Multidrug-resistant bacteria: Overcoming antibiotic permeability barriers of Gram-negative bacteria

Annals of Medicine

Volumn 33, Issue 3, 2001, Pages 167-171

  Savage, P B ^a  

^a Brigham Young University   (United States)

Author keywords

Drug resistant bacteria; Gram negative bacteria; Outer membrane; Permeabilizers

Indexed keywords

ERYTHROMYCIN; FUSIDIC ACID; NOVOBIOCIN; POLYMYXIN B; RIFAMPICIN;

ANTIBIOTIC RESISTANCE; BACTERIAL OUTER MEMBRANE; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG STRUCTURE; GRAM NEGATIVE BACTERIUM; MEMBRANE PERMEABILITY; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0035011244     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853890109002073     Document Type: Review

References (31)

1. Agents that increase the permeability of the outer membrane
2. Molecular basis of bacterial outer membrane permeability
3. Alterations in outer membrane permeability
4. Version 2000: The new betalactamases of Gram-negative bacteria at the dawn of the new millennium
5. Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia
6. Factors that predict preexisting colonization with antibiotic-resistant Gram-negative bacilli in patients admitted to a pediatric intensive care unit
7. Antibiotic-resistant Gram-negative bacteria in a virtually closed water reticulation system
8. The barrier function of the gram-negative envelope
9. Use of the fluorescent probe 1-N-phenylnaphthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa
10. Antimicrobial combinations
11. Sensitization of Gram-negative bacteria to antibiotics and complement by a nontoxic oligopeptide
12. Polymyxin B octa-peptide and polymyxin B heptapeptide are potent outer membrane permeability-increasing agents
13. In-vitro activity of colistin and rifampicin against multidrug-resistant strains of Acineto-bacter baumannii
14. Targeting lipopolysaccharides by the nontoxic polymyxin B nonapeptide sensitizes resistant Escherichia coli to the bactericidal effect of human neutrophils
15. Antibacterial synergism of polymyxin B nonapeptide and hydrophobic antibiotics in experimental Gram-negative infections in mice
16. Peptide antibiotics
17. Diversity of antimicrobial peptides and their mechanisms of action
18. In-vitro activity of cationic peptides alone and in combination with clinically used antimicrobial agents against Pseudomonas aeruginosa
19. In-vitro activities of membrane-active peptides alone and in combination with clinically used antimicrobial agents against Stenotrophomonas maltophilia
20. Biological properties of structurally related alpha-helical cationic antimicrobial peptides
21. Group of peptides that act synergistically with hydrophobic antibiotics against Gram-negative enteric bacteria
22. Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers
23. Antimicrobial activities of squalamine mimics
24. Antimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives
25. Squalamine: An aminosterol antibiotic from the shark
26. Cholic acid derivatives: Novel antimicrobials
27. Design and synthesis of potent sensitizers of Gram-negative bacteria based on a cholic acid scaffolding
28. Activities of cholic-acid derived antimicrobial agents against multidrug-resistant bacteria
29. Molecular basis for membrane selectivity of an antimicrobial peptide, magainin 2
30. Therapeutic potential of cationic peptides