-
1
-
-
0034119046
-
Diptheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias
-
Frankel, A. E., McCubrey, J. A., Miller, M. S., Delatte, S., Ramage, J., Kiser, M., Kucera, G. L., Alexander, R. L., Beran, M., Tagge, E. P., Kreitman, R. J., and Hogge, D. E. Diptheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias. Leukemia, 14: 576-585, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 576-585
-
-
Frankel, A.E.1
McCubrey, J.A.2
Miller, M.S.3
Delatte, S.4
Ramage, J.5
Kiser, M.6
Kucera, G.L.7
Alexander, R.L.8
Beran, M.9
Tagge, E.P.10
Kreitman, R.J.11
Hogge, D.E.12
-
2
-
-
0035016885
-
Anticancer drug resistance in primary human brain tumors
-
Bredel, M. Anticancer drug resistance in primary human brain tumors. Brain Res. Brain Res. Rev., 35: 161-204, 2001.
-
(2001)
Brain Res. Brain Res. Rev.
, vol.35
, pp. 161-204
-
-
Bredel, M.1
-
3
-
-
0035399588
-
Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function
-
Chen, Z-S., Aoki, S., Komatsu, M., Ueda, K., Sumizawa, T., Furukawa, T., Okumura, H., Ren, X-Q., Belinsky, M. G., Lee, K., Kruh, G. D., Kobayashi, M., and Akiyama, S. Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function. Int. J. Cancer, 93: 107-113, 2001.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 107-113
-
-
Chen, Z.-S.1
Aoki, S.2
Komatsu, M.3
Ueda, K.4
Sumizawa, T.5
Furukawa, T.6
Okumura, H.7
Ren, X.-Q.8
Belinsky, M.G.9
Lee, K.10
Kruh, G.D.11
Kobayashi, M.12
Akiyama, S.13
-
4
-
-
0034899450
-
Suppression of apoptosis: Role in cell growth and neoplasia
-
White, M. K., and McCubrey, J. A. Suppression of apoptosis: role in cell growth and neoplasia. Leukemia, 15: 1011-1021, 2001.
-
(2001)
Leukemia
, vol.15
, pp. 1011-1021
-
-
White, M.K.1
McCubrey, J.A.2
-
5
-
-
0034805181
-
Overexpression of Bcl-2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
-
Sun, S-Y., Yue, P., Zhou, J-Y., Wang, Y., Choi Kim, H-R., Lotan, R., and Wu, G. S. Overexpression of Bcl-2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem. Biophys. Res. Commun., 280: 788-797, 2001.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 788-797
-
-
Sun, S.-Y.1
Yue, P.2
Zhou, J.-Y.3
Wang, Y.4
Choi Kim, H.-R.5
Lotan, R.6
Wu, G.S.7
-
6
-
-
0001822830
-
Signal transduction pathways: Cytokine model
-
M. V. Blagosklonny (ed.). Georgetown, TX: Landes Bioscience
-
McCubrey, J. A., Blalock, W. L., Chang, F., Steelman, L. S., Pohnert, S. C., Navolanic, P. M., Shelton, J. G., Hoyle, P. E., Moye, P. W., Oberhaus, S. M., White, M. K., Lee, J. T., and Franklin, R. A. Signal transduction pathways: cytokine model. In: M. V. Blagosklonny (ed.), Cell Cycle Checkpoints and Cancer, pp. 17-53. Georgetown, TX: Landes Bioscience, 2001.
-
(2001)
Cell Cycle Checkpoints and Cancer
, pp. 17-53
-
-
McCubrey, J.A.1
Blalock, W.L.2
Chang, F.3
Steelman, L.S.4
Pohnert, S.C.5
Navolanic, P.M.6
Shelton, J.G.7
Hoyle, P.E.8
Moye, P.W.9
Oberhaus, S.M.10
White, M.K.11
Lee, J.T.12
Franklin, R.A.13
-
7
-
-
17944368285
-
Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells
-
McCubrey, J. A., Blalock, W. L., Saleh, O., Pearce, M., Burrows, C., Steelman, L. S., Lee, J. T., Franklin, R. A., Oberhaus, S. M., Moye, P. W., Doshi, P. D., and McKearn, J. P. Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells. Leukemia, 15: 1203-1216, 2001.
-
(2001)
Leukemia
, vol.15
, pp. 1203-1216
-
-
McCubrey, J.A.1
Blalock, W.L.2
Saleh, O.3
Pearce, M.4
Burrows, C.5
Steelman, L.S.6
Lee, J.T.7
Franklin, R.A.8
Oberhaus, S.M.9
Moye, P.W.10
Doshi, P.D.11
McKearn, J.P.12
-
8
-
-
0028915454
-
Regulation of lymphocyte survival by the Bcl-2 gene family
-
Cory, S. Regulation of lymphocyte survival by the Bcl-2 gene family. Annu. Rev. Immunol., 13: 513-543, 1995.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 513-543
-
-
Cory, S.1
-
9
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salveson, G. S., and Dixit, V. M. Caspases: intracellular signaling by proteolysis. Cell, 91: 443-446, 1997.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salveson, G.S.1
Dixit, V.M.2
-
10
-
-
0028017880
-
Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system
-
Sato, T., Hanada, M., Bodrug, S., Irie, S., Iwama, N., Boise, L. H., Thompson, C. B., Golemis, E., Fong, L., Wang, H-G., and Reed, J. C. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proc. Natl. Acad. Sci. USA, 91: 9238-9242, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9238-9242
-
-
Sato, T.1
Hanada, M.2
Bodrug, S.3
Irie, S.4
Iwama, N.5
Boise, L.H.6
Thompson, C.B.7
Golemis, E.8
Fong, L.9
Wang, H.-G.10
Reed, J.C.11
-
11
-
-
0028944271
-
Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-α expression in tumor cells correlates with resistance towards apoptosis
-
Bargou, R. C., Daniel, P. T., Mapara, M. Y., Bommer, K., Wagener, C., Kallinich, B., Royer, H. D., and Dörken, B. Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-α expression in tumor cells correlates with resistance towards apoptosis. Int. J. Cancer, 60: 854-859, 1995.
-
(1995)
Int. J. Cancer
, vol.60
, pp. 854-859
-
-
Bargou, R.C.1
Daniel, P.T.2
Mapara, M.Y.3
Bommer, K.4
Wagener, C.5
Kallinich, B.6
Royer, H.D.7
Dörken, B.8
-
12
-
-
0029032660
-
Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax
-
Hanada, M., Aimé-Sempé, C., Sato, T., and Reed, J. C. Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax. J. Biol. Chem., 270: 11962-11969, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11962-11969
-
-
Hanada, M.1
Aimé-Sempé, C.2
Sato, T.3
Reed, J.C.4
-
13
-
-
0030047365
-
Functional dissection of the human Bcl2 protein: Sequence requirements for inhibition of apoptosis
-
Hunter, J. J., Bond, B. L., and Parslow, T. G. Functional dissection of the human Bcl2 protein: sequence requirements for inhibition of apoptosis. Mol. Cell. Biol., 16: 877-883, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 877-883
-
-
Hunter, J.J.1
Bond, B.L.2
Parslow, T.G.3
-
14
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer, G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med., 3: 614-620, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
15
-
-
0030614915
-
L-Bak peptide complex: Recognition between regulators of apoptosis
-
L-Bak peptide complex: recognition between regulators of apoptosis. Science (Wash. DC), 275: 983-986, 1997.
-
(1997)
Science (Wash. DC)
, vol.275
, pp. 983-986
-
-
Sattler, M.1
Liang, H.2
Nettesheim, D.3
Meadows, R.P.4
Harlan, J.E.5
Eberstadt, M.6
Yoon, H.S.7
Shucker, S.B.8
Chang, B.S.9
Minn, A.J.10
Thompson, C.B.11
Fesik, S.W.12
-
16
-
-
0034805754
-
Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein
-
Antoku, K., Maser, R. S., Scully, W. J., Jr., Delach, S. M., and Johnson, D. E. Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein. Biochem. Biophys. Res. Commun., 286: 1003-1010, 2001.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.286
, pp. 1003-1010
-
-
Antoku, K.1
Maser, R.S.2
Scully W.J., Jr.3
Delach, S.M.4
Johnson, D.E.5
-
17
-
-
0021934042
-
H on chromosome 14 and near a transcriptional unit on 18
-
H on chromosome 14 and near a transcriptional unit on 18. Cell, 41: 899-906, 1985.
-
(1985)
Cell
, vol.41
, pp. 899-906
-
-
Bakhshi, A.1
Jensen, J.P.2
Goldman, P.3
Wright, J.J.4
McBride, O.W.5
Epstein, A.L.6
Korsmeyer, S.J.7
-
18
-
-
0029937303
-
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
-
Wang, H-G., Takayama, A., Rapp, U. R., and Reed, J. C. Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc. Natl. Acad. Sci. USA, 93: 7063-7068, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7063-7068
-
-
Wang, H.-G.1
Takayama, A.2
Rapp, U.R.3
Reed, J.C.4
-
19
-
-
0034525423
-
Kinases: Positive and negative regulators of apoptosis
-
Franklin, R. A., and McCubrey, J. A. Kinases: positive and negative regulators of apoptosis. Leukemia, 14: 2019-2034, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 2019-2034
-
-
Franklin, R.A.1
McCubrey, J.A.2
-
20
-
-
0034987505
-
Synergistic effects of PI3K/Akt on abrogation of cytokine-dependency induced by oncogenic Raf
-
McCubrey, J. A., Steelman, L. S., Blalock, W. L., Lee, J. T., Moye, P. W., Chang, F., Pearce, M., Shelton, J. G., White, M. K., Franklin, R. A., and Pohnert, S. C. Synergistic effects of PI3K/Akt on abrogation of cytokine-dependency induced by oncogenic Raf. Adv. Enzyme Regul., 41: 289-323, 2001.
-
(2001)
Adv. Enzyme Regul.
, vol.41
, pp. 289-323
-
-
McCubrey, J.A.1
Steelman, L.S.2
Blalock, W.L.3
Lee, J.T.4
Moye, P.W.5
Chang, F.6
Pearce, M.7
Shelton, J.G.8
White, M.K.9
Franklin, R.A.10
Pohnert, S.C.11
-
21
-
-
0012453190
-
The effects of β-estradiol on Raf activity, cell cycle progression and growth factor synthesis in the MCF-7 breast cancer cell line
-
Weinstein-Oppenheimer, C. R., Burrows, C., Steelman, L. S., and McCubrey, J. A. The effects of β-estradiol on Raf activity, cell cycle progression and growth factor synthesis in the MCF-7 breast cancer cell line. Cancer Biol. Ther., 1: 256-262, 2002.
-
(2002)
Cancer Biol. Ther.
, vol.1
, pp. 256-262
-
-
Weinstein-Oppenheimer, C.R.1
Burrows, C.2
Steelman, L.S.3
McCubrey, J.A.4
-
22
-
-
0031761118
-
Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells
-
McCubrey, J. A., Steelman, L. S., Hoyle, P. E., Blalock, W. L., Weinstein-Oppenheimer, C., Franklin, R. A., Cherwinski, H., Bosch, E., and McMahon, M. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells. Leukemia, 12: 1903-1929, 1998.
-
(1998)
Leukemia
, vol.12
, pp. 1903-1929
-
-
McCubrey, J.A.1
Steelman, L.S.2
Hoyle, P.E.3
Blalock, W.L.4
Weinstein-Oppenheimer, C.5
Franklin, R.A.6
Cherwinski, H.7
Bosch, E.8
McMahon, M.9
-
23
-
-
0032874677
-
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: Possible sites for intervention with anti-neoplastic drugs
-
Blalock, W. L., Weinstein-Oppenheimer, C., Chang, F., Hoyle, P. E., Wang, X-Y., Algate, P. A., Franklin, R. A., Oberhaus, S. M., Steelman, L. S., and McCubrey, J. A. Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs. Leukemia, 13: 1109-1166, 1999.
-
(1999)
Leukemia
, vol.13
, pp. 1109-1166
-
-
Blalock, W.L.1
Weinstein-Oppenheimer, C.2
Chang, F.3
Hoyle, P.E.4
Wang, X.-Y.5
Algate, P.A.6
Franklin, R.A.7
Oberhaus, S.M.8
Steelman, L.S.9
McCubrey, J.A.10
-
24
-
-
0034130788
-
Effects of deregulated Raf and MEK1 expression on the cytokine-dependency of hematopoietic cells
-
McCubrey, J. A., Steelman, L. S., Moye, P. W., Hoyle, P. E., Weinstein-Oppenheimer, C., Chang, F., Pearce, M., White, M. K., Franklin, R., and Blalock, W. L. Effects of deregulated Raf and MEK1 expression on the cytokine-dependency of hematopoietic cells. Adv. Enzyme Regul., 40: 305-337, 2000.
-
(2000)
Adv. Enzyme Regul.
, vol.40
, pp. 305-337
-
-
McCubrey, J.A.1
Steelman, L.S.2
Moye, P.W.3
Hoyle, P.E.4
Weinstein-Oppenheimer, C.5
Chang, F.6
Pearce, M.7
White, M.K.8
Franklin, R.9
Blalock, W.L.10
-
25
-
-
0034450953
-
The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors
-
Weinstein-Oppenheimer, C. R., Blalock, W. L., Steelman, L. S., Chang, F., and McCubrey, J. A. The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors. Pharmacol. Ther., 88: 229-279, 2000.
-
(2000)
Pharmacol. Ther.
, vol.88
, pp. 229-279
-
-
Weinstein-Oppenheimer, C.R.1
Blalock, W.L.2
Steelman, L.S.3
Chang, F.4
McCubrey, J.A.5
-
26
-
-
0034719381
-
A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells
-
Blalock, W. L., Pearce, M., Steelman, L. S., Franklin, R. A., McCarthy, S. A., Cherwinski, H., McMahon, M., and McCubrey, J. A. A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells. Oncogene, 19: 526-536, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 526-536
-
-
Blalock, W.L.1
Pearce, M.2
Steelman, L.S.3
Franklin, R.A.4
McCarthy, S.A.5
Cherwinski, H.6
McMahon, M.7
McCubrey, J.A.8
-
27
-
-
0035019189
-
Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells
-
Blalock, W. L., Pearce, M., Chang, F., Lee, J. T., Pohnert, S. C., Burrows, C., Steelman, L. S., Franklin, R. A., McMahon, M., and McCubrey, J. A. Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells. Leukemia, 15: 794-807, 2001.
-
(2001)
Leukemia
, vol.15
, pp. 794-807
-
-
Blalock, W.L.1
Pearce, M.2
Chang, F.3
Lee, J.T.4
Pohnert, S.C.5
Burrows, C.6
Steelman, L.S.7
Franklin, R.A.8
McMahon, M.9
McCubrey, J.A.10
-
28
-
-
0035913161
-
Cipl induced by Raf is associated with increased Cdk4 activity in hematopoietic cells
-
Cipl induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. Oncogene, 20: 4354-4364, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 4354-4364
-
-
Chang, F.1
McCubrey, J.A.2
-
29
-
-
0034076367
-
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism
-
Hoyle, P. E., Moye, P. W., Steelman, L. S., Blalock, W. L., Franklin, R. A., Pearce, M., Cherwinski, H., Bosch, E., McMahon, M., and McCubrey, J. A. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism. Leukemia, 14: 642-656, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 642-656
-
-
Hoyle, P.E.1
Moye, P.W.2
Steelman, L.S.3
Blalock, W.L.4
Franklin, R.A.5
Pearce, M.6
Cherwinski, H.7
Bosch, E.8
McMahon, M.9
McCubrey, J.A.10
-
30
-
-
0033630308
-
Serine/threonine phosphorylation in cytokine signal transduction
-
McCubrey, J. A., May, W. S., Duronio, V., and Mufson, A. Serine/threonine phosphorylation in cytokine signal transduction. Leukemia, 14: 9-21, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 9-21
-
-
McCubrey, J.A.1
May, W.S.2
Duronio, V.3
Mufson, A.4
-
31
-
-
0033759376
-
Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells
-
Weinstein-Oppenheimer, C., Steelman, L. S., Algate, P. A., Blalock, W. L., Burrows, C., Hoyle, P. E., Lee, J. T., Moye, P. W., Shelton, J. G., Franklin, R., and McCubrey, J. A. Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells. Leukemia, 14: 1921-1938, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 1921-1938
-
-
Weinstein-Oppenheimer, C.1
Steelman, L.S.2
Algate, P.A.3
Blalock, W.L.4
Burrows, C.5
Hoyle, P.E.6
Lee, J.T.7
Moye, P.W.8
Shelton, J.G.9
Franklin, R.10
McCubrey, J.A.11
-
32
-
-
0035224494
-
Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells
-
McCubrey, J. A., Lee, J. T., Steelman, L. S., Blalock, W. L., Moye, P. W., Chang, F., Pearce, M., Shelton, J. G., White, M. K., Franklin, R. A., and Pohnert, S. C. Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells. Cancer Detect. Prev., 25: 375-393, 2001.
-
(2001)
Cancer Detect. Prev.
, vol.25
, pp. 375-393
-
-
McCubrey, J.A.1
Lee, J.T.2
Steelman, L.S.3
Blalock, W.L.4
Moye, P.W.5
Chang, F.6
Pearce, M.7
Shelton, J.G.8
White, M.K.9
Franklin, R.A.10
Pohnert, S.C.11
-
33
-
-
0027221138
-
A signal transduction pathway for activation of the mdr1 promoter involves the proto-oncogene c-raf kinase
-
Cornwell, M. M., and Smith, D. E. A signal transduction pathway for activation of the mdr1 promoter involves the proto-oncogene c-raf kinase. J. Biol. Chem., 268: 15347-15350, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15347-15350
-
-
Cornwell, M.M.1
Smith, D.E.2
-
34
-
-
0030048861
-
Effect of the activated Raf protein kinase on the human multidrug resistance 1 (MDR1) gene promoter
-
Kim, S-H., Lee, S-H., Kwak, N-H., Kang, C-D., and Chung, B-S. Effect of the activated Raf protein kinase on the human multidrug resistance 1 (MDR1) gene promoter. Cancer Lett., 98: 199-205, 1996.
-
(1996)
Cancer Lett.
, vol.98
, pp. 199-205
-
-
Kim, S.-H.1
Lee, S.-H.2
Kwak, N.-H.3
Kang, C.-D.4
Chung, B.-S.5
-
35
-
-
0031949369
-
High Raf-1 kinase activity protects human tumor cells against paclitaxel-induced cytotoxicity
-
Rasouli-Nia, A., Liu, D., Perdue, S., and Britten, R. A. High Raf-1 kinase activity protects human tumor cells against paclitaxel-induced cytotoxicity. Clin. Cancer Res., 4: 1111-1116, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1111-1116
-
-
Rasouli-Nia, A.1
Liu, D.2
Perdue, S.3
Britten, R.A.4
-
36
-
-
0034123442
-
Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells
-
Blalock, W. L., Moye, P. W., Chang, F., Pearce, M., Steelman, L. S., McMahon, M., and McCubrey, J. A. Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells. Leukemia, 14: 1080-1096, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 1080-1096
-
-
Blalock, W.L.1
Moye, P.W.2
Chang, F.3
Pearce, M.4
Steelman, L.S.5
McMahon, M.6
McCubrey, J.A.7
-
37
-
-
0034120633
-
Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells
-
Moye, P. W., Blalock, W. L., Hoyle, P. E., Chang, F., Franklin, R. A., Weinstein-Oppenheimer, C., Pearce, M., Steelman, L., McMahon, M., and McCubrey, J. A. Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells. Leukemia, 14: 1060-1079, 2000.
-
(2000)
Leukemia
, vol.14
, pp. 1060-1079
-
-
Moye, P.W.1
Blalock, W.L.2
Hoyle, P.E.3
Chang, F.4
Franklin, R.A.5
Weinstein-Oppenheimer, C.6
Pearce, M.7
Steelman, L.8
McMahon, M.9
McCubrey, J.A.10
-
38
-
-
0034652115
-
Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases
-
Deng, X., Ruvolo, P., Carr, B., and May, W. S., Jr. Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases. Proc. Natl. Acad. Sci. USA, 97: 1578-1583, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1578-1583
-
-
Deng, X.1
Ruvolo, P.2
Carr, B.3
May W.S., Jr.4
-
39
-
-
0024519944
-
Abrogation of factor-dependence in two IL-3-dependent cell lines can occur by two distinct mechanisms
-
McCubrey, J., Holland, G., McKearn, J., and Risser, R. Abrogation of factor-dependence in two IL-3-dependent cell lines can occur by two distinct mechanisms. Oncogene Res., 4: 97-109, 1989.
-
(1989)
Oncogene Res.
, vol.4
, pp. 97-109
-
-
McCubrey, J.1
Holland, G.2
McKearn, J.3
Risser, R.4
-
40
-
-
0027383001
-
Retroviral infection can abrogate the factor-dependency of hematopoietic cells by autocrine and non-autocrine mechanisms depending on the presence of a functional viral oncogene
-
McCubrey, J. A., Smith, S. R., Algate, P. A., DeVente, J. E., White, M. K., and Steelman, L. S. Retroviral infection can abrogate the factor-dependency of hematopoietic cells by autocrine and non-autocrine mechanisms depending on the presence of a functional viral oncogene. Oncogene, 8: 2905-2915, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 2905-2915
-
-
McCubrey, J.A.1
Smith, S.R.2
Algate, P.A.3
DeVente, J.E.4
White, M.K.5
Steelman, L.S.6
-
41
-
-
0030005128
-
Oncogenic effects of overexpression of the interleukin-3 receptor on hematopoietic cells
-
Steelman, L. S., Algate, P. A., Blalock, W. L., Wang, X-Y., Prevost, K. D., Hoyle, P. E., and McCubrey, J. A. Oncogenic effects of overexpression of the interleukin-3 receptor on hematopoietic cells. Leukemia, 10: 528-542, 1996.
-
(1996)
Leukemia
, vol.10
, pp. 528-542
-
-
Steelman, L.S.1
Algate, P.A.2
Blalock, W.L.3
Wang, X.-Y.4
Prevost, K.D.5
Hoyle, P.E.6
McCubrey, J.A.7
-
42
-
-
0029030083
-
Differential effects of viral and cellular oncogenes on the growth factor-dependency of hematopoietic cells
-
McCubrey, J. A., Steelman, L. S., Wang, X-Y., Algate, P. A., Hoyle, P. E., White, C., Davidian, E. W., Prevost, K. D., Robbins, P., Mylott, D., and White, M. K. Differential effects of viral and cellular oncogenes on the growth factor-dependency of hematopoietic cells. Int. J. Oncol., 7: 295-310, 1995.
-
(1995)
Int. J. Oncol.
, vol.7
, pp. 295-310
-
-
McCubrey, J.A.1
Steelman, L.S.2
Wang, X.-Y.3
Algate, P.A.4
Hoyle, P.E.5
White, C.6
Davidian, E.W.7
Prevost, K.D.8
Robbins, P.9
Mylott, D.10
White, M.K.11
-
43
-
-
0025255538
-
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
-
Nuñez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., and Korsmeyer, S. J. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol., 144: 3602-3610, 1990.
-
(1990)
J. Immunol.
, vol.144
, pp. 3602-3610
-
-
Nuñez, G.1
London, L.2
Hockenbery, D.3
Alexander, M.4
McKearn, J.P.5
Korsmeyer, S.J.6
-
44
-
-
0027385030
-
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase
-
Samuels, M. L., Weber, M. J., Bishop, J. M., and McMahon, M. Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase. Mol. Cell. Biol., 13: 6241-6252, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6241-6252
-
-
Samuels, M.L.1
Weber, M.J.2
Bishop, J.M.3
McMahon, M.4
-
46
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahon, J., Vistica, D., Warren, J. T., Bokesch, H., Kenney, S., and Boyd, M. R. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. (Bethesda), 82: 1107-1112, 1990.
-
(1990)
J. Natl. Cancer Inst. (Bethesda)
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
47
-
-
0034808394
-
Role of the Raf signal transduction cascade in the in vitro resistance to the anticancer drug doxorubicin
-
Weinstein-Oppenheimer, C. R., Henríquez-Roldán, C. F., Davis, J. M., Navolanic, P. M., Saleh, O. A., Steelman, L. S., Franklin, R. A., Robinson, P. J., McMahon, M., and McCubrey, J. A. Role of the Raf signal transduction cascade in the in vitro resistance to the anticancer drug doxorubicin. Clin. Cancer Res., 7: 2898-2907, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2898-2907
-
-
Weinstein-Oppenheimer, C.R.1
Henríquez-Roldán, C.F.2
Davis, J.M.3
Navolanic, P.M.4
Saleh, O.A.5
Steelman, L.S.6
Franklin, R.A.7
Robinson, P.J.8
McMahon, M.9
McCubrey, J.A.10
-
48
-
-
12944277104
-
A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
-
Giannakakou, P., Gussio, R., Nogales, E., Downing, K. H., Zaharevitz, D., Bollbuck, B., Poy, G., Sackett, D., Nicolaou, K. C., and Fojo, T. A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proc. Natl. Acad. Sci. USA, 97: 2904-2909, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2904-2909
-
-
Giannakakou, P.1
Gussio, R.2
Nogales, E.3
Downing, K.H.4
Zaharevitz, D.5
Bollbuck, B.6
Poy, G.7
Sackett, D.8
Nicolaou, K.C.9
Fojo, T.10
-
49
-
-
0029913172
-
Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway
-
Blagosklonny, M. V., Schulte, T., Nguyen, P., Trepel, J., and Neckers, L. M. Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res., 56: 1851-1854, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 1851-1854
-
-
Blagosklonny, M.V.1
Schulte, T.2
Nguyen, P.3
Trepel, J.4
Neckers, L.M.5
-
50
-
-
0034988898
-
Unwinding the loop of Bcl-2 phosphorylation
-
Blagosklonny, M. V. Unwinding the loop of Bcl-2 phosphorylation. Leukemia, 15: 869-874, 2001.
-
(2001)
Leukemia
, vol.15
, pp. 869-874
-
-
Blagosklonny, M.V.1
-
51
-
-
0029810469
-
Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis
-
Wilson, B. E., Mochon, E., and Boxer, L. M. Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. Mol. Cell. Biol., 16: 5546-5556, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5546-5556
-
-
Wilson, B.E.1
Mochon, E.2
Boxer, L.M.3
-
52
-
-
0033600722
-
E-B Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein
-
Pugazhenthi, S., Miller, E., Sable, C., Young, P., Heidenreich, K. A., Boxer L. M., and Reusch, J. E-B. Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J. Biol. Chem., 274: 27529-27535, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27529-27535
-
-
Pugazhenthi, S.1
Miller, E.2
Sable, C.3
Young, P.4
Heidenreich, K.A.5
Boxer, L.M.6
Reusch, J.7
-
53
-
-
0034949195
-
CREB is one component of the binding complex of the Ces-2/E2A-HLF binding element and is an integral part of the interleukin-3 survival signal
-
Chen, W., Yu, Y-L., Lee, S-F., Chiang, Y-J., Chao, J-R., Huang, J-H., Chiong, J-H., Huang, C-J., Lai, M-Z., Yang-Yen, H-F., and Yen, J. J-Y. CREB is one component of the binding complex of the Ces-2/E2A-HLF binding element and is an integral part of the interleukin-3 survival signal. Mol. Cell. Biol., 21: 4636-4646, 2001.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4636-4646
-
-
Chen, W.1
Yu, Y.-L.2
Lee, S.-F.3
Chiang, Y.-J.4
Chao, J.-R.5
Huang, J.-H.6
Chiong, J.-H.7
Huang, C.-J.8
Lai, M.-Z.9
Yang-Yen, H.-F.10
Yen, J.J.-Y.11
-
54
-
-
0034646644
-
Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein
-
Pugazhenthi, S., Nesterova, A., Sable, C., Heidenreich, K. A., Boxer, L. M., Heasley, L. E., and Reusch, J. E-B. Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. J. Biol. Chem., 275: 10761-10766, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10761-10766
-
-
Pugazhenthi, S.1
Nesterova, A.2
Sable, C.3
Heidenreich, K.A.4
Boxer, L.M.5
Heasley, L.E.6
Reusch, J.E.-B.7
|