Chlorpromazine inhibits miniature GABAergic currents by reducing the binding and by increasing the unbinding rate of GABA(A) receptors

Journal of Neuroscience

Volumn 19, Issue 7, 1999, Pages 2474-2488

  Mozrzymas, Jerzy W ^a,b   Barberis, Andrea ^a   Michalak, Krystyna ^b   Cherubini, Enrico ^a  

^a SISSA   (Italy)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Binding and unbinding rate constants; Chlorpromazine; GABA(A) receptors; Hippocampus; Miniature IPSCs; Patch clamp

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CHLORPROMAZINE;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ANIMAL CELL; ARTICLE; DRUG EFFECT; DRUG RECEPTOR BINDING; MENTAL DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SYNAPTIC TRANSMISSION;

EID: 0033118570     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-07-02474.1999     Document Type: Article

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