Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation

Current Biology

Volumn 12, Issue 3, 2002, Pages 247-251

  Mermoud, Jacqueline E ^a   Popova, Bilyana ^a   Peters, Antoine H F M ^b   Jenuwein, Thomas ^b   Brockdorff, Neil ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; LYSINE;

ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; METAPHASE; METHYLATION; STEM CELL; TIME; X CHROMOSOME; Y CHROMOSOME;

CELL DIFFERENTIATION; DOSAGE COMPENSATION, GENETIC; FEMALE; GENE SILENCING; HISTONES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYSINE; METAPHASE; METHYLATION; MICROSCOPY, FLUORESCENCE; STEM CELLS; TIME FACTORS; X CHROMOSOME; Y CHROMOSOME;

MAMMALIA;

EID: 0037022129     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00660-7     Document Type: Article

References (30)

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3. Differentiation of the X chromosome in early female mouse embryos
4. Reactivation of an inactive X chromosome: Evidence for X-inactivation by DNA methylation
5. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene-expression
6. Differential underacetylation of histones H2A, H3 and H4 on the inactive X chromosome in human female cells
7. Reduced levels of histone H3 acetylation on the inactive X chromosome in human females
8. Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals
9. Histone H2A variants and the inactive X chromosome: Identification of a second macroH2A variant
10. MacroH2A2, a new member of the macroH2A core histone family
11. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
12. The human XIST gene: Analysis of a 17kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
13. The product of the mouse Xist gene is a 15kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
14. Requirement for Xist in X chromosome inactivation
15. A 450 kb transgene displays properties of the mammalian X inactivation center
16. XIST RNA paints the inactive X chromosome at interphase: Evidence for a novel RNA involved in nuclear chromosome structure
17. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
18. Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation
19. X-inactivation and histone H4 acetylation in embryonic stem cells
20. Stabilisation of Xist RNA mediates initiation of X chromosome inactivation
21. Histone macroH2A1.2 relocates to the inactive X chromosome after initiation and propagation of X inactivation
22. Histone H3 Lysine 9 methylation is an epigenetic imprint for facultative heterochromatin at the inactive X chromosome
23. Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes
24. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
25. Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries
26. Correlation between histone lysine methylation and developmental changes at the chicken β-globin locus
27. Re-SET-ting heterochromatin by histone methyltransferases
28. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
29. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromodomain
30. Regulation of chromatin structure by site-specific histone H3 methyltransferases