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Volumn 12, Issue 2, 2003, Pages 111-123

Haplotype analysis of the CETP gene: Not taqIB, but the closely linked - 629→A polymorphism and a novel promoter variant are independently associated with CETP concentration

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; CHOLESTEROL ESTER TRANSFER PROTEIN; DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PRAVASTATIN; TRIACYLGLYCEROL;

EID: 0037439546     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg013     Document Type: Review
Times cited : (116)

References (56)
  • 1
    • 0027275449 scopus 로고
    • Plasma cholesteryl ester transfer protein
    • Tall, A.R. (1993) Plasma cholesteryl ester transfer protein. J. Lipid Res., 34, 1255-1274.
    • (1993) J. Lipid Res. , vol.34 , pp. 1255-1274
    • Tall, A.R.1
  • 2
    • 0028135441 scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol
    • Inazu, A., Jiang, X.C., Haraki, T., Yagi, K., Kamon, N., Koizumi, J., Mabuchi, H., Takeda, R., Takata, K. and Moriyama, Y. (1994) Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol. J. Clin. Invest., 94, 1872-1882.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1872-1882
    • Inazu, A.1    Jiang, X.C.2    Haraki, T.3    Yagi, K.4    Kamon, N.5    Koizumi, J.6    Mabuchi, H.7    Takeda, R.8    Takata, K.9    Moriyama, Y.10
  • 3
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong, S., Sharp, D.S., Grove, J.S., Bruce, C., Yano, K., Curb, J.D. and Tall, A.R. (1996) Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J. Clin. Invest., 97, 2917-2923.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3    Bruce, C.4    Yano, K.5    Curb, J.D.6    Tall, A.R.7
  • 4
    • 0033663459 scopus 로고    scopus 로고
    • Pros and cons of inhibiting cholesteryl ester transfer protein
    • Hirano, K., Yamashita, S. and Matsuzawa, Y. (2000) Pros and cons of inhibiting cholesteryl ester transfer protein. Curr. Opin. Lipidol., 11, 589-596.
    • (2000) Curr. Opin. Lipidol. , vol.11 , pp. 589-596
    • Hirano, K.1    Yamashita, S.2    Matsuzawa, Y.3
  • 6
    • 0031844056 scopus 로고    scopus 로고
    • Plasma lipid transfer proteins, high-density lipoproteins, and reverse cholesterol transport
    • Bruce, C., Chouinard, R.A., Jr and Tall, A.R. (1998) Plasma lipid transfer proteins, high-density lipoproteins, and reverse cholesterol transport. A. Rev. Nutr., 18, 297-330.
    • (1998) A. Rev. Nutr. , vol.18 , pp. 297-330
    • Bruce, C.1    Chouinard R.A., Jr.2    Tall, A.R.3
  • 7
    • 0034672713 scopus 로고    scopus 로고
    • Molecular biology and pathophysiological aspects of plasma cholesteryl ester transfer protein
    • 1529
    • Yamashita, S., Hirano, K., Sakai, N. and Matsuzawa, Y. (2000) Molecular biology and pathophysiological aspects of plasma cholesteryl ester transfer protein. Biochim. Biophys. Acta, 1529, 257-275.
    • (2000) Biochim. Biophys. Acta , pp. 257-275
    • Yamashita, S.1    Hirano, K.2    Sakai, N.3    Matsuzawa, Y.4
  • 8
    • 0023650989 scopus 로고
    • Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus
    • Drayna, D. and Lawn, R. (1987) Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus. Nucl. Acids Res., 15, 4698.
    • (1987) Nucl. Acids Res. , vol.15 , pp. 4698
    • Drayna, D.1    Lawn, R.2
  • 9
    • 0001445065 scopus 로고
    • Identification of mutations in the cholesteryl ester transfer protein in Europeans with elevated high density lipoprotein cholesterol
    • Funke, H., Wiebusch, H., Fuer, L., Muntoni, S., Schulte, H. and Assmann, G. (1994) Identification of mutations in the cholesteryl ester transfer protein in Europeans with elevated high density lipoprotein cholesterol. Circulation, 90, I-241.
    • (1994) Circulation , vol.90
    • Funke, H.1    Wiebusch, H.2    Fuer, L.3    Muntoni, S.4    Schulte, H.5    Assmann, G.6
  • 10
    • 0029091283 scopus 로고
    • Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction
    • Fumeron, F., Betoulle, D., Luc, G., Behague, I., Ricard, S., Poirier, O., Jemaa, R., Evans, A., Arveiler, D. and Marques-Vidal, P. (1995) Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction. J. Clin. Invest., 96, 1664-1671.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1664-1671
    • Fumeron, F.1    Betoulle, D.2    Luc, G.3    Behague, I.4    Ricard, S.5    Poirier, O.6    Jemaa, R.7    Evans, A.8    Arveiler, D.9    Marques-Vidal, P.10
  • 11
    • 0033945005 scopus 로고    scopus 로고
    • Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction
    • Corbex, M., Poirier, O., Fumeron, F., Betoulle, D., Evans, A., Ruidavets, J.B., Arveiler, D., Luc, G., Tiret, L. and Cambien, F. (2000) Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction. Genet. Epidemiol., 19, 64-80.
    • (2000) Genet. Epidemiol. , vol.19 , pp. 64-80
    • Corbex, M.1    Poirier, O.2    Fumeron, F.3    Betoulle, D.4    Evans, A.5    Ruidavets, J.B.6    Arveiler, D.7    Luc, G.8    Tiret, L.9    Cambien, F.10
  • 12
    • 0028177421 scopus 로고
    • Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity
    • Freeman, D.J., Griffin, B.A., Holmes, A.P., Lindsay, G.M., Gaffney, D., Packard, C.J. and Shepherd, J. (1994) Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity. Arterioscler. Thromb., 14, 336-344.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 336-344
    • Freeman, D.J.1    Griffin, B.A.2    Holmes, A.P.3    Lindsay, G.M.4    Gaffney, D.5    Packard, C.J.6    Shepherd, J.7
  • 13
    • 0031906444 scopus 로고    scopus 로고
    • Association between plasma HDL-cholesterol concentration and Taq1B CETP gene polymorphism in non-insulin-dependent diabetes mellitus
    • Bernard, S., Moulin, R, Lagrost, L., Picard, S., Elchebly, M., Ponsin, G., Chapuis, F. and Berthezene, F. (1998) Association between plasma HDL-cholesterol concentration and Taq1B CETP gene polymorphism in non-insulin-dependent diabetes mellitus. J. Lipid Res., 39, 59-65.
    • (1998) J. Lipid Res. , vol.39 , pp. 59-65
    • Bernard, S.1    Moulin, R.2    Lagrost, L.3    Picard, S.4    Elchebly, M.5    Ponsin, G.6    Chapuis, F.7    Berthezene, F.8
  • 14
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • The Regression Growth Evaluation Statin Study Group
    • Kuivenhoven, J.A., Jukema, J.W., Zwinderman, A.H., de Knijff, P., McPherson, R., Bruschke, A.V., Lie, K.I. and Kastelein, J.J.P. (1998) The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group. New Engl. J. Med., 338, 86-93.
    • (1998) New Engl. J. Med. , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1    Jukema, J.W.2    Zwinderman, A.H.3    de Knijff, P.4    McPherson, R.5    Bruschke, A.V.6    Lie, K.I.7    Kastelein, J.J.P.8
  • 15
    • 0033065475 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations
    • The EARS Group
    • Gudnason, V., Kakko, S., Nicaud. V., Savolainen, M.J., Kesaniemi, Y.A., Tahvanainen, E. and Humphries, S. (1999) Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. The EARS Group. Eur. J. Clin. Invest., 29, 116-128.
    • (1999) Eur. J. Clin. Invest. , vol.29 , pp. 116-128
    • Gudnason, V.1    Kakko, S.2    Nicaud, V.3    Savolainen, M.J.4    Kesaniemi, Y.A.5    Tahvanainen, E.6    Humphries, S.7
  • 17
    • 0034941420 scopus 로고    scopus 로고
    • An unsolved mystery of promoter variation in CETP gene and atherosclerosis
    • Inazu, A. and Mabuchi, H. (2001) An unsolved mystery of promoter variation in CETP gene and atherosclerosis. Eur. J. Clin. Invest., 31, 558-559.
    • (2001) Eur. J. Clin. Invest. , vol.31 , pp. 558-559
    • Inazu, A.1    Mabuchi, H.2
  • 18
    • 17144458007 scopus 로고    scopus 로고
    • Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy spanish population
    • Corella, D., Saiz, C., Guillen, M., Portoles, O., Mulet, F., Gonzalez, J.I. and Ordovas, J.M. (2000) Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy spanish population. Atherosclerosis, 152, 367-376.
    • (2000) Atherosclerosis , vol.152 , pp. 367-376
    • Corella, D.1    Saiz, C.2    Guillen, M.3    Portoles, O.4    Mulet, F.5    Gonzalez, J.I.6    Ordovas, J.M.7
  • 20
    • 0034946988 scopus 로고    scopus 로고
    • Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness
    • Kakko, S., Tamminen, M., Paivansalo, M., Kauma, H., Rantala, A.O., Lilja, M., Reunanen, A., Kesaniemi, Y.A. and Savolainen, M.J. (2001) Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness. Eur. J. Clin. Invest., 31, 593-602.
    • (2001) Eur. J. Clin. Invest. , vol.31 , pp. 593-602
    • Kakko, S.1    Tamminen, M.2    Paivansalo, M.3    Kauma, H.4    Rantala, A.O.5    Lilja, M.6    Reunanen, A.7    Kesaniemi, Y.A.8    Savolainen, M.J.9
  • 22
    • 0028149212 scopus 로고
    • Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers
    • Hannuksela, M.L., Liinamaa, M.J., Kesaniemi, Y.A. and Savolainen, M.J. (1994) Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers. Atherosclerosis, 110, 35-44.
    • (1994) Atherosclerosis , vol.110 , pp. 35-44
    • Hannuksela, M.L.1    Liinamaa, M.J.2    Kesaniemi, Y.A.3    Savolainen, M.J.4
  • 23
    • 0032833701 scopus 로고    scopus 로고
    • Contribution of the cholesteryl ester transfer protein gene TaqIB polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome
    • Vohl, M.C., Lamarche, B., Pascot, A., Leroux, G., Prud'homme, D., Bouchard, C., Nadeau, A. and Despres, J.P. (1999) Contribution of the cholesteryl ester transfer protein gene TaqIB polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome. Int. J. Obes. Relat Metab Disord., 23, 918-925.
    • (1999) Int. J. Obes. Relat. Metab. Disord. , vol.23 , pp. 918-925
    • Vohl, M.C.1    Lamarche, B.2    Pascot, A.3    Leroux, G.4    Prud'homme, D.5    Bouchard, C.6    Nadeau, A.7    Despres, J.P.8
  • 24
    • 0036061676 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial
    • Brousseau, M.E., O'Connor, J.J., Jr, Ordovas, J.M., Collins, D., Otvos, J.D., Massov, T., McNamara, J.R., Rubins, H.B., Robins, S.J. and Schaefer, E.J. (2002) Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial. Arterioscler. Thromb. Vasc. Biol., 22, 1148-1154.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1148-1154
    • Brousseau, M.E.1    O'Connor J.J., Jr.2    Ordovas, J.M.3    Collins, D.4    Otvos, J.D.5    Massov, T.6    McNamara, J.R.7    Rubins, H.B.8    Robins, S.J.9    Schaefer, E.J.10
  • 26
    • 0033951707 scopus 로고    scopus 로고
    • New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: Role of Sp1/Sp3 in transcriptional regulation
    • Dachet, C., Poirier, O., Cambien, F., Chapman, J. and Rouis, M. (2000) New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation. Arterioscler Thromb. Vasc. Biol., 20, 507-515.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 507-515
    • Dachet, C.1    Poirier, O.2    Cambien, F.3    Chapman, J.4    Rouis, M.5
  • 27
    • 0029050796 scopus 로고
    • Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels
    • The Regression Growth Evaluation Statin Study (REGRESS)
    • Jukema, J.W., Bruschke, A.V., van Boven, A.J., Reiber, J.H., Bal, E.T., Zwinderman, A.H., Jansen, H., Boerma, G.J., van Rappard, F.M. and Lie, K.I. (1995) Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels. The Regression Growth Evaluation Statin Study (REGRESS). Circulation, 91, 2528-2540.
    • (1995) Circulation , vol.91 , pp. 2528-2540
    • Jukema, J.W.1    Bruschke, A.V.2    van Boven, A.J.3    Reiber, J.H.4    Bal, E.T.5    Zwinderman, A.H.6    Jansen, H.7    Boerma, G.J.8    van Rappard, F.M.9    Lie, K.I.10
  • 29
    • 0025363021 scopus 로고
    • Characterization of a human apolipoprotein E gene enhancer element and its associated protein factors
    • Chang, D.J., Paik, Y.K., Leren, T.P., Walker, D.W., Howlett, G.J. and Taylor, J.M. (1990) Characterization of a human apolipoprotein E gene enhancer element and its associated protein factors. J. Biol. Chem., 265, 9496-9504.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9496-9504
    • Chang, D.J.1    Paik, Y.K.2    Leren, T.P.3    Walker, D.W.4    Howlett, G.J.5    Taylor, J.M.6
  • 30
    • 0026329407 scopus 로고
    • Similarities and differences in the function of regulatory elements at the 5′ end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells
    • Paulweber, B., Onasch, M.A., Nagy, B.P. and Levy-Wilson, B. (1991) Similarities and differences in the function of regulatory elements at the 5′ end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells. J. Biol. Chem., 266, 24149-24160.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24149-24160
    • Paulweber, B.1    Onasch, M.A.2    Nagy, B.P.3    Levy-Wilson, B.4
  • 32
    • 18344364813 scopus 로고    scopus 로고
    • A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB; and -629C/A polymorphisms
    • Le Goff, W., Guerin, M., Nicaud, V., Dachet, C., Luc, G., Arveiler, D., Ruidavets, J.B., Evans, A., Kee, F., Morrison, C. et al. (2002) A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB; and -629C/A polymorphisms. Atherosclerosis, 161, 269-279.
    • (2002) Atherosclerosis , vol.161 , pp. 269-279
    • Le Goff, W.1    Guerin, M.2    Nicaud, V.3    Dachet, C.4    Luc, G.5    Arveiler, D.6    Ruidavets, J.B.7    Evans, A.8    Kee, F.9    Morrison, C.10
  • 34
    • 0029952738 scopus 로고    scopus 로고
    • Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol
    • Richardson, M.A., Berg, D.T., Johnston, P.A., McClure, D. and Grinnell, B.W. (1996) Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol. J. Lipid Res., 37, 1162-1166.
    • (1996) J. Lipid Res. , vol.37 , pp. 1162-1166
    • Richardson, M.A.1    Berg, D.T.2    Johnston, P.A.3    McClure, D.4    Grinnell, B.W.5
  • 35
    • 0032805208 scopus 로고    scopus 로고
    • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: Functional role of the transcription factors SREBP-1a, -2, and YY1
    • Gauthier, B., Robb, M., Gaudet, F., Ginsburg, G.S. and McPherson, R. (1999) Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. J. Lipid Res., 40, 1284-1293.
    • (1999) J. Lipid Res. , vol.40 , pp. 1284-1293
    • Gauthier, B.1    Robb, M.2    Gaudet, F.3    Ginsburg, G.S.4    McPherson, R.5
  • 36
    • 0033997752 scopus 로고    scopus 로고
    • Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
    • Luo, Y. and Tall, A.R. (2000) Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element. J. Clin. Invest., 105, 513-520.
    • (2000) J. Clin. Invest. , vol.105 , pp. 513-520
    • Luo, Y.1    Tall, A.R.2
  • 37
    • 0035854792 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein biosynthesis and cellular cholesterol homeostasis are tightly interconnected
    • Izem, L. and Morton, R.E. (2001) Cholesteryl ester transfer protein biosynthesis and cellular cholesterol homeostasis are tightly interconnected. J. Biol. Chem., 276, 26534-26541.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26534-26541
    • Izem, L.1    Morton, R.E.2
  • 38
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    • Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K. and Shinkai, H. (2000) A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature, 406, 203-207.
    • (2000) Nature , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 39
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
    • de Grooth, G.J., Kuivenhoven, J.A., Stalenhoef, A.F., de Graaf, J., Zwinderman, A.H., Posma, J.L., van Tol, A. and Kastelein, J.J. (2002) Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation, 105, 2159-2165.
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • de Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.3    de Graaf, J.4    Zwinderman, A.H.5    Posma, J.L.6    van Tol, A.7    Kastelein, J.J.8
  • 40
    • 0035170229 scopus 로고    scopus 로고
    • High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport
    • Von Eckardstein, A., Nofer, J.R. and Assmann, G. (2001) High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscler Thromb. Vasc. Biol., 21, 13-27.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 13-27
    • Von Eckardstein, A.1    Nofer, J.R.2    Assmann, G.3
  • 41
    • 0029988937 scopus 로고    scopus 로고
    • Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis
    • Villard, E., Tiret, L., Visvikis, S., Rakotovao, R., Cambien, F. and Soubrier, F. (1996) Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am. J. Hum. Genet., 58, 1268-1278.
    • (1996) Am. J. Hum. Genet. , vol.58 , pp. 1268-1278
    • Villard, E.1    Tiret, L.2    Visvikis, S.3    Rakotovao, R.4    Cambien, F.5    Soubrier, F.6
  • 43
    • 0034750404 scopus 로고    scopus 로고
    • The -629C > A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men
    • Eiriksdottir, G., Bolla, M.K., Thorsson, B., Sigurdsson, G., Humphries, S.E. and Gudnason, V. (2001) The -629C > A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men. Atherosclerosis, 159, 187-192.
    • (2001) Atherosclerosis , vol.159 , pp. 187-192
    • Eiriksdottir, G.1    Bolla, M.K.2    Thorsson, B.3    Sigurdsson, G.4    Humphries, S.E.5    Gudnason, V.6
  • 45
    • 0026689178 scopus 로고
    • Performing the exact test of Hardy-Weinberg proportion for multiple alleles
    • Guo, S.W. and Thompson, E.A. (1992) Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics, 48, 361-372.
    • (1992) Biometrics , vol.48 , pp. 361-372
    • Guo, S.W.1    Thompson, E.A.2
  • 46
    • 0030131165 scopus 로고    scopus 로고
    • Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm
    • Slatkin, M. and Excoffier, L. (1996) Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm. Heredity, 76 (Pt 4), 377-383.
    • (1996) Heredity , vol.76 , Issue.PART 4 , pp. 377-383
    • Slatkin, M.1    Excoffier, L.2
  • 47
    • 0003402305 scopus 로고    scopus 로고
    • Arlequin ver. 2.000: A Software for Population Genetics Data Analysis
    • Genetics and Biometry Laboratory, University of Geneva, Switzerland
    • Schneider, S., Roessli, D., and Excoffier, L. (2000) Arlequin ver. 2.000: a Software for Population Genetics Data Analysis. Genetics and Biometry Laboratory, University of Geneva, Switzerland.
    • (2000)
    • Schneider, S.1    Roessli, D.2    Excoffier, L.3
  • 48
    • 0023915850 scopus 로고
    • The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes
    • Thompson, E.A., Deeb, S., Walker, D. and Motulsky, A.G. (1988) The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am. J. Hum. Genet., 42, 113-124.
    • (1988) Am. J. Hum. Genet. , vol.42 , pp. 113-124
    • Thompson, E.A.1    Deeb, S.2    Walker, D.3    Motulsky, A.G.4
  • 49
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier, L. and Slatkin, M. (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol., 12, 921-927.
    • (1995) Mol. Biol. Evol. , vol.12 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 50
    • 0023282287 scopus 로고
    • The general relationship between average effect and average excess
    • Templeton, A.R. (1987) The general relationship between average effect and average excess. Genet. Res., 49, 69-70.
    • (1987) Genet. Res. , vol.49 , pp. 69-70
    • Templeton, A.R.1
  • 52
    • 25444532788 scopus 로고    scopus 로고
    • Flexible smoothing with B-splines and penalties
    • Eilers, P.H.C. and Marx, B.D. (1996) Flexible smoothing with B-splines and penalties. Stat. Sci., 11, 89-102.
    • (1996) Stat. Sci. , vol.11 , pp. 89-102
    • Eilers, P.H.C.1    Marx, B.D.2
  • 53
    • 32044449925 scopus 로고
    • Generalized cross-validation as a method for choosing a good ridge parameter
    • Golub, G.H., Heath, M. and Wahba, G. (1979) Generalized cross-validation as a method for choosing a good ridge parameter. Technometrics, 21, 215-223.
    • (1979) Technometrics , vol.21 , pp. 215-223
    • Golub, G.H.1    Heath, M.2    Wahba, G.3
  • 54
    • 0001044972 scopus 로고
    • Finding the observed information matrix when using the EM algorithm
    • Louis, T.A. (1982) Finding the observed information matrix when using the EM algorithm. J. Stat. Soc. Ser. B, 44, 226-233.
    • (1982) J. Stat. Soc. Ser. B , vol.44 , pp. 226-233
    • Louis, T.A.1
  • 55
    • 0000501656 scopus 로고
    • Information theory and an extension of the maximum likelihood principle
    • Problems of Control and Information Theory
    • Akaike, H. (1973) Information theory and an extension of the maximum likelihood principle. Proceeding of 2nd International Symposium on Information Theory, Suppl. Problems of Control and Information Theory, 267-281.
    • (1973) Proceeding of 2nd International Symposium on Information Theory , Issue.SUPPL. , pp. 267-281
    • Akaike, H.1
  • 56
    • 0034738137 scopus 로고    scopus 로고
    • Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size: Use of a novel tetra-nucleotide repeat within the CETP promoter
    • Talmud, P.J., Edwards, K.L., Turner, C.M., Newman, B., Palmen, J.M., Humphries, S.E. and Austin, M.A. (2000) Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size: use of a novel tetra-nucleotide repeat within the CETP promoter. Circulation, 101, 2461-2466.
    • (2000) Circulation , vol.101 , pp. 2461-2466
    • Talmud, P.J.1    Edwards, K.L.2    Turner, C.M.3    Newman, B.4    Palmen, J.M.5    Humphries, S.E.6    Austin, M.A.7


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