Synthesis and activity of phenyl derivatives containing 5,6-dimethyl-thieno [2,3-d] pyrimidin-4(1H)-one or 4H-pyrimido [5,4-b] indol-4-one heterocyclic system as potential non steroidal anti-inflammatory drugs

Arzneimittel-Forschung/Drug Research

Volumn 52, Issue 6, 2002, Pages 448-454

  Santagati, Andrea ^a   Granata, Giuseppe ^a   Santagati, Maria ^a   Cutuli, Vincenza ^a   Mangano, Nunzio Guido ^a   Caruso, Antonina ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

4H Pyrimido 5,4 b indol 4 one phenyl derivatives, pharmacology, synthesis; 5,6 Dimethyl thieno 2,3 d pyrimidin 4(1H) one phenyl derivatives, pharmacology, synthesis; Analgesics; Anti inflammatories, non steroidal

Indexed keywords

4H PYRIMIDO[5,4 B]INDOL 4 ONE; 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(1H) ONE; 6,7 DIMETHYL 2 PHENYL 8H [1,3,4]THIADIAZOLO[3,2 A]THIENO[2,3 D]PYRIMIDIN 8 ONE; ANALGESIC AGENT; BENZENE DERIVATIVE; HETEROCYCLIC COMPOUND; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLBUTAZONE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; [(3 AMINO 3,5 TRIHYDRO 4 OXO 4H PYRIMIDO[5,4 B]INDOL 2 YL)THIO]PHENYLACETIC ACID;

ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; RAT;

EID: 0036282668     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1299913     Document Type: Article

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