Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol

Journal of Lipid Research

Volumn 37, Issue 5, 1996, Pages 1162-1166

  Richardson, Mark A ^b   Berg, David T ^b   Johnston, Patricia A ^a   McClure, Don ^b   Grinnell, Brian W ^b  

^a Sphinx Pharmaceuticals Corporation   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

adipocytes; hepatocytes; high density lipoprotein metabolism

Indexed keywords

25 HYDROXYCHOLESTEROL; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PHOSPHOLIPID;

ADIPOCYTE; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; GENE EXPRESSION; HEP 2 CELL; HUMAN; HUMAN CELL; LIPOPROTEIN METABOLISM; LIPOPROTEIN SECRETION; LIPOSARCOMA; LIVER CELL; PRIORITY JOURNAL;

ADIPOCYTES; CARRIER PROTEINS; CELL LINE; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEINS; GLYCOPROTEINS; HUMANS; HYDROXYCHOLESTEROLS; LIPOPROTEINS, LDL; LIPOSARCOMA; RNA, MESSENGER;

EID: 0029952738     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Tall, A. 1995. Plasma lipid transfer proteins. Annu. Rev. Biochem. 64: 235-257.
2. Tall, A. R. 1993. Plasma cholesteryl ester transfer protein. J. Lipid Res. 34: 1255-1274.
3. Lagrost, L. 1994. Regulation of cholesteryl ester transfer protein (CETP) activity: review of in vitro and in vivo studies. Biochim. Biophys. Acta. 1215: 209-236.
4. Swenson, T. L. 1991. The role of the cholesteryl ester transfer protein in lipoprotein metabolism. Diabetes Metab. Rev. 7: 139-153.
5. Evans, G. F., W. R. Bensch, L. D. Apelgren, D. Bailey, R. F. Kauffman, T. F. Bumol, and S. H. Zuckerman. 1994. Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effect of HDL subspecies, quantity, and apolipoprotein distribution. J. Lipid Res. 35: 1634-1645.
6. Whitlock, M. E., T. L. Swenson, R. Ramakrishnan, M. T. Leonard, Y. L. Marcel, R. W. Milne, and A. R. Tall. 1989. Monoclonal antibody inhibition of cholesteryl ester transfer protein activity in the rabbit. J. Clin. Invest. 84: 129-137.
7. Agellon, L. B., A. Walsh, T. Hayek, R. Moulin, X. C. Jiang, S. A. Shelanski, J. L. Breslow, and A. R. Tall. 1991. Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice. J. Biol. Chem. 266: 10796-10801.
8. Marotti, K. R., C. K. Castle, T. P. Boyle, A. H. Lin, R. W. Murray, and G. W. Melchior. 1993. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature. 364: 73-75.
9. Jiang, X. C., L. B. Agellon, A. Walsh, J. A. Breslow, and A. Tall. 1992. Dietary cholesterol increase transcription of the human cholesteryl ester transfer protein gene in transgenic mice. J. Clin. Invest. 90: 1290-1295.
10. Swenson, T. L., J. S. Simmons, C. B. Hesler, C. Bisgaier, and A. R. Tall. 1987. Cholesteryl ester transfer protein is secreted by HepG2 cells and contains asparagine-linked carbohydrate and sialic acid. J. Biol. Chem. 262: 16271-16274.
11. Faust, R. A., and J. J. Albers. 1987. Synthesis and secretion of plasma cholesteryl-ester-transfer protein by human hepatocarcinoma cell line HepG2. Atherosclerosis. 7: 267-275.
12. Sperker, B., M. Mark, and R-M. Budzinski. 1993. The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Eur. J. Biochem. 218: 945-950.
13. Agellon, L. B., P. Zhang, W-C. Jiang, L. Mendelsohn, and A. R. Tall. 1992. The CCAAT/enhancer binding protein Irans activates the human cholesteryl ester transfer gene promoter. J. Biol. Chem. 267: 22336-22339.
14. Jiang, X., P. Moulin, E. Quinet, I. J. Goldberg, L. K. Yacoub, L. B. Agellio, D. Compton, R. Polokoff, and A. R. Tall. 1991. Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA. J. Biol. Chem. 266: 4631-4639.
15. Grinnell, B. W., D. T. Berg, and J. Walls. 1986. Activation of the adenovirus and BK virus late promoters: effects of the BK virus enhancer and trans-acting viral early proteins. Mol. Cell. Biol. 6: 3596-3605.
16. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenolchloroform extraction. Anal. Biochem. 162: 156-159.
17. Tso, J. Y., X. H. Sun, T. H. Kao, K. S. Reece, and R. Wu. 1985. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13: 2485-2502.
18. Quinet, E., T. P. Yang, C. Marinos, and A. Tall. 1993. Inhibition of the cellular secretion of cholesteryl ester transfer protein by a variant protein formed by alternative splicing of mRNA. J. Biol. Chem. 268: 16891-16894.