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Volumn 13, Issue 2, 2003, Pages 161-169

Dosage compensation: An intertwined world of RNA and chromatin remodelling

Author keywords

[No Author keywords available]

Indexed keywords

RNA;

EID: 0037380140     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(03)00016-9     Document Type: Review
Times cited : (52)

References (59)
  • 1
    • 7144223296 scopus 로고
    • Gene action in the X-chromosome of the mouse (Mus musculus)
    • Lyon M. Gene action in the X-chromosome of the mouse (Mus musculus). Nature. 190:1961;372-373.
    • (1961) Nature , vol.190 , pp. 372-373
    • Lyon, M.1
  • 2
    • 0023057741 scopus 로고
    • Caenorhabditis elegans compensates for the difference in X chromosome dosage between the sexes by regulating transcript levels
    • Meyer B.J., Casson L.P. Caenorhabditis elegans compensates for the difference in X chromosome dosage between the sexes by regulating transcript levels. Cell. 47:1986;871-881.
    • (1986) Cell , vol.47 , pp. 871-881
    • Meyer, B.J.1    Casson, L.P.2
  • 3
    • 0013847439 scopus 로고
    • Synthesis of ribonuleic acid by the X-chromosomes of Drosophila melanogaster and the problem of dosage compensation
    • Mukherjee A.S., Beermann W. Synthesis of ribonuleic acid by the X-chromosomes of Drosophila melanogaster and the problem of dosage compensation. Nature. 207:1965;785-786.
    • (1965) Nature , vol.207 , pp. 785-786
    • Mukherjee, A.S.1    Beermann, W.2
  • 4
    • 0026566417 scopus 로고
    • Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei
    • Turner B.M., Birley A.J., Lavender J. Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell. 69:1992;375-384.
    • (1992) Cell , vol.69 , pp. 375-384
    • Turner, B.M.1    Birley, A.J.2    Lavender, J.3
  • 6
    • 0037022129 scopus 로고    scopus 로고
    • Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation
    • ••] were the first documenting that histone H3 lysine 9 methylation constitutes an early mark on the female inactive X chromosome.
    • ••] were the first documenting that histone H3 lysine 9 methylation constitutes an early mark on the female inactive X chromosome.
    • (2002) Curr. Biol. , vol.12 , pp. 247-251
    • Mermoud, J.E.1    Popova, B.2    Peters, A.H.3    Jenuwein, T.4    Brockdorff, N.5
  • 7
    • 0037150653 scopus 로고    scopus 로고
    • Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans
    • This study showed that in C. elegans eed1/enx1 homologues MES-6 and MES-2 also form a stable complex required for gene silencing and germline development, and this also correlates with histone H3 lysine 9 methylation.
    • Fong Y., Bender L., Wang W., Strome S. Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans. Science. 296:2002;2235-2238 This study showed that in C. elegans eed1/enx1 homologues MES-6 and MES-2 also form a stable complex required for gene silencing and germline development, and this also correlates with histone H3 lysine 9 methylation.
    • (2002) Science , vol.296 , pp. 2235-2238
    • Fong, Y.1    Bender, L.2    Wang, W.3    Strome, S.4
  • 8
    • 0018953342 scopus 로고
    • Control of X chromosome transcription by the maleless gene in Drosophila
    • Belote J.M., Lucchesi J.C. Control of X chromosome transcription by the maleless gene in Drosophila. Nature. 285:1980;573-575.
    • (1980) Nature , vol.285 , pp. 573-575
    • Belote, J.M.1    Lucchesi, J.C.2
  • 9
    • 0020360174 scopus 로고
    • Studies on the sex-specific lethals of Drosophila melanogaster. IV. Gynandromorph analysis of three male-specific lethals, mle, msl-2(27) and mle(3)132
    • Uenoyama T., Uchida S., Fukunaga A., Oishi K. Studies on the sex-specific lethals of Drosophila melanogaster. IV. Gynandromorph analysis of three male-specific lethals, mle, msl-2(27) and mle(3)132. Genetics. 102:1982;223-231.
    • (1982) Genetics , vol.102 , pp. 223-231
    • Uenoyama, T.1    Uchida, S.2    Fukunaga, A.3    Oishi, K.4
  • 10
    • 0028885520 scopus 로고
    • The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal
    • Bashaw G.J., Baker B.S. The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal. Development. 121:1995;3245-3258.
    • (1995) Development , vol.121 , pp. 3245-3258
    • Bashaw, G.J.1    Baker, B.S.2
  • 11
    • 0029063585 scopus 로고
    • Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila
    • Kelley R.L., Solovyeva I., Lyman L.M., Richman R., Solovyev V., Kuroda M.I. Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila. Cell. 81:1995;867-877.
    • (1995) Cell , vol.81 , pp. 867-877
    • Kelley, R.L.1    Solovyeva, I.2    Lyman, L.M.3    Richman, R.4    Solovyev, V.5    Kuroda, M.I.6
  • 12
    • 0029067981 scopus 로고
    • Male-specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex-specific regulation and encodes a protein with a RING finger and a metallothionein-like cysteine cluster
    • Zhou S., Yang Y., Scott M.J., Pannuti A., Fehr K.C., Eisen A., Koonin E.V., Fouts D.L., Wrightsman R., Manning J.E.et al. Male-specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex-specific regulation and encodes a protein with a RING finger and a metallothionein-like cysteine cluster. EMBO J. 14:1995;2884-2895.
    • (1995) EMBO J. , vol.14 , pp. 2884-2895
    • Zhou, S.1    Yang, Y.2    Scott, M.J.3    Pannuti, A.4    Fehr, K.C.5    Eisen, A.6    Koonin, E.V.7    Fouts, D.L.8    Wrightsman, R.9    Manning, J.E.10
  • 13
    • 0028926535 scopus 로고
    • Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila
    • Gorman M., Franke A., Baker B.S. Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila. Development. 121:1995;463-475.
    • (1995) Development , vol.121 , pp. 463-475
    • Gorman, M.1    Franke, A.2    Baker, B.S.3
  • 14
    • 0025944523 scopus 로고
    • The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila
    • Kuroda M.I., Kernan M.J., Kreber R., Ganetzky B., Baker B.S. The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila. Cell. 66:1991;935-947.
    • (1991) Cell , vol.66 , pp. 935-947
    • Kuroda, M.I.1    Kernan, M.J.2    Kreber, R.3    Ganetzky, B.4    Baker, B.S.5
  • 15
    • 0030891858 scopus 로고    scopus 로고
    • Mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila
    • Hilfiker A., Hilfiker-Kleiner D., Pannuti A., Lucchesi J.C. mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila. EMBO J. 16:1997;2054-2060.
    • (1997) EMBO J. , vol.16 , pp. 2054-2060
    • Hilfiker, A.1    Hilfiker-Kleiner, D.2    Pannuti, A.3    Lucchesi, J.C.4
  • 16
    • 0030975363 scopus 로고    scopus 로고
    • Genes expressed in neurons of adult male Drosophila
    • Amrein H., Axel R. Genes expressed in neurons of adult male Drosophila. Cell. 88:1997;459-469.
    • (1997) Cell , vol.88 , pp. 459-469
    • Amrein, H.1    Axel, R.2
  • 17
    • 0033166348 scopus 로고    scopus 로고
    • The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila
    • Franke A., Baker B.S. The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila. Mol. Cell. 4:1999;117-122.
    • (1999) Mol. Cell. , vol.4 , pp. 117-122
    • Franke, A.1    Baker, B.S.2
  • 18
    • 0342378132 scopus 로고    scopus 로고
    • RoX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system
    • Meller V.H., Wu K.H., Roman G., Kuroda M.I., Davis R.L. roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system. Cell. 88:1997;445-457.
    • (1997) Cell , vol.88 , pp. 445-457
    • Meller, V.H.1    Wu, K.H.2    Roman, G.3    Kuroda, M.I.4    Davis, R.L.5
  • 19
    • 0034729334 scopus 로고    scopus 로고
    • JIL-1, a chromosomal kinase implicated in regulation of chromatin structure, associated with the male specific lethal (MSL) Dosage Compensation Complex
    • Jin Y., Wang Y., Johansen J., Johansen K.M. JIL-1, a chromosomal kinase implicated in regulation of chromatin structure, associated with the male specific lethal (MSL) Dosage Compensation Complex. J. Cell. Biol. 149:2000;1005-1010.
    • (2000) J. Cell. Biol. , vol.149 , pp. 1005-1010
    • Jin, Y.1    Wang, Y.2    Johansen, J.3    Johansen, K.M.4
  • 20
    • 0028009294 scopus 로고
    • Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila
    • Bone J.R., Lavender J., Richman R., Palmer M.J., Turner B.M., Kuroda M.I. Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila. Genes Dev. 8:1994;96-104.
    • (1994) Genes Dev. , vol.8 , pp. 96-104
    • Bone, J.R.1    Lavender, J.2    Richman, R.3    Palmer, M.J.4    Turner, B.M.5    Kuroda, M.I.6
  • 21
    • 0033866836 scopus 로고    scopus 로고
    • Activation of transcription through histone H4 acetylation by MOF, an acetyl transferase essential for dosage compensation in Drosophila
    • Akhtar A., Becker P.B. Activation of transcription through histone H4 acetylation by MOF, an acetyl transferase essential for dosage compensation in Drosophila. Mol. Cell. 5:2000;367-375.
    • (2000) Mol. Cell. , vol.5 , pp. 367-375
    • Akhtar, A.1    Becker, P.B.2
  • 22
    • 0030218020 scopus 로고    scopus 로고
    • Dosage compensation and chromatin structure in Drosophila
    • Bashaw G.J., Baker B.S. Dosage compensation and chromatin structure in Drosophila. Curr. Opin. Genet. Dev. 6:1996;496-501.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 496-501
    • Bashaw, G.J.1    Baker, B.S.2
  • 23
    • 0033588309 scopus 로고    scopus 로고
    • Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin
    • Kelley R.L., Meller V.H., Gordadze P.R., Roman G., Davis R.L., Kuroda M.I. Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell. 98:1999;513-522.
    • (1999) Cell , vol.98 , pp. 513-522
    • Kelley, R.L.1    Meller, V.H.2    Gordadze, P.R.3    Roman, G.4    Davis, R.L.5    Kuroda, M.I.6
  • 24
    • 0034628634 scopus 로고    scopus 로고
    • Ordered assembly of roX RNAs into MSL complexes on the dosage- compensated X chromosome in Drosophila
    • Meller V.H., Gordadze P.R., Park Y., Chu X., Stuckenholz C., Kelley R.L., Kuroda M.I. Ordered assembly of roX RNAs into MSL complexes on the dosage- compensated X chromosome in Drosophila. Curr. Biol. 10:2000;136-143.
    • (2000) Curr. Biol. , vol.10 , pp. 136-143
    • Meller, V.H.1    Gordadze, P.R.2    Park, Y.3    Chu, X.4    Stuckenholz, C.5    Kelley, R.L.6    Kuroda, M.I.7
  • 25
    • 0035943734 scopus 로고    scopus 로고
    • Linking global histone acetylation to the transcription enhancement of X-chromosomal genes in Drosophila males
    • Using chromatin immunoprecipitation experiments it was demonstrated here that histone H4 acetylation on dosage compensated genes correlates with coding regions rather than the promoter regions on the X chromosome, implying that the DCC may function to promote transcription elongation.
    • Smith E.R., Allis C.D., Lucchesi J.C. Linking global histone acetylation to the transcription enhancement of X-chromosomal genes in Drosophila males. J. Biol. Chem. 276:2001;31483-31486 Using chromatin immunoprecipitation experiments it was demonstrated here that histone H4 acetylation on dosage compensated genes correlates with coding regions rather than the promoter regions on the X chromosome, implying that the DCC may function to promote transcription elongation.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31483-31486
    • Smith, E.R.1    Allis, C.D.2    Lucchesi, J.C.3
  • 26
    • 0035341311 scopus 로고    scopus 로고
    • Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site
    • The authors of this paper performed the first detailed characterisation of roX1 chromatin entry site and showed that a 217 bp region within roX1 is sufficient to attract dosage compensation proteins to an autosome.
    • Kageyama Y., Mengus G., Gilfillan G., Kennedy H.G., Stuckenholz C., Kelley R.L., Becker P.B., Kuroda M.I. Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site. EMBO J. 20:2001;2236-2245 The authors of this paper performed the first detailed characterisation of roX1 chromatin entry site and showed that a 217 bp region within roX1 is sufficient to attract dosage compensation proteins to an autosome.
    • (2001) EMBO J. , vol.20 , pp. 2236-2245
    • Kageyama, Y.1    Mengus, G.2    Gilfillan, G.3    Kennedy, H.G.4    Stuckenholz, C.5    Kelley, R.L.6    Becker, P.B.7    Kuroda, M.I.8
  • 27
    • 0030782516 scopus 로고    scopus 로고
    • Drosophila male-specific lethal-2 protein: Structure/function analysis and dependence on MSL-1 for chromosome association
    • Lyman L.M., Copps K., Rastelli L., Kelley R.L., Kuroda M.I. Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association. Genetics. 147:1997;1743-1753.
    • (1997) Genetics , vol.147 , pp. 1743-1753
    • Lyman, L.M.1    Copps, K.2    Rastelli, L.3    Kelley, R.L.4    Kuroda, M.I.5
  • 28
    • 0034597001 scopus 로고    scopus 로고
    • Targeting the chromatin-remodelling MSL complex of Drosophila to its sites of action on the X chromosome requires both acetyl transferase and ATPase activities
    • Gu W., Wei X., Pannuti A., Lucchesi J.C. Targeting the chromatin-remodelling MSL complex of Drosophila to its sites of action on the X chromosome requires both acetyl transferase and ATPase activities. EMBO J. 19:2000;5202-5211.
    • (2000) EMBO J. , vol.19 , pp. 5202-5211
    • Gu, W.1    Wei, X.2    Pannuti, A.3    Lucchesi, J.C.4
  • 29
    • 0030089613 scopus 로고    scopus 로고
    • RNA-dependent association of the Drosophila maleless protein with the male X chromosome
    • Richter L., Bone J.R., Kuroda M.I. RNA-dependent association of the Drosophila maleless protein with the male X chromosome. Genes Cells. 1:1996;325-336.
    • (1996) Genes Cells , vol.1 , pp. 325-336
    • Richter, L.1    Bone, J.R.2    Kuroda, M.I.3
  • 30
    • 0034699391 scopus 로고    scopus 로고
    • Chromodomains as RNA interaction modules
    • We showed here that the MOF HAT is tethered to the male X chromosome by RNA and that histone acetylation on the X chromosome has a high turnover. We also presented evidence that chromodomains of MOF and MSL-3 interact with RNA.
    • Akhtar A., Zink D., Becker P.B. Chromodomains as RNA interaction modules. Nature. 407:2000;405-409 We showed here that the MOF HAT is tethered to the male X chromosome by RNA and that histone acetylation on the X chromosome has a high turnover. We also presented evidence that chromodomains of MOF and MSL-3 interact with RNA.
    • (2000) Nature , vol.407 , pp. 405-409
    • Akhtar, A.1    Zink, D.2    Becker, P.B.3
  • 31
    • 0036500632 scopus 로고    scopus 로고
    • The roX genes encode redundant male-specific lethal transcripts required for targeting of the MSL complex
    • Even though roX RNAs seem to have redundant function, it is convincingly shown here that deletion of roX1 and roX2 genes in flies causes male-specific lethality and mistargeting of the MSL proteins as well as histone H4 lysine 16 acetylation.
    • Meller V., Rattner B.P. The roX genes encode redundant male-specific lethal transcripts required for targeting of the MSL complex. EMBO J. 21:2002;1084-1091 Even though roX RNAs seem to have redundant function, it is convincingly shown here that deletion of roX1 and roX2 genes in flies causes male-specific lethality and mistargeting of the MSL proteins as well as histone H4 lysine 16 acetylation.
    • (2002) EMBO J. , vol.21 , pp. 1084-1091
    • Meller, V.1    Rattner, B.P.2
  • 32
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • Volpe T.A., Kidner C., Hall I.M., Teng G., Grewal S.I.S., Martienssen R.A. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science. 297:2002;1833-1837.
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.S.5    Martienssen, R.A.6
  • 33
    • 0036775704 scopus 로고    scopus 로고
    • Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α
    • Muchardt C., Guilleme M., Seeler J.S., Trouche D., Dejean A., Yaniv M. Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α EMBO Rep. 3:2002;975-981.
    • (2002) EMBO Rep. , vol.3 , pp. 975-981
    • Muchardt, C.1    Guilleme, M.2    Seeler, J.S.3    Trouche, D.4    Dejean, A.5    Yaniv, M.6
  • 34
    • 0036509836 scopus 로고    scopus 로고
    • Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component
    • Maison C., Bailly D., Peter A.H.F.M., Quivy J.P., Roche D., Taddei A., Lachner M., Jenuwein T., Almouzni G. Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component. Nat. Genet. 30:2002;329-334.
    • (2002) Nat. Genet. , vol.30 , pp. 329-334
    • Maison, C.1    Bailly, D.2    Peter, A.H.F.M.3    Quivy, J.P.4    Roche, D.5    Taddei, A.6    Lachner, M.7    Jenuwein, T.8    Almouzni, G.9
  • 35
    • 0037154963 scopus 로고    scopus 로고
    • Cooperation between complexes that regulate chromatin structure and transcription
    • Narlikar G.J., Fan H.Y., Kingston R.E. Cooperation between complexes that regulate chromatin structure and transcription. Cell. 108:2002;475-487.
    • (2002) Cell , vol.108 , pp. 475-487
    • Narlikar, G.J.1    Fan, H.Y.2    Kingston, R.E.3
  • 36
    • 0034902187 scopus 로고    scopus 로고
    • Nucleosome mobilization and positioning by ISWI-containing chromatin-remodeling factors
    • Langst G., Becker P.B. Nucleosome mobilization and positioning by ISWI-containing chromatin-remodeling factors. J. Cell. Sci. 114:2001;2561-2568.
    • (2001) J. Cell. Sci. , vol.114 , pp. 2561-2568
    • Langst, G.1    Becker, P.B.2
  • 38
    • 0036208153 scopus 로고    scopus 로고
    • Modulation of ISWI function by site-specific histone acetylation
    • Here, genetics and biochemistry are nicely combined to show that ISWI and histone H4 acetylation on the X chromosome counteract each other. ISWI-lacking mutants have altered chromatin structure, which can be rescued by lowering acetylation levels on the X chromosome.
    • Corona D.F., Clapier C., Becker P.B., Tamkun J.W. Modulation of ISWI function by site-specific histone acetylation. EMBO Rep. 3:2002;242-247 Here, genetics and biochemistry are nicely combined to show that ISWI and histone H4 acetylation on the X chromosome counteract each other. ISWI-lacking mutants have altered chromatin structure, which can be rescued by lowering acetylation levels on the X chromosome.
    • (2002) EMBO Rep. , vol.3 , pp. 242-247
    • Corona, D.F.1    Clapier, C.2    Becker, P.B.3    Tamkun, J.W.4
  • 39
    • 0035097883 scopus 로고    scopus 로고
    • The histone H4 acetyl transferase MOF uses a C2HC zinc finger for substrate recognition
    • We here characterised MOF substrate specificity and showed that the MOF zinc finger region is important for interaction with histone H4 tail on a nucleosomal substrate.
    • Akhtar A., Becker P.B. The histone H4 acetyl transferase MOF uses a C2HC zinc finger for substrate recognition. EMBO Rep. 2:2001;113-118 We here characterised MOF substrate specificity and showed that the MOF zinc finger region is important for interaction with histone H4 tail on a nucleosomal substrate.
    • (2001) EMBO Rep. , vol.2 , pp. 113-118
    • Akhtar, A.1    Becker, P.B.2
  • 40
    • 0034721670 scopus 로고    scopus 로고
    • The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
    • Goldmark J.P., Fazzio T.G., Estep P.W., Church G.M., Tsukiyama T. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell. 103:2000;423-433.
    • (2000) Cell , vol.103 , pp. 423-433
    • Goldmark, J.P.1    Fazzio, T.G.2    Estep, P.W.3    Church, G.M.4    Tsukiyama, T.5
  • 41
    • 0034817393 scopus 로고    scopus 로고
    • Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression
    • Fazzio T.G., Kooperberg C., Goldmark J.P., Neal C., Basom R., Delrow J., Tsukiyama T. Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression. Mol. Cell. Biol. 21:2001;6450-6460.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6450-6460
    • Fazzio, T.G.1    Kooperberg, C.2    Goldmark, J.P.3    Neal, C.4    Basom, R.5    Delrow, J.6    Tsukiyama, T.7
  • 42
    • 0028297161 scopus 로고
    • Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster
    • Hiebert J.C., Birchler J.A. Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster. Genetics. 136:1994;913-926.
    • (1994) Genetics , vol.136 , pp. 913-926
    • Hiebert, J.C.1    Birchler, J.A.2
  • 43
    • 0035875867 scopus 로고    scopus 로고
    • Dosage-dependent gene regulation in multicellular eukaryotes: Implications for dosage compensation, aneuploid syndromes, and quantitative traits
    • Birchler J.A., Bhadra U., Bhadra M.P., Auger D.L. Dosage-dependent gene regulation in multicellular eukaryotes: implications for dosage compensation, aneuploid syndromes, and quantitative traits. Dev. Biol. 234:2001;275-288.
    • (2001) Dev. Biol. , vol.234 , pp. 275-288
    • Birchler, J.A.1    Bhadra, U.2    Bhadra, M.P.3    Auger, D.L.4
  • 44
    • 0033166349 scopus 로고    scopus 로고
    • JIL1: A novel chromosomal tandem kinase implicated in transcriptional regulation in Drosophila
    • Jin Y., Wang Y., Walker D.L., Dong H., Conley C., Johansen J., Johansen K.M. JIL1: A novel chromosomal tandem kinase implicated in transcriptional regulation in Drosophila. Mol. Cell. 4:1999;129-135.
    • (1999) Mol. Cell. , vol.4 , pp. 129-135
    • Jin, Y.1    Wang, Y.2    Walker, D.L.3    Dong, H.4    Conley, C.5    Johansen, J.6    Johansen, K.M.7
  • 45
    • 0035906859 scopus 로고    scopus 로고
    • The Jil-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila
    • Here, hypomorphic mutant alleles of JIL-1 the histone H3 kinase were created to show that JIL-1 is required for global chromatin structure. The X chromosome was show to be severely affected. However, despite the altered appearance the dosage compensation members were still found on the male X chromosome.
    • Wang Y., Zhang W., Jin Y., Johansen J., Johansen K.M. The Jil-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila. Cell. 105:2001;433-443 Here, hypomorphic mutant alleles of JIL-1 the histone H3 kinase were created to show that JIL-1 is required for global chromatin structure. The X chromosome was show to be severely affected. However, despite the altered appearance the dosage compensation members were still found on the male X chromosome.
    • (2001) Cell , vol.105 , pp. 433-443
    • Wang, Y.1    Zhang, W.2    Jin, Y.3    Johansen, J.4    Johansen, K.M.5
  • 46
    • 0035943606 scopus 로고    scopus 로고
    • Recruitment of the male-specific lethal (MSL) dosage compensation complex to an autosomally integrated roX chromatin entry site correlates with an increased expression of an adjacent reporter gene in male Drosophila
    • ••] was not sufficient for twofold transcription increase, suggesting that additional sequences may be required for transcription regulation.
    • ••] was not sufficient for twofold transcription increase, suggesting that additional sequences may be required for transcription regulation.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31953-31958
    • Henry, R.A.1    Tews, B.2    Li, X.3    Scott, M.J.4
  • 47
    • 0036479009 scopus 로고    scopus 로고
    • Chromosomal silencing and localisation are mediated by different domains of Xist RNA
    • In this study, the authors made a series of deletions of Xist RNA and by using an elegant inducible ES cell expression system showed that different functional domains can be identified in Xist RNA. A silencing feature within Xist seems to reside within a conserved repeat sequence at the 5′ end of the RNA.
    • Wutz A., Rasmussen T.P., Jaenisch R. Chromosomal silencing and localisation are mediated by different domains of Xist RNA. Nat. Genet. 30:2002;1-8 In this study, the authors made a series of deletions of Xist RNA and by using an elegant inducible ES cell expression system showed that different functional domains can be identified in Xist RNA. A silencing feature within Xist seems to reside within a conserved repeat sequence at the 5′ end of the RNA.
    • (2002) Nat. Genet. , vol.30 , pp. 1-8
    • Wutz, A.1    Rasmussen, T.P.2    Jaenisch, R.3
  • 48
    • 0036532224 scopus 로고    scopus 로고
    • X-chromosome inactivation and the search for chromosome-wide silencers
    • Cohen D.E., Lee J.T. X-chromosome inactivation and the search for chromosome-wide silencers. Curr. Opin. Genet. Dev. 12:2002;219-224.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 219-224
    • Cohen, D.E.1    Lee, J.T.2
  • 49
    • 0035228079 scopus 로고    scopus 로고
    • X-chromosome inactivation: Counting, choice and initiation
    • Avner P., Heard E. X-chromosome inactivation: counting, choice and initiation. Nat. Rev. Genet. 2:2001;59-67.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 59-67
    • Avner, P.1    Heard, E.2
  • 50
    • 0036641071 scopus 로고    scopus 로고
    • X-chromosome inactivation: Closing in on proteins that bind Xist RNA
    • Brockdorff N. X-chromosome inactivation: closing in on proteins that bind Xist RNA. Trends Genet. 18:2002;352-358.
    • (2002) Trends Genet. , vol.18 , pp. 352-358
    • Brockdorff, N.1
  • 53
    • 0037166937 scopus 로고    scopus 로고
    • Cell cycle-dependent localisation of macro H2A in chromatin of the inactive X chromosome
    • Chadwick B.P., Willard H.F. Cell cycle-dependent localisation of macro H2A in chromatin of the inactive X chromosome. J. Cell. Biol. 157:2002;1113-1123.
    • (2002) J. Cell. Biol. , vol.157 , pp. 1113-1123
    • Chadwick, B.P.1    Willard, H.F.2
  • 54
    • 18744372123 scopus 로고    scopus 로고
    • BRCA1 supports XIST RNA concentration on the inactive X chromosome
    • An interesting new connection between the well-studied BRCA1 gene and X inactivation is made in this paper. Using a combination of knockout cell lines as well as RNA interference, BRCA1 is shown to play an important role in Xist RNA localisation, therefore leading to new insights into X inactivation.
    • Ganesan S., Silver D.P., Greenberg R.A., Avni D., Drapkin R., Miron A., Mok S.C., Randrianarison V., Brodie S., Salstrom S.et al. BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell. 111:2002;393-405 An interesting new connection between the well-studied BRCA1 gene and X inactivation is made in this paper. Using a combination of knockout cell lines as well as RNA interference, BRCA1 is shown to play an important role in Xist RNA localisation, therefore leading to new insights into X inactivation.
    • (2002) Cell , vol.111 , pp. 393-405
    • Ganesan, S.1    Silver, D.P.2    Greenberg, R.A.3    Avni, D.4    Drapkin, R.5    Miron, A.6    Mok, S.C.7    Randrianarison, V.8    Brodie, S.9    Salstrom, S.10
  • 55
    • 0033973262 scopus 로고    scopus 로고
    • A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF
    • Neal K.C., Pannuti A., Smith E.R., Lucchesi J.C. A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. Biochim. Biophys. Acta. 1490:2000;170-174.
    • (2000) Biochim. Biophys. Acta , vol.1490 , pp. 170-174
    • Neal, K.C.1    Pannuti, A.2    Smith, E.R.3    Lucchesi, J.C.4
  • 56
    • 0033868471 scopus 로고    scopus 로고
    • Origin and evolution of the regulatory gene male-specific lethal-3
    • Marin I., Baker B.S. Origin and evolution of the regulatory gene male-specific lethal-3. Mol. Biol. Evol. 17:2000;1240-1250.
    • (2000) Mol. Biol. Evol. , vol.17 , pp. 1240-1250
    • Marin, I.1    Baker, B.S.2
  • 57
    • 0034602829 scopus 로고    scopus 로고
    • MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila
    • Scott M.J., Pan L.L., Cleland S.B., Knox A.L., Heinrich J. MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila. EMBO J. 19:2000;144-155.
    • (2000) EMBO J. , vol.19 , pp. 144-155
    • Scott, M.J.1    Pan, L.L.2    Cleland, S.B.3    Knox, A.L.4    Heinrich, J.5
  • 58
    • 0027232086 scopus 로고
    • The male-specific lethal-one (msl-1) gene of Drosophila melanogaster encodes a novel protein that associates with the X chromosome in males
    • Palmer M.J., Mergner V.A., Richman R., Manning J.E., Kuroda M.I., Lucchesi J.C. The male-specific lethal-one (msl-1) gene of Drosophila melanogaster encodes a novel protein that associates with the X chromosome in males. Genetics. 134:1993;545-557.
    • (1993) Genetics , vol.134 , pp. 545-557
    • Palmer, M.J.1    Mergner, V.A.2    Richman, R.3    Manning, J.E.4    Kuroda, M.I.5    Lucchesi, J.C.6
  • 59
    • 0033988212 scopus 로고    scopus 로고
    • The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation
    • Smith E.R., Pannuti A., Gu W., Steurnagel A., Cook R.G., Allis C.D., Lucchesi J.C. The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation. Mol. Cell. Biol. 20:2000;312-318.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 312-318
    • Smith, E.R.1    Pannuti, A.2    Gu, W.3    Steurnagel, A.4    Cook, R.G.5    Allis, C.D.6    Lucchesi, J.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.