The sustained inward current and inward rectifier K+ current in pacemaker cells dissociated from rat sinoatrial node

Journal of Physiology

Volumn 523, Issue 3, 2000, Pages 593-605

  Shinagawa, Yasuko ^a   Satoh, Hiroyasu ^a   Noma, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BARIUM ION; CALCIUM CHANNEL L TYPE; INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOPRENALINE; NICARDIPINE; TETRODOTOXIN; 1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; CALCIUM ION; CESIUM ION; POTASSIUM ION;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEEDBACK SYSTEM; HYPERPOLARIZATION; MEMBRANE DEPOLARIZATION; NONHUMAN; PACEMAKER NERVE CELL; PRIORITY JOURNAL; RAT; SINUS NODE; SPONTANEOUS ACTION POTENTIAL; CALCIUM CURRENT; HEART ATRIUM PACEMAKER; POTASSIUM CURRENT; RABBIT; SODIUM CURRENT;

ACTION POTENTIALS; ANIMALS; BARIUM; CALCIUM; CALCIUM CHANNEL BLOCKERS; CESIUM; ELECTRIC CONDUCTIVITY; ISOPROTERENOL; MYOCARDIAL CONTRACTION; NICARDIPINE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RABBITS; RATS; SINOATRIAL NODE; TETRODOTOXIN;

EID: 0034653485     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2000.t01-2-00593.x     Document Type: Article

References (33)

1. ANUMONWO, J. M. B., FREEMAN, L. C., KWOK, W. M. & KASS, R. S. (1992). Delayed rectification in single cells isolated from guinea pig sinoatrial node. American Journal of Physiology 262, H921-925.
2. BARUSCOTTI, M., DIFRANCESCO, D. & ROBINSON, R. B. (1996). A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells. Journal of Physiology 492, 21-30.
3. BOIS, P. & LENFANT, J. (1990). Isolated cells of the frog sinus venosus: properties of the inward current activated during hyperpolarization. Pflügers Archiv 416, 339-346.
4. BONKE, F. I. M. (1973). Electrotonic spread in the sinoatrial node of the rabbit heart. Pflügers Archiv 339, 17-23.
5. K). Journal of Physiology 479.P, 68P.
6. BROWN, H. F., CLARK, A. & NOBLE, S. J. (1976a). Identification of the pace-maker current in frog atrium. Journal of Physiology 258, 521-545.
7. BROWN, H. F., CLARK, A. & NOBLE, S. J. (1976b). Analyses of the pace-maker and repolarization currents in frog atrial muscle. Journal of Physiology 258, 547-577.
8. BROWN, H. F., GILES, W. & NOBLE, S. (1982). Membrane currents underlying activity in frog sinus venosus. Journal of Physiology 271, 783-816.
9. f) in cells isolated from the rabbit sino-atrial node. Journal of Physiology 377, 61-88.
10. f, in rabbit sino-atrial node myocytes. Experientia 47, 449-452.
11. GILES, W. R. & SHIBATA, E. F. (1985). Voltage clamp of bull-frog cardiac pace-maker cells: a quantitative analysis of potassium currents. Journal of Physiology 368, 265-292.
12. GUO, J., MITSUIYE, T. & NOMA, A. (1997). The sustained inward current in sino-atrial node cells of guinea-pig heart. Pflügers Archiv 433, 390-396.
13. GUO, J. & NOMA, A. (1997). Existence of a low-threshold and sustained inward current in rabbit atrio-ventricular node cells. Japanese Journal of Physiology 47, 355-359.
14. GUO, J., ONO, K. & NOMA, A. (1995). A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells. Journal of Physiology 483, 1-13.
15. HAGIWARA, N., IRISAWA, H. & KAMEYAMA, M. (1988). Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells. Journal of Physiology 395, 233-253.
16. HONJO, H., BOYETT, M. R., KODAMA, I. & TOYAMA, J. (1996). Correlation between electrical activity and the size of rabbit sino-atrial node cells. Journal of Physiology 496, 795-808.
17. HUME, J. R. & GILES, W. (1981). Active and passive electrical properties of single bullfrog atrial cells. Journal of General Physiology 78, 19-42.
18. HUME, J. R. & GILES, W. (1983). Ionic currents in single isolated bullfrog atrial cells. Journal of General Physiology 81, 153-194.
19. IRISAWA, H., BROWN, H. F. & GILES, W. (1993). Cardiac pacemaking in the sino-atrial node. Physiological Reviews 73, 197-227.
20. ISENBERG G. & KLÖCKNER, U. (1982). Calcium tolerant ventricular myocytes prepared by incubation in a 'KB medium'. Pflügers Archiv 395, 6-18.
21. + channel in rabbit sionoatrial node cells. American Journal of Physiology 269, H443-452.
22. MARUOKA, F., NAKASHIMA, Y., TAKANO, M., ONO, K. & NOMA, A. (1994). Cation-dependent gating of the hyperpolarization-activated cation current in the rabbit sino-atrial node cells. Journal of Physiology 477, 423-435.
23. + channels in sinoatrial node cells of guinea-pig heart. Journal of Physiology 521, 69-79.
24. NOBLE, D. & NOBLE, S. J. (1984). A model of sino-atrial node electrical activity based on a modification of the DiFrancesco-Noble (1984) equations. Proceedings of the Royal Society B 222, 295-304.
25. NOMA, A. & IRISAWA, H. (1976). Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method. Pflügers Archiv 364, 45-52.
26. + current in sinoatrial node pacemaker activity. American Journal of Physiology 269, H453-462.
27. OSTERRIEDER, W., YANG, Q.-F. & TRAUTWEIN, W. (1982) Effect of barium on the membrane currents in the rabbit S-A node. Pflügers Archiv 394, 78-84.
28. SEYAMA, I. (1976). Characteristics of the rectifying properties of the sino-atrial node cell of the rabbit. Journal of Physiology 255, 379-397.
29. f in single cells from rabbit sino-atrial node. Journal of Physiology 434, 57-83.
30. VERHEIJCK, E. E., VAN GINNEKEN, A. C. G., BOURIER, J. & BOUMAN, L. N. (1995). Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circulation Research 76, 607-615.
31. 2+ current to electrical activity in sinoatrial nodal myocytes of rabbits. American Journal of Physiology 276, H1064-1077.
32. WILDERS, R., JONGSMA, H. J. & VAN GINNEKEN, A. C. (1991). Pacemaker activity of the rabbit sinoatrial node. A comparison of mathematical models. Biophysical Journal 60, 1202-1216.
33. YANAGIHARA, K., NOMA, A. & IRISAWA, H. (1980). Reconstruction of sino-atrial node pacemaker potential based on the voltage clamp experiments. Japanese Journal of Physiology 30, 841-857.