메뉴 건너뛰기




Volumn 21, Issue 4, 2003, Pages 574-581

Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-β kinase pathway

Author keywords

Airway epithelium; Cystic fibrosis; Cytokines; Inhibitor of nuclear factor B kinase ; Nuclear factor B

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; DNA; FLUTICASONE; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; PHOSPHOTRANSFERASE; RANTES;

EID: 0037385638     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.03.00031803     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 0028982894 scopus 로고
    • CFTR as a cAMP-dependent regulator of sodium channels
    • Stutts MJ, Canessa CM, Olsen JC, et al. CFTR as a cAMP-dependent regulator of sodium channels. Science 1995; 269: 847-850.
    • (1995) Science , vol.269 , pp. 847-850
    • Stutts, M.J.1    Canessa, C.M.2    Olsen, J.C.3
  • 3
    • 0032770489 scopus 로고    scopus 로고
    • Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients
    • Muhlebach MS, Stewart PW, Leigh MW, Noah TL. Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients. Am J Respir Crit Care Med 1999; 160: 186-191.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 186-191
    • Muhlebach, M.S.1    Stewart, P.W.2    Leigh, M.W.3    Noah, T.L.4
  • 5
    • 0034816052 scopus 로고    scopus 로고
    • Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function
    • Weber AJ, Soong G, Bryan R, Saba S, Prince A. Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function. Am J Physiol Lung Cell Mol Physiol 2001; 281: L71-L78.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.281
    • Weber, A.J.1    Soong, G.2    Bryan, R.3    Saba, S.4    Prince, A.5
  • 6
    • 0030776192 scopus 로고    scopus 로고
    • Altered cytokine production by cystic fibrosis tracheal gland serous cells
    • Kammouni W, Figarella C, Marchand S, Merten M. Altered cytokine production by cystic fibrosis tracheal gland serous cells. Inject Immun 1997; 65: 5176-5183.
    • (1997) Infect. Immun. , vol.65 , pp. 5176-5183
    • Kammouni, W.1    Figarella, C.2    Marchand, S.3    Merten, M.4
  • 7
    • 0032081281 scopus 로고    scopus 로고
    • Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells
    • DiMango E, Ratner AJ, Bryan R, Tabibi S, Prince A. Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J Clin Invest 1998; 101: 2598-2605.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2598-2605
    • DiMango, E.1    Ratner, A.J.2    Bryan, R.3    Tabibi, S.4    Prince, A.5
  • 8
    • 0034997191 scopus 로고    scopus 로고
    • Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines
    • Kube D, Sontich U, Fletcher D, Davis PB. Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines. Am J Physiol Lung Cell Mol Physiol 2001; 280: L493-L502.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.280
    • Kube, D.1    Sontich, U.2    Fletcher, D.3    Davis, P.B.4
  • 9
    • 0031452350 scopus 로고    scopus 로고
    • Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa
    • Heeckeren A, Walenga R, Konstan MW, Bonfield T, Davis PB, Ferkol T. Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J Clin Invest 1997; 100: 2810-2815.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2810-2815
    • Heeckeren, A.1    Walenga, R.2    Konstan, M.W.3    Bonfield, T.4    Davis, P.B.5    Ferkol, T.6
  • 10
    • 0033948763 scopus 로고    scopus 로고
    • Induction of nuclear factor-kappa B by exposure to ozone and inhibition by glucocorticoids
    • Chung KF, Adcock IM. Induction of nuclear factor-kappa B by exposure to ozone and inhibition by glucocorticoids. Methods Enzymol 2000; 319: 551-562.
    • (2000) Methods Enzymol. , vol.319 , pp. 551-562
    • Chung, K.F.1    Adcock, I.M.2
  • 12
    • 0034746919 scopus 로고    scopus 로고
    • NF-kappaB: A key role in inflammatory diseases
    • Tak PP, Firestein GS. NF-kappaB: a key role in inflammatory diseases. J Clin Invest 2001; 107: 7-11.
    • (2001) J. Clin. Invest. , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 13
    • 0026764094 scopus 로고
    • A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: A randomized, double-blind, parallel-group controlled trial
    • Laitinen LA, Laitinen A, Haahtela T. A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. J Allergy Clin Immunol 1992; 90: 32-42.
    • (1992) J. Allergy Clin. Immunol. , vol.90 , pp. 32-42
    • Laitinen, L.A.1    Laitinen, A.2    Haahtela, T.3
  • 14
    • 0031957295 scopus 로고    scopus 로고
    • Current issues for establishing inhaled corticosteroids as the antiinflammatory agents of choice in asthma
    • Barnes PJ. Current issues for establishing inhaled corticosteroids as the antiinflammatory agents of choice in asthma. J Allergy Clin Immunol 1998; 101: S427-S433.
    • (1998) J. Allergy Clin. Immunol. , vol.101
    • Barnes, P.J.1
  • 15
    • 0036770032 scopus 로고    scopus 로고
    • Patient preferences and sensory comparisons of three intranasal corticosteroids for the treatment of allergic rhinitis
    • Bachert C, El-Akkad T. Patient preferences and sensory comparisons of three intranasal corticosteroids for the treatment of allergic rhinitis. Ann Allergy Asthma Immunol 2002; 89: 292-297.
    • (2002) Ann. Allergy Asthma Immunol. , vol.89 , pp. 292-297
    • Bachert, C.1    El-Akkad, T.2
  • 16
    • 0033958495 scopus 로고    scopus 로고
    • Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappaB in asthma
    • Hart L, Lim S, Adcock I, Barnes PJ, Fan Chung K. Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappaB in asthma. Am J Respir Crit care Med 2000; 161: 224-231.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 224-231
    • Hart, L.1    Lim, S.2    Adcock, I.3    Barnes, P.J.4    Fan Chung, K.5
  • 17
    • 0030052682 scopus 로고    scopus 로고
    • Effect of fluticasone propionate on sputum of patients with chronic bronchitis and emphysema
    • Llewellyn-Jones CG, Harris TA, Stockley RA. Effect of fluticasone propionate on sputum of patients with chronic bronchitis and emphysema. Am J Respir Crit Care Med 1996; 153: 616-621.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 616-621
    • Llewellyn-Jones, C.G.1    Harris, T.A.2    Stockley, R.A.3
  • 18
    • 0031957726 scopus 로고    scopus 로고
    • Development of fluticasone propionate and comparison with other inhaled corticosteroids
    • Johnson M. Development of fluticasone propionate and comparison with other inhaled corticosteroids. J Allergy Clin Immunol 1998; 101: S434-S439.
    • (1998) J. Allergy Clin. Immunol. , vol.101
    • Johnson, M.1
  • 19
    • 0033947619 scopus 로고    scopus 로고
    • Influence of fluticasone and salmeterol on airway effects of inhaled organic dust; an in vivo and ex vivo study
    • Ek A, Palmberg L, Larsson K. Influence of fluticasone and salmeterol on airway effects of inhaled organic dust; an in vivo and ex vivo study. Clin Exp Immunol 2000; 121: 11-16.
    • (2000) Clin. Exp. Immunol. , vol.121 , pp. 11-16
    • Ek, A.1    Palmberg, L.2    Larsson, K.3
  • 20
    • 0030840935 scopus 로고    scopus 로고
    • Allergic rhinitis and inflammation: The effect of nasal corticosteroid therapy
    • Fokkens WJ, Godthelp T, Holm AF, Blom H, Klein-Jan A. Allergic rhinitis and inflammation: the effect of nasal corticosteroid therapy. Allergy, 1997; 52: 29-32.
    • (1997) Allergy , vol.52 , pp. 29-32
    • Fokkens, W.J.1    Godthelp, T.2    Holm, A.F.3    Blom, H.4    Klein-Jan, A.5
  • 21
    • 0032696013 scopus 로고    scopus 로고
    • Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease
    • Culpitt SV, Maziak W, Loukidis S, Nightingale JA, Matthews JL, Barnes PJ. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: 1635-1639.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 1635-1639
    • Culpitt, S.V.1    Maziak, W.2    Loukidis, S.3    Nightingale, J.A.4    Matthews, J.L.5    Barnes, P.J.6
  • 22
    • 0034653569 scopus 로고    scopus 로고
    • High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content
    • Tabary O, Escotte S, Couetil JP, et al. High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content. J Immunol 2000; 164: 3377-3384.
    • (2000) J. Immunol. , vol.164 , pp. 3377-3384
    • Tabary, O.1    Escotte, S.2    Couetil, J.P.3
  • 23
    • 0032813905 scopus 로고    scopus 로고
    • Genistein inhibits constitutive and inducible NFkappaB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells
    • Tabary O, Escotte S, Couetil JP, et al. Genistein inhibits constitutive and inducible NFkappaB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells. Am J Pathol 1999; 155: 473-481.
    • (1999) Am. J. Pathol. , vol.155 , pp. 473-481
    • Tabary, O.1    Escotte, S.2    Couetil, J.P.3
  • 24
    • 0031659351 scopus 로고    scopus 로고
    • Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro
    • Tabary O, Zahm JM, Hinnrasky J, et al. Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro. Am J Pathol 1998; 153: 921-930.
    • (1998) Am. J. Pathol. , vol.153 , pp. 921-930
    • Tabary, O.1    Zahm, J.M.2    Hinnrasky, J.3
  • 25
    • 0036721431 scopus 로고    scopus 로고
    • Fluticasone propionate inhibits lipopolysaccharide-induced proinflammatory response in human cystic fibrosis airway grafts
    • Escotte S, Danel C, Gaillard D, et al. Fluticasone propionate inhibits lipopolysaccharide-induced proinflammatory response in human cystic fibrosis airway grafts. J Pharmacol Exp Ther 2002; 302: 1151-1157.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 1151-1157
    • Escotte, S.1    Danel, C.2    Gaillard, D.3
  • 26
  • 27
    • 0032528433 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha
    • Thomas LH, Friedland JS, Sharland M, Becker S. Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha. J Immunol 1998; 161: 1007-1016.
    • (1998) J. Immunol. , vol.161 , pp. 1007-1016
    • Thomas, L.H.1    Friedland, J.S.2    Sharland, M.3    Becker, S.4
  • 28
    • 0030756166 scopus 로고    scopus 로고
    • Selective up-regulation of cytokine-induced RANTES gene expression in lung epithelial cells by over expression of IkappaBR
    • Ray P, Yang L, Zhang DH, Ghosh SK, Ray A. Selective up-regulation of cytokine-induced RANTES gene expression in lung epithelial cells by over expression of IkappaBR. J Biol Chem 1997; 272: 20191-20197.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20191-20197
    • Ray, P.1    Yang, L.2    Zhang, D.H.3    Ghosh, S.K.4    Ray, A.5
  • 29
    • 0037040901 scopus 로고    scopus 로고
    • A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells
    • Dhawan P, Richmond A. A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J Biol Chem 2002; 277: 7920-7928.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7920-7928
    • Dhawan, P.1    Richmond, A.2
  • 30
    • 0032817772 scopus 로고    scopus 로고
    • Altered respiratory epithelial cell cytokine production in cystic fibrosis
    • Bonfield TL, Konstan MW, Berger M. Altered respiratory epithelial cell cytokine production in cystic fibrosis. J Allergy Clin Immunol 1999; 104: 72-78.
    • (1999) J. Allergy Clin. Immunol. , vol.104 , pp. 72-78
    • Bonfield, T.L.1    Konstan, M.W.2    Berger, M.3
  • 31
    • 0031957726 scopus 로고    scopus 로고
    • Development of fluticasone propionate and comparison with other inhaled corticosteroids
    • Johnson M. Development of fluticasone propionate and comparison with other inhaled corticosteroids. J Allergy Clin Immunol 1998; 101: S434-S439.
    • (1998) J. Allergy Clin. Immunol. , vol.101
    • Johnson, M.1
  • 32
    • 0032982717 scopus 로고    scopus 로고
    • Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: Preferential targeting of NF-kappaB and lack of I-kappaB involvement
    • Adcock IM, Nasuhara Y, Stevens DA, Barnes PJ. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targeting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol 1999; 127: 1003-1011.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 1003-1011
    • Adcock, I.M.1    Nasuhara, Y.2    Stevens, D.A.3    Barnes, P.J.4
  • 34
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
    • DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997; 388: 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 35
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002; 2: 725-734.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 36
    • 0034643170 scopus 로고    scopus 로고
    • NAK is an IkappaB kinase-activating kinase
    • Tojima Y, Fujimoto A, Delhase M, et al. NAK is an IkappaB kinase-activating kinase. Nature 2000; 404: 778-782.
    • (2000) Nature , vol.404 , pp. 778-782
    • Tojima, Y.1    Fujimoto, A.2    Delhase, M.3
  • 37
    • 0031721046 scopus 로고    scopus 로고
    • Inhaled fluticasone reduces sputum inflammatory indices in severe bronchiectasis
    • Tsang KW, Ho PL, Lam WK, et al. Inhaled fluticasone reduces sputum inflammatory indices in severe bronchiectasis. Am J Respir Crit Care Med 1998; 158: 723-727.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 723-727
    • Tsang, K.W.1    Ho, P.L.2    Lam, W.K.3
  • 38
    • 0030883124 scopus 로고    scopus 로고
    • Randomised controlled trial of inhaled corticosteroids (fluticasone propionate) in cystic fibrosis
    • Balfour-Lynn IM, Klein NJ, Dinwiddie R. Randomised controlled trial of inhaled corticosteroids (fluticasone propionate) in cystic fibrosis. Arch Dis Child 1997; 77: 124-130.
    • (1997) Arch. Dis. Child , vol.77 , pp. 124-130
    • Balfour-Lynn, I.M.1    Klein, N.J.2    Dinwiddie, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.