8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases

Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2003, Pages 155-160

  Evans, Gary B ^a   Furneaux, Richard H ^a   Gainsford, Graeme J ^a   Hanson, John C ^c   Kicska, Gregory A ^b   Sauve, Antony A ^b   Schramm, Vern L ^b   Tyler, Peter C ^a  

^a CALLAGHAN INNOVATION   (New Zealand)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 AZAIMMUCILLIN; ADENOSINE; ENZYME INHIBITOR; INOSINE; NUCLEOSIDE HYDROLASE INHIBITOR; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DISSOCIATION CONSTANT; ENZYME INHIBITION; EQUILIBRIUM CONSTANT;

ADENOSINE; ANIMALS; AZA COMPOUNDS; CATTLE; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; INOSINE; N-GLYCOSYL HYDROLASES; PURINE NUCLEOSIDES; PURINE-NUCLEOSIDE PHOSPHORYLASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037413528     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0203332     Document Type: Article

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