Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases

Biochemistry

Volumn 36, Issue 12, 1997, Pages 3528-3534

  Parkin, David W ^a,c   Limberg, Gerrit ^b   Tyler, Peter C ^b   Furneaux, Richard H ^b   Chen, Xiang Yang ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

^c INTERNATIONAL LIVESTOCK RESEARCH INSTITUTE   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; IMINORIBITOL; ISOENZYME; NUCLEOSIDASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; CRITHIDIA FASCICULATA; DISSOCIATION CONSTANT; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; NONHUMAN; PH; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI;

ANIMALS; ANTI-INFECTIVE AGENTS; ARABINOSE; DEOXYRIBOSE; DRUG DESIGN; ENZYME INHIBITORS; IMINO FURANOSES; INOSINE; ISOENZYMES; KINETICS; N-GLYCOSYL HYDROLASES; RIBITOL; SUGAR ALCOHOLS; TRYPANOSOMA BRUCEI BRUCEI;

CRITHIDIA FASCICULATA; MAMMALIA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0030956627     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962319v     Document Type: Article

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