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Volumn 85, Issue 1, 2003, Pages 248-256

Peripherin-mediated death of motor neurons rescued by overexpression of neurofilament NF-H proteins

Author keywords

Amyotrophic lateral sclerosis; Cyclin dependant kinase 5; Intermediate filament; Neurofilaments; Peripherin; Transgenic

Indexed keywords

NEUROFILAMENT H PROTEIN; NEUROFILAMENT PROTEIN; PERIPHERIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

EID: 0037381242     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01653.x     Document Type: Article
Times cited : (46)

References (41)
  • 1
    • 0030698718 scopus 로고    scopus 로고
    • Heterodimeric associations between neuronal intermediate filament proteins
    • Athlan E. S. and Mushynski W. E. (1997) Heterodimeric associations between neuronal intermediate filament proteins. J. Biol. Chem. 272, 31073-31078.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31073-31078
    • Athlan, E.S.1    Mushynski, W.E.2
  • 2
    • 0033230327 scopus 로고    scopus 로고
    • Late onset death of motor neurons in mice overexpressing wild-type peripherin
    • Beaulieu J. M., Nguyen M. D. and Julien J. P. (1999a) Late onset death of motor neurons in mice overexpressing wild-type peripherin. J. Cell Biol. 147, 531-544.
    • (1999) J. Cell Biol. , vol.147 , pp. 531-544
    • Beaulieu, J.M.1    Nguyen, M.D.2    Julien, J.P.3
  • 3
    • 0032809052 scopus 로고    scopus 로고
    • Interactions between peripherin and neurofilaments in cultured cells, disruption of peripherin assembly by the NF-M and NF-H subunits
    • Beaulieu J. M., Robertson J. and Julien J. P. (1999b) Interactions between peripherin and neurofilaments in cultured cells, disruption of peripherin assembly by the NF-M and NF-H subunits. Biochem. Cell Biol. 77, 41-45.
    • (1999) Biochem. Cell Biol. , vol.77 , pp. 41-45
    • Beaulieu, J.M.1    Robertson, J.2    Julien, J.P.3
  • 4
    • 0034662120 scopus 로고    scopus 로고
    • Formation of intermediate filament protein aggreates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit
    • Beaulieu J. M., Jacomy H. and Julien J. P. (2000) Formation of intermediate filament protein aggreates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit. J. Neurosci. 20, 5321-5328.
    • (2000) J. Neurosci. , vol.20 , pp. 5321-5328
    • Beaulieu, J.M.1    Jacomy, H.2    Julien, J.P.3
  • 6
    • 0037175395 scopus 로고    scopus 로고
    • Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motor neuron disease
    • Bömmel H., Xie G., Rossoll W., Wiese S., Jablonka S., Boehm T. and Sendtner M. (2002) Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motor neuron disease. J. Cell Biol. 159, 563-569.
    • (2002) J. Cell Biol. , vol.159 , pp. 563-569
    • Bömmel, H.1    Xie, G.2    Rossoll, W.3    Wiese, S.4    Jablonka, S.5    Boehm, T.6    Sendtner, M.7
  • 7
    • 0014336826 scopus 로고
    • Proximal axonal enlargement in motor neuron disease
    • Carpenter S. (1968) Proximal axonal enlargement in motor neuron disease. Neurology 18, 841-851.
    • (1968) Neurology , vol.18 , pp. 841-851
    • Carpenter, S.1
  • 8
    • 0027220073 scopus 로고
    • Assembly of type IV neuronal intermediate filaments in non neuronal cells in the absence of preexisting cytoplasmic intermediate filaments
    • Ching G. Y. and Liem R. K. H. (1993) Assembly of type IV neuronal intermediate filaments in non neuronal cells in the absence of preexisting cytoplasmic intermediate filaments. J. Cell Biol. 122, 1323-3335.
    • (1993) J. Cell Biol. , vol.122 , pp. 1323-3335
    • Ching, G.Y.1    Liem, R.K.H.2
  • 9
    • 0033231494 scopus 로고    scopus 로고
    • From Charcot to SODI, mechanisms of selective motor neuron death in ALS
    • Cleveland D. W. (1999) From Charcot to SODI, mechanisms of selective motor neuron death in ALS. Neuron 24, 515-520.
    • (1999) Neuron , vol.24 , pp. 515-520
    • Cleveland, D.W.1
  • 10
    • 0026739393 scopus 로고
    • Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease
    • Corbo M. and Hays A. P. (1992) Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease. J. Neuropathol. Exp. Neurol. 51, 531-537.
    • (1992) J. Neuropathol. Exp. Neurol. , vol.51 , pp. 531-537
    • Corbo, M.1    Hays, A.P.2
  • 11
    • 0027465098 scopus 로고
    • Progressive neuropathy in transgenic mce expressing the human neurofilament heavy gene, a mouse model of amyotrophic lateral sclerosis
    • Côté F., Collard J. F. and Julien J. P. (1993) Progressive neuropathy in transgenic mce expressing the human neurofilament heavy gene, a mouse model of amyotrophic lateral sclerosis. Cell 73, 35-46.
    • (1993) Cell , vol.73 , pp. 35-46
    • Côté, F.1    Collard, J.F.2    Julien, J.P.3
  • 12
    • 0032483016 scopus 로고    scopus 로고
    • Protective effect of neurofilament NF-H overexpression in motor neuron disease induced by mutant superoxide dismutase
    • Couillard-Després J. S., Zhu Q., Wong P. C., Price D. L., Cleveland D. W. and Julien J. P. (1998) Protective effect of neurofilament NF-H overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc. Natl Acad. Sci. USA 95, 9626-9630.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9626-9630
    • Couillard-Després, J.S.1    Zhu, Q.2    Wong, P.C.3    Price, D.L.4    Cleveland, D.W.5    Julien, J.P.6
  • 13
    • 0030727581 scopus 로고    scopus 로고
    • The mechanisms of fast and slow transport in neurons: Identification and characterization of the new kinesin superfamily motors
    • Hirokawa N. (1997) The mechanisms of fast and slow transport in neurons: identification and characterization of the new kinesin superfamily motors. Curr. Opin. Neurobiol. 7, 605-614.
    • (1997) Curr. Opin. Neurobiol. , vol.7 , pp. 605-614
    • Hirokawa, N.1
  • 14
    • 0012632634 scopus 로고
    • The slow component of axonal transport
    • Hoffman P. N. and Lasek R. J. (1975) The slow component of axonal transport. J. Cell Biol. 642, 316-322.
    • (1975) J. Cell Biol. , vol.642 , pp. 316-322
    • Hoffman, P.N.1    Lasek, R.J.2
  • 15
    • 0033179415 scopus 로고    scopus 로고
    • Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration
    • Houseweart M. K. and Cleveland D. W. (1999) Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration. J. Neurosci. 19, 6446-6456.
    • (1999) J. Neurosci. , vol.19 , pp. 6446-6456
    • Houseweart, M.K.1    Cleveland, D.W.2
  • 16
    • 0035936804 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Unfolding toxicity misfolded
    • Julien J. P. (2001) Amyotrophic lateral sclerosis: unfolding toxicity misfolded. Cell 104, 581-591.
    • (2001) Cell , vol.104 , pp. 581-591
    • Julien, J.P.1
  • 17
    • 0034326239 scopus 로고    scopus 로고
    • Cytosqueletal abnormalities in amyotrophic lateral sclerosis, beneficial or detrimental effects?
    • Julien J. P. and Beaulieu J. M. (2000) Cytosqueletal abnormalities in amyotrophic lateral sclerosis, beneficial or detrimental effects? J. Neurol. Sci. 180, 7-14.
    • (2000) J. Neurol. Sci. , vol.180 , pp. 7-14
    • Julien, J.P.1    Beaulieu, J.M.2
  • 18
    • 0034576145 scopus 로고    scopus 로고
    • Electrophysiological properties of axons in mice lacking neurofilament subunit genes: Disparity between conduction velocity and axon diameter in absence of NF-H
    • Kriz J., Zhu Q., Julien J. P. and Padjen A. L. (2000) Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H. Brain Res. 885, 32-44.
    • (2000) Brain Res. , vol.885 , pp. 32-44
    • Kriz, J.1    Zhu, Q.2    Julien, J.P.3    Padjen, A.L.4
  • 19
    • 0027293898 scopus 로고
    • Neurofilaments are obligate heteropolymers in vivo
    • Lee M. K., Xu Z., Wong P. C. and Cleveland D. W. (1993) Neurofilaments are obligate heteropolymers in vivo. J. Cell. Biol. 122, 1337-1350.
    • (1993) J. Cell. Biol. , vol.122 , pp. 1337-1350
    • Lee, M.K.1    Xu, Z.2    Wong, P.C.3    Cleveland, D.W.4
  • 20
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death, implications for the pathogenesis of human motor neuron disease
    • Lee M. K., Marszalek J. R. and Cleveland D. W. (1994) A mutant neurofilament subunit causes massive, selective motor neuron death, implications for the pathogenesis of human motor neuron disease. Neuron 13, 975-988.
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 24
    • 0027478805 scopus 로고
    • Peripherin immunoreactive structures in amyotrophic lateral sclerosis
    • Migheli A., Pezzulo T., Attanasio A. and Schiffer D. (1993) Peripherin immunoreactive structures in amyotrophic lateral sclerosis. Lab. Inves. 68, 185-191.
    • (1993) Lab. Inves. , vol.68 , pp. 185-191
    • Migheli, A.1    Pezzulo, T.2    Attanasio, A.3    Schiffer, D.4
  • 25
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
    • Nguyen M. D., Larivière R. C. and Julien J. P. (2001) Deregulation of cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30, 135-147.
    • (2001) Neuron , vol.30 , pp. 135-147
    • Nguyen, M.D.1    Larivière, R.C.2    Julien, J.P.3
  • 26
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates cdk5 activity and promotes neurodegeneration
    • Patrick G. N., Zukerberg L., Nikolic M., de la Monte S., Dikkes P. and Tsai L. H. (1999) Conversion of p35 to p25 deregulates cdk5 activity and promotes neurodegeneration. Nature 402, 615-621.
    • (1999) Nature , vol.402 , pp. 615-621
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3    De la Monte, S.4    Dikkes, P.5    Tsai, L.H.6
  • 27
    • 0020412456 scopus 로고
    • A sequence of changes in cytoskeletal components during neuroblastoma differentiation
    • Portier M. M., Croizat B. and Gros F. (1982) A sequence of changes in cytoskeletal components during neuroblastoma differentiation. FEBS Lett. 146, 283-288.
    • (1982) FEBS Lett. , vol.146 , pp. 283-288
    • Portier, M.M.1    Croizat, B.2    Gros, F.3
  • 28
    • 0035889079 scopus 로고    scopus 로고
    • Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha
    • Robertson J., Beaulieu J. M., Doroudchi M. M., Durham H. D., Julien J. P. and Mushynski W. E. (2001) Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. J. Cell Biol. 155, 217-226.
    • (2001) J. Cell Biol. , vol.155 , pp. 217-226
    • Robertson, J.1    Beaulieu, J.M.2    Doroudchi, M.M.3    Durham, H.D.4    Julien, J.P.5    Mushynski, W.E.6
  • 30
    • 0034666282 scopus 로고    scopus 로고
    • Neurofilaments are transported rapidly but intermittently in axons: Implications for slow axonal transport
    • Roy S., Coffee P., Smith G., Liem R. K., Brady S. T. and Black M. M. (2000) Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport. J. Neurosci. 20, 6849-6861.
    • (2000) J. Neurosci. , vol.20 , pp. 6849-6861
    • Roy, S.1    Coffee, P.2    Smith, G.3    Liem, R.K.4    Brady, S.T.5    Black, M.M.6
  • 31
    • 0029812897 scopus 로고    scopus 로고
    • Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis
    • Sasaki S. and Iwata M. (1996) Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis. Neurology 47, 535-540.
    • (1996) Neurology , vol.47 , pp. 535-540
    • Sasaki, S.1    Iwata, M.2
  • 32
    • 0029778167 scopus 로고    scopus 로고
    • Visualization of slow axonal transport in vivo
    • Terada S., Nakata T., Peterson A. C. and Hirokawa N. (1996) Visualization of slow axonal transport in vivo. Science 273, 784-788.
    • (1996) Science , vol.273 , pp. 784-788
    • Terada, S.1    Nakata, T.2    Peterson, A.C.3    Hirokawa, N.4
  • 33
    • 0024305705 scopus 로고
    • Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein
    • Thompson M. A. and Ziff E. B. (1989) Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein. Neuron 2, 1043-1053.
    • (1989) Neuron , vol.2 , pp. 1043-1053
    • Thompson, M.A.1    Ziff, E.B.2
  • 34
    • 0025185388 scopus 로고
    • Regulation of peripherin and neurofilament expression in regenerating rat motor neurons
    • Troy C. M., Muma N. A., Greene L. A., Price D. L. and Shelanski M. L. (1990) Regulation of peripherin and neurofilament expression in regenerating rat motor neurons. Brain Res. 529, 232-238.
    • (1990) Brain Res. , vol.529 , pp. 232-238
    • Troy, C.M.1    Muma, N.A.2    Greene, L.A.3    Price, D.L.4    Shelanski, M.L.5
  • 35
    • 0033776708 scopus 로고    scopus 로고
    • Rapid movement of axonal neurofilaments interrupted by prolonged pauses
    • Wang L., Ho C. L., Sun D., Liem R. K. and Brown A. (2000) Rapid movement of axonal neurofilaments interrupted by prolonged pauses. Nat. Cell Biol. 2, 137-141.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 137-141
    • Wang, L.1    Ho, C.L.2    Sun, D.3    Liem, R.K.4    Brown, A.5
  • 36
    • 0033366384 scopus 로고    scopus 로고
    • Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
    • Williamson T. L. and Cleveland D. W. (1999) Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci. 2, 50-56.
    • (1999) Nat. Neurosci. , vol.2 , pp. 50-56
    • Williamson, T.L.1    Cleveland, D.W.2
  • 37
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W. and Price D. L. (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 38
    • 0033763630 scopus 로고    scopus 로고
    • Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis
    • Wong N. K., He B. P. and Strong M. J. (2000) Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 59, 972-982.
    • (2000) J. Neuropathol. Exp. Neurol. , vol.59 , pp. 972-982
    • Wong, N.K.1    He, B.P.2    Strong, M.J.3
  • 39
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • Zhang B., Tu P. H., Abtahian F., Trojanowski J. Q. and Lee V. M. Y. (1997) Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J. Cell Biol. 139, 1307-1315.
    • (1997) J. Cell Biol. , vol.139 , pp. 1307-1315
    • Zhang, B.1    Tu, P.H.2    Abtahian, F.3    Trojanowski, J.Q.4    Lee, V.M.Y.5
  • 41
    • 0031263931 scopus 로고    scopus 로고
    • Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments
    • Zhu Q., Couillard-Després J. S. and Julien J. P. (1997) Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Exp. Neurol. 148, 299-316.
    • (1997) Exp. Neurol. , vol.148 , pp. 299-316
    • Zhu, Q.1    Couillard-Després, J.S.2    Julien, J.P.3


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