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Volumn 17, Issue 2, 2003, Pages 442-450

IL-4 and interferon gamma regulate expression of inducible nitric oxide synthase in chronic lymphocytic leukemia cells

Author keywords

B lymphocytes; Chronic lymphocytic leukemia; Cytokines; Human; Nitric oxide

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; MESSENGER RNA; NITRATE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE;

EID: 0037330647     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402783     Document Type: Article
Times cited : (40)

References (71)
  • 1
    • 0032941221 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia: A bird of a different feather
    • Caligaris-Cappio F, Hamblin TJ. B-cell chronic lymphocytic leukemia: a bird of a different feather. J Clin Oncol 1999; 17: 399-408.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 399-408
    • Caligaris-Cappio, F.1    Hamblin, T.J.2
  • 3
    • 0024556599 scopus 로고
    • Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro
    • Collins RJ, Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JF. Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro. Br J Haematol 1989; 71: 343-350.
    • (1989) Br. J. Haematol. , vol.71 , pp. 343-350
    • Collins, R.J.1    Verschuer, L.A.2    Harmon, B.V.3    Prentice, R.L.4    Pope, J.H.5    Kerr, J.F.6
  • 4
    • 0029925659 scopus 로고    scopus 로고
    • Modulation of apoptosis with cytokines in B-cell chronic lymphocytic leukaemia
    • Mainou-Fowler T, Prentice AG. Modulation of apoptosis with cytokines in B-cell chronic lymphocytic leukaemia. Leuk Lymphoma 1996; 21: 369-377.
    • (1996) Leuk. Lymphoma. , vol.21 , pp. 369-377
    • Mainou-Fowler, T.1    Prentice, A.G.2
  • 5
    • 0029930173 scopus 로고    scopus 로고
    • Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion
    • Francia di Celle P, Mariani S, Riera L, Stacchini A, Reato G, Foa R. Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion. Blood 1996; 87: 4382-4389.
    • (1996) Blood , vol.87 , pp. 4382-4389
    • Francia di Celle, P.1    Mariani, S.2    Riera, L.3    Stacchini, A.4    Reato, G.5    Foa, R.6
  • 7
    • 0030893716 scopus 로고    scopus 로고
    • CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocytic leukemia B cells from apoptosis induced by anti-IgM
    • Osorio LM, De Santiago A, Aguilar-Santelises M, Mellstedt H, Jondal M. CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocytic leukemia B cells from apoptosis induced by anti-IgM. Blood 1997; 89: 2833-2841.
    • (1997) Blood , vol.89 , pp. 2833-2841
    • Osorio, L.M.1    De Santiago, A.2    Aguilar-Santelises, M.3    Mellstedt, H.4    Jondal, M.5
  • 8
    • 0027379859 scopus 로고
    • Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukaemia cells in vitro
    • Panayiotidis P, Ganeshaguru K, Jabbar SA, Hoffbrand AV. Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukaemia cells in vitro. Br J Haematol 1993; 85: 439-445.
    • (1993) Br. J. Haematol. , vol.85 , pp. 439-445
    • Panayiotidis, P.1    Ganeshaguru, K.2    Jabbar, S.A.3    Hoffbrand, A.V.4
  • 9
    • 0026754538 scopus 로고
    • Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression
    • Dancescu M, Rubio-Trujillo M, Biron G, Bron D, Delespesse G, Sarfati M. Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression. J Exp Med 1992; 176: 1319-1326.
    • (1992) J. Exp. Med. , vol.176 , pp. 1319-1326
    • Dancescu, M.1    Rubio-Trujillo, M.2    Biron, G.3    Bron, D.4    Delespesse, G.5    Sarfati, M.6
  • 10
    • 0028105132 scopus 로고
    • Interferon-alpha up-regulates bcl-2 expression and protects B-CLL cells from apoptosis in vitro and in vivo
    • Jewell AP, Worman CP, Lydyard PM, Yong KL, Giles FJ, Goldstone AH. Interferon-alpha up-regulates bcl-2 expression and protects B-CLL cells from apoptosis in vitro and in vivo. Br J Haematol 1994; 88: 268-274.
    • (1994) Br. J. Haematol. , vol.88 , pp. 268-274
    • Jewell, A.P.1    Worman, C.P.2    Lydyard, P.M.3    Yong, K.L.4    Giles, F.J.5    Goldstone, A.H.6
  • 11
    • 0028174176 scopus 로고
    • Alpha-interferon (alpha-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro
    • Panayiotidis P, Ganeshaguru K, Jabbar SA, Hoffbrand AV. Alpha-interferon (alpha-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro. Br J Haematol 1994; 86: 169-173.
    • (1994) Br. J. Haematol. , vol.86 , pp. 169-173
    • Panayiotidis, P.1    Ganeshaguru, K.2    Jabbar, S.A.3    Hoffbrand, A.V.4
  • 12
    • 0030048565 scopus 로고    scopus 로고
    • Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
    • Panayiotidis P, Jones D, Ganeshaguru K, Foroni L, Hoffbrand AV. Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br J Haematol 1996; 92: 97-103.
    • (1996) Br. J. Haematol. , vol.92 , pp. 97-103
    • Panayiotidis, P.1    Jones, D.2    Ganeshaguru, K.3    Foroni, L.4    Hoffbrand, A.V.5
  • 13
    • 0029937459 scopus 로고    scopus 로고
    • Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia
    • Reittie JE, Yong KL, Panayiotidis P, Hoffbrand AV. Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia. Leuk Lymphoma 1996; 22: 83-90.
    • (1996) Leuk. Lymphoma , vol.22 , pp. 83-90
    • Reittie, J.E.1    Yong, K.L.2    Panayiotidis, P.3    Hoffbrand, A.V.4
  • 15
    • 0029881832 scopus 로고    scopus 로고
    • Expression of granulocyte colony-stimulating factor and granulocyte colony-stimulating factor receptor genes in partially overlapping monoclonal B-cell populations from chronic lymphocytic leukemia patients
    • Corcione A, Corrias MV, Daniele S, Zupo S, Spriano M, Pistoia V. Expression of granulocyte colony-stimulating factor and granulocyte colony-stimulating factor receptor genes in partially overlapping monoclonal B-cell populations from chronic lymphocytic leukemia patients. Blood 1996; 87: 2861-2869.
    • (1996) Blood , vol.87 , pp. 2861-2869
    • Corcione, A.1    Corrias, M.V.2    Daniele, S.3    Zupo, S.4    Spriano, M.5    Pistoia, V.6
  • 17
    • 0032147236 scopus 로고    scopus 로고
    • B-Cell Chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity
    • Zhao HX, Dugas N, Mathiot C, Delmer A, Dugas B, Sigaux F, Kolb JP. B-Cell Chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity. Blood 1998; 92: 1031-1043.
    • (1998) Blood , vol.92 , pp. 1031-1043
    • Zhao, H.X.1    Dugas, N.2    Mathiot, C.3    Delmer, A.4    Dugas, B.5    Sigaux, F.6    Kolb, J.P.7
  • 18
    • 0032573853 scopus 로고    scopus 로고
    • To die or not to die: An overview of apoptosis and its role in disease
    • Hetts SW. To die or not to die: an overview of apoptosis and its role in disease. JAMA 1998; 279: 300-307.
    • (1998) JAMA , vol.279 , pp. 300-307
    • Hetts, S.W.1
  • 19
    • 0029897734 scopus 로고    scopus 로고
    • Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX
    • McConkey DJ, Chandra J, Wright S, Plunkett W, McDonnell TJ, Reed JC, Keating M. Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX. J Immunol 1996; 156: 2624-2630.
    • (1996) J. Immunol. , vol.156 , pp. 2624-2630
    • McConkey, D.J.1    Chandra, J.2    Wright, S.3    Plunkett, W.4    McDonnell, T.J.5    Reed, J.C.6    Keating, M.7
  • 20
    • 0030752756 scopus 로고    scopus 로고
    • Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance
    • Pepper C, Hoy T, Bentley DP. Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance. Br J Cancer 1997; 76: 935-938.
    • (1997) Br. J. Cancer , vol.76 , pp. 935-938
    • Pepper, C.1    Hoy, T.2    Bentley, D.P.3
  • 21
    • 0030905543 scopus 로고    scopus 로고
    • Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells
    • Bellosillo B, Dalmau M, Colomer D, Gil J. Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells. Blood 1997; 89: 3378-3384.
    • (1997) Blood , vol.89 , pp. 3378-3384
    • Bellosillo, B.1    Dalmau, M.2    Colomer, D.3    Gil, J.4
  • 22
    • 0028917191 scopus 로고
    • Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels
    • Genaro AM, Hortelano S, Alvarez A, Martinez C, Bosca L. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J Clin Invest 1995; 95: 1884-1890.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1884-1890
    • Genaro, A.M.1    Hortelano, S.2    Alvarez, A.3    Martinez, C.4    Bosca, L.5
  • 23
    • 0031037180 scopus 로고    scopus 로고
    • Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases
    • Dimmeler S, Haendeler J, Nehls M, Zeiher AM. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases. J Exp Med 1997; 185: 601-607.
    • (1997) J. Exp. Med. , vol.185 , pp. 601-607
    • Dimmeler, S.1    Haendeler, J.2    Nehls, M.3    Zeiher, A.M.4
  • 24
    • 0031576527 scopus 로고    scopus 로고
    • Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation
    • Li J, Billiar TR, Talanian RV, Kim YM. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem Biophys Res Commun 1997; 240: 419-424.
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 419-424
    • Li, J.1    Billiar, T.R.2    Talanian, R.V.3    Kim, Y.M.4
  • 25
    • 0031577534 scopus 로고    scopus 로고
    • Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide
    • Mohr S, Zech B, Lapetina EG, Brune B. Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide. Biochem Biophys Res Commun 1997; 238: 387-391.
    • (1997) Biochem. Biophys. Res. Commun. , vol.238 , pp. 387-391
    • Mohr, S.1    Zech, B.2    Lapetina, E.G.3    Brune, B.4
  • 27
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-2012.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 28
    • 0027975453 scopus 로고
    • Nitric oxide: A physiologic messenger molecule
    • Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 1994; 63: 175-195.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 175-195
    • Bredt, D.S.1    Snyder, S.H.2
  • 29
    • 0031784643 scopus 로고    scopus 로고
    • Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: A review
    • Weinberg JB. Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review. Mol Med 1998; 4: 557-591.
    • (1998) Mol. Med. , vol.4 , pp. 557-591
    • Weinberg, J.B.1
  • 30
    • 0001637870 scopus 로고
    • Permanent cell line expressing human factor VIII-related antigen established by hybridization
    • Edgell CJ, McDonald CC, Graham JB. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc Natl Acad Sci USA 1983; 80: 3734-3737.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 3734-3737
    • Edgell, C.J.1    McDonald, C.C.2    Graham, J.B.3
  • 31
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest - Suppl 1968; 97: 77-89.
    • (1968) Scand. J. Clin. Lab. Invest. , vol.97 , Issue.SUPPL. , pp. 77-89
    • Boyum, A.1
  • 32
    • 0034886752 scopus 로고    scopus 로고
    • Use of serum-free media to minimize apoptosis of chronic lymphocytic leukemia cells during in vitro culture
    • Levesque MC, O'Loughlin CW, Weinberg JB. Use of serum-free media to minimize apoptosis of chronic lymphocytic leukemia cells during in vitro culture. Leukemia 2001; 15: 1305-1307.
    • (2001) Leukemia , vol.15 , pp. 1305-1307
    • Levesque, M.C.1    O'Loughlin, C.W.2    Weinberg, J.B.3
  • 33
    • 0029133539 scopus 로고
    • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages
    • Weinberg JB, Misukonis MA, Shami PJ, Mason SN, Sauls DL, Dittman WA, Wood ER, Smith GK, McDonald B, Bachus KE et al. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood 1995; 86: 1184-1195.
    • (1995) Blood , vol.86 , pp. 1184-1195
    • Weinberg, J.B.1    Misukonis, M.A.2    Shami, P.J.3    Mason, S.N.4    Sauls, D.L.5    Dittman, W.A.6    Wood, E.R.7    Smith, G.K.8    McDonald, B.9    Bachus, K.E.10
  • 34
    • 0027372580 scopus 로고
    • Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line
    • Sherman PA, Laubach VE, Reep BR, Wood ER. Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line. Biochemistry 1993; 32: 11600-11605.
    • (1993) Biochemistry , vol.32 , pp. 11600-11605
    • Sherman, P.A.1    Laubach, V.E.2    Reep, B.R.3    Wood, E.R.4
  • 35
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 37
    • 0026033780 scopus 로고
    • Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine
    • Granger DL, Hibbs JB Jr, Broadnax LM. Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine. J Immunol 1991; 146: 1294-1302.
    • (1991) J. Immunol. , vol.146 , pp. 1294-1302
    • Granger, D.L.1    Hibbs J.B., Jr.2    Broadnax, L.M.3
  • 38
    • 0028658374 scopus 로고
    • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
    • Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 1994; 79: 1137-1146.
    • (1994) Cell , vol.79 , pp. 1137-1146
    • Mannick, J.B.1    Asano, K.2    Izumi, K.3    Kieff, E.4    Stamler, J.S.5
  • 39
    • 0029990083 scopus 로고    scopus 로고
    • Nitric oxide synthase: Expression of the endothelial, Ca2+/calmodulin-dependent isoform in human B and T lymphocytes
    • Reiling N, Kroncke R, Ulmer AJ, Gerdes J, Flad HD, Hauschildt S. Nitric oxide synthase: expression of the endothelial, Ca2+/calmodulin-dependent isoform in human B and T lymphocytes. Eur J Immunol 1996; 26: 511-516.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 511-516
    • Reiling, N.1    Kroncke, R.2    Ulmer, A.J.3    Gerdes, J.4    Flad, H.D.5    Hauschildt, S.6
  • 40
    • 0032533159 scopus 로고    scopus 로고
    • Arginine metabolism: Nitric oxide and beyond
    • Wu G, Morris SM Jr. Arginine metabolism: nitric oxide and beyond. Biochem J 1998; 336: 1-17.
    • (1998) Biochem. J. , vol.336 , pp. 1-17
    • Wu, G.1    Morris S.M., Jr.2
  • 43
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999; 94: 1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 46
    • 0022360766 scopus 로고
    • Y+- and L-system amino acid transport in normal and chronic lymphocytic leukemia lymphocytes: Photoinhibition by fluoronitrophenylazide
    • Segel GB, Tometsko AM, Lichtman MA. Y+- and L-system amino acid transport in normal and chronic lymphocytic leukemia lymphocytes: photoinhibition by fluoronitrophenylazide. Arch Biochem Biophys 1985; 242: 347-354.
    • (1985) Arch. Biochem. Biophys. , vol.242 , pp. 347-354
    • Segel, G.B.1    Tometsko, A.M.2    Lichtman, M.A.3
  • 47
    • 0031452440 scopus 로고    scopus 로고
    • A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the 'arginine paradox'
    • McDonald KK, Zharikov S, Block ER, Kilberg MS. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the 'arginine paradox'. J Biol Chem 1997; 272: 31213-31216.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31213-31216
    • McDonald, K.K.1    Zharikov, S.2    Block, E.R.3    Kilberg, M.S.4
  • 48
    • 0035708575 scopus 로고    scopus 로고
    • Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase
    • Flam BR, Hartmann PJ, Harrell-Booth M, Solomonson LP, Eichler DC. Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase. Nitric Oxide 2001; 5: 187-197.
    • (2001) Nitric Oxide , vol.5 , pp. 187-197
    • Flam, B.R.1    Hartmann, P.J.2    Harrell-Booth, M.3    Solomonson, L.P.4    Eichler, D.C.5
  • 49
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S, Pou WS, Bredt DS, Snyder SH, Rosen GM. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem 1992; 267: 24173-24176.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 50
    • 0029900905 scopus 로고    scopus 로고
    • Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury
    • Xia Y, Dawson VL, Dawson TM, Snyder SH, Zweier JL. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proc Natl Acad Sci USA 1996; 93: 6770-6774.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6770-6774
    • Xia, Y.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4    Zweier, J.L.5
  • 51
    • 0029793534 scopus 로고    scopus 로고
    • Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport
    • Simmons WW, Ungureanu-Longrois D, Smith GK, Smith TW, Kelly RA. Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport. J Biol Chem 1996; 271: 23928-23937.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23928-23937
    • Simmons, W.W.1    Ungureanu-Longrois, D.2    Smith, G.K.3    Smith, T.W.4    Kelly, R.A.5
  • 52
    • 0035929149 scopus 로고    scopus 로고
    • Nitrosylation: The prototypic redox-based signaling mechanism
    • Stamler JS, Lamas S, Fang FC. Nitrosylation: the prototypic redox-based signaling mechanism. Cell 2001; 106: 675-683.
    • (2001) Cell , vol.106 , pp. 675-683
    • Stamler, J.S.1    Lamas, S.2    Fang, F.C.3
  • 53
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxy-nitrite: The good, the bad, and ugly
    • Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxy-nitrite: the good, the bad, and ugly. Amer J Physiol 1996; 271: C1424-C1437.
    • (1996) Amer. J. Physiol. , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 54
    • 0030865879 scopus 로고    scopus 로고
    • Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators
    • [published erratum appears in J Clin Invest 1997 Sep 1;100(5):1322]
    • Guo FH, Uetani K, Haque SJ, Williams BR, Dweik RA, Thunnissen FB, Calhoun W, Erzurum SC. Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators [published erratum appears in J Clin Invest 1997 Sep 1;100(5):1322]. J Clin Invest 1997; 100: 829-838.
    • (1997) J. Clin. Invest. , vol.100 , pp. 829-838
    • Guo, F.H.1    Uetani, K.2    Haque, S.J.3    Williams, B.R.4    Dweik, R.A.5    Thunnissen, F.B.6    Calhoun, W.7    Erzurum, S.C.8
  • 55
    • 0034054449 scopus 로고    scopus 로고
    • Molecular mechanisms regulating iNOS expression in various cell types
    • Rao KMK. Molecular mechanisms regulating iNOS expression in various cell types. J Toxicol Environ Health, B 2000; 3: 27-58.
    • (2000) J. Toxicol. Environ. Health, B , vol.3 , pp. 27-58
    • Rao, K.M.K.1
  • 56
    • 0027991932 scopus 로고
    • Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon
    • Sands WA, Bulut V, Severn A, Xu D, Liew FY. Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. Eur J Immunol 1994; 24: 2345-2350.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2345-2350
    • Sands, W.A.1    Bulut, V.2    Severn, A.3    Xu, D.4    Liew, F.Y.5
  • 57
    • 0028360727 scopus 로고
    • Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway
    • Kolb JP, Paul-Eugene N, Damais C, Yamaoka K, Drapier JC, Dugas B. Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway. J Biol Chem 1994; 269: 9811-9816.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9811-9816
    • Kolb, J.P.1    Paul-Eugene, N.2    Damais, C.3    Yamaoka, K.4    Drapier, J.C.5    Dugas, B.6
  • 58
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides H, Reich NC. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 1993; 262: 1265-1267.
    • (1993) Science , vol.262 , pp. 1265-1267
    • Kotanides, H.1    Reich, N.C.2
  • 59
    • 0029093023 scopus 로고
    • Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of Janus kinase 3 and interleukin-4 Stat
    • Fenghao X, Saxon A, Nguyen A, Ke Z, Diaz-Sanchez D, Nel A. Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of Janus kinase 3 and interleukin-4 Stat. J Clin Invest 1995; 96: 907-914.
    • (1995) J. Clin. Invest. , vol.96 , pp. 907-914
    • Fenghao, X.1    Saxon, A.2    Nguyen, A.3    Ke, Z.4    Diaz-Sanchez, D.5    Nel, A.6
  • 60
    • 0031436969 scopus 로고    scopus 로고
    • B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues
    • Frank DA, Mahajan S, Ritz J. B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues. J Clin Invest 1997; 100: 3140-3148.
    • (1997) J. Clin. Invest. , vol.100 , pp. 3140-3148
    • Frank, D.A.1    Mahajan, S.2    Ritz, J.3
  • 62
    • 0025764757 scopus 로고
    • Interleukin-4: A prototypic immunoregulatory lymphokine
    • Paul WE. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 1991; 77: 1859-1870.
    • (1991) Blood , vol.77 , pp. 1859-1870
    • Paul, W.E.1
  • 63
    • 0030916553 scopus 로고    scopus 로고
    • Cytokines involved in B-cell differentiation and their sites of action
    • Takatsu K. Cytokines involved in B-cell differentiation and their sites of action. Proc Soc Exp Biol Med 1997; 215: 121-133.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.215 , pp. 121-133
    • Takatsu, K.1
  • 65
    • 0032536832 scopus 로고    scopus 로고
    • Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded
    • Foote LC, Marshak-Rothstein A, Rothstein TL. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded. J Exp Med 1998; 187: 847-853.
    • (1998) J. Exp. Med. , vol.187 , pp. 847-853
    • Foote, L.C.1    Marshak-Rothstein, A.2    Rothstein, T.L.3
  • 66
    • 0034084526 scopus 로고    scopus 로고
    • Disruption of the IFN-gamma cytokine network in chronic lymphocytic leukemia contributes to resistance of leukemic B cells to apoptosis
    • Zaki M, Douglas R, Patten N, Bachinsky M, Lamb R, Nowell P, Moore J. Disruption of the IFN-gamma cytokine network in chronic lymphocytic leukemia contributes to resistance of leukemic B cells to apoptosis. Leukemia Res 2000; 24: 611-621.
    • (2000) Leukemia Res. , vol.24 , pp. 611-621
    • Zaki, M.1    Douglas, R.2    Patten, N.3    Bachinsky, M.4    Lamb, R.5    Nowell, P.6    Moore, J.7
  • 67
    • 0031044585 scopus 로고    scopus 로고
    • Analysis of blood T-cell cytokine expression in B-chronic lymphocytic leukaemia: Evidence for increased levels of cytoplasmic IL-4 in resting and activated CD8 T cells
    • Mu X, Kay NE, Gosland MP, Jennings CD. Analysis of blood T-cell cytokine expression in B-chronic lymphocytic leukaemia: evidence for increased levels of cytoplasmic IL-4 in resting and activated CD8 T cells. Br J Haematol 1997; 96: 733-735.
    • (1997) Br. J. Haematol. , vol.96 , pp. 733-735
    • Mu, X.1    Kay, N.E.2    Gosland, M.P.3    Jennings, C.D.4
  • 68
    • 0035106335 scopus 로고    scopus 로고
    • Interleukin 4 content in chronic lymphocytic leukaemia (CLL) B cells and blood CD8+ T cells from B-CLL patients: Impact on clonal B-cell apoptosis
    • Kay NE, Han L, Bone N, Williams G. Interleukin 4 content in chronic lymphocytic leukaemia (CLL) B cells and blood CD8+ T cells from B-CLL patients: impact on clonal B-cell apoptosis. Br J Haematol 2001; 112: 760-767.
    • (2001) Br. J. Haematol. , vol.112 , pp. 760-767
    • Kay, N.E.1    Han, L.2    Bone, N.3    Williams, G.4
  • 69
    • 0035137920 scopus 로고    scopus 로고
    • The levels of TNF alpha, IL4 and IL10 production by T-cells in B-cell chronic lymphocytic leukaemia (B-CLL)
    • Mainou-Fowler T, Miller S, Proctor SJ, Dickinson AM. The levels of TNF alpha, IL4 and IL10 production by T-cells in B-cell chronic lymphocytic leukaemia (B-CLL). Leukemia Res 2001; 25: 157-163.
    • (2001) Leukemia Res. , vol.25 , pp. 157-163
    • Mainou-Fowler, T.1    Miller, S.2    Proctor, S.J.3    Dickinson, A.M.4


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