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Volumn 17, Issue 2, 1998, Pages 575-589

Identifying the right stop: Determining how the surveillance complex recognizes and degrades an aberrant mRNA

Author keywords

cis acting instability elements; cis acting stability elements; mRNA decay; Nonsense mutations; Translation termination

Indexed keywords

MESSENGER RNA;

EID: 18844463753     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.2.575     Document Type: Article
Times cited : (117)

References (58)
  • 1
    • 0026085424 scopus 로고
    • Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control
    • Abastado, J.P., Miller, P.M., Jackson, B.M. and Hinnebusch, A.G. (1991a) Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control. Mol. Cell. Biol., 11, 486-496.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 486-496
    • Abastado, J.P.1    Miller, P.M.2    Jackson, B.M.3    Hinnebusch, A.G.4
  • 2
    • 0025728532 scopus 로고
    • A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae
    • Abastado, J.P., Miller, P.M. Jackson, B.M. and Hinnebusch, A.G. (1991b) A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae. The New Biologist, 3, 511-524.
    • (1991) The New Biologist , vol.3 , pp. 511-524
    • Abastado, J.P.1    Miller, P.M.2    Jackson, B.M.3    Hinnebusch, A.G.4
  • 3
    • 0027399313 scopus 로고
    • Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3′ noncoding region is mediated by a cotranslational mechanism
    • Aharon, T. and Schneider, R.J. (1993) Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3′ noncoding region is mediated by a cotranslational mechanism. Mol. Cell. Biol., 13, 1971-1980.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1971-1980
    • Aharon, T.1    Schneider, R.J.2
  • 4
    • 0030466725 scopus 로고    scopus 로고
    • The catalytic subunit of protein phosphatase 2A associates with the translation termination factor eRF1
    • Andjelkovic, N., Zolnierowicz, S., Van Hoof, C., Goris, J. and Hemmings, B.A. (1996) The catalytic subunit of protein phosphatase 2A associates with the translation termination factor eRF1. EMBO J., 15, 7156-7167.
    • (1996) EMBO J. , vol.15 , pp. 7156-7167
    • Andjelkovic, N.1    Zolnierowicz, S.2    Van Hoof, C.3    Goris, J.4    Hemmings, B.A.5
  • 6
    • 0028225993 scopus 로고
    • Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA
    • Beelman, C.A. and Parker, R. (1994) Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA. J. Biol. Chem., 269, 9687-9692.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9687-9692
    • Beelman, C.A.1    Parker, R.2
  • 7
    • 0029909497 scopus 로고    scopus 로고
    • Inhibition of nascent-peptide release at translation termination
    • Cao, J. and Geballe, A.P. (1996) Inhibition of nascent-peptide release at translation termination. Mol. Cell. Biol., 16, 7109-7114.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 7109-7114
    • Cao, J.1    Geballe, A.P.2
  • 8
    • 0029871812 scopus 로고    scopus 로고
    • Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae
    • Caponigro, G. and Parker, R. (1996) Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol. Rev., 60, 233-249.
    • (1996) Microbiol. Rev. , vol.60 , pp. 233-249
    • Caponigro, G.1    Parker, R.2
  • 9
    • 0002352428 scopus 로고    scopus 로고
    • Protein kinases that phosphorylate eIF2 and eIF2B, and their role in eukaryotic cell translational control
    • Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Clemens, M.J. (1996) Protein kinases that phosphorylate eIF2 and eIF2B, and their role in eukaryotic cell translational control. In Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Translational Control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 139-172.
    • (1996) Translational Control , pp. 139-172
    • Clemens, M.J.1
  • 10
    • 0028801330 scopus 로고
    • Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5′ to the ARE
    • Curatola, A.M., Nadal, M.S. and Schneider, R. (1995) Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5′ to the ARE. Mol. Cell. Biol., 15, 6331-6340.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6331-6340
    • Curatola, A.M.1    Nadal, M.S.2    Schneider, R.3
  • 11
    • 0028934876 scopus 로고
    • Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
    • Cui, Y., Hagan, K.W., Zhang, S. and Peltz, S.W. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev., 9, 423-436.
    • (1995) Genes Dev. , vol.9 , pp. 423-436
    • Cui, Y.1    Hagan, K.W.2    Zhang, S.3    Peltz, S.W.4
  • 12
    • 0027261517 scopus 로고
    • Four novel FBN1 mutations: Significance for mutant transcript level and EGF-like domain calcium binding in the pathogenesis of Marfan syndrome
    • Dietz, H.C., McIntosh, I., Sakai, L.Y., Corson, G.M., Chalberg, S.C., Pyeritz, R.E. and Francomano, C.A. (1993) Four novel FBN1 mutations: significance for mutant transcript level and EGF-like domain calcium binding in the pathogenesis of Marfan syndrome. Genomics, 17, 469-475.
    • (1993) Genomics , vol.17 , pp. 469-475
    • Dietz, H.C.1    McIntosh, I.2    Sakai, L.Y.3    Corson, G.M.4    Chalberg, S.C.5    Pyeritz, R.E.6    Francomano, C.A.7
  • 14
    • 0030936847 scopus 로고    scopus 로고
    • Protein quality control: Triage by chaperones and proteases
    • Gottesman, S., Wickner, S. and Maurizi, M.R. (1997) Protein quality control: triage by chaperones and proteases. Genes Dev., 11, 815-823.
    • (1997) Genes Dev. , vol.11 , pp. 815-823
    • Gottesman, S.1    Wickner, S.2    Maurizi, M.R.3
  • 15
    • 0028784458 scopus 로고
    • Sequences 5′ of the first upstream open reading frame in GCN4 mRNA are required for efficient translation reinitiation
    • Grant, C.M., Miller, P.M. and Hinnebusch, A.G. (1995) Sequences 5′ of the first upstream open reading frame in GCN4 mRNA are required for efficient translation reinitiation. Nucleic Acid Res., 23, 3980-3988.
    • (1995) Nucleic Acid Res. , vol.23 , pp. 3980-3988
    • Grant, C.M.1    Miller, P.M.2    Hinnebusch, A.G.3
  • 16
    • 0023666085 scopus 로고
    • Translation is required for degradation of histone mRNA degradation
    • Graves, R.A., Pandey, N.B., Chodchoy, N. and Marzluff, W.F. (1987) Translation is required for degradation of histone mRNA degradation. Cell, 48, 615-626.
    • (1987) Cell , vol.48 , pp. 615-626
    • Graves, R.A.1    Pandey, N.B.2    Chodchoy, N.3    Marzluff, W.F.4
  • 17
    • 0028861358 scopus 로고
    • Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover
    • Hagan, K.W., Ruiz-Echevarria, M.J., Quan, Y. and Peltz, S.W. (1995) Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover. Mol. Cell. Biol., 15, 809-823.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 809-823
    • Hagan, K.W.1    Ruiz-Echevarria, M.J.2    Quan, Y.3    Peltz, S.W.4
  • 18
    • 0028344092 scopus 로고
    • Nonsense codons mutations in the internal exon of the β-globin gene are not associated with a reduction in β-mRNa accumulation: A mechanism for the phenotype of dominant β-thalassemia
    • Hall, G.W. and Thein, S. (1994) Nonsense codons mutations in the internal exon of the β-globin gene are not associated with a reduction in β-mRNA accumulation: a mechanism for the phenotype of dominant β-thalassemia. Blood, 83, 2031-2037.
    • (1994) Blood , vol.83 , pp. 2031-2037
    • Hall, G.W.1    Thein, S.2
  • 19
    • 0028948708 scopus 로고
    • Identification of a novel component of the nonsense-mediated mRNA decay pathway using an interacting protein screen
    • He, F. and Jacobson, A. (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway using an interacting protein screen. Genes Dev., 9, 437-459.
    • (1995) Genes Dev. , vol.9 , pp. 437-459
    • He, F.1    Jacobson, A.2
  • 20
    • 0031025296 scopus 로고    scopus 로고
    • Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway
    • He, F. Brown, A.H. and Jacobson, A. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol. Cell. Biol., 17, 1580-1594.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1580-1594
    • He, F.1    Brown, A.H.2    Jacobson, A.3
  • 21
    • 0024797894 scopus 로고
    • Protein phosphorylation controls translational rates
    • Hershey, J.W.B. (1989) Protein phosphorylation controls translational rates. J. Biol. Chem., 264, 20823-20826.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20823-20826
    • Hershey, J.W.B.1
  • 22
    • 0009407476 scopus 로고
    • Evidence for translational regulation of the activator of general amino acid control in yeast
    • Hinnebusch, A.G. (1984) Evidence for translational regulation of the activator of general amino acid control in yeast. Proc. Natl Acad. Sci. USA, 81, 6442-6446.
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 6442-6446
    • Hinnebusch, A.G.1
  • 23
    • 0021846299 scopus 로고
    • A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae
    • Hinnebusch, A.G. (1985) A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. Mol. Cell. Biol., 5, 2349-2360.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2349-2360
    • Hinnebusch, A.G.1
  • 24
    • 0023901907 scopus 로고
    • Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae
    • Hinnebusch, A.G. (1988) Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae. Microbiol. Rev., 52, 248-273.
    • (1988) Microbiol. Rev. , vol.52 , pp. 248-273
    • Hinnebusch, A.G.1
  • 25
    • 0027490295 scopus 로고
    • Gene-specific translational control of the yeast GNC4 gene by phosphorylation of eukaryotic initiation factor 2
    • Hinnebusch, A.G. (1993) Gene-specific translational control of the yeast GNC4 gene by phosphorylation of eukaryotic initiation factor 2. Mol. Microbiol., 10, 215-223.
    • (1993) Mol. Microbiol. , vol.10 , pp. 215-223
    • Hinnebusch, A.G.1
  • 26
    • 0000729653 scopus 로고    scopus 로고
    • Translational control of GCN4: Gene-specific regulation by phosphorylation of eIF2
    • Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Hinnebusch, A.G. (1996) Translational control of GCN4: gene-specific regulation by phosphorylation of eIF2. In Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Translational Control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 199-244.
    • (1996) Translational Control , pp. 199-244
    • Hinnebusch, A.G.1
  • 27
    • 0020581715 scopus 로고
    • Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae
    • Hinnebusch, A.G. and Fink, G.R. (1983) Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae. J. Biol. Chem., 258, 5238-5247.
    • (1983) J. Biol. Chem. , vol.258 , pp. 5238-5247
    • Hinnebusch, A.G.1    Fink, G.R.2
  • 28
    • 0029973094 scopus 로고    scopus 로고
    • Interrelationship of the pathways of mRNA decay and translation in eukaryotic cells
    • Jacobson, A. and Peltz, S.W. (1996) Interrelationship of the pathways of mRNA decay and translation in eukaryotic cells. Annu. Rev. Biochem., 65, 693-739.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 693-739
    • Jacobson, A.1    Peltz, S.W.2
  • 29
    • 0029125496 scopus 로고
    • Identification of two KH domain proteins in the alpha-globin mRNP stability complex
    • Kiledjian, M., Wang, X. and Liebhaber, S.A. (1995) Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J., 14, 4357-4364.
    • (1995) EMBO J. , vol.14 , pp. 4357-4364
    • Kiledjian, M.1    Wang, X.2    Liebhaber, S.A.3
  • 30
    • 0028862895 scopus 로고
    • Identification of an additional gene required for eukaryotic nonsense mRNA turnover
    • Lee, B.S. and Culbertson, M.R. (1995) Identification of an additional gene required for eukaryotic nonsense mRNA turnover. Proc. Natl Acad. Sci. USA, 92, 10354-10358.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 10354-10358
    • Lee, B.S.1    Culbertson, M.R.2
  • 31
    • 0025786141 scopus 로고
    • The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
    • Leeds, P., Peltz, S.W., Jacobson, A. and Culbertson, M.R. (1991) The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. Genes Dev., 5, 2303-2314.
    • (1991) Genes Dev. , vol.5 , pp. 2303-2314
    • Leeds, P.1    Peltz, S.W.2    Jacobson, A.3    Culbertson, M.R.4
  • 32
    • 0026773782 scopus 로고
    • Gene products that promote mRNA turnover in Saccharomyces cerevisiae
    • Leeds, P., Wood, J.M., Lee, B.-S. and Culbertson, M.R. (1992) Gene products that promote mRNA turnover in Saccharomyces cerevisiae. Mol. Cell. Biol., 12, 2165-2177.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2165-2177
    • Leeds, P.1    Wood, J.M.2    Lee, B.-S.3    Culbertson, M.R.4
  • 33
    • 0029330286 scopus 로고
    • When cells stop making sense: Effects of nonsense codons on RNA metabolism in vertebrate cells
    • Maquat, L.E. (1995) When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. RNA, 1, 453-465.
    • (1995) RNA , vol.1 , pp. 453-465
    • Maquat, L.E.1
  • 34
    • 0024710133 scopus 로고
    • Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control
    • Miller, P.F. and Hinnebusch, A.G. (1989) Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control. Genes Dev., 3, 1217-1225.
    • (1989) Genes Dev. , vol.3 , pp. 1217-1225
    • Miller, P.F.1    Hinnebusch, A.G.2
  • 35
    • 0022512237 scopus 로고
    • Multiple upstream AUG codons mediate translational control of GCN4
    • Mueller, P.P. and Hinnebusch, A.G. (1986) Multiple upstream AUG codons mediate translational control of GCN4. Cell, 45, 201-207.
    • (1986) Cell , vol.45 , pp. 201-207
    • Mueller, P.P.1    Hinnebusch, A.G.2
  • 36
    • 0026441426 scopus 로고
    • Mutations affecting stability and deadenylation of the yeast MFA2 transcript
    • Mulhrad, D. and Parker, R. (1992) Mutations affecting stability and deadenylation of the yeast MFA2 transcript. Genes Dev., 6, 2100-2111.
    • (1992) Genes Dev. , vol.6 , pp. 2100-2111
    • Mulhrad, D.1    Parker, R.2
  • 37
    • 0025274019 scopus 로고
    • An intron for the genes of the U3 small nucleolar RNAs of the yeast Saccharomyces cerevisiae
    • Myslinski, E., Segault, V. and Branlant, C. (1990) An intron for the genes of the U3 small nucleolar RNAs of the yeast Saccharomyces cerevisiae. Science, 247, 1213-1216.
    • (1990) Science , vol.247 , pp. 1213-1216
    • Myslinski, E.1    Segault, V.2    Branlant, C.3
  • 38
    • 0023143706 scopus 로고
    • Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis
    • Nonet, M., Scafe, C., Sexton, J. and Young, R. (1987) Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol. Cell. Biol., 7, 1602-1611.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1602-1611
    • Nonet, M.1    Scafe, C.2    Sexton, J.3    Young, R.4
  • 39
    • 0028949735 scopus 로고
    • The relationship between eukaryotic translation and mRNA stability. A short upstream reading frame strongly inhibits translational initiation and greatly accelerates mRNA degradation in the yeast Saccharomyces cerevisiae
    • Oliveira, C.C. and McCarthy, J.E.G. (1995) The relationship between eukaryotic translation and mRNA stability. A short upstream reading frame strongly inhibits translational initiation and greatly accelerates mRNA degradation in the yeast Saccharomyces cerevisiae. J. Biol. Chem., 270, 8936-8943.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8936-8943
    • Oliveira, C.C.1    McCarthy, J.E.G.2
  • 40
    • 0025304298 scopus 로고
    • Translation and a forty-two nucleotide segment within the coding region of the mRNA encoded by the MATα1 gene are involved in promoting rapid mRNA decay in yeast
    • Parker, R. and Jacobson, A. (1990) Translation and a forty-two nucleotide segment within the coding region of the mRNA encoded by the MATα1 gene are involved in promoting rapid mRNA decay in yeast Proc. Natl Acad. Sci. USA, 87, 2780-2784.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 2780-2784
    • Parker, R.1    Jacobson, A.2
  • 41
    • 0027219029 scopus 로고
    • mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor
    • Peltz, S.W., Brown, A.H. and Jacobson, A. (1993) mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes Dev., 7, 1737-1754.
    • (1993) Genes Dev. , vol.7 , pp. 1737-1754
    • Peltz, S.W.1    Brown, A.H.2    Jacobson, A.3
  • 42
    • 0026671591 scopus 로고
    • Cis- and trans-acting suppressors of a translational initiation defect at the cyc1 locus of Saccharomyces cerevisiae
    • Pinto, I., Na, J.G., Sherman, F. and Hampsey, M. (1992) cis-and trans-acting suppressors of a translational initiation defect at the cyc1 locus of Saccharomyces cerevisiae. Genetics, 132, 97-112.
    • (1992) Genetics , vol.132 , pp. 97-112
    • Pinto, I.1    Na, J.G.2    Sherman, F.3    Hampsey, M.4
  • 44
    • 0029885420 scopus 로고    scopus 로고
    • Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay
    • Ruiz-Echevarria, M.J. and Peltz, S.W. (1996) Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay. EMBO J., 15, 2810-2819.
    • (1996) EMBO J. , vol.15 , pp. 2810-2819
    • Ruiz-Echevarria, M.J.1    Peltz, S.W.2
  • 47
    • 0026648923 scopus 로고
    • Evidence for instability of mRNAs containing AUUUa motifs mediated through translation-dependent assembly of a >20S degradation complex
    • Savant-Bhonsale, S. and Cleveland, D.W. (1992) Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a >20S degradation complex. Genes Dev., 6, 1927-1939.
    • (1992) Genes Dev. , vol.6 , pp. 1927-1939
    • Savant-Bhonsale, S.1    Cleveland, D.W.2
  • 48
    • 0024799254 scopus 로고
    • High efficiency transformation of intact yeast cells using single stranded nucleic acid as a carrier
    • Schiestl, R.H. and Gietz, R.D. (1989) High efficiency transformation of intact yeast cells using single stranded nucleic acid as a carrier. Curr. Genet., 16, 339-346.
    • (1989) Curr. Genet. , vol.16 , pp. 339-346
    • Schiestl, R.H.1    Gietz, R.D.2
  • 50
    • 0028839055 scopus 로고
    • Detection and characterization of a 3′ untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability
    • Wang, X., Kiledjian, M., Weiss, I.M. and Liebhaber, S.A. (1995) Detection and characterization of a 3′ untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability. Mol. Cell. Biol., 15, 1769-1777.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1769-1777
    • Wang, X.1    Kiledjian, M.2    Weiss, I.M.3    Liebhaber, S.A.4
  • 51
    • 0028919677 scopus 로고
    • Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3′ nontranslated region
    • Weiss, I.M. and Liebhaber, S.A. (1995) Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3′ nontranslated region. Mol. Cell. Biol., 15, 2457-2465.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2457-2465
    • Weiss, I.M.1    Liebhaber, S.A.2
  • 52
    • 0029790557 scopus 로고    scopus 로고
    • Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover
    • Weng, Y. Czaplinski, K. and Peltz, S.W. (1996a) Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover. Mol. Cell. Biol., 16, 5491-5506.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5491-5506
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 53
    • 0029791449 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of the mutations in the ATPase and helicase regions of the Upf1 protein
    • Weng, Y., Czaplinski, K. and Peltz, S.W. (1996b) Genetic and biochemical characterization of the mutations in the ATPase and helicase regions of the Upf1 protein. Mol. Cell. Biol., 16, 5447-5490.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5447-5490
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 54
    • 0007010509 scopus 로고    scopus 로고
    • Characterization of the nonsense-mediated decay pathway and its effect in modulating translation termination and programmed frameshifting
    • Weng, Y., Ruiz-Echevarria, M.J., Zhang, S., Cui, Y. Czaplinski, K., Dinman, J. and Peltz, S.W. (1997) Characterization of the nonsense-mediated decay pathway and its effect in modulating translation termination and programmed frameshifting. Modern Cell Biol., 17, 241-263.
    • (1997) Modern Cell Biol. , vol.17 , pp. 241-263
    • Weng, Y.1    Ruiz-Echevarria, M.J.2    Zhang, S.3    Cui, Y.4    Czaplinski, K.5    Dinman, J.6    Peltz, S.W.7
  • 55
    • 0029032362 scopus 로고
    • Rapid mRNA degradation mediated by the c-fos 3′ AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3′ AU-rich element occur through similar polysome-associated mechanisms
    • Winstall, E., Gamache, M. and Raymond, V. (1995) Rapid mRNA degradation mediated by the c-fos 3′ AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3′ AU-rich element occur through similar polysome-associated mechanisms. Mol. Cell Biol., 15, 3796-3804.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3796-3804
    • Winstall, E.1    Gamache, M.2    Raymond, V.3
  • 56
    • 0028869817 scopus 로고
    • Initiation of translation can occur only in a restricted region of the CYC1 mRNA of Saccharomyces cerevisiae
    • Yun, D.-F. and Sherman, F. (1995) Initiation of translation can occur only in a restricted region of the CYC1 mRNA of Saccharomyces cerevisiae. Mol. Cell. Biol., 15, 1021-1033.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1021-1033
    • Yun, D.-F.1    Sherman, F.2
  • 57
    • 0031046735 scopus 로고    scopus 로고
    • Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells
    • Zhang, J. and Maquat, L.E. (1997) Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells. EMBO J., 16, 826-833.
    • (1997) EMBO J. , vol.16 , pp. 826-833
    • Zhang, J.1    Maquat, L.E.2
  • 58
    • 0028945345 scopus 로고
    • Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay
    • Zhang, S., Ruiz-Echevarria, M.J., Quan, Y. and Peltz, S.W. (1995) Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay. Mol. Cell. Biol., 15, 2231-2244.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2231-2244
    • Zhang, S.1    Ruiz-Echevarria, M.J.2    Quan, Y.3    Peltz, S.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.