7th ed. Washington, DC: ILSI Press, 1996:191-205.
48. Lindenbaum J, Rosenberg IH, Wilson PWF, Stabler SP, Allen R. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994;60:2-11.
49. Stabler SP, Lindenbaum J, Allen RH, Vitamin B-12 deficiency in the elderly: current dilemmas. Am J Clin Nutr 1997;66:741-9.
50. Herbert V, Das KC. Folic acid and vitamin B12. In: Shils ME, Olson JA, Shike M, eds. Modern nutrition in health and disease. Baltimore: Lea and Febiger, 1994:402-25.
51. Suter PM, Golner BB, Goldin BR, Morrow FD, Russell RM. Reversal of protein-bound vitamin B12 malabsorption with antibiotics in atrophic gastritis. Gastroenterology 1991;101:1039-45.
52. Tucker KL, Jacques PF, Rosenberg IH, Rich S, Wilson WF, Sehlub J. Relationship between vitamin B12 source and prevalence of low plasma B12 in the Framingham Offspring Study. FASEB J 1998;12:A334 (abstr).
53. Nieto FJ, Comstock GW, Chambless LE, Malinow RM. Coffee consumption and plasma homocyst(e)ine: results from the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 1997;66:1475-6 (letter).
54. Gordis L. From association to causation: deriving inferences from epidemiologic studies. In: Epidemiology. Philadelphia: WB Saunders Company, 1996:170-1.
55. Van der Mooren MJ, Wouter MGAJ, Blom HJ, Schellekens LA, Eskes TKAB, Rolland R. Hormone replacement therapy may reduce high serum homocysteine in postmenopausal women. Eur J Clin Invest 1994;24:733-6.
56. Lien EA, Anker G, Lonning PE, Refsum H, Ueland PM. Effects of hormones on the plasma levels of the atherogenic amino acid homocysteine. Biochem Soc Trans 1997;25:33-5.
57. Koehler KM, Romero LJ, Stauber PM, et al. Vitamin supplementation and other variables affecting serum homocysteine and methylmalonic acid concentrations in elderly men and women. J Am Coll Nutr 1996;15:364-76.
58. Pancharuniti N, Lewis CA, Sauberlich HE, et al. Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease. Am J Clin Nutr 1994;59:940-8.
59. Lewis CA, Pancharuniti N, Sauberlich HE. Plasma folate adequacy as determined by homocysteine level. Ann N Y Acad Sci 1992;669:360-2.