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Volumn 89, Issue 2, 2003, Pages 871-883

Binding sites, singly bound states, and conformation coupling shape GABA-evoked currents

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR;

EID: 0037319323     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00951.2002     Document Type: Article
Times cited : (78)

References (42)
  • 1
    • 0030657416 scopus 로고    scopus 로고
    • Immunoglobulins from motoneurone disease patients enhance glutamate release from rat hippocampal neurones in culture
    • Andjus PR, Stevic-Marinkovic Z, and Cherubini E. Immunoglobulins from motoneurone disease patients enhance glutamate release from rat hippocampal neurones in culture. J Physiol 504: 103-112, 1997.
    • (1997) J Physiol , vol.504 , pp. 103-112
    • Andjus, P.R.1    Stevic-Marinkovic, Z.2    Cherubini, E.3
  • 3
    • 0034143418 scopus 로고    scopus 로고
    • A receptors in CA1 pyramidal cells
    • A receptors in CA1 pyramidal cells. J Neurosci 20: 937-948, 2000.
    • (2000) J Neurosci , vol.20 , pp. 937-948
    • Banks, M.I.1    Pearce, R.A.2
  • 5
    • 0032054456 scopus 로고    scopus 로고
    • ++ via changes of their desensitization kinetics: An in situ patch-clamp and single-cell PCR study
    • ++ via changes of their desensitization kinetics: an in situ patch-clamp and single-cell PCR study. J Neurosci 18: 2437-2448, 1998.
    • (1998) J Neurosci , vol.18 , pp. 2437-2448
    • Berger, T.1    Schwarz, C.2    Kraushaar, U.3    Monyer, H.4
  • 7
    • 0024312649 scopus 로고
    • Desensitization of the acetylcholine receptor of frog end-plates measured in a vaseline-gap voltage clamp
    • Cachelin AB and Colquhoun D. Desensitization of the acetylcholine receptor of frog end-plates measured in a vaseline-gap voltage clamp. J Physiol 415: 159-188, 1989.
    • (1989) J Physiol , vol.415 , pp. 159-188
    • Cachelin, A.B.1    Colquhoun, D.2
  • 8
    • 0028178459 scopus 로고
    • Multiphasic desensitization of the GABAA receptor in outside-out patches
    • Celentano JJ and Wong RK. Multiphasic desensitization of the GABAA receptor in outside-out patches. Biophys J 66: 1039-1050, 1994.
    • (1994) Biophys J , vol.66 , pp. 1039-1050
    • Celentano, J.J.1    Wong, R.K.2
  • 9
    • 0035282615 scopus 로고    scopus 로고
    • Generating diversity at GABAergic synapses
    • Cherubini E and Conti F. Generating diversity at GABAergic synapses. Trends Neurosci. 24: 155-162, 2001.
    • (2001) Trends Neurosci. , vol.24 , pp. 155-162
    • Cherubini, E.1    Conti, F.2
  • 10
    • 0029876527 scopus 로고    scopus 로고
    • Transmitter time course in the synaptic cleft: Its role in central synaptic function
    • Clements JD. Transmitter time course in the synaptic cleft: its role in central synaptic function. Trends Neurosci 19: 163-170, 1996.
    • (1996) Trends Neurosci , vol.19 , pp. 163-170
    • Clements, J.D.1
  • 11
    • 0031973872 scopus 로고    scopus 로고
    • Activation kinetics of AMPA receptor channels reveal the number of functional agonist binding sites
    • Clements JD, Feltz A, Sahara Y, and Westbrook GL. Activation kinetics of AMPA receptor channels reveal the number of functional agonist binding sites. J Neurosci 18: 119-127, 1998.
    • (1998) J Neurosci , vol.18 , pp. 119-127
    • Clements, J.D.1    Feltz, A.2    Sahara, Y.3    Westbrook, G.L.4
  • 12
    • 0032199006 scopus 로고    scopus 로고
    • Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
    • Colquhoun D. Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125: 924-947, 1998.
    • (1998) Br J Pharmacol , vol.125 , pp. 924-947
    • Colquhoun, D.1
  • 13
    • 0027749606 scopus 로고
    • Molecular pharmacology. The binding issue
    • Colquhoun D and Farrant M. Molecular pharmacology. The binding issue. Nature 366: 510-511, 1993.
    • (1993) Nature , vol.366 , pp. 510-511
    • Colquhoun, D.1    Farrant, M.2
  • 14
    • 0023655008 scopus 로고
    • Liquid filament switch for ultra-fast exchanges of solutions at excised patches at synaptic membranes of crayfish muscle
    • Franke CH and Dudel J. Liquid filament switch for ultra-fast exchanges of solutions at excised patches at synaptic membranes of crayfish muscle. Neurosci Lett 77: 199-204, 1987.
    • (1987) Neurosci Lett , vol.77 , pp. 199-204
    • Franke, C.H.1    Dudel, J.2
  • 15
    • 0028825692 scopus 로고
    • Variation in GABA mini amplitude is the consequence of variation in transmitter concentration
    • Frerking M, Borges S, and Wilson M. Variation in GABA mini amplitude is the consequence of variation in transmitter concentration. Neuron 15: 885-895, 1995.
    • (1995) Neuron , vol.15 , pp. 885-895
    • Frerking, M.1    Borges, S.2    Wilson, M.3
  • 16
    • 0030176349 scopus 로고    scopus 로고
    • Saturation of postsynaptic receptors at central synapses?
    • Frerking M and Wilson M. Saturation of postsynaptic receptors at central synapses? Curr Opin Neurobiol 6: 395-403, 1996.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 395-403
    • Frerking, M.1    Wilson, M.2
  • 17
    • 0029416984 scopus 로고
    • A receptor gating kinetics on the α-subunit isoform: Implications for structure-function relations and synaptic transmission
    • A receptor gating kinetics on the α-subunit isoform: implications for structure-function relations and synaptic transmission. J Physiol 489: 529-543, 1995.
    • (1995) J Physiol , vol.489 , pp. 529-543
    • Gingrich, K.J.1    Roberts, W.A.2    Kass, R.S.3
  • 18
    • 0032945358 scopus 로고    scopus 로고
    • A receptor currents in mouse fibroblasts
    • A receptor currents in mouse fibroblasts. J Physiol 514: 27-45, 1999.
    • (1999) J Physiol , vol.514 , pp. 27-45
    • Haas, K.F.1    Macdonald, R.L.2
  • 19
    • 0242478977 scopus 로고    scopus 로고
    • Cell type- and synapse-specific variability in synaptic GABAA receptor occupancy
    • Hajos N, Nusser Z, Rancz EA, Freund TF, and Mody I. Cell type- and synapse-specific variability in synaptic GABAA receptor occupancy. Eur J Neurosci 12: 810-818, 2000.
    • (2000) Eur J Neurosci , vol.12 , pp. 810-818
    • Hajos, N.1    Nusser, Z.2    Rancz, E.A.3    Freund, T.F.4    Mody, I.5
  • 20
    • 0001736094 scopus 로고
    • Perfection of a synaptic receptor: Kinetics and energetics of the acetylcholine receptor
    • Jackson MB. Perfection of a synaptic receptor: kinetics and energetics of the acetylcholine receptor. Proc Natl Acad Sci USA 86: 2199-2203, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2199-2203
    • Jackson, M.B.1
  • 21
    • 0001941068 scopus 로고
    • Fast application of agonists to isolated membrane patches
    • edited by Sakmann B and Neher E. New York: Plenum Press
    • Jonas P. Fast application of agonists to isolated membrane patches. In: Single-Channel Recording, edited by Sakmann B and Neher E. New York: Plenum Press, 1995, p. 231-243.
    • (1995) Single-Channel Recording , pp. 231-243
    • Jonas, P.1
  • 23
    • 0029112106 scopus 로고
    • A channel responses to brief agonist pulses
    • A channel responses to brief agonist pulses. Neuron 15: 181-191, 1995.
    • (1995) Neuron , vol.15 , pp. 181-191
    • Jones, M.V.1    Westbrook, G.L.2
  • 24
    • 0030867840 scopus 로고    scopus 로고
    • Shaping of IPSCs by endogenous calcineurin activity
    • Jones MV and Westbrook GL. Shaping of IPSCs by endogenous calcineurin activity. J Neurosci 17: 7626-7633, 1997.
    • (1997) J Neurosci , vol.17 , pp. 7626-7633
    • Jones, M.V.1    Westbrook, G.L.2
  • 25
    • 84965075853 scopus 로고
    • A study of the 'desensitization' produced by acetylcholine at the motor end-plate
    • Katz B and Thesleff S. A study of the 'desensitization' produced by acetylcholine at the motor end-plate. J Physiol 138: 63-80, 1957.
    • (1957) J Physiol , vol.138 , pp. 63-80
    • Katz, B.1    Thesleff, S.2
  • 26
    • 0030734159 scopus 로고    scopus 로고
    • Activation and deactivation rates of recombinant GABAA receptor channels are dependent on α-subunit isoform
    • Lavoie AM, Tingey JJ, Harrison NL, Pritchett DB, and Twyman RE. Activation and deactivation rates of recombinant GABAA receptor channels are dependent on α-subunit isoform. Biophys J 73: 2518-2526, 1999.
    • (1999) Biophys J , vol.73 , pp. 2518-2526
    • Lavoie, A.M.1    Tingey, J.J.2    Harrison, N.L.3    Pritchett, D.B.4    Twyman, R.E.5
  • 27
    • 0034143449 scopus 로고    scopus 로고
    • A receptor kinetics: Evidence for slowed agonist unbinding
    • A receptor kinetics: evidence for slowed agonist unbinding. J Neurosci 20: 899-907, 2000.
    • (2000) J Neurosci , vol.20 , pp. 899-907
    • Li, X.1    Pearce, R.A.2
  • 28
    • 0024474066 scopus 로고
    • A receptor of main conductance state of mouse spinal cord neurones in culture
    • A receptor of main conductance state of mouse spinal cord neurones in culture. J Physiol 410: 479-499, 1989.
    • (1989) J Physiol , vol.410 , pp. 479-499
    • Macdonald, R.L.1    Rogers, C.J.2    Twyman, R.E.3
  • 30
    • 0015340428 scopus 로고
    • A quantitative description of end-plate currents
    • Magleby KL and Stevens CF. A quantitative description of end-plate currents. J Physiol 223: 173-197, 1972.
    • (1972) J Physiol , vol.223 , pp. 173-197
    • Magleby, K.L.1    Stevens, C.F.2
  • 31
    • 0033563320 scopus 로고    scopus 로고
    • A receptor subunit composition and functional properties of Cl-channels with differential sensitivity to zolpidem in embryonic rat hippocampal cells
    • A receptor subunit composition and functional properties of Cl-channels with differential sensitivity to zolpidem in embryonic rat hippocampal cells. J Neurosci 19: 4921-4937, 1999.
    • (1999) J Neurosci , vol.19 , pp. 4921-4937
    • Maric, D.1    Maric, I.2    Wen, X.3    Fritschy, J.M.4    Sieghart, W.5    Barker, J.L.6    Serafini, R.7
  • 35
    • 0035116149 scopus 로고    scopus 로고
    • Synapse-specific contribution of the variation of transmitter concentration to the decay of inhibitory postsynaptic currents
    • Nusser Z, Naylor D, and Mody I. Synapse-specific contribution of the variation of transmitter concentration to the decay of inhibitory postsynaptic currents. Biophys J 80: 1251-1261, 2001.
    • (2001) Biophys J , vol.80 , pp. 1251-1261
    • Nusser, Z.1    Naylor, D.2    Mody, I.3
  • 37
    • 0033556355 scopus 로고    scopus 로고
    • Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses
    • Perrais D and Ropert N. Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses. J Neurosci 19: 578-588, 1999.
    • (1999) J Neurosci , vol.19 , pp. 578-588
    • Perrais, D.1    Ropert, N.2
  • 38
    • 0028031943 scopus 로고
    • Functional diversity of GABA-activated Cl-currents in Purkinje versus granule neurons in rat cerebellar slices
    • Puia G, Costa E, and Vicini S. Functional diversity of GABA-activated Cl-currents in Purkinje versus granule neurons in rat cerebellar slices. Neuron 12: 117-126, 1994.
    • (1994) Neuron , vol.12 , pp. 117-126
    • Puia, G.1    Costa, E.2    Vicini, S.3
  • 41
    • 0025257507 scopus 로고
    • A receptor main conductance state of mouse spinal cord neurones in culture
    • A receptor main conductance state of mouse spinal cord neurones in culture. J Physiol 423: 193-220, 1990.
    • (1990) J Physiol , vol.423 , pp. 193-220
    • Twyman, R.E.1    Rogers, C.J.2    Macdonald, R.L.3
  • 42
    • 0035141668 scopus 로고    scopus 로고
    • Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation
    • Wagner DA and Czajkowski C. Structure and dynamics of the GABA binding pocket: a narrowing cleft that constricts during activation. J Neurosci 21: 67-74, 2001.
    • (2001) J Neurosci , vol.21 , pp. 67-74
    • Wagner, D.A.1    Czajkowski, C.2


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