-
1
-
-
0027326663
-
Homeotic genes of Drosophila
-
Morata G. Homeotic genes of Drosophila. Curr Opin Genet Dev. 3:1993;606-614.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 606-614
-
-
Morata, G.1
-
2
-
-
0026504525
-
Homeobox genes and axial patterning
-
McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell. 68:1992;283-302.
-
(1992)
Cell
, vol.68
, pp. 283-302
-
-
McGinnis, W.1
Krumlauf, R.2
-
3
-
-
0028908369
-
Chromatin multiprotein complexes involved in the maintenance of transcription patterns
-
Orlando V, Paro R. Chromatin multiprotein complexes involved in the maintenance of transcription patterns. Curr Opin Genet Dev. 5:1995;174-179.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 174-179
-
-
Orlando, V.1
Paro, R.2
-
4
-
-
0029100039
-
Chromatin complexes regulating gene expression in Drosophila
-
Pirrotta V. Chromatin complexes regulating gene expression in Drosophila. Curr Opin Genet Dev. 5:1995;466-472.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 466-472
-
-
Pirrotta, V.1
-
5
-
-
0029065737
-
Locking in stable states of gene expression: Transcriptional control during Drosophila development
-
Simon J. Locking in stable states of gene expression: transcriptional control during Drosophila development. Curr Opin Cell Biol. 7:1995;376-385.
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 376-385
-
-
Simon, J.1
-
6
-
-
0029120270
-
The role of brahma and related proteins in transcription and development
-
Tamkun JW. The role of brahma and related proteins in transcription and development. Curr Opin Genet Dev. 5:1995;473-477.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 473-477
-
-
Tamkun, J.W.1
-
7
-
-
0029360439
-
Transcriptional silencing of homeotic genes in Drosophila
-
Bienz M, Müller J. Transcriptional silencing of homeotic genes in Drosophila. Bioessays. 17:1995;775-784.
-
(1995)
Bioessays
, vol.17
, pp. 775-784
-
-
Bienz, M.1
Müller, J.2
-
8
-
-
0030024356
-
Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression
-
of special interest. The accessibility of the bithorax complex to transcriptional activation by GAL4 and T7 RNA polymerase is assayed in Drosophila embryos carrying the appropriate heterologous binding sites inserted into the bithorax regulatory region. Whereas GAL4 activation is restricted to posterior segments where bithorax is normally active, T7 RNA polymerase is not inhibited by Polycomb-dependent repression and can transcribe from its target promoter in all segments of the embryo. Thus, the accessibility of PcG-silenced chromatin shows some specificity and not all proteins are excluded.
-
McCall K, Bender W. Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression. of special interest EMBO J. 15:1996;569-580 The accessibility of the bithorax complex to transcriptional activation by GAL4 and T7 RNA polymerase is assayed in Drosophila embryos carrying the appropriate heterologous binding sites inserted into the bithorax regulatory region. Whereas GAL4 activation is restricted to posterior segments where bithorax is normally active, T7 RNA polymerase is not inhibited by Polycomb-dependent repression and can transcribe from its target promoter in all segments of the embryo. Thus, the accessibility of PcG-silenced chromatin shows some specificity and not all proteins are excluded.
-
(1996)
EMBO J
, vol.15
, pp. 569-580
-
-
McCall, K.1
Bender, W.2
-
9
-
-
0025201233
-
Expression of a novel DNA-binding protein with zinc finger structure in various tumour cells
-
Tagawa M, Sakamoto T, Shigemoto K, Matsubara H, Tamura Y, Ito T, Nakamura I, Okitsu A, Imai K, Taniguchi M. Expression of a novel DNA-binding protein with zinc finger structure in various tumour cells. J Biol Chem. 265:1990;20021-20026.
-
(1990)
J Biol Chem
, vol.265
, pp. 20021-20026
-
-
Tagawa, M.1
Sakamoto, T.2
Shigemoto, K.3
Matsubara, H.4
Tamura, Y.5
Ito, T.6
Nakamura, I.7
Okitsu, A.8
Imai, K.9
Taniguchi, M.10
-
10
-
-
0025914005
-
Drosophila genes Posterior Sex Combs and Suppressor two of zeste encode proteins with homology to the murine bmi-1 oncogene
-
Brunk B, Martin E, Alder P. Drosophila genes Posterior Sex Combs and Suppressor two of zeste encode proteins with homology to the murine bmi-1 oncogene. Nature. 353:1991;351-353.
-
(1991)
Nature
, vol.353
, pp. 351-353
-
-
Brunk, B.1
Martin, E.2
Alder, P.3
-
11
-
-
0025773264
-
Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2
-
Van Lohuizen M, Frasch M, Wientjens E, Berns A. Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2. Nature. 353:1991;353-355.
-
(1991)
Nature
, vol.353
, pp. 353-355
-
-
Van Lohuizen, M.1
Frasch, M.2
Wientjens, E.3
Berns, A.4
-
12
-
-
0025910287
-
The bmi-1 and mel-18 gene products define a new family of DNA-binding proteins involved in cell proliferation and tumorigenesis
-
Goebl MG. The bmi-1 and mel-18 gene products define a new family of DNA-binding proteins involved in cell proliferation and tumorigenesis. Cell. 66:1992;623.
-
(1992)
Cell
, vol.66
, pp. 623
-
-
Goebl, M.G.1
-
13
-
-
0028840713
-
Mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity
-
Kanno M, Hasegawa M, Ishida A, Isono K, Taniguchi M. mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. EMBO J. 14:1995;5672-5678.
-
(1995)
EMBO J
, vol.14
, pp. 5672-5678
-
-
Kanno, M.1
Hasegawa, M.2
Ishida, A.3
Isono, K.4
Taniguchi, M.5
-
14
-
-
0031050261
-
Identification of Bmi-interacting proteins as constituents of a multimeric mammalian Polycomb complex
-
of special interest. M33, Bmi1, and Mph1 proteins show an overlapping speckled distribution in the interphase nuclei of the U2-OS cell line and coimmunoprecipitation experiments indicate that these three proteins are constituents of a multiprotein complex. Protein truncation experiments show that the Mph1 carboxyl terminus, including the conserved SEP domain, is required for homodimerisation and interaction with a central domain of Bmi1. Together, these data provide evidence for the existence of a multimeric mammalian PcG complex, similar to that in Drosophila.
-
Alkema MJ, Bronk M, Verhoeven E, Otte A, van 't Veer LJ, Berns A, van Lohuizen M. Identification of Bmi-interacting proteins as constituents of a multimeric mammalian Polycomb complex. of special interest Genes Dev. 11:1997;226-240 M33, Bmi1, and Mph1 proteins show an overlapping speckled distribution in the interphase nuclei of the U2-OS cell line and coimmunoprecipitation experiments indicate that these three proteins are constituents of a multiprotein complex. Protein truncation experiments show that the Mph1 carboxyl terminus, including the conserved SEP domain, is required for homodimerisation and interaction with a central domain of Bmi1. Together, these data provide evidence for the existence of a multimeric mammalian PcG complex, similar to that in Drosophila.
-
(1997)
Genes Dev
, vol.11
, pp. 226-240
-
-
Alkema, M.J.1
Bronk, M.2
Verhoeven, E.3
Otte, A.4
Van 't Veer, L.J.5
Berns, A.6
Van Lohuizen, M.7
-
15
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
-
Van der Lugt NMT, Domen J, Linders K, van Room M, Robanus-Maandag E, te Riele H, van der Valk M, Deschamps J, Sofroniew M, van Lohuizen M, Berns A. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes Dev. 8:1994;757-769.
-
(1994)
Genes Dev
, vol.8
, pp. 757-769
-
-
Van Der Lugt, N.M.T.1
Domen, J.2
Linders, K.3
Van Room, M.4
Robanus-Maandag, E.5
Te Riele, H.6
Van Der Valk, M.7
Deschamps, J.8
Sofroniew, M.9
Van Lohuizen, M.10
Berns, A.11
-
16
-
-
0029891279
-
A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton
-
of special interest. Disruption of the Posterior sex combs homologue mel18 is described. In addition to postnatal effects on cell growth, mice lacking mel18 display posterior transformations of the axial skeleton and corresponding anterior shifts in expression of a number of Hox genes. The subset of Hox genes affected is only partially overlapping with those misregulated in Bmi1 mutants and some Hox genes are not affected in either mel18 or Bmi1 knockouts, suggesting that individual PcG genes may have varying affinities or specificities for different subsets of Hox genes (for comparison, see [17]).
-
Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, Koseki H. A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. of special interest Development. 122:1996;1513-1522 Disruption of the Posterior sex combs homologue mel18 is described. In addition to postnatal effects on cell growth, mice lacking mel18 display posterior transformations of the axial skeleton and corresponding anterior shifts in expression of a number of Hox genes. The subset of Hox genes affected is only partially overlapping with those misregulated in Bmi1 mutants and some Hox genes are not affected in either mel18 or Bmi1 knockouts, suggesting that individual PcG genes may have varying affinities or specificities for different subsets of Hox genes (for comparison, see [17]).
-
(1996)
Development
, vol.122
, pp. 1513-1522
-
-
Akasaka, T.1
Kanno, M.2
Balling, R.3
Mieza, M.A.4
Taniguchi, M.5
Koseki, H.6
-
17
-
-
0030218039
-
The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression
-
Van der Lugt N, Alkema M, Berns A, Deschamps J. The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression. Mech Dev. 58:1996;153-164.
-
(1996)
Mech Dev
, vol.58
, pp. 153-164
-
-
Van Der Lugt, N.1
Alkema, M.2
Berns, A.3
Deschamps, J.4
-
18
-
-
0029143166
-
Compound mutants for the paralogous Hoxa-4, Hoxb-4 and Hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrate transformed
-
Horan G, Ramirez-Solis R, Featherstone M, Wolgemuth D, Bradley A, Behringer R. Compound mutants for the paralogous Hoxa-4, Hoxb-4 and Hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrate transformed. Genes Dev. 9:1995;1667-1677.
-
(1995)
Genes Dev
, vol.9
, pp. 1667-1677
-
-
Horan, G.1
Ramirez-Solis, R.2
Featherstone, M.3
Wolgemuth, D.4
Bradley, A.5
Behringer, R.6
-
19
-
-
0028923508
-
Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice
-
Alkema MJ, van der Lugt NMT, Bobeldijk RC, Berns A, van Lohuizen M. Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice. Nature. 374:1995;724-727.
-
(1995)
Nature
, vol.374
, pp. 724-727
-
-
Alkema, M.J.1
Van Der Lugt, N.M.T.2
Bobeldijk, R.C.3
Berns, A.4
Van Lohuizen, M.5
-
20
-
-
0026594541
-
The mouse has a Polycomb-like chromobox gene
-
Pearce J, Singh P, Gaunt S. The mouse has a Polycomb-like chromobox gene. Development. 114:1992;921-929.
-
(1992)
Development
, vol.114
, pp. 921-929
-
-
Pearce, J.1
Singh, P.2
Gaunt, S.3
-
21
-
-
0029145512
-
Function of the Polycomb protein is conserved in mice and files
-
Müller J, Gaunt S, Lawrence P. Function of the Polycomb protein is conserved in mice and files. Development. 121:1995;2847-2852.
-
(1995)
Development
, vol.121
, pp. 2847-2852
-
-
Müller, J.1
Gaunt, S.2
Lawrence, P.3
-
22
-
-
0031049215
-
Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice
-
Coré N, Bel S, Gaunt SJ, Aurrens-Lions M, Pearce J, Fisher A, Djabali M. Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. Development. 124:1997;721-729.
-
(1997)
Development
, vol.124
, pp. 721-729
-
-
Coré, N.1
Bel, S.2
Gaunt, S.J.3
Aurrens-Lions, M.4
Pearce, J.5
Fisher, A.6
Djabali, M.7
-
23
-
-
0029841672
-
Positional cloning of a global regulator of anterior-posterior patterning in mice
-
of outstanding interest. Partial loss of eed function causes posterior transformations of the axial skeleton and the positional cloning of the eed locus reported here reveals it to be homologous to the Drosophila PcG gene extra sex combs. Surprisingly for a PcG member, complete lack of eed function disrupts A - P patterning at very early stages, suggesting that this gene might have an input into the establishment of Hox gene expression.
-
Schumacher A, Faust C, Magnuson T. Positional cloning of a global regulator of anterior-posterior patterning in mice. of outstanding interest Nature. 383:1996;250-253 Partial loss of eed function causes posterior transformations of the axial skeleton and the positional cloning of the eed locus reported here reveals it to be homologous to the Drosophila PcG gene extra sex combs. Surprisingly for a PcG member, complete lack of eed function disrupts A - P patterning at very early stages, suggesting that this gene might have an input into the establishment of Hox gene expression.
-
(1996)
Nature
, vol.383
, pp. 250-253
-
-
Schumacher, A.1
Faust, C.2
Magnuson, T.3
-
24
-
-
0028910338
-
The eed mutation disrupts anterior mesoderm production in mice
-
Faust C, Schumacher A, Holdener B, Magnuson T. The eed mutation disrupts anterior mesoderm production in mice. Development. 121:1995;273-285.
-
(1995)
Development
, vol.121
, pp. 273-285
-
-
Faust, C.1
Schumacher, A.2
Holdener, B.3
Magnuson, T.4
-
25
-
-
0027953771
-
Hox genes in vertebrate development
-
Krumlauf R. Hox genes in vertebrate development. Cell. 78:1994;191-201.
-
(1994)
Cell
, vol.78
, pp. 191-201
-
-
Krumlauf, R.1
-
26
-
-
0028100291
-
Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes
-
McKeon J, Slade E, Sinclair DA, Cheng N, Couling M, Brock HW. Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes. Mol Gen Genet. 244:1994;474-483.
-
(1994)
Mol Gen Genet
, vol.244
, pp. 474-483
-
-
McKeon, J.1
Slade, E.2
Sinclair, D.A.3
Cheng, N.4
Couling, M.5
Brock, H.W.6
-
28
-
-
0028869112
-
Altered Hox expression and segmental identity in MII mutant mice
-
Yu B, Hess J, Horning S, Brown G, Korsmeyer S. Altered Hox expression and segmental identity in MII mutant mice. Nature. 378:1995;505-508.
-
(1995)
Nature
, vol.378
, pp. 505-508
-
-
Yu, B.1
Hess, J.2
Horning, S.3
Brown, G.4
Korsmeyer, S.5
-
29
-
-
0028224671
-
Isolation and characterisation of retinoic acid-inducible cDNA clones in F9 cells: One of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila Polyhomeotic protein
-
Nomura M, Takihara Y, Shimada K. Isolation and characterisation of retinoic acid-inducible cDNA clones in F9 cells: one of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila Polyhomeotic protein. Differentiation. 57:1994;39-50.
-
(1994)
Differentiation
, vol.57
, pp. 39-50
-
-
Nomura, M.1
Takihara, Y.2
Shimada, K.3
-
30
-
-
0030999876
-
Identification and characterisation of interactions between the vertebrate Polycomb-group protein BMI1 and human homologs of Polyhomeotic
-
Gunster MJ, Satijn DPE, Hamer KM, den Blaauwen JL, de Bruijn D, Alkema MJ, van Lohuizen M, van Driel R, Otte AP. Identification and characterisation of interactions between the vertebrate Polycomb-group protein BMI1 and human homologs of Polyhomeotic. Mol Cell Biol. 17:1997;2326-2335.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2326-2335
-
-
Gunster, M.J.1
Satijn, D.P.E.2
Hamer, K.M.3
Den Blaauwen, J.L.4
De Bruijn, D.5
Alkema, M.J.6
Van Lohuizen, M.7
Van Driel, R.8
Otte, A.P.9
-
31
-
-
0029922115
-
Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene
-
Hobert O, Sures I, Ciossek T, Fuchs M, Ullrich A. Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene. Mech Dev. 55:1996;171-184.
-
(1996)
Mech Dev
, vol.55
, pp. 171-184
-
-
Hobert, O.1
Sures, I.2
Ciossek, T.3
Fuchs, M.4
Ullrich, A.5
-
32
-
-
0030038664
-
E(z): A Polycomb group gene or a trithorax group gene?
-
Lajeunesse D, Shearn A. E(z): a Polycomb group gene or a trithorax group gene? Development. 122:1996;2189-2197.
-
(1996)
Development
, vol.122
, pp. 2189-2197
-
-
Lajeunesse, D.1
Shearn, A.2
-
33
-
-
0028088336
-
Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: The one hybrid system
-
Inouye C, Remondelli P, Karin M, Elledge S. Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: the one hybrid system. DNA Cell Biol. 13:1994;731-742.
-
(1994)
DNA Cell Biol
, vol.13
, pp. 731-742
-
-
Inouye, C.1
Remondelli, P.2
Karin, M.3
Elledge, S.4
-
34
-
-
0027493251
-
BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription
-
Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature. 366:1993;170-174.
-
(1993)
Nature
, vol.366
, pp. 170-174
-
-
Khavari, P.A.1
Peterson, C.L.2
Tamkun, J.W.3
Mendel, D.B.4
Crabtree, G.R.5
-
35
-
-
0027434083
-
A human homologue of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma genes potentiates transcriptional activation by the glucocorticoid receptor
-
Muchardt C, Yaniv M. A human homologue of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12:1993;4279-4290.
-
(1993)
EMBO J
, vol.12
, pp. 4279-4290
-
-
Muchardt, C.1
Yaniv, M.2
-
36
-
-
0028157043
-
Brg1: A putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator
-
Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J. brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Dev Biol. 161:1993;229-242.
-
(1993)
Dev Biol
, vol.161
, pp. 229-242
-
-
Randazzo, F.M.1
Khavari, P.2
Crabtree, G.3
Tamkun, J.4
Rossant, J.5
-
37
-
-
0028987268
-
The SWI-SNF complex: A chromatin remodelling machine
-
Peterson CL, Tamkun JW. The SWI-SNF complex: a chromatin remodelling machine. Trends Biochem Sci. 20:1995;143-146.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 143-146
-
-
Peterson, C.L.1
Tamkun, J.W.2
-
38
-
-
0028566214
-
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5
-
Kalpana GV, Marmon S, Wang W, Crabtree GR. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science. 266:1994;2002-2006.
-
(1994)
Science
, vol.266
, pp. 2002-2006
-
-
Kalpana, G.V.1
Marmon, S.2
Wang, W.3
Crabtree, G.R.4
-
39
-
-
0028947217
-
A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm
-
Muchardt C, Sardet C, Bourachot B, Onufryk C, Yaniv M. A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm. Nucleic Acids Res. 23:1995;1127-1132.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1127-1132
-
-
Muchardt, C.1
Sardet, C.2
Bourachot, B.3
Onufryk, C.4
Yaniv, M.5
-
40
-
-
0029008811
-
The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex
-
Dingwall AK, Beek SJ, McCallum CM, Tamkun JW, Kalpana GV, Goff SP, Scott MP. The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex. Mol Biol Cell. 6:1995;777-791.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 777-791
-
-
Dingwall, A.K.1
Beek, S.J.2
McCallum, C.M.3
Tamkun, J.W.4
Kalpana, G.V.5
Goff, S.P.6
Scott, M.P.7
-
41
-
-
0030033699
-
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling
-
Wilson CJ, Chao DM, Imbalzano AN, Schnitzler GR, Kingston RE, Young RA. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell. 84:1996;235-244.
-
(1996)
Cell
, vol.84
, pp. 235-244
-
-
Wilson, C.J.1
Chao, D.M.2
Imbalzano, A.N.3
Schnitzler, G.R.4
Kingston, R.E.5
Young, R.A.6
-
42
-
-
0029787059
-
Diversity and specialisation of mammalian SWI/SNF complexes
-
Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR. Diversity and specialisation of mammalian SWI/SNF complexes. Genes Dev. 10:1996;2117-2130.
-
(1996)
Genes Dev
, vol.10
, pp. 2117-2130
-
-
Wang, W.1
Xue, Y.2
Zhou, S.3
Kuo, A.4
Cairns, B.R.5
Crabtree, G.R.6
-
43
-
-
0028800024
-
Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes
-
Subramanian V, Meyer BI, Gruss P. Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell. 83:1995;641-653.
-
(1995)
Cell
, vol.83
, pp. 641-653
-
-
Subramanian, V.1
Meyer, B.I.2
Gruss, P.3
-
44
-
-
0030937750
-
Homeosis and intestinal tumours in Cdx2 mutant mice
-
of special interest. Loss of murine Cdx2 function results in peri-implantation embryonic lethality as a result of extra-embryonic deficits. Cdx2 heterozygous mutants, however, display anterior homeotic shifts of the axial skeleton and later in adult life they frequently develop intestinal polyps, occasionally containing areas of true metaplasia. These homeotic and proliferative phenotypes are similar to those expected for a mammalian trxG gene.
-
Chawengsaksophak K, James R, Hammond VE, Kontgen F, Beck F. Homeosis and intestinal tumours in Cdx2 mutant mice. of special interest Nature. 386:1997;84-87 Loss of murine Cdx2 function results in peri-implantation embryonic lethality as a result of extra-embryonic deficits. Cdx2 heterozygous mutants, however, display anterior homeotic shifts of the axial skeleton and later in adult life they frequently develop intestinal polyps, occasionally containing areas of true metaplasia. These homeotic and proliferative phenotypes are similar to those expected for a mammalian trxG gene.
-
(1997)
Nature
, vol.386
, pp. 84-87
-
-
Chawengsaksophak, K.1
James, R.2
Hammond, V.E.3
Kontgen, F.4
Beck, F.5
-
45
-
-
15844394270
-
An MII-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
-
Corral J, Lavenir I, Impey H, Warren AJ, Forster A, Larson TA, Bell S, McKenzie ANJ, King G, Rabbits TH. An MII-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell. 85:1996;853-861.
-
(1996)
Cell
, vol.85
, pp. 853-861
-
-
Corral, J.1
Lavenir, I.2
Impey, H.3
Warren, A.J.4
Forster, A.5
Larson, T.A.6
Bell, S.7
McKenzie, A.N.J.8
King, G.9
Rabbits, T.H.10
-
46
-
-
0025863346
-
Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging
-
Van Lohuizen M, Verbeek S, Scheijen B, Wientjens E, van der Gulden H, Berns A. Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging. Cell. 65:1991;737-752.
-
(1991)
Cell
, vol.65
, pp. 737-752
-
-
Van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
Van Der Gulden, H.5
Berns, A.6
-
47
-
-
0025727771
-
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice
-
Haupt Y, Alexander WS, Barri G, Klinken SP, Adams JM. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice. Cell. 65:1991;753-763.
-
(1991)
Cell
, vol.65
, pp. 753-763
-
-
Haupt, Y.1
Alexander, W.S.2
Barri, G.3
Klinken, S.P.4
Adams, J.M.5
-
48
-
-
0029899685
-
Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression
-
Hobert O, Jallal B, Ullrich A. Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression. Mol Cell Biol. 16:1996;3066-3073.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3066-3073
-
-
Hobert, O.1
Jallal, B.2
Ullrich, A.3
-
49
-
-
0026485281
-
Homeobox genes in normal hematopoiesis and leukemia
-
Lawrence HJ, Largman C. Homeobox genes in normal hematopoiesis and leukemia. Blood. 80:1992;2445-2453.
-
(1992)
Blood
, vol.80
, pp. 2445-2453
-
-
Lawrence, H.J.1
Largman, C.2
-
50
-
-
0028124772
-
Mice with targeted disruptions in the paralogous genes Hoxa-3 and Hoxd-3 reveal synergistic interactions
-
Condie BG, Capecchi MR. Mice with targeted disruptions in the paralogous genes Hoxa-3 and Hoxd-3 reveal synergistic interactions. Nature. 370:1994;304-307.
-
(1994)
Nature
, vol.370
, pp. 304-307
-
-
Condie, B.G.1
Capecchi, M.R.2
-
51
-
-
0029148913
-
Vertebrate Hox genes and proliferation: An alternative pathway to homeosis?
-
Duboule D. Vertebrate Hox genes and proliferation: an alternative pathway to homeosis? Curr Opin Genet Dev. 5:1995;525-528.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 525-528
-
-
Duboule, D.1
-
52
-
-
0031031397
-
2/M cell-cycle checkpoint
-
2 arrest probably via an interaction with protein phosphatase1 and protein serine/threonine phosphatase 2A, raising the interesting possibility that other homeobox genes such as the Hox network might influence the cell cycle by direct interaction with protein phosphatases.
-
2 arrest probably via an interaction with protein phosphatase1 and protein serine/threonine phosphatase 2A, raising the interesting possibility that other homeobox genes such as the Hox network might influence the cell cycle by direct interaction with protein phosphatases.
-
(1997)
Nature
, vol.385
, pp. 454-458
-
-
Kawabe, T.1
Muslin, A.J.2
Korsmeyer, S.J.3
-
53
-
-
0026503711
-
Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products
-
Simon J, Chiang A, Bender W. Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development. 114:1992;493-505.
-
(1992)
Development
, vol.114
, pp. 493-505
-
-
Simon, J.1
Chiang, A.2
Bender, W.3
-
54
-
-
0000396280
-
The bithorax complex: Control of segmental identity
-
Peifer M, Karch F, Bender W. The bithorax complex: control of segmental identity. Genes Dev. 1:1987;891-898.
-
(1987)
Genes Dev
, vol.1
, pp. 891-898
-
-
Peifer, M.1
Karch, F.2
Bender, W.3
-
55
-
-
0025202707
-
Imprinting a determined state into the chromatin of Drosophila
-
Paro R. Imprinting a determined state into the chromatin of Drosophila. Trends Genet. 6:1990;416-421.
-
(1990)
Trends Genet
, vol.6
, pp. 416-421
-
-
Paro, R.1
-
56
-
-
0029797949
-
Retinoids and Hox genes
-
Marshall H, Morrison A, Studer M, Pöpperl H, Krumlauf R. Retinoids and Hox genes. FASEB J. 10:1996;969-978.
-
(1996)
FASEB J
, vol.10
, pp. 969-978
-
-
Marshall, H.1
Morrison, A.2
Studer, M.3
Pöpperl, H.4
Krumlauf, R.5
-
57
-
-
0028239595
-
Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic cid receptor
-
Chiba H, Muramatsu M, Nomoto A, Kato H. Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic cid receptor. Nucleic Acids Res. 22:1994;1815-1820.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1815-1820
-
-
Chiba, H.1
Muramatsu, M.2
Nomoto, A.3
Kato, H.4
-
58
-
-
0028213501
-
A role of Polycomb group genes in the regulation of gap gene expression in Drosophila
-
Pelegri F, Lehmann R. A role of Polycomb group genes in the regulation of gap gene expression in Drosophila. Genetics. 136:1994;1341-1353.
-
(1994)
Genetics
, vol.136
, pp. 1341-1353
-
-
Pelegri, F.1
Lehmann, R.2
-
59
-
-
0031003129
-
Positive cross-regulation and enhancer sharing: Two mechanisms for specificying overlapping Hox expression patterns
-
Gould A, Morrison A, Sproat G, White R, Krumlauf R. Positive cross-regulation and enhancer sharing: two mechanisms for specificying overlapping Hox expression patterns. Genes Dev. 11:1997;900-913.
-
(1997)
Genes Dev
, vol.11
, pp. 900-913
-
-
Gould, A.1
Morrison, A.2
Sproat, G.3
White, R.4
Krumlauf, R.5
-
60
-
-
0031000434
-
PcG complexes and chromatin silencing
-
Pirrotta V. PcG complexes and chromatin silencing. Curr Opin Genet Dev. 7:1997;249-258.
-
(1997)
Curr Opin Genet Dev
, vol.7
, pp. 249-258
-
-
Pirrotta, V.1
-
61
-
-
0030945893
-
Murine Polycomb- And Trithorax-group genes regulate homeotic pathways and beyond
-
Schumacher A, Magnuson T. Murine Polycomb- and Trithorax-group genes regulate homeotic pathways and beyond. Trends Genet. 13:1997;167-170.
-
(1997)
Trends Genet
, vol.13
, pp. 167-170
-
-
Schumacher, A.1
Magnuson, T.2
|