Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 7, 2002, Pages 1148-1154

  Brousseau, Margaret E ^a   O'Connor Jr , John J ^a   Ordovas, Jose M ^a   Collins, Dorothea ^b   Otvos, James D ^c   Massov, Tatyana ^a   McNamara, Judith R ^a   Rubins, Hanna B ^d   Robins, Sander J ^e   Schaefer, Ernst J ^a  

^a TUFTS UNIVERSITY   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cholesteryl ester transfer protein; Coronary heart disease; High density lipoproteins; Polymorphism; Veterans Affairs HDL C Intervention Trial

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ALLELISM; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; ISCHEMIC HEART DISEASE; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PARTICLE SIZE; PHENOTYPE; PRIORITY JOURNAL; SOLDIER; TANGIER DISEASE;

ALLELES; ANTILIPEMIC AGENTS; APOLIPOPROTEINS; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; CORONARY DISEASE; FASTING; GEMFIBROZIL; GENETIC MARKERS; GENOTYPE; GLYCOPROTEINS; HUMANS; LIPID METABOLISM; LIPID METABOLISM, INBORN ERRORS; LIPIDS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; MOLECULAR WEIGHT; RISK FACTORS; UNITED STATES; UNITED STATES DEPARTMENT OF VETERANS AFFAIRS;

EID: 0036061676     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000024566.57589.2E     Document Type: Article

References (52)

1. Plasma high density lipoprotein concentration and development of ischaemic heart-disease
2. High density lipoprotein cholesterol and cardiovascular disease: Four prospective American studies
3. A prospective study of cholesterol, apoproteins and the risk of myocardial infarction
4. Isolated low HDL cholesterol as a risk factor for coronary heart disease
5. The plasma lecithin: Cholesterol acyltransferase reaction
6. Plasma lipid transfer proteins, high density lipoproteins, and reverse cholesterol transport
7. Cloning and sequencing of human cholesteryl ester transfer protein cDNA
8. Organization of the human cholesteryl ester transfer protein gene
9. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
10. Serum lipoprotein lipid concentration and composition in homozygous and heterozygous patients with cholesteryl ester transfer protein deficiency
11. Compound heterozygote of cholesteryl-ester transfer protein deficiency in a patient with hyperalphalipoproteinemia
12. Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol
13. Identification of mutations in the cholesteryl ester transfer protein in Europeans with elevated high density lipoprotein cholesterol
14. Mutations in cholesteryl ester transfer protein and hepatic lipase in a North American population
15. Human plasma CETP deficiency: Identification of a novel mutation in exon 9 of the CETP gene in a Caucasian subject from North America
16. Plasma lipid transfer proteins
17. Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency
18. Increased catabolic rate of low density lipoproteins in humans with cholesteryl ester transfer protein deficiency
19. R451Q mutation in the cholesteryl ester transfer protein (CETP) gene is associated with high plasma CETP activity
20. Common cholesteryl ester transfer protein mutations, decreased HDL cholesterol, and possible decreased risk of ischemic heart disease: The Copenhagen City Heart Study
21. Heterogeneity at the CETP gene locus: Influence on plasma CETP concentrations and HDL cholesterol levels
22. Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene
23. Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus
24. DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels
25. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors: Associations between the TaqI B RFLP in the CETP gene and smoking and obesity
26. Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers
27. New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: Role of Sp1/Sp3 in transcriptional regulation
28. The -629C>A polymorphism in the CETP gene does not explain the association of the TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men
29. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
30. Polymorphisms of the gene encoding cholesterol ester transfer protein and serum lipoprotein levels in subjects with and without coronary heart disease
31. Polymorphisms of the gene encoding cholesteryl ester transfer protein and plasma lipid levels in Italian and Greek migrants to Australia
32. Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction
33. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis: The Regression Growth Evaluation Statin Study Group
34. Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: The Framingham study
35. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high density lipoprotein cholesterol
36. Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions
37. 2+ precipitation procedure for quantitation of high-density lipoprotein cholesterol
38. Improved methods for separation of total HDL and subclasses
39. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
40. Reference intervals for plasma apolipoprotein A-I determined with a standardized commercial immunoturbidimetric assay: Results from the Framingham Offspring Study
41. Reference intervals for plasma apolipoprotein B determined with a standardized commercial immunoturbidimetric assay: Results from the Framingham Offspring Study
42. Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement
43. Measurement of lipoprotein subclass profile by nuclear magnetic resonance
44. The new pathophysiology of coronary artery disease
45. Familial lipoprotein disorders in patients with premature coronary artery disease
46. Genetic and environmental influences on serum lipid levels in twins
47. Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors
48. Low-density and high-density lipoprotein subspecies and risk for premature coronary artery disease
49. Clinical significance oflipoprotein size and risk for coronary atherosclerosis
50. Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size
51. A prospective study of triglycerides, low-density lipoprotein particle diameter, and risk of myocardial infarction
52. Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women