Specific haplotypes of the P-selectin gene are associated with myocardial infarction

Human Molecular Genetics

Volumn 11, Issue 17, 2002, Pages 2015-2023

  Tregouet, David Alexandre ^a   Barbaux, Sandrine ^a   Escolano, Sylvie ^a   Tahri, Nadia ^a   Golmard, Jean Louis ^a   Tiret, Laurence ^a   Cambien, François ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CELL ADHESION MOLECULE; DNA; PADGEM PROTEIN;

ADULT; ALLELE; ARTICLE; ATHEROSCLEROSIS; CHROMOSOME VARIANT; CODON; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; FRANCE; GENETIC CODE; GENETIC VARIABILITY; HAPLOTYPE; HEART INFARCTION; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MAXIMUM LIKELIHOOD METHOD; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTECTION; SAMPLE; UNITED KINGDOM; CASE CONTROL STUDY; COMPARATIVE STUDY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED;

ADULT; CASE-CONTROL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; MYOCARDIAL INFARCTION; P-SELECTIN; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0037101844     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/11.17.2015     Document Type: Article

References (30)

1. Mechanisms that regulate the functions of the Selectins and their ligands
2. Absence of p-selectin, but not intercellular adhesion molecule-1, attenuates neointimal growth after arterial injury in apolipoprotein e-deficient mice
3. Increased soluble form of P-selectin in patients with unstable angina
4. P-selectin expression on platelets determines size and stability of platelet aggregates
5. Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease
6. The P-selectin gene is highly polymorphic: Reduced frequency of the Pro715 allele carriers in patients with myocardial infarction
7. Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction
8. Loss of information due to ambiguous haplotyping of SNPs
9. Sequence variation in the human angiotensin converting enzyme
10. Experimentally-derived haplotypes substantially increase the efficiency of linkage disequilibrium studies
11. Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21
12. Inference of haplotypes from PCR-amplified samples of diploid populations
13. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
14. Maximum-likelihood estimation of molecular haplotype frequencies in diploid population
15. Fine genetic mapping using haplotype analysis and the missing data problem
16. A new statistical method for haplotype reconstruction from population data
17. Characterization of single-nucleotide polymorphisms in coding regions of human genes
18. P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils
19. Mapping the epitope of a functional P-selectin monoclonal antibody (LYP20) to a short complement-like repeat (SCR4) domain: Use of human-mouse chimaera and homologue-replacement mutagenesis
20. Score tests for association between traits and haplotypes when linkage phase is ambiguous
21. The accuracy of statistical methods for estimation of haplotypes frequencies: An example from the CD4 locus
22. Haplotyping and estimation of haplotype frequencies for closely linked biallelic multilocus genetic phenotypes including nuclear family information
23. Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
24. Analysis of enzymatically amplified beta-globin and HLA-DQA alpha DNA with allele-specific oligonucleotide probes
25. Testing for association between disease and linked marker loci: A log-linear-model analysis
26. Testing association between candidate-gene markers and phenotype in related individuals, by use of estimating equations
27. GEMINI: A computed program for optimization of general nonlinear functions
28. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels
29. A parametric copula model for analysis of familial binary data