Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes

Journal of Experimental Medicine

Volumn 194, Issue 5, 2001, Pages 601-614

  Smithson, G ^a   Rogers, C E ^a   Smith, P L ^a   Scheidegger, P E ^a   Petryniak, B ^a   Myers, J T ^a   Kim, D S L ^a   Homeister, J W ^a   Lowe, J B ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Fucosyltransferase; Selectin; T lymphocyte; Tc1; Th1

Indexed keywords

ALPHA 1,3 FUCOSYLTRANSFERASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; LIGAND; PADGEM PROTEIN; SELECTIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CONTACT ALLERGY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; LANGERHANS CELL; LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL;

ANIMALS; CELL DIFFERENTIATION; CELL POLARITY; E-SELECTIN; FLOW CYTOMETRY; FUCOSYLTRANSFERASES; INFLAMMATION; LANGERHANS CELLS; LIGANDS; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; P-SELECTIN; SELECTINS; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS;

EID: 0035801605     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.5.601     Document Type: Article

References (50)

1. Mechanisms that regulate the function of the selectins and their ligands
2. Selectin ligands, leukocyte trafficking, and fucosyltransferase genes
3. Carbohydrate sulfotransferases in lymphocyte homing
4. Endothelial ligands for L-selectin
5. Expression cloning and characterization of a novel murine 1,3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney
6. The α(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis
7. Leukocyte rolling in non-inflamed skin venules: Role of selectins and alpha(1,3)-fucosyltransferase-IV and -VII in cutaneous immune surveillance
8. The α(1,3)fucosyltransferases Fuc-TIV and Fuc-TVII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing
9. Interleukin 12 and interleukin 4 control T cell adhesion to endothelial selectins through opposite effects on α1,3-fucosyltransferase VII gene expression
10. The fucosyl-transferase FucT-VII regulates E-selectin ligand synthesis in human T cells
11. α(1,3)-fucosyltransferase VII and α(2,3)-sialyltrans-ferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites
12. Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-4
13. Differential expression of alpha3 fucosyltransferases in Th1 and Th2 cells correlates with their ability to bind P-selectin
14. Langerhans' cell expression of the selectin ligand, sialyl Lewis x
15. Interaction of dendritic cells with skin endothelium: A new perspective on immunosurveillance
16. Tolerance and contact sensitivity to DNFB in mice. I. In vivo detection by ear swelling and correlation with in vitro cell stimulation
17. Dendritic cells require T cells for functional maturation in vivo
18. Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate
19. + T cells
20. + subsets
21. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB
22. Antigen-bearing Langerhans cells in skin, dermal lymphatics and in lymph nodes
23. A skin homing molecule defines the Langerhans cell progenitor in human peripheral blood
24. Expression of maturation-/migration-related molecules on human dendritic cells from blood and skin
25. Impaired primary T cell responses in L-selectin -deficient mice
26. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice
27. The route of antigen entry determines the requirement for L-selectin during immune responses
28. Entry of Naive CD4 T cells into peripheral lymph nodes requires L-selectin
29. + T cells
30. + effector T cells in vivo: Immunization results in a transient population of Mel-14-CD45RB- helper cells that secrete interleukin 2(IL-2), IL-3, IL-4, and interferon γ
31. Intrinsic differences in L-selectin expression levels affect T and B lymphocyte subset-specific recirculation pathways
32. The entry of lymphocytes into stimulated lymph nodes. The site of selection of alloantigen-specific cells
33. Selective modulation of the expression of L-selectin ligands by an immune response
34. The expanding universe of T-cell subsets: Th1, Th2 and more
35. Two types of murine helper T cell clone II. Delayed-type hypersensitivity is mediated by Th1 clones
36. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion
37. P-selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration
38. P-and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues
39. + T cells migrate into inflamed skin only if they express ligands for E-and P-selectin
40. P-selectin glycoprorein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin
41. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
42. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
43. Preferential localization of effector memory cells in nonlymphoid tissue
44. Visualizing the generation of memory CD4 T cells in the whole body
45. Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice
46. Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin
47. Groalpha-mediated recruitment of neutrophils is required for elicitation of contact hypersensitivity
48. Characterization of the E-selectin-deficient mice: Demonstration of overlapping function of the endothelial selectins
49. Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: Participation of E- and P- but not L-selectin