Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats

Hepatology

Volumn 29, Issue 6, 1999, Pages 1833-1839

  Vos, T A ^a   Ros, J E ^a   Havinga, R ^a   Moshage, H ^a   Kuipers, F ^a   Jansen, P L M ^a   Muller, M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BILE SALT; BILIRUBIN; CHOLESTEROL; GLUTATHIONE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE FLOW; BILE SECRETION; CELL LEVEL; CONTROLLED STUDY; FLOW RATE; LIPID TRANSPORT; LIVER REGENERATION; LIVER RESECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RAT; REGULATORY MECHANISM;

EID: 0033036103     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290638     Document Type: Article

References (45)

1. 1 Müller M, Jansen PLM. The secretory function of the liver: new aspects of hepatobiliary transport. J Hepatol 1998 ; 28: 344–354. MEDLINE
2. 2 Müller M, Jansen PLM. Molecular aspects of hepatobiliary transport. Am J Physiol 1997 ; 272: G1285–G1303. MEDLINE
3. 3 Fausto N, Webber EM. Liver regeneration. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Shafritz DA, eds. The Liver: Biology and Pathobiology. New York: Raven. 1994 ; 1059–1084.
4. 4 Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997 ; 276: 60–66. MEDLINE
5. 5 Hoshino M, Hirano A, Hayakawa T, Kamiya Y, Ohiwa T, Tanaka A, Kumai T, et al. Comparative studies on bile flow and biliary lipid excretion after bile‐acid loading in normal and partially hepatectomized rats. Biochem J 1995 ; 305: 367–371. MEDLINE
6. 6 Fukano S, Saitoh Y, Uchida K, Akiyoshi T, Takeda K. Bile acid metabolism in partially hepatectomized rats. Steroids 1985 ; 45: 209–227. MEDLINE
7. 7 Monte MJ, El‐Mir MY, Sainz GR, Bravo P, Marin JJG. Bile acid secretion during synchronized rat liver regeneration. Biochim Biophys Acta 1997 ; 1362: 56–66. MEDLINE
8. 8 Uesugi T, Bognacki J, Levine WG. Biliary exretion of drugs in the rat during liver regeneration. Biochem Pharmacol 1976 ; 25: 1187–1193. MEDLINE
9. 9 Hagenbuch B, Stieger B, Foguet M, Lübbert H, Meier PJ. Functional expression cloning and characterization of the hepatocyte Na + /bile acid cotransport system. Proc Natl Acad Sci U S A 1991 ; 88: 10629–10633. MEDLINE
10. 10 Jacquemin E, Hagenbuch B, Stieger B, Wolkoff AW, Meier PJ. Expression cloning of a rat liver Na + ‐independent organic anion transporter. Proc Natl Acad Sci U S A 1994 ; 91: 133–137. MEDLINE
11. 11 Noé B, Hagenbuch B, Stieger B, Meier PJ. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci U S A 1997 ; 94: 10346–10350. MEDLINE
12. 12 Meier PJ, Eckhardt U, Schroeder A, Hagenbuch B, Stieger B. Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver. Hepatology 1997 ; 26: 1667–1677. MEDLINE
13. 13 Li L, Lee TK, Meier PJ, Ballatori N. Identification of glutathione as a driving force and leukotriene C as a substrate for oatp1, the hepatic sinusoidal organic anion solute transporter. J Biol Chem 1998 ; 273: 16184–16191.
14. 14 Gerloff T, Stieger B, Hagenbuch B, Madon J, Landmann L, Roth J, Hofmann AF, et al. The sister of P‐glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem 1998 ; 273: 10046–10050. MEDLINE
15. 15 Kool M, de Haas M, Scheffer GL, Scheper RJ, van Eijk MJT, Juijn JA, Baas F, et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance‐associated protein gene (MRP1), in human cancer cell lines. Cancer Res 1997 ; 57: 3537–3547. MEDLINE
16. 16 Hirohashi T, Suzuki H, Ito K, Ogawa K, Kume K, Shimizu T, Sugiyama Y. Hepatic expression of multidrug resistance‐associated protein‐like proteins maintained in Eisai hyperbilirubinemic rats. Mol Pharmacol 1998 ; 53: 1068–1075. MEDLINE
17. 17 Madon J, Hagenbuch B, Gerloff T, Landmann L, Meier PJ, Stieger B. Identification of a novel multidrug resistance‐associated protein (mrp6) at the lateral plasma membrane of rat hepatocytes [Abstract]. Hepatology 1998 ; 28: 400A.
18. 18 Green RM, Gollan JL, Hagenbuch B, Meier PJ, Beier DR. Regulation of hepatocyte bile salt transporters during hepatic regeneration. Am J Physiol 1997 ; 273: G621–G627. MEDLINE
19. 19 Nakatsukasa H, Silverman JA, Gant TW, Evarts RP, Thorgeirsson SS. Expression of multidrug resistance genes in rat liver during regeneration and after carbon tetrachloride intoxication. Hepatology 1993 ; 18: 1202–1207. MEDLINE
20. 20 Thorgeirsson SS, Huber BE, Sorrell S, Fojo A, Pastan I, Gottesman MM. Expression of the multidrug‐resistant gene in hepatocarcinogenesis and regenerating rat liver. Science 1987 ; 236: 1120–1122. MEDLINE
21. 21 Marino PA, Gottesman MM, Pastan I. Regulation of the multidrug resistance gene in regenerating rat liver. Cell Growth Differ 1990 ; 1: 57–62. MEDLINE
22. 22 Teeter LD, Estes M, Chan JY, Atassi H, Sell S, Becker FF, Kuo MT. Activation of distinct multidrug‐resistance (P‐glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis. Mol Carcinog 1993 ; 8: 67–73. MEDLINE
23. 23 Higgins GM, Anderson RM. Experimental pathology of the liver I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931 ; 12: 186–202.
24. 24 Moshage H, Casini A, Lieber CS. Acetaldehyde selectively stimulates collagen production in cultured rat liver fat‐storing cells but not in hepatocytes. Hepatology 1990 ; 12: 511–518. MEDLINE
25. 25 Koopen NR, Wolters H, Havinga R, Vonk RJ, Jansen PLM, Müller M, Kuipers F. Impaired activity of the bile canalicular organic anion transporter (mrp2/cmoat) is not the main cause of ethinylestradiol‐induced cholestasis in the rat. Hepatology 1998 ; 27: 537–545. MEDLINE
26. 26 Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2‐vinylpyridine. Anal Biochem 1980 ; 160: 207–212.
27. 27 Li YS, Hayakawa K, Hardy RR. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J Exp Med 1993 ; 178: 951–960. MEDLINE
28. 28 Vos TA, Hooiveld GJEJ, Koning H, Childs S, Meijer DKF, Moshage H, Jansen PLM, et al. Up‐regulation of the multidrug resistance genes, mrp1 and mdr1b, and down‐regulation of the organic anion transporter, mrp2, and the bile salt transporter, spgp, in endotoxemic rat liver. Hepatology 1998 ; 28: 1637–1644. MEDLINE
29. 29 Stieger B, Hagenbuch B, Landmann L, Höchli M, Schroeder A, Meier PJ. In situ localization of the hepatocytic Na + /taurocholate cotransporting polypeptide in rat liver. Gastroenterology 1994 ; 107: 1781–1787. MEDLINE
30. 30 Bergwerk AJ, Shi X, Ford AC, Kanai N, Jacquemin E, Burk RD, Bai S, et al. Immunologic distribution of an organic anion transport protein in rat liver and kidney. Am J Physiol 1996 ; 34: G231–G238.
31. 31 Reichel C, Gao B, Cattori V, Landmann L, Sugiyama Y, Stieger B, Hagenbuch B, et al. Heterogenous expression of the polyspecific organic anion transporter oatp2 in rat liver and its identification as a cyclic peptide transporter [Abstract]. Hepatology 1998 ; 28: 425A.
32. 32 Goldsworthy SM, Goldsworthy TL, Sprankle CS, Butterworth BE. Variation in expression of genes used for normalization of Northern blots after induction of cell proliferation. Cell Prolif 1993 ; 26: 511–517. MEDLINE
33. 33 Haber BA, Mohn KL, Diamond RH, Taub R. Induction patterns of 70 genes during nine days after hepatectomy define the temporal course of liver regeneration. J Clin Invest 1993 ; 91: 1319–1326. MEDLINE
34. 34 Tran‐Paterson R, Davin D, Krauss RD, Rado TA, Miller DM. Expression and regulation of the cystic fibrosis gene during rat liver regeneration. Am J Physiol 1992 ; 263: C55–C60. MEDLINE
35. 35 Paulusma CC, van Geer MA, Evers R, Heijn M, Ottenhoff R, Borst P, Oude Elferink RPJ. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low‐affinity transport of reduced glutathione. Biochem J 1999 ; 338: 393–401. MEDLINE
36. 36 Roelofsen H, Vos TA, Schippers IJ, Kuipers F, Koning H, Moshage H, Jansen PLM, et al. Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte‐derived cells. Gastroenterology 1997 ; 112: 511–521. MEDLINE
37. 37 Hagenbuch B, Meier PJ. Molecular cloning, chromosomal localization, and functional characterization of a human liver Na + /bile acid cotransporter. J Clin Invest 1994 ; 93: 1326–1331. MEDLINE
38. 38 Kullak‐Ublick G, Hagenbuch B, Stieger B, Wolkoff AW, Meier PJ. Functional characterization of the basolateral rat liver organic anion transporting polypeptide. Hepatology 1994 ; 20: 411–416. MEDLINE
39. 39 Huang ZZ, Li H, Cai J, Kuhlenkamp J, Kaplowitz N, Lu SC. Changes in glutathione homeostasis during liver regeneration in the rat. Hepatology 1998 ; 27: 147–153. MEDLINE
40. 40 Baumgartner U, Miyai K, Hardison WGM. Modulation of hepatic biotransformation and biliary excretion of bile acid by age and sinusoidal bile acid loading. Am J Physiol 1987 ; 252: G114–G119. MEDLINE
41. 41 Buscher HP, Schramm U, MacNelly S, Kurz G, Gerok W. The acinar location of the sodium‐independent and the sodium‐dependent component of taurocholate uptake. A histoautoradiographic study of rat liver. J Hepatol 1991 ; 13: 169–179. MEDLINE
42. 42 Groothuis GMM, Hardonk MJ, Keulemans KPT, Nieuwenhuis P, Meijer DKF. Autoradiographic and kinetic demonstration of acinar heterogeneity of taurocholate transport. Am J Physiol 1982 ; 243: G455–G462. MEDLINE
43. 43 Reichen J, Le M. Expansion of the bile acid pool changes the biliary transport characteristics of centrizonal hepatocytes. Experientia 1989 ; 45: 135–137. MEDLINE
44. 44 Baumgartner U, Sellinger M, Ruf G, Jehle L, Ihling C, Farthmann EH. Change of zonal bile acid processing after partial hepatectomy in the rat. J Hepatol 1995 ; 22: 474–480. MEDLINE
45. 45 Jedlitschky G, Leier I, Buchholz U, Hummel‐Eisenbeiss J, Burchell B, Keppler D. ATP‐dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem J 1997 ; 327: 305–310. MEDLINE