Alternative core promoters regulate tissue-specific transcription from the autoimmune diabetes-related ICA1 (ICA69) gene locus

Journal of Biological Chemistry

Volumn 278, Issue 2, 2003, Pages 853-863

  Friday, Robert P ^a,b,c   Pietropaolo, Susan L ^a   Profozich, Jennifer ^a   Trucco, Massimo ^a,b   Pietropaolo, Massimo ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; GENETIC ENGINEERING; PATHOLOGY; TISSUE;

GENOMIC STRUCTURE;

GENES;

5' RNA LIGASE; AUTOANTIGEN; COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GENE PRODUCT; ISLET CELL AUTOANTIGEN; LUCIFERASE; RNA LIGASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; ICA1 PROTEIN, HUMAN;

5' UNTRANSLATED REGION; ARTICLE; AUTOIMMUNE DIABETES MELLITUS; BINDING SITE; CAAT SEQUENCE; CELL CULTURE; CONSENSUS SEQUENCE; CPG ISLAND; DIABETES MELLITUS; EXON; GC RICH SEQUENCE; GENE ACTIVITY; GENE AMPLIFICATION; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE STRUCTURE; GENETIC POLYMORPHISM; HEART; HUMAN; HUMAN CELL; ICA1 GENE; INSULIN DEPENDENT DIABETES MELLITUS; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; REPORTER GENE; TATA BOX; TESTIS; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; ANTIBODY SPECIFICITY; CHEMISTRY; CHROMOSOME MAP; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MOLECULAR GENETICS; PHYSIOLOGY;

5' UNTRANSLATED REGIONS; AUTOANTIGENS; BASE SEQUENCE; CHROMOSOME MAPPING; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA, COMPLEMENTARY; EXONS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0037428395     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210175200     Document Type: Article

References (67)

1. Pietropaolo, M., Castaño, L., Babu, S., Buelow, R., Kuo, Y.-L., Martin, S., Martin, A., Powers, A. C., Prochazka, M., Naggert, J., Leiter, E. H., and Eisenbarth, G. S. (1993) J. Clin. Invest. 92, 359-371
2. Karges, W., Pietropaolo, M., Ackerley, C., and Dosch, H.-M. (1996) Diabetes 45, 513-521
3. Pilon, M., Peng, X. R., Spence, A. M., Plasterk, R. H., and Dosch, H.-M. (2000) Mol. Biol. Cell 11, 3277-3288
4. Gaedigk, R., Karges, W., Hui, M. F., Scherer, S. W., and Dosch, H.-M. (1996) Genomics 38, 382-391
5. Karges, W., Gaedigk, R., Hui, M. F., Cheung, R. K., and Dosch, H.-M. (1996) Biochim. Biophys. Acta 1360, 97-101
6. Miyazaki, I., Gaedigk, R., Hui, M. F., Cheung, R. K., Morkowski, J., Rajotte, R. V., and Dosch, H.-M. (1994) Biochim. Biophys. Acta 1227, 101-104
7. Gaedigk, R., Duncan, A. M. V., Miyazaki, I., Robinson, B. H., and Dosch, H.-M. (1994) Cytogenet. Cell Genet. 66, 274-276
8. Stassi, G., Schloot, N., and Pietropaolo, M. (1997) Diabetologia 40, 120-122
9. Martin, S., Kardorf, J., Schulte, B., Lampeter, E. F., Gries, F. A., Melchers, I., Wagner, R., Bertrams, J., Roep, B. O., Pfutzner, A., Pietropaolo, M., and Kolb, H. (1995) Diabetologia 38, 351-355
10. Roep, B. O. (1996) Diabetes 45, 1147-1156
11. Roep, B. O., Duinkerken, G., Schreuder, G. M. Th., Kolb, H., DeVries, R. R. P., and Martin, S. (1996) Eur. J. Immunol. 26, 1285-1289
12. Miyazaki, I., Cheung, R. K., Gaedigk, R., Hui, M. F., Van der Meulen, J., Rajotte, R. V., and Dosch, H.-M. (1995) J. Immunol. 154, 1461-1469
13. Winer, S., Gunaratnam, L., Astsatourov, I., Cheung, R. K., Kubiak, V., Karges, W., Hammond-McKibben, D., Gaedigk, R., Graziano, D., Trucco, M., Becker, D. J., and Dosch, H.-M. (2000) J. Immunol. 165, 4086-4094
14. Karges, W., Hammond-McKibben, D., Gaedigk, R., Shibuya, N., Cheung, R., and Dosch, H. M. (1997) Diabetes 46, 1548-1556
15. Lampasona, V., Ferrari, M., Bosi, E., Pastore, M. R., Bingley, P. J., and Bonifacio, E. (1994) J. Autoimmun. 7, 665-674
16. Chaplin, D. D., and Brownstein, B. H. (1992) in Current Protocols in Molecular Biology (Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K., eds) Unit 6.10, John Wiley and Sons, New York
17. Gardiner-Garden, M., and Frommer, M. (1987) J. Mol. Biol. 196, 261-282
18. Carey, M., and Smale, S. T. (2000) Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
19. Braun, H., Koop, R., Ertmer, A., Nacht, S., and Suske, G. (2001) Nucleic Acids Res. 29, 4994-5000
20. De Luca, P., Majello, B., and Lania, L. (1996) J. Biol. Chem. 271, 8533-8536
21. Hagen, G., Muller, S., Beato, M., and Suske, G. (1994) EMBO J. 13, 3843-3851
22. LeVan, T. D., Bloom, J. W., Bailey, T. J., Karp, C. L., Halonen, M., Martinez, F. D., and Vercelli, D. (2001) J. Immunol. 167, 5838-5844
23. Reusch J. E., and Klemm D. J. (2002) J. Biol. Chem. 277, 1426-1432
24. Choi, R. C., Siow, N. L., Zhu, S. Q., Wan, D. C., Wong, Y. H., and Tsim, K. W. (2001) Mol. Cell. Neurosci. 17, 732-745
25. Cibelli, G., Jungling, S., Schoch, S., Gerdes, H. H., and Thiel, G. (1996) Eur. J. Biochem. 236, 171-179
26. Della Fazia, M. A., Servillo, G., and Sassone-Corsi, P. (1997) FEBS Lett. 410, 22-24
27. Reusch, J. E., Colton, L. A., and Klemm, D. J. (2000) Mol. Cell. Biol. 20, 1008-1020
28. Mayr, B., and Montminy, M. (2001) Nat. Rev. Mol. Cell. Biol. 2, 599-609
29. Du, K., and Montminy, M. (1998) J. Biol. Chem. 273, 32377-32379
30. Pugazhenthi, S., Nesterova, A., Sable, C., Heidenreich, K. A., Boxer, L. M., Heasley, L. E., and Reusch, J. E. (2000) J. Biol. Chem. 14, 10761-10766
31. Tan, Y., Rouse, J., Zhang, A., Cariati, S., Cohen, P., and Comb, M. J. (1996) EMBO J. 15, 4629-4642
32. Yamamoto, K. K., Gonzalez, G. A., Biggs, W. H., III, and Montminy, M. R. (1998) Nature 334, 494-498
33. Xing, J., Ginty, D. D., and Greenberg, M. E. (1996) Science 273, 959-963
34. Sun, P., Enslen, H., Myung, P. S., and Maurer, R. A. (1994) Genes Dev. 8, 2527-2539
35. Matthews, R. P., Guthrie, C. R., Wailes, L. M., Zhao, X., Means, A. R., and McKnight, G. S. (1994) Mol. Cell. Biol. 14, 6107-6116
36. Solimena, M., Spitzenberger, F., Pietropaolo, S., Verkade, P., Habermann, B., Lacas-Gervais, S., Mziaut, H., Trucco, M., and Pietropaolo, M. (2002) Diabetes Metab. Rev. 18, Suppl. 4, 32 (abstr.)
37. Jones, P. A., and Takai, D. (2001) Science 293, 1068-1070
38. Paulsen, M., and Ferguson-Smith, A. C. (2001) J. Pathol. 195, 97-110
39. Pfeifer, K. (2000) Am. J. Hum. Genet. 67, 777-787
40. Siegfried, Z., Eden, S., Mendelsohn, M., Feng, X., Tsuber, B.-Z., and Cedar, H. (1999) Nat. Genet. 22, 203-206
41. Beohar, N., and Kawamoto, S. (1998) J. Biol. Chem. 273, 9168-9178
42. Cao, Y.-X., Jean, J.-C., and Williams, M. C. (2000) Biochem. J. 350, 883-890
43. Lübbert, M., Tobler, A., and Daskalakis, M. (1999) Leukemia (Baltimore) 13, 1420-1427
44. Newell-Price, J., King, P., and Clark, A. J. (2001) Mol. Endocrinol. 15, 338-348
45. Persengiev, S. P., and Kilpatrick, D. L. (1996) Neuroreport 8, 227-231
46. Schwab, J., and Illges, H. (2001) Int. Immunol. 13, 705-711
47. Takizawa, T., Nakashima, K., Namihira, M., Ochiai, W., Uemura, A., Yanagisawa, M., Fujita, N., Nakao, M., and Taga, T. (2001) Dev. Cell 1, 749-758
48. Ross, J. (1995) Microbiol. Rev. 59, 423-450
49. Kozak, M. (1991) J. Cell Biol. 115, 887-903
50. Dibb, N. J. (1993) FEBS Lett. 325, 135-139
51. Duret, L. (2001) Trends Genet. 17, 172-175
52. Hurst, L. D., Brunton, C. F. A., and Smith, N. G. C. (1999) Trends Genet. 15, 437-439
53. Hanke, J., Brett, D., Zastro, I., Aydin, A., Delbrück, S., Lehmann, G., Luft, F., Reich, J., and Bork, P. (1999) Trends Genet. 15, 389-390
54. Carvalho, A. B., and Clark, A. G. (1999) Nature 401, 344
55. Comeron, J. M., and Kreitman, M. (2000) Genetics 156, 1175-1190
56. Davies, J. L., Kawaguchi, Y., Bennett, S. T., Copeman, J. B., Cordell, H. J., Pritchard, L. E., Reed, P. W., Gough, S. C., Jenkins, S. C., Palmer, S. M., Balfour, K. M., Rowe, B. R., Farrall, M., Barnett, A. H., Bain, S. C., and Todd, J. A. (1994) Nature 371, 130-136
57. German, M. (2000) Diabetes Mellitus: A Fundamental and Clinical Text, 2nd Ed. (LeRoith, D., Taylor, S. I., and Olefsky, J. M., eds) pp. 11-19, Lippincott Williams & Wilkins, Philadelphia
58. Lucassen, A. M., Screaton, G. R., Julier, C., Elliott, T. J., Lathrop, M., and Bell, J. I. (1994) Hum. Mol. Genet. 4, 501-506
59. Kennedy, G. C., German, M. S., and Rutter, W. J. (1995) Nat. Genet. 9, 292-298
60. Pugliese, A., Zeller, M., Fernandez, A., Jr., Zalcberg, L. J., Bartlett, R. J., Ricordi, C., Pietropaolo, M., Eisenbarth, G. S., Bennett, S. T., and Patel, D. D. (1997) Nat. Genet. 15, 293-297
61. Egwuagu, C. E., Charukamnoetkanok, P., and Gery, I. (1997) J. Immunol. 159, 3109-3112
62. Sospedra, M., Ferrer-Francesch, X., Dominguez, O., Juan, M., Foz-Sala, M., and Pujol-Borrell, R. (1998) J. Immunol. 161, 5918-5929
63. Smith, K. M., Olson, D. C., Hirose, R., and Hanahan, D. (1997) Int. Immunol. 9, 1355-1365
64. Vafiadis, P., Bennett, S. T., Todd, J. A., Nadeau, J., Grabs, R., Goodyer, C. G., Wickramasinghe, S., Colle, E., and Polychronakos, C. (1997) Nat. Genet. 15, 289-292
65. Werdelin, O., Cordes, U., and Jensen, T. (1998) Scand. J. Immunol. 47, 95-100
66. Pugliese, A., Brown, D., Garza, D., Murchison, D., Zeller, M., Redondo, M., Diez, J., Eisenbarth, G. S., Patel, D. D., and Ricordi, C. (2001) J. Clin. Invest. 107, 555-564
67. Pietropaolo, M., Giannoukakis, N., and Trucco, M. (2002) Nat. Immunol. 3, 335