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Volumn 38, Issue 1, 2003, Pages 89-100
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Synthesis and preliminary evaluation of some N-[5-(2-furanyl)-2-methyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl]-carboxamide and 3-substituted-5-(2-furanyl)-2-methyl-3H-thieno[2,3-d]pyrimidin-4-ones as antimicrobial agents
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Author keywords
Antibacterial and Antimycobacterial activity; Hemolytic assay; MIC (minimum inhibitory concentration); Synthesis; Thieno 2,3 d pyrimidin 4 one
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Indexed keywords
2 FURYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]ACETAMIDE;
2 THIENYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]ACETAMIDE;
2,4 DICHLORO N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
2,4 DIFLUORO N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
3 (BENZYLIDENEAMINO) 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 (CYCLOHEXYLMETHYLENEAMINO) 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 (CYCLOPROPYLMETHYLENEAMINO) 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 ETHYLIDENEAMINO 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(2,4 CHLOROBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(2,4 FLUOROBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(4 CHLOROBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(4 FLUOROBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(4 METHOXYBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(4 METHYLBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(4 NITROBENZYLIDENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(FURAN 2 YLMETHYLENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
3 [(THIOPHEN 2 YLMETHYLENE)AMINO] 5 (2 FURANYL) 2 METHYL 3H THIENO[2,3 D]PYRIMIDIN 4 ONE;
4 CHLORO N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
4 FLUORO N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
4 METHOXY N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
4 METHYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
4 NITRO N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
AMIDE;
ANTIINFECTIVE AGENT;
CYCLOHEXYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]ACETAMIDE;
CYCLOPROPYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]ACETAMIDE;
METHYL N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]ACETAMIDE;
N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]BENZAMIDE;
N [5 (2 FURANYL) 2 METHYL 4 OXO 4H THIENO[2,3 D]PYRIMIDIN 3 YL]CARBOXAMIDE;
PYRIMIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
AMINO ACID SUBSTITUTION;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BACILLUS SUBTILIS;
BACTERIAL STRAIN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SYNTHESIS;
ESCHERICHIA COLI;
GRAM NEGATIVE BACTERIUM;
IN VITRO STUDY;
NONHUMAN;
SALMONELLA TYPHI;
STAPHYLOCOCCUS AUREUS;
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EID: 0037366454
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(02)01442-3 Document Type: Article |
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Times cited : (186)
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References (29)
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