Transcriptional potencies of inhaled glucocorticoids

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 1, 2000, Pages 57-63

  Jaffuel, Dany ^a   Demoly, Pascal ^a,b   Gougat, Claire ^a   Balaguer, Patrick ^a   Mautino, Gisèle ^a   Godard, Philippe ^a   Bousquet, Jean ^a   Mathieu, Marc ^a  

^a INSERM   (France)

^b MONTPELLIER UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; GLUCOCORTICOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RANTES; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ARTICLE; ASTHMA; DRUG MECHANISM; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

EID: 0033943719     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.1.9901006     Document Type: Article

References (35)

1. 1. Jantzen, H., U. Strahle, B. Gloss, F. Stewart, W. Schmid, M. Boshart, R. Miksicek, and G. Schutz. 1987. Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene. Cell 49:29-38.
2. 2. Imai, E., J. Miner, J. Mitchell, K. Yamamoto, and D. Granner. 1993. Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. J. Biol. Chem. 268:5353-5356.
3. 3. Ming, M., W. Chan, T. Wang, K. Roberts, M. Bouvier, S. Lachance, S. Carriere, and J. Chan. 1996. Beta-adrenoceptors and dexamethasone synergistically stimulate the expression of the angiotensinogen gene in opossum kidney cells. Kidney Int. 50:94-101.
4. 4. Nguyen, T., P. Chen, W. Huang, H. Chen, D. Johnson, and J. Polansky. 1998. Gene structure and properties of T1GR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells. J. Biol. Chem. 273:6341-6350.
5. 5. Mak, J., M. Nishikawa, H. Shirasaki, K. Miyayasu, and P. Barnes. 1995. Protective effects of a glucocorticoid on downregulation of pulmonary β2-adrenergic receptors in vivo. J. Clin. Invest. 96:99-106.
6. 6. Meyer, T., J. Carlstedt-Duke, T. Meyer, and D. Starr. 1997. A weak TATA box is a prerequisite for glucocorticoid-dependent repression of the osteocalcin gene. J. Biol. Chem. 272:30709-30714.
7. 7. Philips, A., M. Maira, A. Mullick, M. Chamberland, S. Lesage, P. Hugo, and J. Drouin. 1997. Antagonism between Nur77 and glucocorticoid receptor for control of transcription. Mol. Cell. Biol 17:5952-5959.
8. 8. Ray, A., K. LaForge, and P. Sehgal. 1990. On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion. Mol. Cell. Biol. 10:5736-5746.
9. 9. Cato, A., and E. Wade. 1996. Molecular mechanisms of anti-inflammatory action of glucocorticoids. Bioessays 18:371-378.
10. 10. Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. Lin, R. Heyman, D. Rose, C. Glass, and M. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414.
11. 11. Demoly, P., N. Basset-Séguin, P. Chanez, A. M. Campbell, C. Gauthier-Rouvière, P. Godard, F.-B. Michel, and J. Bousquet. 1992. C-fos proto-oncogene expression in bronchial biopsies of asthmatics. Am. J. Respir. Cell Mol Biol 7:128-133.
12. 12. Adcock, I. M., S. J. Lane, C. R. Brown, T. H. Lee, and P. J. Barnes. 1995. Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma. J. Exp. Med. 182:1951-1958.
13. 13. Hart, L., V. Krishnan, I. Adcock, P. Barnes, and K. Chung. 1998. Activation and localization of transcription factor, nuclear factor-kappaB, in asthma. Am. J. Respir. Crit. Care Med. 158:1585-1592.
14. 14. Lane, S. J., I. M. Adcock, D. Richards, C. Hawrylowicz, P. J. Barnes, and T. H. Lee. 1998. Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes. J. Clin. Invest. 102:2156-2164.
15. 15. Kelly, H. 1998. Establishing a therapeutic index for the inhaled corticosteroids. Part I: pharmacokinetic/pharmacodynamic comparison of the inhaled corticosteroids. J. Allergy Clin. Immunol 102:S36-S51.
16. 16. Barnes, N., C. Hallett, and T. Harris. 1998. Clinical experience with fluticasone propionate in asthma: a meta-analysis of efficacy and systemic activity compared with budesonide and beclomethasone dipropionate at half the microgram dose or less. Respir. Med. 92:95-104.
17. 17. Wieslander, E., E. Delander, L. Jarkelid, E. Hjertberg, A. Tunek, and R. Brattsand. 1998. Pharmacologic importance of the reversible fatty acid conjugation of budesonide studied in a rat cell line in vitro. Am. J. Respir. Cell Mol. Biol. 19:477-484.
18. 18. Kohout, T., J. O'Brian, S. Gaa, W. Lederer, and T. Rogers. 1996. Novel adenovirus component system that transfects cultured cardiac cells with high efficiency. Circ. Res. 78:971-977.
19. 19. Vayssiere, B., S. Dupont, A. Choquart, F. Petit, T. Garcia, C. Marchandeau, H. Gronemeyer, and M. Resche-Rigon. 1997. Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo. Mol. Endocrinol. 11:1245-1255.
20. 20. Kwon, O. J., P. J. Jose, R. A. Robbins, T. J. Schall, T. J. Williams, and P. J. Barnes. 1995. Glucocorticoid inhibition of RANTES expression in human lung epithelial cells. Am. J. Respir. Cell Mol. Biol. 12:488-496.
21. 21. Nelson, P., H. Kim, W. Manning, T. Goralski, and A. Krensky. 1993. Genomic organization and transcriptional regulation of the RANTES chemokine gene. J. Immunol. 151:2601-2612.
22. 22. Reichardt, H., K. Kaestner, J. Tuckermann, O. Kretz, O. Wessely, R. Bock, P. Gass, W. Schmid, P. Herrlich, P. Angel, and G. Schutz. 1998. DNA binding of the glucocorticoid receptor is not essential for survival. Cell 93:531-541.
23. 23. Pedersen, P., and P. O'Byrne. 1997. A comparison of the efficacy and safety of inhaled corticosteroids in asthma. Allergy 52:S1-S34.
24. 24. Derendorf, H., G. Hochhaus, B. Meibohm, H. Mollmann, and J. Barth. 1998. Pharmacokinetics and pharmacodynamics of inhaled corticosteroids. J. Allergy Clin. Immunol 101:S440-S446.
25. 25. van den Bosch, J. M. M., C. Westermann, J. Aumann, S. Edsbäcker, M. Tönnesson, and O. Selroos. 1993. Relationship between lung tissue and blood concentrations of inhaled budesonide. Biopharm. Drug Dispos. 14:455-459.
26. 26. Esmailpour, N., P. Hogger, K. Rabe, U. Heitmann, M. Nakashima, and P. Rohdewald. 1997. Distribution of inhaled fluticasone propionate between human lung tissue and serum in vivo. Eur. Respir. J. 10:1496-1499.
27. 27. Garbe, E., J. LeLorier, J. Boivin, and S. Suissa. 1997. Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma. J.A.M.A. 277:722-727.
28. 28. Macris, N. 1997. Glucocorticoid use and risks of ocular hypertension and glaucoma. J.A.M.A. 277:1929.
29. 29. Faul, J. L., W. Tormey, V. Tormey, and C. Burke. 1998. High dose inhaled corticosteroids and dose dependent loss of diabetic control. Br. Med. J.317:1491.
30. 30. Ray, K., S. Farrow, M. Daly, F. Talabot, and N. Searle. 1997. Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids. Biochem. J. 328:707-715.
31. 31. Högger, P., and P. Rohdewald. 1994. Binding kinetics of fluticasone propionate to the human glucocorticoid receptor. Steroids 59:597-602.
32. 32. Adcock, I. M., Y. Nasuhara, D. A. Stevens, and P. J. Barnes. 1999. Ligand-induced differentiation of glucocorticoid receptor (GR) transrepression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br. J. Pharmacol. 127:1003-1011.
33. 33. Edsbäcker, S., and S. Szefler. 1997. Glucocorticoid pharmacokinetics. In C. Lenfant, editor. Inhaled Glucocorticoids in Asthma. Marcel Dekker, New York. 381-445.
34. 34. Jeong, S., and A. Stein. 1994. Micrococcal nuclease digestion of nuclei reveals extended nucleosome ladders having anomalous DNA lengths for chromatin assembled on non-replicating plasmids in transfected cells. Nucleic Acids Res. 22:370-375.
35. 35. Walker, G., J. Pfeilschifter, and D. Kunz. 1997. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone: evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation. J. Biol. Chem. 272:16679-16687.