Regulation of the calcium channel α(1G) subunit by divalent cations and organic blockers

Neuropharmacology

Volumn 39, Issue 7, 2000, Pages 1254-1266

  Lacinova L ^a   Klugbauer, N ^a   Hofmann, F ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antiepileptics; Cadmium; Dihydropyridines; Mibefradil; Nickel; T type calcium channel

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; AMILORIDE; ANTICONVULSIVE AGENT; CADMIUM; CALCIUM CHANNEL; DIHYDROPYRIDINE DERIVATIVE; DIVALENT CATION; ETHOSUXIMIDE; ISRADIPINE; MIBEFRADIL; NICKEL; NIFEDIPINE; PHENYTOIN; RECEPTOR SUBUNIT; TETRODOTOXIN; VALPROIC ACID;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; GENETIC TRANSFECTION; KINETICS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SENSORY NERVE CELL;

CADMIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CATIONS; CELL LINE; DIHYDROPYRIDINES; ELECTROPHYSIOLOGY; HUMANS; KIDNEY; MIBEFRADIL; NICKEL; PATCH-CLAMP TECHNIQUES; TRANSFECTION;

EID: 0034018917     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00202-6     Document Type: Article

References (40)

1. Aggarwal R., Shorofsky S.R., Goldman L., Balke C.W. Tetrodotoxin-blockable calcium currents in rat ventricular myocytes; a third type of cardiac cell sodium current. Journal of Physiology. 505:1997;353-369.
2. Akaike N., Kostyuk P.G., Osipchuk Y.V. Dihydropyridine-sensitive low-threshold calcium channels in isolated rat hypothalamic neurones. Journal of Physiology. 412:1989;181-195.
3. 2+ current of mouse spermatogenic cells. Molecular Pharmacology. 53:1998;1104-1111.
4. Balke C.W., Goldman L., Aggarwal R., Shorofsky S.R. Whether "slip-mode conductance" occurs. Science. 284:1999;711a.
5. Bangalore R., Baindur N., Rutledge A., Triggle D.J., Kass R.S. L-type calcium channels - asymmetrical intramembrane binding domain revealed by variable length permanently charged 1,4-dihydropyridines. Molecular Pharmacology. 46:1994;660-666.
6. 2+ channel antagonist mibefradil (Ro 40-5967). Molecular Pharmacology. 48:1995;540-549.
7. Clozel J.P., Ertel E.A., Ertel S.I. Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker. Journal of Hypertension. 15:1997;S17-S25.
8. Coulter D.A., Huguenard J.R., Prince D.A. Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons. Annals of Neurology. 25:1989;582-593.
9. Coulter D.A., Huguenard J.R., Prince D.A. Specific petit mal anticonvulsants reduce calcium currents in thalamic neurons. Neuroscience Letters. 98:1989;74-78.
10. Coulter D.A., Huguenard J.R., Prince D.A. Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction. British Journal of Pharmacology. 100:1990;800-806.
11. 2+ channel gene family. Circulation Research. 83:1998;103-109.
12. Huguenard J.R. Low-threshold calcium currents in central nervous system neurons. Annual Review of Physiology. 58:1996;329-348.
13. Huguenard J.R., Prince D.A. Intrathalamic rythmicity studied in vitro: nominal T-current modulation causes robust antioscillatory effects. Journal of Neuroscience. 14:1994;5485-5502.
14. Kim H.Ch., Chung M.K. Voltage-dependent sodium and calcium current in acutely isolated adult rat trigeminal root ganglion neurons. Journal of Neurophysiology. 81:1999;1123-1134.
15. Klugbauer N., Marais E., Lacinová L., Hofmann F. A T-type calcium channel from mouse brain. Pflügers Archives. 437:1999;710-715.
16. 2+ channels in rat aorta smooth muscle cells in primary culture. Circulation Research. 76:1990;469-480.
17. 1-subunit of the cardiac L-type calcium channel. Journal of Pharmacology and Experimental Therapeutics. 274:1995;54-63.
18. Lacinová L., An R.H., Xia J., Ito H., Klugbauer N., Sokol L., Triggle D., Hofmann F., Kass R.S. Distinction in the molecular determinants of charged and neutral dihydropyridine block of L-type calcium channels. Journal of Pharmacology and Experimental Therapeutics. 289:1999;1472-1479.
19. Lee J.-H., Daud A.V., Cribbs L.L., Lacerda A.E., Pereverzev A., Klöckner U., Schneider T., Perez-Reyes E. Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. Journal of Neuroscience. 19:1999;1912-1921.
20. Leresche N., Parri H.R., Erdemli G., Guyon A., Turner J.P., Williams S.R., Asprodini E., Crunelli V. On the action of the anti-absence drug ethosuximide in the rat and cat thalamus. Journal of Neuroscience. 18:1998;4842-4853.
21. Macdonald, R.L., McLean, M.J., 1986. Anticonvulsant drugs: mechanism of action. Advances in Neurology 44, 713-736. Journal of Neurophysiology 80, 1678-1685.
22. Macdonald, R.L., McLean, M.J., 1986. Anticonvulsant drugs: mechanism of action. Advances in Neurology 44, 713-736. Journal of Neurophysiology 80, 1678-1685.
23. Macdonald R.L., Kelley K.M. Antiepileptic drug mechanisms of action. Epilepsia. 36(Suppl. 2):1995;S2-S12.
24. McDonough S.I., Bean B.P. Mibefradil inhibition of T-type calcium channels in cerebellar Purkinje neurons. Molecular Pharmacology. 54:1998;1080-1087.
25. McFarlane M.B., Gilly W.F. State-dependent Nickel Block of a High-voltage-activated Neuronal Calcium Channel. 1998.
26. 2+ channels. Journal of Pharmacology and Experimental Therapeutics. 271:1994;1483-1488.
27. Perez-Reyes E., Cribbs L.L., Daud A., Lacerda A.E., Barclay J., Williamson M.P., Fox M., Rees M., Lee J.-H. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Nature. 391:1998;896-899.
28. Randall A.D., Tsien R.W. Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels. Neuropharmacology. 36:1997;879-893.
29. Richard S., Diochot S., Nargeot J., Baldy-Moulinier M., Valmier J. Inhibition of T-type calcium currents by dihydropyridines in mouse embryonic dorsal root ganglion neurons. Neuroscience Letters. 132:1991;229-234.
30. Sayer R.J., Brown A.M., Schwindt P.C., Crill W.E. Calcium currents in acutely isolated human neocortical neurons. Journal of Neurophysiology. 69:1993;1596-1606.
31. 2+ channels in neuroblastoma-glioma hybrid cells. European Journal of Pharmacology. 342:1998;339-345.
32. Talley E.M., Cribbs L.L., Lee J.-H., Daud A., Perez-Reyes E., Bayliss D.A. Differential distribution of three members of a gene family encoding low voltage-activated T-type calcium channels. Journal of Neuroscience. 19:1999;1895-1911.
33. Tang C.-H., Presser F., Morad M. Amilorid selectively blocks the low threshold (T) calcium channel. Science. 240:1988;213-215.
34. 2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. Journal of Neurophysiology. 79:1998;240-252.
35. Tsakiridou E., Bertollini L., De Curtis M., Avanzini G., Pape H. Selective increase in T-type calcium conductance in reticular thalamic neurons in a rat model of absence epilepsy. Journal of Neuroscience. 15:1995;3110-3117.
36. Twombly D.A., Yoshii M., Narahashi T. Mechanisms of calcium channel block by phenytoin. Journal of Pharmacology and Experimental Therapeutics. 246:1988;189-195.
37. Vasssort G., Alvarez J. Cardiac T-type calcium current: pharmacology and roles in cardiac tissues. Journal of Cardiovascular Electrophysiology. 5:1994;376-393.
38. Williams M.E., Washburn M.S., Hans M., Urrutia A., Brust P.F., Prodanovich P., Harpold M.M., Stauderman K.A. Structure and functional characterization of a novel human low-voltage activated calcium channel. Journal of Neurochemistry. 72:1999;791-799.
39. Yaari Y., Hamon B., Lux H.D. Development of two types of calcium channels in cultured mammalian hippocampal neurons. Science. 235:1987;680-682.
40. Zamponi G.W., Bourinet E., Snutch T.P. Nickel block of a family of neuronal calcium channels: subtype- and subunit-dependent action at multiple sites. Journal of Membrane Biology. 151:1996;77-90.