Why do genes have introns? Recombination might add a new piece to the puzzle

Trends in Genetics

Volumn 17, Issue 4, 2001, Pages 172-175

  Duret, Laurent ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DROSOPHILA MELANOGASTER; GENE FUNCTION; GENE STRUCTURE; GENETIC MODEL; GENETIC RECOMBINATION; HUMAN; INTRON; MOLECULAR EVOLUTION; NATURAL SELECTION; NEUTRAL GENE THEORY; NONHUMAN; PRIORITY JOURNAL; SPLICEOSOME;

DROSOPHILA MELANOGASTER; EUKARYOTA; MELANOGASTER;

EID: 0035313034     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(01)02236-3     Document Type: Review

References (22)

1. The recent origin of spliceosomal introns revisited
2. Intron phylogeny: A new hypothesis
3. Alternative splicing of human genes: More the rule than the exception?
4. Why do genes have introns?
5. Sensitivity of patterns of molecular evolution to alterations in methodology: A critique of Hughes and Yeager
6. Searching for regulatory elements in human noncoding sequences
7. Structure of vertebrate genes: A statistical analysis implicating selection
8. The organization of Drosophila genes
9. The small nucleolar RNAs
10. Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes
11. The effect of linkage on limits to artificial selection
12. Intron size and natural selection
13. The correlation between intron length and recombination in Drosophila. Dynamic equilibrium between mutational and selective forces
14. Genome evolution - The changing sizes of genes
15. Small introns tend to occur in GC-rich regions in some but not all vertebrates
16. Evidence for DNA loss as a determinant of genome size
17. The evolution of recombination: Removing the limits to natural selection
18. Selfish genes, pleiotropy and the origin of recombination
19. Patterns and rates of indel evolution in processed pseudogenes from humans and murids
20. Interspersed repeats and other mementos of transposable elements in mammalian genomes
21. The elevated G and C content at exonic third sites is not evidence against neutralist models of isochore evolution
22. Transposons but not retrotransposons are located preferentially in regions of high recombination rate in Caenorhabditis elegans