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Volumn 23, Issue 3, 2003, Pages 842-851

Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN ADE2; PROTEIN NMD; PROTEIN NMD2; PROTEIN PGK1; PROTEIN UPF; PROTEIN UPF1; PROTEIN UPF3; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 0037304372     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.3.842-851.2003     Document Type: Article
Times cited : (67)

References (91)
  • 1
    • 0030826508 scopus 로고    scopus 로고
    • Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay
    • Atkin, A., L. Schenkman, M. Eastham, J. Dahlseid, M. Lelivelt, and M. Culbertson. 1997. Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay. J. Biol. Chem. 272:22163-22172.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22163-22172
    • Atkin, A.1    Schenkman, L.2    Eastham, M.3    Dahlseid, J.4    Lelivelt, M.5    Culbertson, M.6
  • 2
    • 0029006870 scopus 로고
    • The majority of yeast UPF1 colocalizes with polyribosomes in the cytoplasm
    • Atkin, A., N. Altamura, P. Leeds, and M. Culbertson. 1995. The majority of yeast UPF1 colocalizes with polyribosomes in the cytoplasm. Mol. Cell. Biol. 6:611-625.
    • (1995) Mol. Cell. Biol. , vol.6 , pp. 611-625
    • Atkin, A.1    Altamura, N.2    Leeds, P.3    Culbertson, M.4
  • 3
    • 0029758321 scopus 로고    scopus 로고
    • An essential component of the decapping enzyme required for normal rates of mRNA turnover
    • Beelman, C., A. Stevens, G. Caponigro, T. LaGrandeur, L. Hatfield, and R. Parker. 1996. An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature 382:642-646.
    • (1996) Nature , vol.382 , pp. 642-646
    • Beelman, C.1    Stevens, A.2    Caponigro, G.3    LaGrandeur, T.4    Hatfield, L.5    Parker, R.6
  • 4
    • 0032819710 scopus 로고    scopus 로고
    • Overexpression of truncated Nmd3p inhibits protein synthesis in yeast
    • Belk, J., F. He, and A. Jacobson. 1999. Overexpression of truncated Nmd3p inhibits protein synthesis in yeast. RNA 5:1055-1070.
    • (1999) RNA , vol.5 , pp. 1055-1070
    • Belk, J.1    He, F.2    Jacobson, A.3
  • 5
    • 0031897326 scopus 로고    scopus 로고
    • Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis
    • Benard, L., K. Carroll, R. Valle, and R. Wickner. 1998. Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol. Cell. Biol. 18:2688-2696.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2688-2696
    • Benard, L.1    Carroll, K.2    Valle, R.3    Wickner, R.4
  • 6
    • 0029153552 scopus 로고
    • The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae
    • Bonetti, B., L. Fu, J. Moon, and D. M. Bedwell. 1995. The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae. J. Mol. Biol. 251:334-345.
    • (1995) J. Mol. Biol. , vol.251 , pp. 334-345
    • Bonetti, B.1    Fu, L.2    Moon, J.3    Bedwell, D.M.4
  • 7
    • 0029908912 scopus 로고    scopus 로고
    • A splicing-dependent regulatory mechanism that detects translation signals
    • Carter, M., S. Li, and M. Wilkinson. 1996. A splicing-dependent regulatory mechanism that detects translation signals. EMBO J. 15:5965-5975.
    • (1996) EMBO J. , vol.15 , pp. 5965-5975
    • Carter, M.1    Li, S.2    Wilkinson, M.3
  • 8
    • 0025162587 scopus 로고
    • Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA
    • Cheng, J., M. Fogel-Petrovic, and L. Maquat. 1990. Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA. Mol. Cell. Biol. 10:5215-5225.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5215-5225
    • Cheng, J.1    Fogel-Petrovic, M.2    Maquat, L.3
  • 9
    • 0027536976 scopus 로고
    • Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA
    • Cheng, J., and L. Maquat. 1993. Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Mol. Cell. Biol. 13:1892-1902.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1892-1902
    • Cheng, J.1    Maquat, L.2
  • 10
    • 0029312926 scopus 로고
    • Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5′-splice site selection
    • Chin, K., and A. M. Pyle. 1995. Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5′-splice site selection. RNA 1:391-406.
    • (1995) RNA , vol.1 , pp. 391-406
    • Chin, K.1    Pyle, A.M.2
  • 12
    • 0028934876 scopus 로고
    • Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
    • Cui, Y., K. Hagan, S. Zhang, and S. Peltz. 1995. Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev. 9:423-436.
    • (1995) Genes Dev. , vol.9 , pp. 423-436
    • Cui, Y.1    Hagan, K.2    Zhang, S.3    Peltz, S.4
  • 14
    • 0033180278 scopus 로고    scopus 로고
    • Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover
    • Czaplinski, K., M. Ruiz-Echevarria, C. Gonzalez, and S. Peltz. 1999. Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover. Bioessays 21:685-696.
    • (1999) Bioessays , vol.21 , pp. 685-696
    • Czaplinski, K.1    Ruiz-Echevarria, M.2    Gonzalez, C.3    Peltz, S.4
  • 15
    • 0023871662 scopus 로고
    • Premature translation termination mediates triosephosphate isomerase mRNA degradation
    • Daar, I., and L. Maquat. 1988. Premature translation termination mediates triosephosphate isomerase mRNA degradation. Mol. Cell. Biol. 8:802-813.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 802-813
    • Daar, I.1    Maquat, L.2
  • 16
    • 0020793569 scopus 로고
    • A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
    • Feinberg, A., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
    • (1983) Anal. Biochem. , vol.132 , pp. 6-13
    • Feinberg, A.1    Vogelstein, B.2
  • 17
    • 0029779276 scopus 로고    scopus 로고
    • Phenylalanyl-tRNA synthetase from yeast and its discrimination of 19 amino acids in aminoacylation of tRNA(Phe)-C-C-A and tRNA(Phe)-C-C-A(3′NH2)
    • Freist, W., H. Sternbach, and F. Cramer. 1996. Phenylalanyl-tRNA synthetase from yeast and its discrimination of 19 amino acids in aminoacylation of tRNA(Phe)-C-C-A and tRNA(Phe)-C-C-A(3′NH2). Eur. J. Biochem. 240:526-531.
    • (1996) Eur. J. Biochem. , vol.240 , pp. 526-531
    • Freist, W.1    Sternbach, H.2    Cramer, F.3
  • 18
    • 0033679905 scopus 로고    scopus 로고
    • The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
    • Gonzalez, C., M. Ruiz-Echevarria, S. Vasudevan, M. Henry, and S. Peltz. 2000. The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay. Mol. Cell 3:489-499.
    • (2000) Mol. Cell , vol.3 , pp. 489-499
    • Gonzalez, C.1    Ruiz-Echevarria, M.2    Vasudevan, S.3    Henry, M.4    Peltz, S.5
  • 19
    • 0030936847 scopus 로고    scopus 로고
    • Protein quality control: Triage by chaperones and proteases
    • Gottesman, S., R. Wickner, and M. R. Maurizi. 1997. Protein quality control: triage by chaperones and proteases. Genes Dev. 11:815-823.
    • (1997) Genes Dev. , vol.11 , pp. 815-823
    • Gottesman, S.1    Wickner, R.2    Maurizi, M.R.3
  • 20
    • 0025138631 scopus 로고
    • Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast
    • Gozalbo, D., and S. Hohmann. 1990. Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast. Curr. Genet. 17:77-79.
    • (1990) Curr. Genet. , vol.17 , pp. 77-79
    • Gozalbo, D.1    Hohmann, S.2
  • 21
    • 0028861358 scopus 로고
    • Characterization of cis-acting sequences and decay intermediates involved in nonsensemediated mRNA turnover
    • Hagan, K., M. Ruiz-Echevarria, Y. Quan, and S. Peltz. 1995. Characterization of cis-acting sequences and decay intermediates involved in nonsensemediated mRNA turnover. Mol. Cell. Biol. 15:809-823.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 809-823
    • Hagan, K.1    Ruiz-Echevarria, M.2    Quan, Y.3    Peltz, S.4
  • 22
    • 0024456475 scopus 로고
    • The role of mRNA and protein stability in gene expression
    • Hargrove, J. L., and F. H. Schmidt. 1989. The role of mRNA and protein stability in gene expression. FASEB J. 3:2360-2370.
    • (1989) FASEB J. , vol.3 , pp. 2360-2370
    • Hargrove, J.L.1    Schmidt, F.H.2
  • 23
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 24
    • 0028948708 scopus 로고
    • Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
    • He, F., and A. Jacobson. 1995. Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev. 9:437-454.
    • (1995) Genes Dev. , vol.9 , pp. 437-454
    • He, F.1    Jacobson, A.2
  • 26
    • 0029842901 scopus 로고    scopus 로고
    • Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast
    • He, F., A. Brown, and A. Jacobson. 1996. Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast. RNA 2:153-170.
    • (1996) RNA , vol.2 , pp. 153-170
    • He, F.1    Brown, A.2    Jacobson, A.3
  • 27
    • 0031025296 scopus 로고    scopus 로고
    • Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway
    • He, F., A. Brown, and A. Jacobson. 1997. Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol. Cell. Biol. 17:1580-1594.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1580-1594
    • He, F.1    Brown, A.2    Jacobson, A.3
  • 28
    • 0030031664 scopus 로고    scopus 로고
    • Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3
    • Henry, M., C. Z. Borland, M. Bossie, and P. A. Silver. 1996. Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics 142:103-115.
    • (1996) Genetics , vol.142 , pp. 103-115
    • Henry, M.1    Borland, C.Z.2    Bossie, M.3    Silver, P.A.4
  • 29
    • 0025267840 scopus 로고
    • Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae
    • Herrick, D., R. Parker, and A. Jacobson. 1990. Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae. Mol. Cell. Biol. 10:2269-2284.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 2269-2284
    • Herrick, D.1    Parker, R.2    Jacobson, A.3
  • 30
    • 0033375911 scopus 로고    scopus 로고
    • Mechanisms of mRNA surveillance in eukaryotes
    • Hilleren, P., and R. Parker. 1999. Mechanisms of mRNA surveillance in eukaryotes. Annu. Rev. Genet. 33:229-260.
    • (1999) Annu. Rev. Genet. , vol.33 , pp. 229-260
    • Hilleren, P.1    Parker, R.2
  • 32
    • 0027214097 scopus 로고
    • Yeast cells lacking 5′→3′ exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5′ cap structure
    • Hsu, C., and A. Stevens. 1993. Yeast cells lacking 5′→3′ exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5′ cap structure. Mol. Cell. Biol. 13:4826-4835.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4826-4835
    • Hsu, C.1    Stevens, A.2
  • 33
    • 0035839002 scopus 로고    scopus 로고
    • Coupled transcription and translation within nuclei of mammalian cells
    • Iborra, F. J., D. A. Jackson, and P. R. Cook. 2001. Coupled transcription and translation within nuclei of mammalian cells. Science 293:1139-1142.
    • (2001) Science , vol.293 , pp. 1139-1142
    • Iborra, F.J.1    Jackson, D.A.2    Cook, P.R.3
  • 34
    • 0035823036 scopus 로고    scopus 로고
    • Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
    • Ishigaki, Y., X. Li, G. Serin, and L. E. Maquat. 2001. Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell 106:607-617.
    • (2001) Cell , vol.106 , pp. 607-617
    • Ishigaki, Y.1    Li, X.2    Serin, G.3    Maquat, L.E.4
  • 35
    • 0029973094 scopus 로고    scopus 로고
    • Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
    • Jacobson, A., and S. W. Peltz. 1996. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu. Rev. Biochem. 65:693-739.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 693-739
    • Jacobson, A.1    Peltz, S.W.2
  • 36
    • 0001211084 scopus 로고    scopus 로고
    • Destabilization of nonsense-containing transcripts in Saccharomyces cerevisiae
    • J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.). Cold Spring Harbor Laboratory Press, N.Y.
    • Jacobson, A., and S. W. Peltz. 2000. Destabilization of nonsense-containing transcripts in Saccharomyces cerevisiae, p. 827-847. In J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Translational control, 2nd ed. Cold Spring Harbor Laboratory Press, N.Y.
    • (2000) Translational Control, 2nd Ed. , pp. 827-847
    • Jacobson, A.1    Peltz, S.W.2
  • 37
    • 0030475226 scopus 로고    scopus 로고
    • Fidelity of RNA polymerase II transcription controlled by elongation factor TFIIS
    • Jeon, C., and K. Agarwal. 1996. Fidelity of RNA polymerase II transcription controlled by elongation factor TFIIS. Proc. Natl. Acad. Sci. USA 93:13677-13682.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13677-13682
    • Jeon, C.1    Agarwal, K.2
  • 38
    • 0030803670 scopus 로고    scopus 로고
    • Hrp1p, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast
    • Kessler, M. M., M. F. Henry, E. Shen, J. Zhao, S. Gross, and P. A. Silver. 1997. Hrp1p, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast. Genes Dev. 11:2545-2556.
    • (1997) Genes Dev. , vol.11 , pp. 2545-2556
    • Kessler, M.M.1    Henry, M.F.2    Shen, E.3    Zhao, J.4    Gross, S.5    Silver, P.A.6
  • 39
    • 0030010752 scopus 로고    scopus 로고
    • Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA
    • Kessler, O., and L. A. Chasin. 1996. Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA. Mol. Cell. Biol. 16:4426-4435.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4426-4435
    • Kessler, O.1    Chasin, L.A.2
  • 40
    • 0035823150 scopus 로고    scopus 로고
    • Role of the nonsensemediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
    • Kim, V. N., N. Kataoka, and G. Dreyfuss. 2001. Role of the nonsensemediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Science 293:1832-1836.
    • (2001) Science , vol.293 , pp. 1832-1836
    • Kim, V.N.1    Kataoka, N.2    Dreyfuss, G.3
  • 41
    • 0028941794 scopus 로고
    • Nuclear degradation of nonsense mutated beta-globin mRNA: A post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia?
    • Kugler, W., J. Enssle, M. W. Hentze, and A. E. Kulozik. 1995. Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia? Nucleic Acids Res. 23:413-418.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 413-418
    • Kugler, W.1    Enssle, J.2    Hentze, M.W.3    Kulozik, A.E.4
  • 42
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.1
  • 43
    • 0032473359 scopus 로고    scopus 로고
    • Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme
    • LaGrandeur, T., and R. Parker. 1998. Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme. EMBO J. 17:1487-1496.
    • (1998) EMBO J. , vol.17 , pp. 1487-1496
    • LaGrandeur, T.1    Parker, R.2
  • 44
    • 0028862895 scopus 로고
    • Identification of an additional gene required for eukaryotic nonsense mRNA turnover
    • Lee, B., and M. Culbertson. 1995. Identification of an additional gene required for eukaryotic nonsense mRNA turnover. Proc. Natl. Acad. Sci. USA 92:10354-10358.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10354-10358
    • Lee, B.1    Culbertson, M.2
  • 45
    • 0026773782 scopus 로고
    • Gene products that promote mRNA turnover in Saccharomyces cerevisiae
    • Leeds, P., J. Wood, B. Lee, and M. Culbertson. 1992. Gene products that promote mRNA turnover in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:2165-2177.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2165-2177
    • Leeds, P.1    Wood, J.2    Lee, B.3    Culbertson, M.4
  • 46
    • 0025786141 scopus 로고
    • The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
    • Leeds, P., S. Peltz, A. Jacobson, and M. Culbertson. 1991. The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. Genes Dev. 5:2203-2314.
    • (1991) Genes Dev. , vol.5 , pp. 2203-2314
    • Leeds, P.1    Peltz, S.2    Jacobson, A.3    Culbertson, M.4
  • 47
    • 0034193569 scopus 로고    scopus 로고
    • Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions
    • Le Hir, H., M. J. Moore, and L. E. Maquat. 2000. Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions. Genes Dev. 14:1098-1108.
    • (2000) Genes Dev. , vol.14 , pp. 1098-1108
    • Le Hir, H.1    Moore, M.J.2    Maquat, L.E.3
  • 48
    • 0034672093 scopus 로고    scopus 로고
    • The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
    • Le Hir, H., E. Izaurralde, L. E. Maquat, and M. J. Moore. 2000. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J. 19:6860-6869.
    • (2000) EMBO J. , vol.19 , pp. 6860-6869
    • Le Hir, H.1    Izaurralde, E.2    Maquat, L.E.3    Moore, M.J.4
  • 49
    • 0009461277 scopus 로고
    • Interference of nonsense mutations with eukaryotic messenger RNA stability
    • Losson, R., and F. Lacroute. 1979. Interference of nonsense mutations with eukaryotic messenger RNA stability. Proc. Natl. Acad. Sci. USA 76:5134-5137.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5134-5137
    • Losson, R.1    Lacroute, F.2
  • 50
    • 0028147091 scopus 로고
    • Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing
    • Lozano, F., B. Maertzdorf, R. Pannell, and C. Milstein. 1994. Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. EMBO J. 13:4617-4622.
    • (1994) EMBO J. , vol.13 , pp. 4617-4622
    • Lozano, F.1    Maertzdorf, B.2    Pannell, R.3    Milstein, C.4
  • 51
    • 0035823247 scopus 로고    scopus 로고
    • Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
    • Lykke-Andersen, J., M. D. Shu, and J. A. Steitz. 2001. Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1. Science 293:1836-1839.
    • (2001) Science , vol.293 , pp. 1836-1839
    • Lykke-Andersen, J.1    Shu, M.D.2    Steitz, J.A.3
  • 52
    • 0034043404 scopus 로고    scopus 로고
    • Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
    • Maderazo, A., F. He, D. Mangus, and A. Jacobson. 2000. Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p. Mol. Cell. Biol. 20:4591-4603.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4591-4603
    • Maderazo, A.1    He, F.2    Mangus, D.3    Jacobson, A.4
  • 53
    • 0032824911 scopus 로고    scopus 로고
    • Linking mRNA turnover and translation: Assessing the polyribosomal association of mRNA decay factors and degradative intermediates
    • Mangus, D., and A. Jacobson. 1999. Linking mRNA turnover and translation: assessing the polyribosomal association of mRNA decay factors and degradative intermediates. Methods 17:28-37.
    • (1999) Methods , vol.17 , pp. 28-37
    • Mangus, D.1    Jacobson, A.2
  • 55
    • 0029330286 scopus 로고
    • When cells stop making sense: Effects of nonsense codons on RNA metabolism in vertebrate cells
    • Maquat, L. 1995. When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. RNA 1:453-465.
    • (1995) RNA , vol.1 , pp. 453-465
    • Maquat, L.1
  • 56
    • 0002650836 scopus 로고    scopus 로고
    • Nonsense-mediated RNA decay in mammalian cells: A splicing-dependent means to down-regulate the levels of mRNAs that prematurely terminate translation
    • J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.). Cold Spring Harbor Laboratory Press, N.Y.
    • Maquat, L. E. 2000. Nonsense-mediated RNA decay in mammalian cells: a splicing-dependent means to down-regulate the levels of mRNAs that prematurely terminate translation, p. 849-868. In J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Translational control, 2nd ed. Cold Spring Harbor Laboratory Press, N.Y.
    • (2000) Translational Control, 2nd Ed. , pp. 849-868
    • Maquat, L.E.1
  • 58
    • 0031436408 scopus 로고    scopus 로고
    • The presence of an intron within the rat gene for selenium-dependent glutathione peroxidase 1 is not required to protect nuclear RNA from UGA-mediated decay
    • Moriarty, P. M., C. C. Reddy, and L. E. Maquat. 1997. The presence of an intron within the rat gene for selenium-dependent glutathione peroxidase 1 is not required to protect nuclear RNA from UGA-mediated decay. RNA 3:1369-1373.
    • (1997) RNA , vol.3 , pp. 1369-1373
    • Moriarty, P.M.1    Reddy, C.C.2    Maquat, L.E.3
  • 59
    • 0031896755 scopus 로고    scopus 로고
    • Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA
    • Moriarty, P. M., C. C. Reddy, and L. E. Maquat. 1998. Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA. Mol. Cell. Biol. 18:2932-2939.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2932-2939
    • Moriarty, P.M.1    Reddy, C.C.2    Maquat, L.E.3
  • 60
    • 0027932513 scopus 로고
    • Premature translation termination triggers mRNA decapping
    • Muhlrad, D., and R. Parker. 1994. Premature translation termination triggers mRNA decapping. Nature 370:578-581.
    • (1994) Nature , vol.370 , pp. 578-581
    • Muhlrad, D.1    Parker, R.2
  • 61
    • 0032880399 scopus 로고    scopus 로고
    • Aberrant mRNAs with extended 3′ UTRs are substrates for rapid degradation by mRNA surveillance
    • Muhlrad, D., and R. Parker. 1999. Aberrant mRNAs with extended 3′ UTRs are substrates for rapid degradation by mRNA surveillance. RNA 5:1299-1307.
    • (1999) RNA , vol.5 , pp. 1299-1307
    • Muhlrad, D.1    Parker, R.2
  • 62
    • 0028202495 scopus 로고
    • Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→3′ digestion of the transcript
    • Muhlrad, D., C. Decker, and R. Parker. 1994. Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→3′ digestion of the transcript. Genes Dev. 8:855-866.
    • (1994) Genes Dev. , vol.8 , pp. 855-866
    • Muhlrad, D.1    Decker, C.2    Parker, R.3
  • 63
    • 0035478437 scopus 로고    scopus 로고
    • Is the nucleus in need of translation?
    • Pederson, T. 2001. Is the nucleus in need of translation? Trends Cell Biol. 11:395-397.
    • (2001) Trends Cell Biol. , vol.11 , pp. 395-397
    • Pederson, T.1
  • 64
    • 0002571625 scopus 로고
    • Identification of the cis-acting sequences and trans-acting factors involved in nonsense-mediated mRNA decay
    • A. Brown, M. Tuite, and J. McCarthy (ed.). Springer-Verlag, Berlin, German
    • Peltz, S., C. Trotta, F. He, A. Brown, J. Donahue, E. Welch, and A. Jacobson. 1993. Identification of the cis-acting sequences and trans-acting factors involved in nonsense-mediated mRNA decay, p. 1-10. In A. Brown, M. Tuite, and J. McCarthy (ed.), Protein synthesis and targeting in yeast. Springer-Verlag, Berlin, German.
    • (1993) Protein Synthesis and Targeting in Yeast , pp. 1-10
    • Peltz, S.1    Trotta, C.2    He, F.3    Brown, A.4    Donahue, J.5    Welch, E.6    Jacobson, A.7
  • 65
    • 0026445513 scopus 로고
    • A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae
    • Peltz, S., J. L. Donahue, and A. Jacobson. 1992. A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:5778-5784.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5778-5784
    • Peltz, S.1    Donahue, J.L.2    Jacobson, A.3
  • 66
    • 0027219029 scopus 로고
    • mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor
    • Peltz, S., A. Brown, and A. Jacobson. 1993. mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes Dev. 7:1737-1754.
    • (1993) Genes Dev. , vol.7 , pp. 1737-1754
    • Peltz, S.1    Brown, A.2    Jacobson, A.3
  • 67
    • 0027382460 scopus 로고
    • mRNA surveillance by the Caenorhabditis elegans smg genes
    • Pulak, R., and P. Anderson. 1993. mRNA surveillance by the Caenorhabditis elegans smg genes. Genes Dev. 7:1885-1897.
    • (1993) Genes Dev. , vol.7 , pp. 1885-1897
    • Pulak, R.1    Anderson, P.2
  • 68
    • 0034928832 scopus 로고    scopus 로고
    • Nonsense-mediated decay of human HEXA mRNA
    • Rajavel, K. S., and E. F. Neufeld. 2001. Nonsense-mediated decay of human HEXA mRNA. Mol. Cell. Biol. 21:5512-5519.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5512-5519
    • Rajavel, K.S.1    Neufeld, E.F.2
  • 70
    • 18844463753 scopus 로고    scopus 로고
    • Identifying the right stop: Determining how the surveillance complex recognizes and degrades an aberrant mRNA
    • Ruiz-Echevarria, M. J., C. I. Gonzalez, and S. W. Peltz. 1998. Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA. EMBO J. 17:575-589.
    • (1998) EMBO J. , vol.17 , pp. 575-589
    • Ruiz-Echevarria, M.J.1    Gonzalez, C.I.2    Peltz, S.W.3
  • 73
    • 0031720742 scopus 로고    scopus 로고
    • A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence
    • Shirley, R., M. Lelivelt, L. Schenkman, J. Dahlseid, and M. Culbertson. 1998. A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence. J. Cell Sci. 111:3129-3143.
    • (1998) J. Cell Sci. , vol.111 , pp. 3129-3143
    • Shirley, R.1    Lelivelt, M.2    Schenkman, L.3    Dahlseid, J.4    Culbertson, M.5
  • 74
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.1    Hieter, P.2
  • 75
    • 0027432273 scopus 로고
    • Parameters affecting lithium acetate-mediated transformation of Saccharomyces cerevisiae and development of a rapid and simplified procedure
    • Soni, R., J. Carmichael, and J. Murray. 1993. Parameters affecting lithium acetate-mediated transformation of Saccharomyces cerevisiae and development of a rapid and simplified procedure. Curr. Genet. 24:455-459.
    • (1993) Curr. Genet. , vol.24 , pp. 455-459
    • Soni, R.1    Carmichael, J.2    Murray, J.3
  • 76
    • 0030432607 scopus 로고    scopus 로고
    • Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes
    • Stephenson, L., and L. Maquat. 1996. Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes. Biochimie 78:1043-1047.
    • (1996) Biochimie , vol.78 , pp. 1043-1047
    • Stephenson, L.1    Maquat, L.2
  • 77
    • 0025201631 scopus 로고
    • The ADE2 gene from Saccharomyces cerevisiae: Sequence and new vectors
    • Stotz, A., and P. Linder. 1990. The ADE2 gene from Saccharomyces cerevisiae: sequence and new vectors. Gene 95:91-98.
    • (1990) Gene , vol.95 , pp. 91-98
    • Stotz, A.1    Linder, P.2
  • 78
    • 0034282528 scopus 로고    scopus 로고
    • Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position
    • Sun, X., P. M. Moriarty, and L. E. Maquat. 2000. Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position. EMBO J. 19:4734-4744.
    • (2000) EMBO J. , vol.19 , pp. 4734-4744
    • Sun, X.1    Moriarty, P.M.2    Maquat, L.E.3
  • 79
    • 0035865408 scopus 로고    scopus 로고
    • The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
    • Wang, W., K. Czaplinski, Y. Rao, and S. W. Peltz. 2001. The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts. EMBO J. 20:880-890.
    • (2001) EMBO J. , vol.20 , pp. 880-890
    • Wang, W.1    Czaplinski, K.2    Rao, Y.3    Peltz, S.W.4
  • 81
    • 0033229867 scopus 로고    scopus 로고
    • An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA
    • Welch, E., and A. Jacobson. 1999. An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA. EMBO J. 18:6134-6145.
    • (1999) EMBO J. , vol.18 , pp. 6134-6145
    • Welch, E.1    Jacobson, A.2
  • 82
    • 0029790557 scopus 로고    scopus 로고
    • Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover
    • Weng, Y., K. Czaplinski, and S. W. Peltz. 1996. Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover. Mol. Cell. Biol. 16:5491-5506.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5491-5506
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 83
    • 0029791449 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein
    • Weng, Y., K. Czaplinski, and S. W. Peltz. 1996. Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein. Mol. Cell. Biol. 16:5477-5590.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5477-5590
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 85
    • 0026549786 scopus 로고
    • Proofreading, NTPases and translation: Successful increase in specificity
    • Yarns, M. 1992. Proofreading, NTPases and translation: successful increase in specificity. Trends Biochem. Sci. 17:171-174.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 171-174
    • Yarns, M.1
  • 86
    • 0029837734 scopus 로고    scopus 로고
    • Purines are required at the 5′ ends of newly initiated RNAs for optimal RNA polymerase III gene expression
    • Zecherle, G., S. Whelen, and B. Hall. 1996. Purines are required at the 5′ ends of newly initiated RNAs for optimal RNA polymerase III gene expression. Mol. Cell. Biol. 16:5801-5810.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5801-5810
    • Zecherle, G.1    Whelen, S.2    Hall, B.3
  • 87
    • 0031840487 scopus 로고    scopus 로고
    • At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: A possible link between nuclear splicing and cytoplasmic translation
    • Zhang, J., X. Sun, Y. Qian, J. P. LaDuca, and L. E. Maquat. 1998. At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation. Mol. Cell. Biol. 18:5272-5283.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5272-5283
    • Zhang, J.1    Sun, X.2    Qian, Y.3    LaDuca, J.P.4    Maquat, L.E.5
  • 88
    • 0031870169 scopus 로고    scopus 로고
    • Intron function in the nonsense-mediated decay of beta-globin mRNA: Indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm
    • Zhang, J., X. Sun, Y. Qian, and L. E. Maquat. 1998. Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm. RNA 4:801-815.
    • (1998) RNA , vol.4 , pp. 801-815
    • Zhang, J.1    Sun, X.2    Qian, Y.3    Maquat, L.E.4
  • 89
    • 0028945345 scopus 로고
    • Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay
    • Zhang, S., M. J. Ruiz-Echevarria, Y. Quan, and S. W. Peltz. 1995. Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay. Mol. Cell. Biol. 15:2231-2244.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2231-2244
    • Zhang, S.1    Ruiz-Echevarria, M.J.2    Quan, Y.3    Peltz, S.W.4
  • 90
    • 0030951767 scopus 로고    scopus 로고
    • Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae
    • Zhang, S., E. Welch, K. Hogan, A. Brown, S. Peltz, and A. Jacobson. 1997. Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae. RNA 3:234-244.
    • (1997) RNA , vol.3 , pp. 234-244
    • Zhang, S.1    Welch, E.2    Hogan, K.3    Brown, A.4    Peltz, S.5    Jacobson, A.6
  • 91
    • 0029066943 scopus 로고
    • Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein
    • Zieler, H. A., M. Walberg, and P. Berg. 1995. Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein. Mol. Cell. Biol. 15:3227-3237.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3227-3237
    • Zieler, H.A.1    Walberg, M.2    Berg, P.3


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