Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation

Nature Medicine

Volumn 8, Issue 4, 2002, Pages 366-372

  Schön, Michael P ^a   Krahn, Thomas ^b   Schön, Margarete ^a   Rodriguez, Maria L ^b   Antonicek, Horst ^b   Schultz, Jeanette E ^c   Ludwig, Ralf J ^c   Zollner, Thomas M ^c   Bischoff, Erwin ^b   Bremm, Klaus D ^b   Schramm, Matthias ^b   Henninger, Kerstin ^b   Kaufmann, Roland ^c   Gollnick, Harald P M ^a   Parker, Christina M ^d   Boehncke, W Henning ^c  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b BAYER AG   (Germany)

^c GOETHE UNIVERSITY   (Germany)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EFOMYCINE A; EFOMYCINE B; EFOMYCINE E; EFOMYCINE G; EFOMYCINE M; SELECTIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG CONFORMATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LEUKOCYTE ADHERENCE; MICROSCOPY; MOLECULAR BIOLOGY; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PSORIASIS; SKIN INFLAMMATION; VENULE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL ADHESION; CELL MOVEMENT; E-SELECTIN; FEMALE; HUMANS; LEUKOCYTES; MACROLIDES; MICE; MICE, INBRED C57BL; MICE, SCID; MODELS, MOLECULAR; OLIGOSACCHARIDES; PSORIASIS; SKIN TRANSPLANTATION; STREPTOMYCES; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA;

EID: 0036117531     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0402-366     Document Type: Article

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