Visualization of slow axonal transport in vivo

Science

Volumn 273, Issue 5276, 1996, Pages 784-788

  Terada, Sumio ^a   Nakata, Takao ^a   Peterson, Alan C ^b   Hirokawa, Nobutaka ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; NEUROFILAMENT PROTEIN; OLIGOMER; POLYMER;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; EXPRESSION VECTOR; MICROTUBULE; NERVE ENDING; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA; MUS MUSCULUS;

EID: 0029778167     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.273.5276.784     Document Type: Article

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50. We thank I. Saito and Y. Kanegae (Institute of Medical Science, University of Tokyo) and J. Miyazaki (University of Tokyo School of Medicine) for supplying us with their recombinant adenovirus vector system and the CAG promoter, respectively. Their technical advice was essential for the successful construction of our vector. We also thank Y. Komiya and T. Tashiro (Gunma University School of Medicinel for their technical assistance and advice on the microinjection into dorsal root ganglia in vivo; S. Ijuin (Nippon Bio-Rad Laboratories) for his technical assistance in confocal laser scanning microscopy; H. Yorifuji (National Defense Medical College) for his guidance in electron microscopic procedures; J.-P. Julien (Montreal General Hospital Research Institute, Centre for Research in Neuroscience, McGill University) and R. Nixon (McLean Hospital, Harvard Medical School) for helpful comments on the manuscript and useful discussions; Y. Kobayashi (Kyorin University School of Medicine) and T. Funakoshi, S. Kondo, Y. Okada, and other members of the Hirokawa lab for stimulating discussions and invaluable advice throughout; and Y. Kawasaki, H. Sato, H. Fukuda, and Y. Sugaya for their technical and secretarial assistance. Supported by a Special Grant-in-Aid for Scientific Research from the Japan Ministry of Educatton, Science and Culture; a grant from the Institute of Physical and Chemical Research (RIKEN) to N.H.; a Grant-in-Aid for Scientific Research from the Japan Ministry of Education, Science and Culture to S.T.; and grants from the Medical Research Council of Canada and Muscular Dystrophy Association of Canada to A.C.P.