-
1
-
-
0036136424
-
Leukocyte adhesion deficiency syndromes: Adhesion and tethering defects involving beta 2 integrins and selectin ligands
-
Bunting M, Harris ES, McIntyre TM, et al.: Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. Curr Opin Hematol 2002, 9:30-35. • The authors review the molecular basis for LAD syndromes and the critical importance of defective leukocyte interactions with inflamed endothelium.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 30-35
-
-
Bunting, M.1
Harris, E.S.2
McIntyre, T.M.3
-
2
-
-
0013324769
-
Neutrophil degranulation: Mechanisms of regulation and dysregulation in interactions with endothelial cells
-
Edited by Weir EK, Reeve HL, Reeves JT. New York: Futura Publishing Co.
-
Imaizumi T, Topham MK, McIntyre T, et al.: Neutrophil degranulation: mechanisms of regulation and dysregulation in interactions with endothelial cells. In Interactions of Blood and the Pulmonary Circulation. Edited by Weir EK, Reeve HL, Reeves JT. New York: Futura Publishing Co.; 2002:239-254.
-
(2002)
Interactions of Blood and the Pulmonary Circulation
, pp. 239-254
-
-
Imaizumi, T.1
Topham, M.K.2
McIntyre, T.3
-
3
-
-
0035853111
-
Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
-
Borsig L, Wong R, Feramisco J, et al.: Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci U S A 2001, 98:3352-3357.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3352-3357
-
-
Borsig, L.1
Wong, R.2
Feramisco, J.3
-
4
-
-
0034880545
-
Leukocyte recruitment at sites of tumor: Dissonant orchestration
-
Carlos TM: Leukocyte recruitment at sites of tumor: dissonant orchestration. J Leukoc Biol 2001, 70:171-184. • Mechanisms of regulated and dysregulated leukocyte accumulation in tumors are discussed in this review. Responses to immunotherapeutic regimens against some solid tumors may depend on orchestrated leukocyte recruitment.
-
(2001)
J Leukoc Biol
, vol.70
, pp. 171-184
-
-
Carlos, T.M.1
-
5
-
-
0037133173
-
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis
-
Borsig L, Wong R, Hynes RO, et al.: Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis. Proc Natl Acad Sci U S A 2002, 99:2193-2198. •• L-selectin on leukocytes and P-selectin on platelets act at different points to facilitate metastasis of bloodborne tumor cells in murine models. Also see [3,4*].
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2193-2198
-
-
Borsig, L.1
Wong, R.2
Hynes, R.O.3
-
6
-
-
0037022684
-
Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm
-
Turhan A, Weiss LA, Mohandas N, et al.: Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A 2002, 99:3047-3051. •• Binding of sickled erythrocytes to adherent leukocytes was critical in a murine model of sickle cell anemia vasculopathy. Mice deficient in P-selectin and Eselectin were protected from formation of heterotypic aggregates consisting of sickled red blood cells and leukocytes and from vascular occlusion, suggesting that signaling mediated by engagement of selectin ligands enhances binding of leukocytes to circulating erythrocytes. Also see [7].
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3047-3051
-
-
Turhan, A.1
Weiss, L.A.2
Mohandas, N.3
-
7
-
-
0036177721
-
Sickle cell vaso-occlusion: Multistep and multicellular paradigm
-
Frenette PS: Sickle cell vaso-occlusion: multistep and multicellular paradigm. Curr Opin Hematol 2002, 9:101-106.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 101-106
-
-
Frenette, P.S.1
-
8
-
-
0034609968
-
T-cell function and migration: Two sides of the same coin
-
von Andrian UH, Mackay CR: T-cell function and migration: two sides of the same coin. N Engl J Med 2000, 343:1020-1034.
-
(2000)
N Engl J Med
, vol.343
, pp. 1020-1034
-
-
Von Andrian, U.H.1
Mackay, C.R.2
-
9
-
-
0036024089
-
Chemokines in rapid leukocyte adhesion triggering and migration
-
Johnston B, Butcher EC: Chemokines in rapid leukocyte adhesion triggering and migration. Semin Immunol 2002, 14:83-92. •• A review of chemokine signaling focused on lymphocyte-endothelial interactions from a group that has made major contributions to the field.
-
(2002)
Semin Immunol
, vol.14
, pp. 83-92
-
-
Johnston, B.1
Butcher, E.C.2
-
10
-
-
0037103165
-
Lipopolysaccharide-induced leukocyteendothelial cell interactions: A role for CD14 versus toll-like receptor 4 within microvessels
-
Andonegui G, Coyed SM, Kubes P: Lipopolysaccharide-induced leukocyteendothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. J Immunol 2002, 169:2111-2119. •• This study systematically examined leukocyte-endothelial interactions in wild-type animals and mice deficient in TLR4 and CD14 and found organ-specific variations in P-selectin expression and leukocyte recruitment that varied in animals challenged with lipopolysaccharide locally or systemically. Also see [22]. It should be kept in mind that lipopolysaccharide directly induces P-selectin expression in murine, but not human, endothelial cells.
-
(2002)
J Immunol
, vol.169
, pp. 2111-2119
-
-
Andonegui, G.1
Coyed, S.M.2
Kubes, P.3
-
11
-
-
0037155342
-
Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium
-
Bowden RA, Ding ZM, Donnachie EM, et al.: Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium. Circ Res 2002, 90:562-569.
-
(2002)
Circ Res
, vol.90
, pp. 562-569
-
-
Bowden, R.A.1
Ding, Z.M.2
Donnachie, E.M.3
-
12
-
-
0036721627
-
Subset-specific reductions in lung lymphocyte accumulation following intratracheal antigen challenge in endothelial selectin-deficient mice
-
Curtis JL, Sonstein J, Craig RA, et al.: Subset-specific reductions in lung lymphocyte accumulation following intratracheal antigen challenge in endothelial selectin-deficient mice. J Immunol 2002, 169:2570-2579.
-
(2002)
J Immunol
, vol.169
, pp. 2570-2579
-
-
Curtis, J.L.1
Sonstein, J.2
Craig, R.A.3
-
13
-
-
0036677433
-
Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally
-
Hidalgo A, Weiss LA, Frenette PS: Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally. J Clin Invest 2002, 110:559-569.
-
(2002)
J Clin Invest
, vol.110
, pp. 559-569
-
-
Hidalgo, A.1
Weiss, L.A.2
Frenette, P.S.3
-
14
-
-
0037100456
-
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis
-
Kerfoot SM, Kubes P: Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J Immunol 2002, 169:1000-1006.
-
(2002)
J Immunol
, vol.169
, pp. 1000-1006
-
-
Kerfoot, S.M.1
Kubes, P.2
-
15
-
-
0037083641
-
Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: Critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors
-
Piccio L, Rossi B, Scarpini E, et al.: Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors. J Immunol 2002, 168:1940-1949.
-
(2002)
J Immunol
, vol.168
, pp. 1940-1949
-
-
Piccio, L.1
Rossi, B.2
Scarpini, E.3
-
16
-
-
0034846702
-
Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation
-
McEver RP: Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost 2001, 86:746-756. • A comprehensive review that contains detailed information on PSGL-1 structure and function and examines platelet interactions with the vascular wall in addition to the molecular basis for leukocyte-endothelial interactions. Also see [24**,31**,33.**].
-
(2001)
Thromb Haemost
, vol.86
, pp. 746-756
-
-
McEver, R.P.1
-
17
-
-
0035479822
-
Leukocyte transendothelial migration: Orchestrating the underlying molecular machinery
-
Worthylake RA, Burridge K: Leukocyte transendothelial migration: orchestrating the underlying molecular machinery. Curr Opin Cell Biol 2001, 13:569-577. • This review focuses on leukocyte transmigration in addition to molecular aspects of other critical events in the multistep paradigm.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 569-577
-
-
Worthylake, R.A.1
Burridge, K.2
-
18
-
-
0034952240
-
Pathways and bottlenecks in the web of inflammatory adhesion molecules and chemoattractants
-
Ley K: Pathways and bottlenecks in the web of inflammatory adhesion molecules and chemoattractants. Immunol Res 2001, 24:87-95. • A thoughtful analysis of inflammatory checkpoints and pathways that draws on extensive studies using genetically altered mice. Adhesion and signaling in leukocyte-endothelial interactions are interactive at the molecular level rather than absolutely linear and stepwise, and may be grouped into preferential pathways depending on the inflammatory process.
-
(2001)
Immunol Res
, vol.24
, pp. 87-95
-
-
Ley, K.1
-
19
-
-
0030587922
-
Adhesion and signaling in vascular cell-cell interactions
-
Zimmerman GA, McIntyre TM, Prescott SM: Adhesion and signaling in vascular cell-cell interactions. J Clin Invest 1996, 98:1699-1702.
-
(1996)
J Clin Invest
, vol.98
, pp. 1699-1702
-
-
Zimmerman, G.A.1
McIntyre, T.M.2
Prescott, S.M.3
-
20
-
-
0036134963
-
Toll-like receptors: How they work and what they do
-
Beufler B: Toll-like receptors: how they work and what they do. Curr Opin Hematol 2002, 9:2-10.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 2-10
-
-
Beufler, B.1
-
21
-
-
0035500915
-
Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells
-
Neilsen PO, Zimmerman GA, McIntyre TM: Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells. J Immunol 2001, 167:5231-5239. • Bacterial lipoproteins trigger endothelial cell-dependent neutrophil adhesion and expression of adhesion molecules and chemokines when examined by expression array analysis, as does lipopolysaccharide.
-
(2001)
J Immunol
, vol.167
, pp. 5231-5239
-
-
Neilsen, P.O.1
Zimmerman, G.A.2
McIntyre, T.M.3
-
22
-
-
0036569445
-
Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid
-
Yipp BG, Andonegui G, Howlett CJ, et al.: Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid. J Immunol 2002, 168:4650-4658.
-
(2002)
J Immunol
, vol.168
, pp. 4650-4658
-
-
Yipp, B.G.1
Andonegui, G.2
Howlett, C.J.3
-
23
-
-
0035833529
-
Dysfunction of endothelial protein C activation in severe meningococcal sepsis
-
Faust SN, Levin M, Harrison OB, et al.: Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med 2001, 345:408-416.
-
(2001)
N Engl J Med
, vol.345
, pp. 408-416
-
-
Faust, S.N.1
Levin, M.2
Harrison, O.B.3
-
24
-
-
0035964311
-
Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow
-
Ramachandran V, Yago T, Epperson TK, et al.: Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow. Proc Natl Acad Sci U S A 2001, 98:10166-10171. •• The authors used dimeric and monomeric forms of P-selectin and PSGL-1 to show that dimerization of selectins and selectin ligands strengthens tethers of rolling leukocytes.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10166-10171
-
-
Ramachandran, V.1
Yago, T.2
Epperson, T.K.3
-
25
-
-
0035494494
-
Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether
-
Dwir O, Kansas GS, Alon R: Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether. J Cell Biol 2001, 155:145-156. •• Intracellular anchorage of L-selectin strengthened rolling of transfected cells in an analysis using truncations of the cytoplasmic domain. Under some conditions, L-selectin dimerization enhances tether formation, as does dimerization of selectin ligands. See also [26,27].
-
(2001)
J Cell Biol
, vol.155
, pp. 145-156
-
-
Dwir, O.1
Kansas, G.S.2
Alon, R.3
-
26
-
-
0037077193
-
L-selectin dimerization enhances tether formation to properly spaced ligand
-
Dwir O, Steeber DA, Schwarz US, et al.: L-selectin dimerization enhances tether formation to properly spaced ligand. J Biol Chem 2002, 277:21130-21139.
-
(2002)
J Biol Chem
, vol.277
, pp. 21130-21139
-
-
Dwir, O.1
Steeber, D.A.2
Schwarz, U.S.3
-
27
-
-
0037097835
-
Attachment of the PSGL-1 cytoplasmic domain to the actin cytoskeleton is essential for leukocyte rolling on P-selectin
-
Snapp KR, Heitzig CE, Kansas GS: Attachment of the PSGL-1 cytoplasmic domain to the actin cytoskeleton is essential for leukocyte rolling on P-selectin. Blood 2002, 99:4494-4502.
-
(2002)
Blood
, vol.99
, pp. 4494-4502
-
-
Snapp, K.R.1
Heitzig, C.E.2
Kansas, G.S.3
-
28
-
-
0029152811
-
Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces
-
Lorant DE, McEver RP, McIntyre TM, et al.: Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces. J Clin Invest 1995, 96:171-182.
-
(1995)
J Clin Invest
, vol.96
, pp. 171-182
-
-
Lorant, D.E.1
McEver, R.P.2
McIntyre, T.M.3
-
29
-
-
0030994536
-
Leukocyte activation induces surface redistribution of P-selectin glycoprotein ligand-1
-
Bruehl RE, Moore KL, Lorant DE, et al.: Leukocyte activation induces surface redistribution of P-selectin glycoprotein ligand-1. J Leukoc Biol 1997, 61:489-499.
-
(1997)
J Leukoc Biol
, vol.61
, pp. 489-499
-
-
Bruehl, R.E.1
Moore, K.L.2
Lorant, D.E.3
-
30
-
-
0035964329
-
Two by two: The pairings of P-selectin and P-selectin glycoprotein ligand 1
-
Zimmerman GA: Two by two: the pairings of P-selectin and P-selectin glycoprotein ligand 1. Proc Natl Acad Sci U S A 2001, 98:10023-10024.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10023-10024
-
-
Zimmerman, G.A.1
-
31
-
-
0037135977
-
Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow
-
Yago T, Leppanen A, Qiu H, et al.: Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow. J Cell Biol 2002, 156:767-799. •• The authors coupled PSGL-1 or other structurally defined selectin ligands to microspheres or the surfaces of surrogate cells and examined their behavior in rolling assays, Cellular components conferred rolling that was more uniform, shear resistant, and similar to that of leukocytes as shear forces were increased.
-
(2002)
J Cell Biol
, vol.156
, pp. 767-799
-
-
Yago, T.1
Leppanen, A.2
Qiu, H.3
-
32
-
-
0036117531
-
Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation
-
Schon MP, Krahn T, Schon M, et al.: Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation. Nat Med 2002, 8:366-372.
-
(2002)
Nat Med
, vol.8
, pp. 366-372
-
-
Schon, M.P.1
Krahn, T.2
Schon, M.3
-
33
-
-
0036218902
-
P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow
-
Xia L, Sperandio M, Yago T, et al.: P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. J Clin Invest 2002, 109:939-950. •• Using gene targeting to delete PSGL-1 in mice, the authors show that it tethers leukocytes to E-selectin. Although the PSGL-deficient leukocytes tethered poorly, the few cells that were able to establish tethers rolled normally, suggesting separate functions for distinct E-selectin ligands. This is the first evidence that PSGL-1 is recognized by E-selectin under physiologically relevant conditions.
-
(2002)
J Clin Invest
, vol.109
, pp. 939-950
-
-
Xia, L.1
Sperandio, M.2
Yago, T.3
-
34
-
-
0036604097
-
Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots
-
Fuhlbrigge RC, King SL, Dimitroff CJ, et al.: Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots. J Immunol 2002, 168:5645-5651.
-
(2002)
J Immunol
, vol.168
, pp. 5645-5651
-
-
Fuhlbrigge, R.C.1
King, S.L.2
Dimitroff, C.J.3
-
35
-
-
0037103146
-
L-selectin serves as an E-selectin ligand on cultured human T lymphoblasts
-
Jutila MA, Kurk S, Jackiw L, et al.: L-selectin serves as an E-selectin ligand on cultured human T lymphoblasts. J Immunol 2002, 169:1768-1773.
-
(2002)
J Immunol
, vol.169
, pp. 1768-1773
-
-
Jutila, M.A.1
Kurk, S.2
Jackiw, L.3
-
36
-
-
0034910611
-
The alpha(1,3)fucosyltrans-ferases FucT-IV and FucT-VII exert collaborative control over selectindependent leukocyte recruitment and lymphocyte homing
-
Homeister JW, Thall AD, Petryniak B, et al.: The alpha(1,3)fucosyltrans-ferases FucT-IV and FucT-VII exert collaborative control over selectindependent leukocyte recruitment and lymphocyte homing. Immunity 2001, 15:115-126.
-
(2001)
Immunity
, vol.15
, pp. 115-126
-
-
Homeister, J.W.1
Thall, A.D.2
Petryniak, B.3
-
37
-
-
0035801605
-
Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes
-
Smithson G, Rogers CE, Smith PL, et al.: Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes. J Exp Med 2001, 194:601-614.
-
(2001)
J Exp Med
, vol.194
, pp. 601-614
-
-
Smithson, G.1
Rogers, C.E.2
Smith, P.L.3
-
38
-
-
0036498850
-
Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs
-
Erdmann I, Scheidegger EP, Koch FK, et al.: Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs. J Immunol 2002, 168:2139-2146. •• Mice deficient for α-1,3-fucosyltransferase VII were examined in several inflammatory models that indicated that selectins and their ligands are critical for lymphocyte homing to inflamed skin but not for extravasation in certain visceral organs. The collaborative report is one in a series of important studies of the effects of deletion fucosylation pathways. See [36,37,39**].
-
(2002)
J Immunol
, vol.168
, pp. 2139-2146
-
-
Erdmann, I.1
Scheidegger, E.P.2
Koch, F.K.3
-
39
-
-
0037135982
-
Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus
-
Smith PL, Myers JT, Rogers CE, et al.: Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus. J Cell Biol 2002, 158:801-815. •• An induced null mutation at the FX locus in mice yielded a phenotype with abnormalities of leukocytes and other manifestations of congenital disorder of glycosylation IIc, also termed LAD type II. See [1*].
-
(2002)
J Cell Biol
, vol.158
, pp. 801-815
-
-
Smith, P.L.1
Myers, J.T.2
Rogers, C.E.3
-
40
-
-
0026004729
-
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: A juxtacrine system for adhesion and activation of neutrophils
-
Lorant DE, Patel KD, McIntyre TM, et al.: Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991, 115:223-234.
-
(1991)
J Cell Biol
, vol.115
, pp. 223-234
-
-
Lorant, D.E.1
Patel, K.D.2
McIntyre, T.M.3
-
42
-
-
0031913666
-
Stimulation of P-selectin glycoprotein ligand-1 on mouse neutrophils activates beta 2-integrin mediated cell attachment to ICAM-1
-
Blanks JE, Moll T, Eytner R, et al.: Stimulation of P-selectin glycoprotein ligand-1 on mouse neutrophils activates beta 2-integrin mediated cell attachment to ICAM-1. Eur J Immunol 1998, 28:433-443.
-
(1998)
Eur J Immunol
, vol.28
, pp. 433-443
-
-
Blanks, J.E.1
Moll, T.2
Eytner, R.3
-
43
-
-
0035478705
-
Immobilized IL-8 triggers progressive activation of neutrophils rolling in vitro on P-selectin and intercellular adhesion molecule-1
-
DiVietro JA, Smith MJ, Smith BR, et al.: Immobilized IL-8 triggers progressive activation of neutrophils rolling in vitro on P-selectin and intercellular adhesion molecule-1. J Immunol 2001, 167:4017-4025. •• An analysis using interleukin-8 immobilized at different site densities together with P-selectin and ICAM-1 indicated that PMNs may require binding of CXC chemokine receptors to a critical number of interleukin-8 molecules presented at the vessel wall to signal sufficient high-avidity bonds for arrest. Binding of immobilized interleukin-8 to its receptors is facilitated by engagement of PSGL-1.
-
(2001)
J Immunol
, vol.167
, pp. 4017-4025
-
-
DiVietro, J.A.1
Smith, M.J.2
Smith, B.R.3
-
44
-
-
0034655225
-
Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway
-
Simon SI, Hu Y, Vestweber D, et al.: Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway. J Immunol 2000, 164:4348-4358.
-
(2000)
J Immunol
, vol.164
, pp. 4348-4358
-
-
Simon, S.I.1
Hu, Y.2
Vestweber, D.3
-
45
-
-
0028913968
-
Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion: Signal integration and NF-kappa B translocation
-
Weyrich AS, McIntyre TM, McEver RP, et al.: Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion: signal integration and NF-kappa B translocation. J Clin Invest 1995, 95:2297-2303.
-
(1995)
J Clin Invest
, vol.95
, pp. 2297-2303
-
-
Weyrich, A.S.1
McIntyre, T.M.2
McEver, R.P.3
-
46
-
-
0030661712
-
Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils
-
Hidari KI, Weyrich AS, Zimmerman GA, et al.: Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils. J Biol Chem 1997, 272:28750-28756.
-
(1997)
J Biol Chem
, vol.272
, pp. 28750-28756
-
-
Hidari, K.I.1
Weyrich, A.S.2
Zimmerman, G.A.3
-
47
-
-
0035964340
-
Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes
-
Mahoney TS, Weyrich AS, Dixon DA, et al.: Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes. Proc Natl Acad Sci U S A 2001, 98:10284-10289. •• Engagement of PSGL-1 by immobilized P-selectin induced rapid synthesis and surface expression of urokinase plasminogen activator receptor from constitutive mRNA transcripts in human monocytes, as did adhesive interactions between monocytes and activated platelets. Rapid synthesis of urokinase plasminogen activator receptor is regulated by the mammalian target of rapamycin pathway and confers new recognition of vitronectin, providing a potential mechanism by which PSGL-1 engagement conditions monocytes for adhesion to subendothelial matrix. In addition to this new posttranscriptional pathway, engagement of PSGL-1 triggered upregulation of multiple mRNAs when examined by expression array analysis.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10284-10289
-
-
Mahoney, T.S.1
Weyrich, A.S.2
Dixon, D.A.3
-
48
-
-
0029993531
-
Activated platelets signal chemokine synthesis by human monocytes
-
Weyrich AS, Elstad MR, McEver RP, et al.: Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest 1996, 97:1525-1534.
-
(1996)
J Clin Invest
, vol.97
, pp. 1525-1534
-
-
Weyrich, A.S.1
Elstad, M.R.2
McEver, R.P.3
-
49
-
-
0001768648
-
Platelet-activating factor: A signaling molecule for leukocyte adhesion
-
Edited by Pearson J. Basel: Birkhauser
-
Lorant D, McIntyre T, Prescott S, et al.: Platelet-activating factor: a signaling molecule for leukocyte adhesion. In Vascular Adhesion Molecules and Inflammation. Edited by Pearson J. Basel: Birkhauser; 1999:81-107.
-
(1999)
Vascular Adhesion Molecules and Inflammation
, pp. 81-107
-
-
Lorant, D.1
McIntyre, T.2
Prescott, S.3
-
50
-
-
0031201732
-
Human endothelial cells synthesize ENA-78: Relation to IL-8 and to signaling of PMN adhesion
-
Imaizumi T, Albertine KH, Jicha DL, et al.: Human endothelial cells synthesize ENA-78: relation to IL-8 and to signaling of PMN adhesion. Am J Respir Cell Mol Biol 1997, 17:181-192.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 181-192
-
-
Imaizumi, T.1
Albertine, K.H.2
Jicha, D.L.3
-
51
-
-
0034653533
-
Leukocyte arrest during cytokine-dependent inflammation in vivo
-
Kunkel EJ, Dunne JL, Ley K: Leukocyte arrest during cytokine-dependent inflammation in vivo. J Immunol 2000, 164:3301-3308.
-
(2000)
J Immunol
, vol.164
, pp. 3301-3308
-
-
Kunkel, E.J.1
Dunne, J.L.2
Ley, K.3
-
52
-
-
33750712085
-
Endothelial-borne platelet-activating factor and interleukin-8 rapidly immobilize rolling neutrophils
-
Rainger GE, Fisher AC, Nash GB: Endothelial-borne platelet-activating factor and interleukin-8 rapidly immobilize rolling neutrophils. Am J Physiol 1997, 272:H114-H122.
-
(1997)
Am J Physiol
, vol.272
-
-
Rainger, G.E.1
Fisher, A.C.2
Nash, G.B.3
-
53
-
-
0030704740
-
Transcytosis and surface presentation of IL-8 by venular endothelial cells
-
Middleton J, Neil S, Wintle J, et al.: Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 1997, 91:385-395.
-
(1997)
Cell
, vol.91
, pp. 385-395
-
-
Middleton, J.1
Neil, S.2
Wintle, J.3
-
54
-
-
0035905495
-
Shear-dependent eosinophil transmigration on interleukin 4-stimulated endothelial cells: A role for endothelium-assooiated eotaxin-3
-
Cuvelier SL, Patel KD: Shear-dependent eosinophil transmigration on interleukin 4-stimulated endothelial cells: a role for endothelium-assooiated eotaxin-3. J Exp Med 2001, 194:1699-1709. •• The authors describe a new mechanism of eosinophil recruitment under shear in which eotaxin-3 is synthesized by interleukin-4-stimulated human endothelial cells. Eotaxin-3 acts as a juxtacrine signal at the endothelial surface, binding to CCR3 on the eosinophils and inducing cellular activation.
-
(2001)
J Exp Med
, vol.194
, pp. 1699-1709
-
-
Cuvelier, S.L.1
Patel, K.D.2
-
55
-
-
0035158575
-
Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues
-
Palframan RT, Jung S, Cheng G, et al.: Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J Exp Med 2001, 194:1361-1373. •• These experiments describe a "remote control" mechanism in which monocyte chemotactic protein-1 synthesized in distant inflamed skin is transported to the surfaces of endothelial cells in regional lymph nodes and triggers integrin-dependent arrest of rolling monocytes in a murine model. See [56*].
-
(2001)
J Exp Med
, vol.194
, pp. 1361-1373
-
-
Palframan, R.T.1
Jung, S.2
Cheng, G.3
-
56
-
-
0035163745
-
Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment
-
Janatpour MJ, Hudak S, Sathe M, et al.: Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment. J Exp Med 2001, 194:1375-1384. • The authors describe a mechanism of local chemokine synthesis by a subset of high endothelial venules leading to cellular signaling and monocyte recruitment in regional lymph nodes of mice subjected to inflammatory challenge. A tumor necrosis factor-α-dependent component of the inflammatory process controlled the pattern of chemokines expressed on high endothelial venules in these murine lines. See [55**].
-
(2001)
J Exp Med
, vol.194
, pp. 1375-1384
-
-
Janatpour, M.J.1
Hudak, S.2
Sathe, M.3
-
57
-
-
0037126048
-
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury
-
Schober A, Manka D, von Hundelshausen BS, et al.: Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury. Circulation 2002, 106:1523-1529. •• The authors describe a complex "give-and-go" mechanism in which the CC chemokine RANTES is translocated to the surfaces of inflamed arterial endothelial cells and mediates recruitment of monocytes. The transfer was dependent on cell-cell interactions that involve platelet, but not endothelial, P-selectin and suggests that a ligand recognized by platelet P-selectin is induced on endothelial cells stimulated with interleukin-1 β in addition to a binding partner for RANTES. Additional aspects of these complex cell-cell interactions are discussed in [59].
-
(2002)
Circulation
, vol.106
, pp. 1523-1529
-
-
Schober, A.1
Manka, D.2
Von Hundelshausen, B.S.3
-
58
-
-
0029171087
-
The interaction of leukocytes with platelets in blood coagulation
-
Elstad MR, McIntyre TM, Prescott SM, et al.: The interaction of leukocytes with platelets in blood coagulation. Curr Opin Hematol 1995, 2:47-54.
-
(1995)
Curr Opin Hematol
, vol.2
, pp. 47-54
-
-
Elstad, M.R.1
McIntyre, T.M.2
Prescott, S.M.3
-
59
-
-
0037126014
-
Platelets, endothelial cells, inflammatory chemokines, and restenosis: Complex signaling in the vascular play book
-
Weyrich AS, Prescott SM, Zimmerman CA: Platelets, endothelial cells, inflammatory chemokines, and restenosis: complex signaling in the vascular play book. Circulation 2002, 106:1433-1435.
-
(2002)
Circulation
, vol.106
, pp. 1433-1435
-
-
Weyrich, A.S.1
Prescott, S.M.2
Zimmerman, C.A.3
-
60
-
-
0035817627
-
Activated platelets mediate inflammatory signaling by regulated interleukin 1 beta synthesis
-
3-integrins on the platelets, suggesting a new mode of action of antithrombotic agents in inflammatory syndromes.
-
(2001)
J Cell Biol
, vol.154
, pp. 485-490
-
-
Lindemann, S.1
Tolley, N.D.2
Dixon, D.A.3
-
61
-
-
0036624734
-
Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity
-
2-integrins. The authors reported antigenic characterization of endothelial microparticles in an earlier study and showed that they are increased in the blood of patients with pathologic thrombosis.
-
(2002)
Blood
, vol.99
, pp. 3962-3970
-
-
Sabatier, F.1
Roux, V.2
Anfosso, F.3
-
63
-
-
0037009042
-
Integrin activation takes shape
-
Liddington RC, Ginsberg MH:Integrin activation takes shape. J Cell Biol 2002, 158:833-839. • A topical review of the known and unknown aspects of integrin activation.
-
(2002)
J Cell Biol
, vol.158
, pp. 833-839
-
-
Liddington, R.C.1
Ginsberg, M.H.2
-
64
-
-
0034744558
-
Functional alpha4-integrin: A newly identified pathway of neutrophil recruitment in critically ill septic patients
-
2-integrin-mediated adhesion triggered by a factor in septic plasma.
-
(2001)
Nat Med
, vol.7
, pp. 465-470
-
-
Ibbotson, G.C.1
Doig, C.2
Kaur, J.3
-
65
-
-
0025361725
-
Human neutrophil adherence to laminin in vitro: Evidence for a distinct neutrophil integrin receptor for laminin
-
Bohnsack JF, Akiyama SK, Damsky CH, et al.: Human neutrophil adherence to laminin in vitro: evidence for a distinct neutrophil integrin receptor for laminin. J Exp Meal 1990, 171:1221-1237.
-
(1990)
J Exp Meal
, vol.171
, pp. 1221-1237
-
-
Bohnsack, J.F.1
Akiyama, S.K.2
Damsky, C.H.3
-
66
-
-
0036008013
-
JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes
-
2-integrin (MAC-1, CD11 b/CD18), which recognizes ICAM-1 but not JAM-1.
-
(2002)
Nat Immunol
, vol.3
, pp. 151-158
-
-
Ostermann, G.1
Weber, K.S.2
Zernecke, A.3
-
67
-
-
0037100270
-
Intercellular adhesion molecule (ICAM)-1, but not ICAM-2, activates RhoA and stimulates c-fos and rhoA transcription in endothelial cells
-
Thompson PW, Randi AM, Ridley AJ: Intercellular adhesion molecule (ICAM)-1, but not ICAM-2, activates RhoA and stimulates c-fos and rhoA transcription in endothelial cells. J Immunol 2002, 169:1007-1013.
-
(2002)
J Immunol
, vol.169
, pp. 1007-1013
-
-
Thompson, P.W.1
Randi, A.M.2
Ridley, A.J.3
-
68
-
-
0037166942
-
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes
-
Barreiro O, Yanez-Mo M, Serrador JM, et al.: Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol 2002, 157:1233-1245.
-
(2002)
J Cell Biol
, vol.157
, pp. 1233-1245
-
-
Barreiro, O.1
Yanez-Mo, M.2
Serrador, J.M.3
-
69
-
-
0034284237
-
Activation of human leukocytes reduces surface P-selectin glycoprotein ligand-1 (PSGL-1, CD162) and adhesion to P-selectin in vitro
-
Davenpeck KL, Brummet ME, Hudson SA, et al.: Activation of human leukocytes reduces surface P-selectin glycoprotein ligand-1 (PSGL-1, CD162) and adhesion to P-selectin in vitro. J Immunol 2000, 165:2764-2772.
-
(2000)
J Immunol
, vol.165
, pp. 2764-2772
-
-
Davenpeck, K.L.1
Brummet, M.E.2
Hudson, S.A.3
-
70
-
-
0036721793
-
Requirement for RhoA kinase activation in leukocyte de-adhesion
-
Liu L, Schwartz BR, Lin N, et al.: Requirement for RhoA kinase activation in leukocyte de-adhesion. J Immunol 2002, 169:2330-2336.
-
(2002)
J Immunol
, vol.169
, pp. 2330-2336
-
-
Liu, L.1
Schwartz, B.R.2
Lin, N.3
-
71
-
-
0036167093
-
CD99 plays a major role in the migration of monocytes through endothelial junctions
-
Schenkel AR, Mamdouh Z, Chen X, et al.: CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat Immunol 2002, 3:143-150. •• CD99 has newly recognized roles in the transmigration of monocytes through endothelial junctions, acting in sequence with PECAM-1.
-
(2002)
Nat Immunol
, vol.3
, pp. 143-150
-
-
Schenkel, A.R.1
Mamdouh, Z.2
Chen, X.3
-
72
-
-
0026725537
-
Cytokine regulation of endothelial cell function
-
Mantovani A, Bussolino F, Dejana E: Cytokine regulation of endothelial cell function. FASEB J 1992, 6:2591-2599.
-
(1992)
FASEB J
, vol.6
, pp. 2591-2599
-
-
Mantovani, A.1
Bussolino, F.2
Dejana, E.3
-
73
-
-
0035570686
-
Neutrophil enhancement of fibrin deposition under flow through platelet-dependent and -independent mechanisms
-
Goel MS, Diamond SL: Neutrophil enhancement of fibrin deposition under flow through platelet-dependent and -independent mechanisms. Arterioscler Thromb Vasc Biol 2001, 21:2093-2098.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 2093-2098
-
-
Goel, M.S.1
Diamond, S.L.2
-
74
-
-
0036241926
-
Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTESdependent firm adhesion of leukocytes
-
Mack M, Pfirstinger J, Weber C, et al.: Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTESdependent firm adhesion of leukocytes. Eur J Immunol 2002, 32:1012-1020.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1012-1020
-
-
Mack, M.1
Pfirstinger, J.2
Weber, C.3
-
75
-
-
0035658374
-
Platelets modulate ischemia/reperfusion-induced leukocyte recruitment in the mesenteric circulation
-
Salter JW, Krieglstein CF, Issekutz AC, et al.: Platelets modulate ischemia/reperfusion-induced leukocyte recruitment in the mesenteric circulation. Am J Physiol Gastrointest Liver Physiol 2001, 281:G1432-G1439. • The authors used blocking strategies and intravital microscopy in a rat model of vessel injury and found evidence that platelet-associated P-selectin contributes to recruitment of leukocytes by enhancing transendothelial migration.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Salter, J.W.1
Krieglstein, C.F.2
Issekutz, A.C.3
-
76
-
-
0035166834
-
Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure
-
Singbartl K, Forlow SB, Ley K: Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure. FASEB J 2001, 15:2337-2344. • In a model using wild-type mice and chimeric mice deficient in either platelet or endothelial P-selectin, platelet P-selectin was critical for regional leukocyte recruitment in the kidneys and for postischemic renal failure.
-
(2001)
FASEB J
, vol.15
, pp. 2337-2344
-
-
Singbartl, K.1
Forlow, S.B.2
Ley, K.3
-
77
-
-
0030726989
-
Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphallbbeta3 and stimulated by platelet-activating factor
-
Weber C, Springer TA: Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphallbbeta3 and stimulated by platelet-activating factor. J Clin Invest 1997, 100:2085-2093.
-
(1997)
J Clin Invest
, vol.100
, pp. 2085-2093
-
-
Weber, C.1
Springer, T.A.2
-
78
-
-
0032523178
-
A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process
-
Ostrovsky L, King AJ, Bond S, et al.: A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process. Blood 1998, 91:3028-3036.
-
(1998)
Blood
, vol.91
, pp. 3028-3036
-
-
Ostrovsky, L.1
King, A.J.2
Bond, S.3
-
79
-
-
0031861613
-
Neutrophils rolling on immobilized platelets migrate into homotypic aggregates after activation
-
Rainger GE, Buckley C, Simmons DL, et al.: Neutrophils rolling on immobilized platelets migrate into homotypic aggregates after activation. Thromb Haemost 1998, 79:1177-1183.
-
(1998)
Thromb Haemost
, vol.79
, pp. 1177-1183
-
-
Rainger, G.E.1
Buckley, C.2
Simmons, D.L.3
-
80
-
-
0035860838
-
Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets
-
Galt SW, Lindemann S, Medd D, et al.: Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets. Circ Res 2001, 89:509-516.
-
(2001)
Circ Res
, vol.89
, pp. 509-516
-
-
Galt, S.W.1
Lindemann, S.2
Medd, D.3
-
81
-
-
0036721707
-
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration
-
Schenk BI, Petersen F, Flad HD, et al.: Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration. J Immunol 2002, 169:2602-2610.
-
(2002)
J Immunol
, vol.169
, pp. 2602-2610
-
-
Schenk, B.I.1
Petersen, F.2
Flad, H.D.3
-
82
-
-
0036250816
-
The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis
-
Zimmerman GA, McIntyre TM, Prescott SM, et al.: The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis. Crit Care Med 2002, 30:S294-S301.
-
(2002)
Crit Care Med
, vol.30
-
-
Zimmerman, G.A.1
McIntyre, T.M.2
Prescott, S.M.3
|